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Items: 1 to 20 of 76

1.
RACK1 and IRE1 participate in the translational quality control of amyloid precursor protein in Drosophila models of Alzheimer’s disease
Yu Li, Dongyue Liu, Xuejing Zhang, Suman Rimal, Bingwei Lu, Shuangxi Li
J Biol Chem. 2024 Mar; 300(3): 105719. Published online 2024 Feb 2. doi: 10.1016/j.jbc.2024.105719
PMCID:
PMC10907166
AbstractArticlePDF–4.0M
2.
Wg/Wnt1 and Erasp link ER stress to proapoptotic signaling in an autosomal dominant retinitis pigmentosa model
Jung-Eun Park, Jiyoun Lee, Soonhyuck Ok, Seunghee Byun, Eun-Ju Chang, Sung-Eun Yoon, Young-Joon Kim, Min-Ji Kang
Exp Mol Med. 2023 Jul; 55(7): 1544–1555. Published online 2023 Jul 18. doi: 10.1038/s12276-023-01044-7
PMCID:
PMC10394004
AbstractArticlePDF–3.8M
3.
c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD
Talanjeri Gopalakrishna Sahana, Katherine Johnson Chase, Feilin Liu, Thomas E. Lloyd, Wilfried Rossoll, Ke Zhang
J Neurosci. 2023 Apr 26; 43(17): 3186–3197. doi: 10.1523/JNEUROSCI.1799-22.2023
PMCID:
PMC10146492
AbstractArticlePDF–3.9M
4.
The small compound Icerguastat reduces muscle defects in oculopharyngeal muscular dystrophy through the PERK pathway of the unfolded protein response
Rima Naït-Saïdi, Aymeric Chartier, Emmanuelle Abgueguen, Philippe Guédat, Martine Simonelig
Open Biol. 2023 Apr; 13(4): 230008. Published online April 12, 2023. doi: 10.1098/rsob.230008
PMCID:
PMC10090878
AbstractArticlePDF–1.6M
5.
PERK prevents rhodopsin degradation during retinitis pigmentosa by inhibiting IRE1-induced autophagy
Ning Zhao, Ning Li, Tao Wang
J Cell Biol. 2023 May 1; 222(5): e202208147. Published online 2023 Apr 6. doi: 10.1083/jcb.202208147
PMCID:
PMC10082367
AbstractArticlePDF–8.9M
6.
Mitochondrial remodelling is essential for female germ cell differentiation and survival
Vernon Leander Monteiro, Darya Safavian, Deepika Vasudevan, Thomas Ryan Hurd
PLoS Genet. 2023 Jan; 19(1): e1010610. Published online 2023 Jan 25. doi: 10.1371/journal.pgen.1010610
PMCID:
PMC9901744
AbstractArticlePDF–4.3M
7.
Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila
Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal
G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263
PMCID:
PMC9713431
AbstractArticlePDF–1.0M
8.
Bip-Yorkie interaction determines oncogenic and tumor-suppressive roles of Ire1/Xbp1s activation
Shuai Yang, Hua Jiang, Weixiang Bian, Wenyan Xu, Yifan Guo, Sha Song, Jiadong Zheng, Xiaoyu Kuang, Chenxi Wu, Xiang Ding, Xiaowei Guo, Lei Xue, Zijing Yu, Yongdeng Zhang, Hyung Don Ryoo, Xu Li, Xianjue Ma
Proc Natl Acad Sci U S A. 2022 Oct 18; 119(42): e2202133119. Published online 2022 Oct 10. doi: 10.1073/pnas.2202133119
PMCID:
PMC9586321
AbstractArticlePDF–4.4M
9.
Identification of Therapeutic Targets for Amyotrophic Lateral Sclerosis Using PandaOmics – An AI-Enabled Biological Target Discovery Platform
Frank W. Pun, Bonnie Hei Man Liu, Xi Long, Hoi Wing Leung, Geoffrey Ho Duen Leung, Quinlan T. Mewborne, Junli Gao, Anastasia Shneyderman, Ivan V. Ozerov, Ju Wang, Feng Ren, Alexander Aliper, Evelyne Bischof, Evgeny Izumchenko, Xiaoming Guan, Ke Zhang, Bai Lu, Jeffrey D. Rothstein, Merit E. Cudkowicz, Alex Zhavoronkov
Front Aging Neurosci. 2022; 14: 914017. Published online 2022 Jun 28. doi: 10.3389/fnagi.2022.914017
PMCID:
PMC9273868
AbstractArticlePDF–3.6M
10.
Hsian-Tsao (Mesona chinensis Benth.) Extract Improves the Thermal Tolerance of Drosophila melanogaster
Yan Huang, Pumo Cai, Xinxin Su, Mingjing Zheng, Wenwen Chi, Shaoling Lin, Zhiwei Huang, Si Qin, Shaoxiao Zeng
Front Nutr. 2022; 9: 819319. Published online 2022 May 9. doi: 10.3389/fnut.2022.819319
Correction in:
Front Nutr. 2022; 9: 953463.
PMCID:
PMC9124935
AbstractArticlePDF–15M
11.
New Drosophila models to uncover the intrinsic and extrinsic factors that mediate the toxicity of the human prion protein
Ryan R. Myers, Jonatan Sanchez-Garcia, Daniel C. Leving, Richard G. Melvin, Pedro Fernandez-Funez
Dis Model Mech. 2022 Apr 1; 15(4): dmm049184. Published online 2022 May 4. doi: 10.1242/dmm.049184
PMCID:
PMC9093039
AbstractArticle
12.
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay
Fátima Cairrão, Cristiana C. Santos, Adrien Le Thomas, Scot Marsters, Avi Ashkenazi, Pedro M. Domingos
Nat Commun. 2022; 13: 1587. Published online 2022 Mar 24. doi: 10.1038/s41467-022-29105-x
PMCID:
PMC8948244
AbstractArticlePDF–3.0M
13.
Expression of Human Mutant Preproinsulins Induced Unfolded Protein Response, Gadd45 Expression, JAK-STAT Activation, and Growth Inhibition in Drosophila
Tatsuki Yamazoe, Yasuyuki Nakahara, Hiroka Katsube, Yoshihiro H. Inoue
Int J Mol Sci. 2021 Nov; 22(21): 12038. Published online 2021 Nov 7. doi: 10.3390/ijms222112038
PMCID:
PMC8584581
AbstractArticlePDF–2.8M
14.
The transcription factor Xrp1 is required for PERK-mediated antioxidant gene induction in Drosophila
Brian Brown, Sahana Mitra, Finnegan D Roach, Deepika Vasudevan, Hyung Don Ryoo
eLife. 2021; 10: e74047. Published online 2021 Oct 4. doi: 10.7554/eLife.74047
PMCID:
PMC8514241
AbstractArticlePDF–13M
15.
Activation of IRE1, PERK and salt-inducible kinases leads to Sec body formation in Drosophila S2 cells
Chujun Zhang, Wessel van Leeuwen, Marloes Blotenburg, Angelica Aguilera-Gomez, Sem Brussee, Rianne Grond, Harm H. Kampinga, Catherine Rabouille
J Cell Sci. 2021 Sep 1; 134(17): jcs258685. Published online 2021 Sep 6. doi: 10.1242/jcs.258685
PMCID:
PMC8445602
AbstractArticle
16.
The Role of Ire1 in Drosophila Eye pigmentation Revealed by an RNase Dead Allele
Sahana Mitra, Hyung Don Ryoo
Dev Biol. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Dev Biol. 2021 Oct; 478: 205–211. Published online 2021 Jul 13. doi: 10.1016/j.ydbio.2021.07.008
PMCID:
PMC8364510
AbstractArticlePDF–1.3M
17.
Fat body Ire1 regulates lipid homeostasis through the Xbp1s-FoxO axis in Drosophila
Peng Zhao, Ping Huang, Tongfu Xu, Xiaoxiang Xiang, Ying Sun, Jingqi Liu, Cheng Yan, Lei Wang, Jiamei Gao, Shang Cui, Xiangdong Wang, Lixing Zhan, Haiyun Song, Jingnan Liu, Wei Song, Yong Liu
iScience. 2021 Aug 20; 24(8): 102819. Published online 2021 Jul 7. doi: 10.1016/j.isci.2021.102819
PMCID:
PMC8333185
AbstractArticlePDF–2.4M
18.
Secrets of secretion—how studies of the Drosophila salivary gland have informed our understanding of the cellular networks underlying secretory organ form and function
Rajprasad Loganathan, Ji Hoon Kim, Michael B. Wells, Deborah J. Andrew
Curr Top Dev Biol. Author manuscript; available in PMC 2021 Jul 1.
Published in final edited form as: Curr Top Dev Biol. 2021; 143: 1–36. Published online 2020 Nov 19. doi: 10.1016/bs.ctdb.2020.09.005
PMCID:
PMC8135252
AbstractArticlePDF–1.1M
19.
ER Stress-Sensor Proteins and ER-Mitochondrial Crosstalk—Signaling Beyond (ER) Stress Response
Vaishali Kumar, Shuvadeep Maity
Biomolecules. 2021 Feb; 11(2): 173. Published online 2021 Jan 28. doi: 10.3390/biom11020173
PMCID:
PMC7911976
AbstractArticlePDF–1.0M
20.
Ageing, metabolism and the intestine
Maja C Funk, Jun Zhou, Michael Boutros
EMBO Rep. 2020 Jul 3; 21(7): e50047. Published online 2020 Jun 21. doi: 10.15252/embr.202050047
PMCID:
PMC7332987
AbstractArticlePDF–1.3M

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