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Select item 111221211.

Transcriptomic Insights into Host Metabolism and Immunity Changes after Parasitization by Leptopilina myrica

Junwei Zhang, Jieyu Shan, Wenqi Shi, Ting Feng, Yifeng Sheng, Zixuan Xu, Zhi Dong, Jianhua Huang, Jiani Chen

Insects. 2024 May; 15(5): 352. Published online 2024 May 14. doi: 10.3390/insects15050352

PMCID:: PMC11122121

Abstract Article PDF–2.4M

Select item 104348972.

The genetic basis of variation in immune defense against Lysinibacillus fusiformis infection in Drosophila melanogaster

Brittny R. Smith, Kistie B. Patch, Anjali Gupta, Emma M. Knoles, Robert L. Unckless

PLoS Pathog. 2023 Aug; 19(8): e1010934. Published online 2023 Aug 7. doi: 10.1371/journal.ppat.1010934

PMCID:: PMC10434897

Abstract Article PDF–2.5M

Select item 104340043.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 103177844.

Interactions with ectoparasitic mites induce host metabolic and immune responses in flies at the expense of reproduction-associated factors

Joshua B. Benoit, Joy Bose, Samuel T. Bailey, Michal Polak

Parasitology. 2020 Sep; 147(11): 1196–1205. Published online 2020 Jun 5. doi: 10.1017/S0031182020000918

PMCID:: PMC10317784

Abstract Article PDF–602K

Select item 102641575.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 101633246.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 101057367.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 100792278.

Mycobacterium abscessus resists the innate cellular response by surviving cell lysis of infected phagocytes

Hamadoun Touré, Lee Ann Galindo, Marion Lagune, Simon Glatigny, Robert M. Waterhouse, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

PLoS Pathog. 2023 Mar; 19(3): e1011257. Published online 2023 Mar 27. doi: 10.1371/journal.ppat.1011257

PMCID:: PMC10079227

Abstract Article PDF–2.1M

Select item 100523499.

Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila

Judith Bossen, Ruben Prange, Jan-Philip Kühle, Sven Künzel, Xiao Niu, Jörg U. Hammel, Laura Krieger, Mirjam Knop, Birte Ehrhardt, Karin Uliczka, Susanne Krauss-Etschmann, Thomas Roeder

Int J Mol Sci. 2023 Mar; 24(6): 5628. Published online 2023 Mar 15. doi: 10.3390/ijms24065628

PMCID:: PMC10052349

Abstract Article PDF–5.6M

Select item 1004112610.

A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium

Jianqiong Huang, Yanyan Lou, Jiyong Liu, Philippe Bulet, Chuping Cai, Kaiyu Ma, Renjie Jiao, Jules A. Hoffmann, Samuel Liégeois, Zi Li, Dominique Ferrandon

Proc Natl Acad Sci U S A. 2023 Mar 21; 120(12): e2205140120. Published online 2023 Mar 14. doi: 10.1073/pnas.2205140120

PMCID:: PMC10041126

Abstract Article PDF–848K

Select item 982754811.

The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins

Rui Xu, Yanyan Lou, Antonin Tidu, Philippe Bulet, Thorsten Heinekamp, Franck Martin, Axel Brakhage, Zi Li, Samuel Liégeois, Dominique Ferrandon

EMBO Rep. 2023 Jan; 24(1): e56036. Published online 2022 Nov 2. doi: 10.15252/embr.202256036

PMCID:: PMC9827548

Abstract Article PDF–3.4M

Select item 972673312.

Hemocytes and fat body cells, the only professional immune cell types in Drosophila, show strikingly different responses to systemic infections

Vaibhvi Vaibhvi, Sven Künzel, Thomas Roeder

Front Immunol. 2022; 13: 1040510. Published online 2022 Nov 23. doi: 10.3389/fimmu.2022.1040510

PMCID:: PMC9726733

Abstract Article PDF–15M

Select item 968753913.

Shortened lifespan induced by a high-glucose diet is associated with intestinal immune dysfunction in Drosophila sechellia

Maiko Abe, Takumi Kamiyama, Yasushi Izumi, Qingyin Qian, Yuma Yoshihashi, Yousuke Degawa, Kaori Watanabe, Yukako Hattori, Tadashi Uemura, Ryusuke Niwa

J Exp Biol. 2022 Nov 1; 225(21): jeb244423. Published online 2022 Oct 31. doi: 10.1242/jeb.244423

PMCID:: PMC9687539

Abstract Article

Select item 920864814.

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-β pathway in Drosophila

Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu

Genetics. 2022 Mar; 220(3): iyab234. Published online 2021 Dec 21. doi: 10.1093/genetics/iyab234

PMCID:: PMC9208648

Abstract Article PDF–1.5M

Select item 914746315.

Meta-Analysis of Immune Induced Gene Expression Changes in Diverse Drosophila melanogaster Innate Immune Responses

Ashley L. Waring, Joshua Hill, Brooke M. Allen, Nicholas M. Bretz, Nguyen Le, Pooja Kr, Dakota Fuss, Nathan T. Mortimer

Insects. 2022 May; 13(5): 490. Published online 2022 May 23. doi: 10.3390/insects13050490

PMCID:: PMC9147463

Abstract Article PDF–1.6M

Select item 846885316.

LncRNA-CR11538 Decoys Dif/Dorsal to Reduce Antimicrobial Peptide Products for Restoring Drosophila Toll Immunity Homeostasis

Hongjian Zhou, Shengjie Li, Shanshan Wu, Ping Jin, Fei Ma

Int J Mol Sci. 2021 Sep; 22(18): 10117. Published online 2021 Sep 18. doi: 10.3390/ijms221810117

PMCID:: PMC8468853

Abstract Article PDF–30M

Select item 834161217.

First transcriptome profiling of D. melanogaster after development in a deep underground low radiation background laboratory

Mikhail Zarubin, Albert Gangapshev, Yuri Gavriljuk, Vladimir Kazalov, Elena Kravchenko

PLoS One. 2021; 16(8): e0255066. Published online 2021 Aug 5. doi: 10.1371/journal.pone.0255066

PMCID:: PMC8341612

Abstract Article PDF–1.5M

Select item 831905218.

RNA degradation is required for the germ-cell to maternal transition in Drosophila

Patrick Blatt, Siu Wah Wong-Deyrup, Alicia McCarthy, Shane Breznak, Matthew D. Hurton, Maitreyi Upadhyay, Benjamin Bennink, Justin Camacho, Miler T. Lee, Prashanth Rangan

Curr Biol. Author manuscript; available in PMC 2021 Jul 29.

Published in final edited form as: Curr Biol. 2021 Jul 26; 31(14): 2984–2994.e7. Published online 2021 May 13. doi: 10.1016/j.cub.2021.04.052

PMCID:: PMC8319052

Abstract Article PDF–2.2M

Select item 818474419.

Metabolic control of daily locomotor activity mediated by tachykinin in Drosophila

Sang Hyuk Lee, Eunjoo Cho, Sung-Eun Yoon, Youngjoon Kim, Eun Young Kim

Commun Biol. 2021; 4: 693. Published online 2021 Jun 7. doi: 10.1038/s42003-021-02219-6

PMCID:: PMC8184744

Abstract Article PDF–10M

Select item 814818520.

The Impact of Microbiome and Microbiota-Derived Sodium Butyrate on Drosophila Transcriptome and Metabolome Revealed by Multi-Omics Analysis

Fan Zhou, Biaodi Liu, Xin Liu, Yan Li, Luoluo Wang, Jia Huang, Guanzheng Luo, Xiaoyun Wang

Metabolites. 2021 May; 11(5): 298. Published online 2021 May 6. doi: 10.3390/metabo11050298

PMCID:: PMC8148185

Abstract Article PDF–28M

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