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Select item 109359541.

Mitochondrial perturbation in immune cells enhances cell-mediated innate immunity in Drosophila

Laura Vesala, Yuliya Basikhina, Tea Tuomela, Anssi Nurminen, Emilia Siukola, Pedro F. Vale, Tiina S. Salminen

BMC Biol. 2024; 22: 60. Published online 2024 Mar 13. doi: 10.1186/s12915-024-01858-5

PMCID:: PMC10935954

Abstract Article PDF–2.4M

Select item 109285822.

Single‐cell transcriptome characteristics of testicular terminal epithelium lineages during aging in the Drosophila

Xia Chen, Yujuan Qi, Qiuru Huang, Chi Sun, Yanli Zheng, Li Ji, Yi Shi, Xinmeng Cheng, Zhenbei Li, Sen Zheng, Yijuan Cao, Zhifeng Gu, Jun Yu

Aging Cell. 2024 Mar; 23(3): e14057. Published online 2023 Dec 3. doi: 10.1111/acel.14057

PMCID:: PMC10928582

Abstract Article PDF–6.7M

Select item 104340043.

Mycobacterium abscessus Opsonization Allows an Escape from the Defensin Bactericidal Action in Drosophila

Hamadoun Touré, Nicolas Durand, Isabelle Guénal, Jean-Louis Herrmann, Fabienne Girard-Misguich, Sébastien Szuplewski

Microbiol Spectr. 2023 Jul-Aug; 11(4): e00777-23. Published online 2023 Jun 1. doi: 10.1128/spectrum.00777-23

PMCID:: PMC10434004

Abstract Article PDF–1.7M

Select item 101633244.

Antimicrobial peptides do not directly contribute to aging in Drosophila, but improve lifespan by preventing dysbiosis

Mark A. Hanson, Bruno Lemaitre

Dis Model Mech. 2023 Apr 1; 16(4): dmm049965. Published online 2023 Apr 26. doi: 10.1242/dmm.049965

PMCID:: PMC10163324

Abstract Article

Select item 101057365.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 100663526.

Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type Drosophila

Di Chen, Xiao Lan, Xiaoming Huang, Jieqing Huang, Xiaojing Zhou, Zhichao Miao, Yuting Ma, Akira Goto, Shanming Ji, Jules A. Hoffmann

J Innate Immun. 2023 Jan-Dec; 15(1): 442–467. Published online 2023 Mar 30. doi: 10.1159/000529096

PMCID:: PMC10066352

Abstract Article PDF–6.1M

Select item 100523497.

Adult and Larval Tracheal Systems Exhibit Different Molecular Architectures in Drosophila

Judith Bossen, Ruben Prange, Jan-Philip Kühle, Sven Künzel, Xiao Niu, Jörg U. Hammel, Laura Krieger, Mirjam Knop, Birte Ehrhardt, Karin Uliczka, Susanne Krauss-Etschmann, Thomas Roeder

Int J Mol Sci. 2023 Mar; 24(6): 5628. Published online 2023 Mar 15. doi: 10.3390/ijms24065628

PMCID:: PMC10052349

Abstract Article PDF–5.6M

Select item 97267338.

Hemocytes and fat body cells, the only professional immune cell types in Drosophila, show strikingly different responses to systemic infections

Vaibhvi Vaibhvi, Sven Künzel, Thomas Roeder

Front Immunol. 2022; 13: 1040510. Published online 2022 Nov 23. doi: 10.3389/fimmu.2022.1040510

PMCID:: PMC9726733

Abstract Article PDF–15M

Select item 96714439.

Trans-regulatory changes underpin the evolution of the Drosophila immune response

Shuai Dominique Ding, Alexandre B. Leitão, Jonathan P. Day, Ramesh Arunkumar, Morgan Phillips, Shuyu Olivia Zhou, Francis M. Jiggins

PLoS Genet. 2022 Nov; 18(11): e1010453. Published online 2022 Nov 7. doi: 10.1371/journal.pgen.1010453

PMCID:: PMC9671443

Abstract Article PDF–2.2M

Select item 963564410.

Enteric bacterial infection in Drosophila induces whole-body alterations in metabolic gene expression independently of the immune deficiency signaling pathway

Rujuta Deshpande, Byoungchun Lee, Savraj S Grewal

G3 (Bethesda) 2022 Nov; 12(11): jkac163. Published online 2022 Jul 4. doi: 10.1093/g3journal/jkac163

PMCID:: PMC9635644

Abstract Article PDF–2.2M

Select item 958355311.

HP1a-mediated heterochromatin formation promotes antimicrobial responses against Pseudomonas aeruginosa infection

Po-Jen Wu, Shian-Jang Yan

BMC Biol. 2022; 20: 234. Published online 2022 Oct 20. doi: 10.1186/s12915-022-01435-8

PMCID:: PMC9583553

Abstract Article PDF–7.6M

Select item 920864812.

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle-mediated TGF-β pathway in Drosophila

Xiaofen Wu, Kongyan Niu, Xiaofan Wang, Jing Zhao, Han Wang, Dean Li, Hui Wang, Ting Miao, Yun Yang, Huanhuan Ma, Yaoyang Zhang, Lei Pan, Rui Liu, Hua Bai, Nan Liu

Genetics. 2022 Mar; 220(3): iyab234. Published online 2021 Dec 21. doi: 10.1093/genetics/iyab234

PMCID:: PMC9208648

Abstract Article PDF–1.5M

Select item 917449513.

Dietary restriction and the transcription factor clock delay eye aging to extend lifespan in Drosophila Melanogaster

Brian A. Hodge, Geoffrey T. Meyerhof, Subhash D. Katewa, Ting Lian, Charles Lau, Sudipta Bar, Nicole Y. Leung, Menglin Li, David Li-Kroeger, Simon Melov, Birgit Schilling, Craig Montell, Pankaj Kapahi

Nat Commun. 2022; 13: 3156. Published online 2022 Jun 7. doi: 10.1038/s41467-022-30975-4

PMCID:: PMC9174495

Abstract Article PDF–2.6M

Select item 914746314.

Meta-Analysis of Immune Induced Gene Expression Changes in Diverse Drosophila melanogaster Innate Immune Responses

Ashley L. Waring, Joshua Hill, Brooke M. Allen, Nicholas M. Bretz, Nguyen Le, Pooja Kr, Dakota Fuss, Nathan T. Mortimer

Insects. 2022 May; 13(5): 490. Published online 2022 May 23. doi: 10.3390/insects13050490

PMCID:: PMC9147463

Abstract Article PDF–1.6M

Select item 879149815.

Bart van Alphen, Samuel Stewart, Marta Iwanaszko, Fangke Xu, Keyin Li, Sydney Rozenfeld, Anujaianthi Ramakrishnan, Taichi Q. Itoh, Shiju Sisobhan, Zuoheng Qin, Bridget C. Lear, Ravi Allada

PLoS Biol. 2022 Jan; 20(1): e3001456. Published online 2022 Jan 26. doi: 10.1371/journal.pbio.3001456

PMCID:: PMC8791498

Abstract Article PDF–2.8M

Select item 873363216.

Cecropins contribute to Drosophila host defense against a subset of fungal and Gram-negative bacterial infection

Alexia L Carboni, Mark A Hanson, Scott A Lindsay, Steven A Wasserman, Bruno Lemaitre

Genetics. 2022 Jan; 220(1): iyab188. Published online 2021 Nov 15. doi: 10.1093/genetics/iyab188

PMCID:: PMC8733632

Abstract Article PDF–787K

Select item 864519717.

Transcriptomic evidence for a trade‐off between germline proliferation and immunity in Drosophila

Marisa A. Rodrigues, Antoine Merckelbach, Esra Durmaz, Envel Kerdaffrec, Thomas Flatt

Evol Lett. 2021 Dec; 5(6): 644–656. Published online 2021 Oct 21. doi: 10.1002/evl3.261

PMCID:: PMC8645197

Abstract Article PDF–1002K

Select item 861049318.

Paths and pathways that generate cell-type heterogeneity and developmental progression in hematopoiesis

Juliet R Girard, Lauren M Goins, Dung M Vuu, Mark S Sharpley, Carrie M Spratford, Shreya R Mantri, Utpal Banerjee

eLife. 2021; 10: e67516. Published online 2021 Oct 29. doi: 10.7554/eLife.67516

PMCID:: PMC8610493

Abstract Article PDF–13M

Select item 860751319.

CHD1 controls H3.3 incorporation in adult brain chromatin to maintain metabolic homeostasis and normal lifespan

Ines Schoberleitner, Ingo Bauer, Anming Huang, Evgeniya N. Andreyeva, Johanna Sebald, Katharina Pascher, Dietmar Rieder, Melanie Brunner, Valerie Podhraski, Gregor Oemer, Daniel Cázarez-García, Leila Rieder, Markus A. Keller, Robert Winkler, Dmitry V. Fyodorov, Alexandra Lusser

Cell Rep. Author manuscript; available in PMC 2021 Nov 22.

Published in final edited form as: Cell Rep. 2021 Oct 5; 37(1): 109769. doi: 10.1016/j.celrep.2021.109769

PMCID:: PMC8607513

Abstract Article PDF–1.1M

Select item 840616920.

Drosophila Antimicrobial Peptides and Lysozymes Regulate Gut Microbiota Composition and Abundance

A. Marra, M. A. Hanson, S. Kondo, B. Erkosar, B. Lemaitre

mBio. 2021 Jul-Aug; 12(4): e00824-21. Published online 2021 Jul 13. doi: 10.1128/mBio.00824-21

PMCID:: PMC8406169

Abstract Article PDF–2.9M

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