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Select item 96429981.

A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene

Yonghe Ding, Di Lang, Jianhua Yan, Haisong Bu, Hongsong Li, Kunli Jiao, Jingchun Yang, Haibo Ni, Stefano Morotti, Tai Le, Karl J Clark, Jenna Port, Stephen C Ekker, Hung Cao, Yuji Zhang, Jun Wang, Eleonora Grandi, Zhiqiang Li, Yongyong Shi, Yigang Li, Alexey V Glukhov, Xiaolei Xu

eLife. 2022; 11: e77327. Published online 2022 Oct 18. doi: 10.7554/eLife.77327

PMCID:: PMC9642998

Abstract Article PDF–2.1M

Select item 79689252.

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam

eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873

PMCID:: PMC7968925

Abstract Article PDF–4.0M

Select item 78695153.

A novel recessive mutation affecting DNAJB6a causes myofibrillar myopathy

Fang-Yuan Qian, Yu-Dong Guo, Juan Zu, Jin-Hua Zhang, Yi-Ming Zheng, Idriss Ali Abdoulaye, Zhao-Hui Pan, Chun-Ming Xie, Han-Chao Gao, Zhi-Jun Zhang

Acta Neuropathol Commun. 2021; 9: 23. Published online 2021 Feb 8. doi: 10.1186/s40478-020-01046-w

PMCID:: PMC7869515

Abstract Article PDF–13M

Select item 74100714.

Inhibition of DNAJ-HSP70 interaction improves strength in muscular dystrophy

Rocio Bengoechea, Andrew R. Findlay, Ankan K. Bhadra, Hao Shao, Kevin C. Stein, Sara K. Pittman, Jil A.W. Daw, Jason E. Gestwicki, Heather L. True, Conrad C. Weihl

J Clin Invest. 2020 Aug 3; 130(8): 4470–4485. Published online 2020 Jul 20. doi: 10.1172/JCI136167

PMCID:: PMC7410071

Abstract Article PDF–16M

Select item 72950335.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 63334606.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 62441837.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 59277718.

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

Gian-Luca McLelland, Thomas Goiran, Wei Yi, Geneviève Dorval, Carol X Chen, Nadine D Lauinger, Andrea I Krahn, Sepideh Valimehr, Aleksandar Rakovic, Isabelle Rouiller, Thomas M Durcan, Jean-François Trempe, Edward A Fon

eLife. 2018; 7: e32866. Published online 2018 Apr 20. doi: 10.7554/eLife.32866

PMCID:: PMC5927771

Abstract Article PDF–9.1M

Select item 56656439.

CHIP as a membrane-shuttling proteostasis sensor

Yannick Kopp, Wei-Han Lang, Tobias B Schuster, Adrián Martínez-Limón, Harald F Hofbauer, Robert Ernst, Giulia Calloni, R Martin Vabulas

eLife. 2017; 6: e29388. Published online 2017 Nov 1. doi: 10.7554/eLife.29388

PMCID:: PMC5665643

Abstract Article PDF–2.2M

Select item 538122610.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 534152011.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 478790312.

The ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes

Markus M. Rinschen, Puneet Bharill, Xiongwu Wu, Priyanka Kohli, Matthäus J. Reinert, Oliver Kretz, Isabel Saez, Bernhard Schermer, Martin Höhne, Malte P. Bartram, Sriram Aravamudhan, Bernard R. Brooks, David Vilchez, Tobias B. Huber, Roman-Ulrich Müller, Marcus Krüger, Thomas Benzing

Hum Mol Genet. 2016 Apr 1; 25(7): 1328–1344. Published online 2016 Jan 19. doi: 10.1093/hmg/ddw016

PMCID:: PMC4787903

Abstract Article PDF–1.0M

Select item 357241013.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 344801214.

Transcription factor Foxp3 and its protein partners form a complex regulatory network

Dipayan Rudra, Paul deRoos, Ashutosh Chaudhry, Rachel Niec, Aaron Arvey, Robert M. Samstein, Christina Leslie, Scott A. Shaffer, David R. Goodlett, Alexander Y. Rudensky

Nat Immunol. Author manuscript; available in PMC 2013 Apr 1.

Published in final edited form as: Nat Immunol. 2012 Oct; 13(10): 1010–1019. Published online 2012 Aug 26. doi: 10.1038/ni.2402

PMCID:: PMC3448012

Abstract Article PDF–2.6M

Select item 318272015.

Forkhead factor FoxO1 is essential for placental morphogenesis in the developing embryo

Anwarul Ferdous, Jesse Morris, Mohammad Joynal Abedin, Shandon Collins, James A. Richardson, Joseph A. Hill

Proc Natl Acad Sci U S A. 2011 Sep 27; 108(39): 16307–16312. Published online 2011 Sep 19. doi: 10.1073/pnas.1107341108

PMCID:: PMC3182720

Abstract Article PDF–820K

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253417.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 255627018.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

Select item 157869719.

Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo

Alexei V. Evsikov, Joel H. Graber, J. Michael Brockman, Aleš Hampl, Andrea E. Holbrook, Priyam Singh, John J. Eppig, Davor Solter, Barbara B. Knowles

Genes Dev. 2006 Oct 1; 20(19): 2713–2727. doi: 10.1101/gad.1471006

PMCID:: PMC1578697

Abstract Article PDF–1.7M

Select item 128027820.

Yan-Shan Dai, Jian Xu, Jeffery D. Molkentin

Mol Cell Biol. 2005 Nov; 25(22): 9936–9948. doi: 10.1128/MCB.25.22.9936-9948.2005

PMCID:: PMC1280278

Abstract Article PDF–615K

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