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Items: 1 to 20 of 35

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Paraoxonase 2 (PON2) plays a limited role in murine lung tumorigenesis
Aaron G. Whitt, Aaron M. Neely, Omar Sadi Sarkar, Shuhan Meng, Sengodagounder Arumugam, Kavitha Yaddanapudi, Chi Li
Sci Rep. 2023; 13: 9929. Published online 2023 Jun 19. doi: 10.1038/s41598-023-37146-5
PMCID:
PMC10279720
AbstractArticlePDF–10M
3.
Capsazepine (CPZ) Inhibits TRPC6 Conductance and Is Protective in Adriamycin-Induced Nephropathy and Diabetic Glomerulopathy
Henning Hagmann, Naghmeh Hassanzadeh Khayyat, Mahsa Matin, Cem Oezel, He Chen, Astrid Schauss, Christoph Schell, Thomas Benzing, Stuart Dryer, Paul T. Brinkkoetter
Cells. 2023 Jan; 12(2): 271. Published online 2023 Jan 10. doi: 10.3390/cells12020271
PMCID:
PMC9856956
AbstractArticlePDF–3.8M
4.
Paraoxonase 2 (PON2) Deficiency Reproduces Lipid Alterations of Diabetic and Inflammatory Glomerular Disease and Affects TRPC6 Signaling
Henning Hagmann, Naghmeh Hassanzadeh Khayyat, Cem Oezel, Antonios Papadakis, Alexander Kuczkowski, Thomas Benzing, Erich Gulbins, Stuart Dryer, Paul T. Brinkkoetter
Cells. 2022 Nov; 11(22): 3625. Published online 2022 Nov 16. doi: 10.3390/cells11223625
PMCID:
PMC9688324
AbstractArticlePDF–2.7M
5.
Examining the role of paraoxonase 2 in the dopaminergic system of the mouse brain
Jacqueline M. Garrick, Khoi Dao, Lucio G. Costa, Judit Marsillach, Clement E. Furlong
BMC Neurosci. 2022; 23: 52. Published online 2022 Sep 2. doi: 10.1186/s12868-022-00738-4
PMCID:
PMC9438175
AbstractArticlePDF–1.6M
6.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
7.
Paraoxonase 2 is an ER chaperone that regulates the epithelial Na+ channel
Shujie Shi, Teresa M. Buck, Andrew J. Nickerson, Jeffrey L. Brodsky, Thomas R. Kleyman
Am J Physiol Cell Physiol. 2022 Jan 1; 322(1): C111–C121. Published online 2021 Dec 1. doi: 10.1152/ajpcell.00335.2021
PMCID:
PMC8759969
AbstractArticle
8.
Paraoxonase 2 Deficiency in Mice Alters Motor Behavior and Causes Region-Specific Transcript Changes in the Brain
Jacqueline M. Garrick, Toby B. Cole, Theo K. Bammler, James W. MacDonald, Judit Marsillach, Clement E. Furlong, Lucio G. Costa
Neurotoxicol Teratol. Author manuscript; available in PMC 2022 Sep 1.
Published in final edited form as: Neurotoxicol Teratol. 2021 Sep-Oct; 87: 107010. Published online 2021 Jul 1. doi: 10.1016/j.ntt.2021.107010
PMCID:
PMC8440460
AbstractArticlePDF–2.3M
9.
Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis
Lisa Spiecker, Ines Witte, Julia Mehlig, Viral Shah, Markus Meyerhöfer, Patricia S. Haehnel, Victoria Petermann, Andrea Schüler, Piyush More, Nina Cabezas-Wallscheid, Sven Horke, Andrea Pautz, Andreas Daiber, Daniel Sasca, Thomas Kindler, Hartmut Kleinert
Oxid Med Cell Longev. 2021; 2021: 3917028. Published online 2021 Jun 25. doi: 10.1155/2021/3917028
PMCID:
PMC8253644
AbstractArticlePDF–2.6M
10.
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis
Lili Pan, Chao Hong, Lai N. Chan, Gang Xiao, Parmanand Malvi, Mark E. Robinson, Huimin Geng, Srinivasa T. Reddy, Jaewoong Lee, Vishal Khairnar, Kadriye Nehir Cosgun, Liang Xu, Kohei Kume, Teresa Sadras, Shaoyuan Wang, Narendra Wajapeyee, Markus Müschen
Proc Natl Acad Sci U S A. 2021 Feb 16; 118(7): e2016553118. Published online 2021 Feb 2. doi: 10.1073/pnas.2016553118
PMCID:
PMC7896313
AbstractArticlePDF–2.6M
11.
Myeloid cell-synthesized coagulation Factor X dampens anti-tumor immunity
Claudine Graf, Petra Wilgenbus, Sven Pagel, Jennifer Pott, Federico Marini, Sabine Reyda, Maki Kitano, Stephan Macher-Göppinger, Hartmut Weiler, Wolfram Ruf
Sci Immunol. Author manuscript; available in PMC 2020 Mar 20.
Published in final edited form as: Sci Immunol. 2019 Sep 20; 4(39): eaaw8405. doi: 10.1126/sciimmunol.aaw8405
PMCID:
PMC6830514
AbstractArticlePDF–3.4M
12.
Paraoxonase 2 Prevents the Development of Heart Failure
Wei Li, David Kennedy, Zhili Shao, Xi Wang, Andre Klaassen Kamdar, Malory Weber, Kayla Mislick, Kathryn Kiefer, Rommel Morales, Brendan Agatisa-Boyle, Diana M. Shih, Srinivasa T. Reddy, Christine S. Moravec, W. H. Wilson Tang
Free Radic Biol Med. Author manuscript; available in PMC 2019 Jun 1.
Published in final edited form as: Free Radic Biol Med. 2018 Jun; 121: 117–126. Published online 2018 May 2. doi: 10.1016/j.freeradbiomed.2018.04.583
PMCID:
PMC5971153
AbstractArticlePDF–777K
13.
Regulation of the epithelial Na+ channel by paraoxonase-2
Shujie Shi, Teresa M. Buck, Carol L. Kinlough, Allison L. Marciszyn, Rebecca P. Hughey, Martin Chalfie, Jeffrey L. Brodsky, Thomas R. Kleyman
J Biol Chem. 2017 Sep 22; 292(38): 15927–15938. Published online 2017 Aug 2. doi: 10.1074/jbc.M117.785253
PMCID:
PMC5612122
AbstractArticlePDF–2.1M
14.
Paraoxonase 2 Serves a Proapopotic Function in Mouse and Human Cells in Response to the Pseudomonas aeruginosa Quorum-sensing Molecule N-(3-Oxododecanoyl)-homoserine Lactone
Christian Schwarzer, Zhu Fu, Takeshi Morita, Aaron G. Whitt, Aaron M. Neely, Chi Li, Terry E. Machen
J Biol Chem. 2015 Mar 13; 290(11): 7247–7258. Published online 2015 Jan 27. doi: 10.1074/jbc.M114.620039
PMCID:
PMC4358143
AbstractArticlePDF–2.2M
15.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
16.
Role of PON2 in innate immune response in an acute infection model
Asokan Devarajan, Noam Bourquard, Victor R Grijalva, Feng Gao, Ekambaram Ganapathy, Jitendra Verma, Srinivasa T. Reddy
Mol Genet Metab. Author manuscript; available in PMC 2014 Nov 1.
Published in final edited form as: Mol Genet Metab. 2013 Nov; 110(3): 362–370. Published online 2013 Jul 15. doi: 10.1016/j.ymgme.2013.07.003
PMCID:
PMC3800229
AbstractArticlePDF–1.3M
17.
Impaired hepatic insulin signalling in PON2-deficient mice: a novel role for the PON2/apoE axis on the macrophage inflammatory response
Noam Bourquard, Carey J. Ng, Srinivasa T. Reddy
Biochem J. Author manuscript; available in PMC 2013 Aug 14.
Published in final edited form as: Biochem J. 2011 May 15; 436(1): 91–100. doi: 10.1042/BJ20101891
PMCID:
PMC3743554
AbstractArticlePDF–3.2M
18.
GENDER DIFFERENCES IN BRAIN SUSCEPTIBILITY TO OXIDATIVE STRESS ARE MEDIATED BY LEVELS OF PARAOXONASE-2 (PON2) EXPRESSION
G. Giordano, L. Tait, C.E. Furlong, T.B. Cole, T.J. Kavanagh, L.G. Costa
Free Radic Biol Med. Author manuscript; available in PMC 2014 May 1.
Published in final edited form as: Free Radic Biol Med. 2013 May; 58: 98–108. Published online 2013 Jan 30. doi: 10.1016/j.freeradbiomed.2013.01.019
PMCID:
PMC3622778
AbstractArticlePDF–2.2M
19.
Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth
K. P. Himes, E. Koppes, J. Richard Chaillet
Dev Biol. Author manuscript; available in PMC 2014 Jan 1.
Published in final edited form as: Dev Biol. 2013 Jan 1; 373(1): 72–82. Published online 2012 Oct 17. doi: 10.1016/j.ydbio.2012.10.010
PMCID:
PMC3508140
AbstractArticlePDF–7.3M
20.
Expression at the Imprinted Dlk1-Gtl2 Locus Is Regulated by Proneural Genes in the Developing Telencephalon
Julie Seibt, Olivier Armant, Anne Le Digarcher, Diogo Castro, Vidya Ramesh, Laurent Journot, François Guillemot, Pierre Vanderhaeghen, Tristan Bouschet
PLoS One. 2012; 7(11): e48675. Published online 2012 Nov 6. doi: 10.1371/journal.pone.0048675
PMCID:
PMC3490856
AbstractArticlePDF–4.1M

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