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Select item 110191281.

Mitochondrial S‐adenosylmethionine deficiency induces mitochondrial unfolded protein response and extends lifespan in Caenorhabditis elegans

Tse Yu Chen, Feng‐Yung Wang, Pin‐Jung Lee, Ao‐Lin Hsu, Tsui‐Ting Ching

Aging Cell. 2024 Apr; 23(4): e14103. Published online 2024 Feb 15. doi: 10.1111/acel.14103

PMCID:: PMC11019128

Abstract Article PDF–4.7M

Select item 109882892.

SAMS-1 is required for the normal defecation motor program in Caenorhabditis elegans

Keiko Hirota, Masato Matsuoka

MicroPubl Biol. 2024; 2024: 10.17912/micropub.biology.001101. Published online 2024 Mar 19. doi: 10.17912/micropub.biology.001101

PMCID:: PMC10988289

Abstract Article PDF–1.7M

Select item 109147813.

Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B

Misaki Okahata, Natsumi Sawada, Kenji Nakao, Akane Ohta, Atsushi Kuhara

Sci Rep. 2024; 14: 5401. Published online 2024 Mar 5. doi: 10.1038/s41598-024-55794-z

PMCID:: PMC10914781

Abstract Article PDF–2.1M

Select item 107611214.

CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing

Doreen I. Lugano, Lindsey N. Barrett, Dale Chaput, Margaret A. Park, Sandy D. Westerheide

RNA Biol. 2024; 21(1): 1–11. Published online 2023 Dec 21. doi: 10.1080/15476286.2023.2289707

PMCID:: PMC10761121

Abstract Article PDF–2.5M

Select item 101591685.

Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain

Faruk Dube, Andrea Hinas, Nicolas Delhomme, Magnus Åbrink, Staffan Svärd, Eva Tydén

PLoS One. 2023; 18(5): e0285262. Published online 2023 May 4. doi: 10.1371/journal.pone.0285262

PMCID:: PMC10159168

Abstract Article PDF–1.9M

Select item 99841916.

S-adenosylmethionine synthases specify distinct H3K4me3 populations and gene expression patterns during heat stress

Adwait A Godbole, Sneha Gopalan, Thien-Kim Nguyen, Alexander L Munden, Dominique S Lui, Matthew J Fanelli, Paula Vo, Caroline A Lewis, Jessica B Spinelli, Thomas G Fazzio, Amy K Walker

eLife. 2023; 12: e79511. Published online 2023 Feb 9. doi: 10.7554/eLife.79511

PMCID:: PMC9984191

Abstract Article PDF–2.6M

Select item 98949357.

FMO rewires metabolism to promote longevity through tryptophan and one carbon metabolism in C. elegans

Hyo Sub Choi, Ajay Bhat, Marshall B. Howington, Megan L. Schaller, Rebecca L. Cox, Shijiao Huang, Safa Beydoun, Hillary A. Miller, Angela M. Tuckowski, Joy Mecano, Elizabeth S. Dean, Lindy Jensen, Daniel A. Beard, Charles R. Evans, Scott F. Leiser

Nat Commun. 2023; 14: 562. Published online 2023 Feb 2. doi: 10.1038/s41467-023-36181-0

PMCID:: PMC9894935

Abstract Article PDF–3.1M

Select item 98099488.

SAMS-1 coordinates HLH-30/TFEB and PHA-4/FOXA activities through histone methylation to mediate dietary restriction-induced autophagy and longevity

Chiao-Yin Lim, Huan-Ting Lin, Caroline Kumsta, Tzu-Chiao Lu, Feng-Yung Wang, Yun-Hsuan Kang, Malene Hansen, Tsui-Ting Ching, Ao-Lin Hsu

Autophagy. 2023; 19(1): 224–240. Published online 2022 May 3. doi: 10.1080/15548627.2022.2068267

PMCID:: PMC9809948

Abstract Article PDF–4.7M

Select item 97499069.

2-hydroxyisobutyric acid (2-HIBA) modulates ageing and fat deposition in Caenorhabditis elegans

Emily Schifano, Giorgia Conta, Adele Preziosi, Carino Ferrante, Giovanni Batignani, Patrizia Mancini, Alberta Tomassini, Fabio Sciubba, Tullio Scopigno, Daniela Uccelletti, Alfredo Miccheli

Front Mol Biosci. 2022; 9: 986022. Published online 2022 Nov 23. doi: 10.3389/fmolb.2022.986022

PMCID:: PMC9749906

Abstract Article PDF–3.1M

Select item 966884310.

Sulfur amino acid supplementation displays therapeutic potential in a C. elegans model of Duchenne muscular dystrophy

Rebecca A. Ellwood, Luke Slade, Jonathan Lewis, Roberta Torregrossa, Surabhi Sudevan, Mathew Piasecki, Matthew Whiteman, Timothy Etheridge, Nathaniel J. Szewczyk

Commun Biol. 2022; 5: 1255. Published online 2022 Nov 16. doi: 10.1038/s42003-022-04212-z

PMCID:: PMC9668843

Abstract Article PDF–3.4M

Select item 964974711.

A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience

Changnan Wang, Bingying Wang, Taruna Pandey, Yong Long, Jianxiu Zhang, Fiona Oh, Jessica Sima, Ruyin Guo, Yun Liu, Chao Zhang, Shaeri Mukherjee, Michael Bassik, Weichun Lin, Huichao Deng, Goncalo Vale, Jeffrey G. McDonald, Kang Shen, Dengke K. Ma

Nat Commun. 2022; 13: 6805. Published online 2022 Nov 10. doi: 10.1038/s41467-022-34450-y

PMCID:: PMC9649747

Abstract Article PDF–3.6M

Select item 943784812.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 909032613.

Dithiothreitol causes toxicity in C. elegans by modulating the methionine–homocysteine cycle

Gokul G, Jogender Singh

eLife. 2022; 11: e76021. Published online 2022 Apr 19. doi: 10.7554/eLife.76021

PMCID:: PMC9090326

Abstract Article PDF–15M

Select item 902071614.

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

Elisabeth Holzer, Cornelia Rumpf-Kienzl, Sebastian Falk, Alexander Dammermann

PLoS Genet. 2022 Apr; 18(4): e1010150. Published online 2022 Apr 20. doi: 10.1371/journal.pgen.1010150

Correction in:: PLoS Genet. 2023 Feb; 19(2): e1010645.

PMCID:: PMC9020716

Abstract Article PDF–2.0M

Select item 881402615.

Mitochondrial protein import determines lifespan through metabolic reprogramming and de novo serine biosynthesis

Eirini Lionaki, Ilias Gkikas, Ioanna Daskalaki, Maria-Konstantina Ioannidi, Maria I. Klapa, Nektarios Tavernarakis

Nat Commun. 2022; 13: 651. Published online 2022 Feb 3. doi: 10.1038/s41467-022-28272-1

PMCID:: PMC8814026

Abstract Article PDF–2.3M

Select item 875312216.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 844679317.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 833118318.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 826306619.

Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences

Xing Zhang, Benjamin W. Harding, Dina Aggad, Damien Courtine, Jia-Xuan Chen, Nathalie Pujol, Jonathan J. Ewbank

PLoS Genet. 2021 Jun; 17(6): e1009600. Published online 2021 Jun 24. doi: 10.1371/journal.pgen.1009600

PMCID:: PMC8263066

Abstract Article PDF–5.0M

Select item 799517620.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4