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Select item 104741141.

Inhibiting the cytosolic function of CXXC5 accelerates diabetic wound healing by enhancing angiogenesis and skin repair

Eunhwan Kim, Seol Hwa Seo, Yumi Hwang, Yeong Chan Ryu, Heejene Kim, Kyoung-Mi Lee, Jin Woo Lee, Kwang Hwan Park, Kang-Yell Choi

Exp Mol Med. 2023 Aug; 55(8): 1770–1782. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01064-3

PMCID:: PMC10474114

Abstract Article PDF–7.3M

Select item 99546852.

CXXC5 Mediates DHT-Induced Androgenetic Alopecia via PGD₂

Yeong Chan Ryu, Jiyeon Park, You-Rin Kim, Sehee Choi, Geon-Uk Kim, Eunhwan Kim, Yumi Hwang, Heejene Kim, Gyoonhee Han, Soung-Hoon Lee, Kang-Yell Choi

Cells. 2023 Feb; 12(4): 555. Published online 2023 Feb 9. doi: 10.3390/cells12040555

PMCID:: PMC9954685

Abstract Article PDF–4.0M

Select item 98605003.

Zinc-finger protein CXXC5 promotes breast carcinogenesis by regulating the TSC1/mTOR signaling pathway

Wenjuan Wang, Zhaohan Zhang, Minghui Zhao, Yu Wang, Yuze Ge, Lin Shan

J Biol Chem. 2023 Jan; 299(1): 102812. Published online 2022 Dec 17. doi: 10.1016/j.jbc.2022.102812

PMCID:: PMC9860500

Abstract Article PDF–5.8M

Select item 93485764.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 89825075.

Inhibition of CXXC5 function reverses obesity‐related metabolic diseases

Seol Hwa Seo, Eunhwan Kim, Soung‐Hoon Lee, Yong‐ho Lee, Dai Hoon Han, Hyesun Go, Je Kyung Seong, Kang‐Yell Choi

Clin Transl Med. 2022 Apr; 12(4): e742. Published online 2022 Apr 5. doi: 10.1002/ctm2.742

PMCID:: PMC8982507

Abstract Article PDF–7.7M

Select item 87190996.

The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cell expansion

Audrey Astori, Gabriel Matherat, Isabelle Munoz, Emilie-Fleur Gautier, Didier Surdez, Yaël Zermati, Frédérique Verdier, Sakina Zaidi, Vincent Feuillet, Amir Kadi, Evelyne Lauret, Olivier Delattre, Carine Lefèvre, Michaela Fontenay, Evelyne Ségal-Bendirdjian, Isabelle Dusanter-Fourt, Didier Bouscary, Olivier Hermine, Patrick Mayeux, Frédéric Pendino

Haematologica. 2022 Jan 1; 107(1): 268–283. Published online 2020 Nov 26. doi: 10.3324/haematol.2020.263558

PMCID:: PMC8719099

Abstract Article PDF–2.5M

Select item 84133307.

A prelude to the proximity interaction mapping of CXXC5

Gamze Ayaz, Gizem Turan, Çağla Ece Olgun, Gizem Kars, Burcu Karakaya, Kerim Yavuz, Öykü Deniz Demiralay, Tolga Can, Mesut Muyan, Pelin Yaşar

Sci Rep. 2021; 11: 17587. Published online 2021 Sep 2. doi: 10.1038/s41598-021-97060-6

PMCID:: PMC8413330

Abstract Article PDF–3.7M

Select item 67468228.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 64588509.

CXXC5 mediates growth plate senescence and is a target for enhancement of longitudinal bone growth

Sehee Choi, Hyun-Yi Kim, Pu-Hyeon Cha, Seol Hwa Seo, Chulho Lee, Yejoo Choi, Wookjin Shin, Yunseok Heo, Gyoonhee Han, Weontae Lee, Kang-Yell Choi

Life Sci Alliance. 2019 Apr; 2(2): e201800254. Published online 2019 Apr 10. doi: 10.26508/lsa.201800254

PMCID:: PMC6458850

Abstract Article PDF–2.9M

Select item 642009710.

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination in sister chromatids

Kyosuke Nakamura, Giulia Saredi, Jordan R. Becker, Benjamin M. Foster, Nhuong V. Nguyen, Tracey Beyer, Laura C. Cesa, Peter A. Faull, Saulius Lukauskas, Thomas Frimurer, J. Ross Chapman, Till Bartke, Anja Groth

Nat Cell Biol. Author manuscript; available in PMC 2019 Aug 25.

Published in final edited form as: Nat Cell Biol. 2019 Mar; 21(3): 311–318. Published online 2019 Feb 25. doi: 10.1038/s41556-019-0282-9

PMCID:: PMC6420097

Article PDF–1.7M

Select item 634919711.

CXXC5: A novel regulator and coordinator of TGF‐β, BMP and Wnt signaling

Xiangyang Xiong, Shuo Tu, Jianbin Wang, Shiwen Luo, Xiaohua Yan

J Cell Mol Med. 2019 Feb; 23(2): 740–749. Published online 2018 Nov 27. doi: 10.1111/jcmm.14046

PMCID:: PMC6349197

Abstract Article PDF–427K

Select item 549522512.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 522031413.

KANK1 inhibits cell growth by inducing apoptosis though regulating CXXC5 in human malignant peripheral nerve sheath tumors

Zhibin Cui, Yingjia Shen, Kenny H. Chen, Suresh K. Mittal, Jer-Yen Yang, GuangJun Zhang

Sci Rep. 2017; 7: 40325. Published online 2017 Jan 9. doi: 10.1038/srep40325

Correction in:: Sci Rep. 2017; 7: 46392.

PMCID:: PMC5220314

Abstract Article PDF–1.9M

Select item 512289614.

Estradiol-Estrogen Receptor α Mediates the Expression of the CXXC5 Gene through the Estrogen Response Element-Dependent Signaling Pathway

Pelin Yaşar, Gamze Ayaz, Mesut Muyan

Sci Rep. 2016; 6: 37808. Published online 2016 Nov 25. doi: 10.1038/srep37808

PMCID:: PMC5122896

Abstract Article PDF–1.2M

Select item 449341115.

The Dishevelled-binding protein CXXC5 negatively regulates cutaneous wound healing

Soung-Hoon Lee, Mi-Yeon Kim, Hyun-Yi Kim, Young-Mi Lee, Heesu Kim, Kyoung Ae Nam, Mi Ryung Roh, Do Sik Min, Kee Yang Chung, Kang-Yell Choi

J Exp Med. 2015 Jun 29; 212(7): 1061–1080. doi: 10.1084/jem.20141601

PMCID:: PMC4493411

Abstract Article PDF–6.7M

Select item 446380916.

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

Andrea Kühnl, Peter J. M. Valk, Mathijs A. Sanders, Adam Ivey, Robert K. Hills, Ken I. Mills, Rosemary E. Gale, Martin F. Kaiser, Richard Dillon, Melanie Joannides, Amanda Gilkes, Torsten Haferlach, Susanne Schnittger, Estelle Duprez, David C. Linch, Ruud Delwel, Bob Löwenberg, Claudia D. Baldus, Ellen Solomon, Alan K. Burnett, David Grimwade

Blood. 2015 May 7; 125(19): 2985–2994. Prepublished online 2015 Mar 24. doi: 10.1182/blood-2014-12-613703

PMCID:: PMC4463809

Abstract Article

Select item 441361817.

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation

Øystein Bruserud, Håkon Reikvam, Hanne Fredly, Jørn Skavland, Karen-Marie Hagen, Tuyen Thy van Hoang, Annette K. Brenner, Amir Kadi, Audrey Astori, Bjørn Tore Gjertsen, Frederic Pendino

Oncotarget. 2015 Feb; 6(5): 2794–2811. Published online 2014 Dec 26. doi: 10.18632/oncotarget.3056

PMCID:: PMC4413618

Abstract Article PDF–1.3M

Select item 382454118.

CXXC5 (Retinoid-Inducible Nuclear Factor, RINF) is a Potential Therapeutic Target in High-Risk Human Acute Myeloid Leukemia

Audrey Astori, Hanne Fredly, Thomas Aquinas Aloysius, Lars Bullinger, Véronique Mansat-De Mas, Pierre de la Grange, François Delhommeau, Karen Marie Hagen, Christian Récher, Isabelle Dusanter-Fourt, Stian Knappskog, Johan Richard Lillehaug, Frédéric Pendino, Øystein Bruserudg

Oncotarget. 2013 Sep; 4(9): 1438–1448. Published online 2013 Aug 15. doi: 10.18632/oncotarget.1195

PMCID:: PMC3824541

Abstract Article PDF–852K

Select item 357582219.

Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2

Siddhesh Aras, Oleg Pak, Natascha Sommer, Russell Finley, Jr, Maik Hüttemann, Norbert Weissmann, Lawrence I. Grossman

Nucleic Acids Res. 2013 Feb; 41(4): 2255–2266. Published online 2013 Jan 8. doi: 10.1093/nar/gks1454

PMCID:: PMC3575822

Abstract Article PDF–4.7M

Select item 326170820.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

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