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Items: 1 to 20 of 1249

1.
Sinomenine Ameliorated Microglial Activation and Neuropathic Pain After Chronic Constriction Injury Via TGF‐β1/ALK5/Smad3 Signalling Pathway
Ling Ling, Min Luo, Haolin Yin, Yunyun Tian, Tao Wang, Bangjian Zhang, Li Yin, Yuehui Zhang, Jiang Bian
J Cell Mol Med. 2024 Nov; 28(22): e70214. Published online 2024 Nov 25. doi: 10.1111/jcmm.70214
PMCID:
PMC11588427
AbstractArticlePDF–19M
2.
Single-cell RNA transcriptomics in mice reveals embryonic origin of fibrosis due to maternal obesity
Md Nazmul Hossain, Yao Gao, Xinrui Li, Liang Zhao, Xiangdong Liu, Jeanene Marie de Avila, Mei-Jun Zhu, Min Du
eBioMedicine. 2024 Nov; 109: 105421. Published online 2024 Oct 30. doi: 10.1016/j.ebiom.2024.105421
PMCID:
PMC11565040
AbstractArticlePDF–4.9M
3.
Reply to Chong et al.: Investigating TGFβ1 biological activities using genetically engineered mouse strains
Dennis R. Riehl, Arjun Sharma, Julian Roewe, Christoph Reinhardt, Katrin Schäfer, Markus Bosmann
Proc Natl Acad Sci U S A. 2024 Oct 29; 121(44): e2408647121. Published online 2024 Oct 18. doi: 10.1073/pnas.2408647121
PMCID:
PMC11536109
ArticlePDF–152K
4.
Dynamic allostery drives autocrine and paracrine TGF-β signaling
Mingliang Jin, Robert I. Seed, Guoqing Cai, Tiffany Shing, Li Wang, Saburo Ito, Anthony Cormier, Stephanie A. Wankowicz, Jillian M. Jespersen, Jody L. Baron, Nicholas D. Carey, Melody G. Campbell, Zanlin Yu, Phu K. Tang, Pilar Cossio, Weihua Wen, Jianlong Lou, James Marks, Stephen L. Nishimura, Yifan Cheng
Cell. Author manuscript; available in PMC 2024 Nov 3.
Published in final edited form as: Cell. 2024 Oct 31; 187(22): 6200–6219.e23. Published online 2024 Sep 16. doi: 10.1016/j.cell.2024.08.036
PMCID:
PMC11531391
AbstractArticlePDF–3.7M
5.
Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation
Vaishali N. Patel, Marit H. Aure, Sophie H. Choi, James R. Ball, Ethan D. Lane, Zhangjie Wang, Yongmei Xu, Changyu Zheng, Xibao Liu, Daniel Martin, Jillian Y. Pailin, Michaela Prochazkova, Ashok B. Kulkarni, Toin H. van Kuppevelt, Indu S. Ambudkar, Jian Liu, Matthew P. Hoffman
Nat Commun. 2024; 15: 7584. Published online 2024 Aug 31. doi: 10.1038/s41467-024-51862-0
Correction in:
Nat Commun. 2024; 15: 8784.
PMCID:
PMC11365954
AbstractArticlePDF–5.0M
6.
Upregulation of Metrnl improves diabetic kidney disease by inhibiting the TGF-β1/Smads signaling pathway: A potential therapeutic target
Lu Lin, Shulin Huang, Xin Lin, Xiaoling Liu, Xiangjin Xu, Chunmei Li, Pin Chen
PLoS One. 2024; 19(8): e0309338. Published online 2024 Aug 27. doi: 10.1371/journal.pone.0309338
PMCID:
PMC11349091
AbstractArticlePDF–4.3M
7.
ISG15 accelerates acute kidney injury and the subsequent AKI-to-CKD transition by promoting TGFβR1 ISGylation
Na Cui, Chengyu Liu, Xiang Tang, Liangliang Song, Zixuan Xiao, Chen Wang, Yancai Wu, Yihao Zhou, Chentai Peng, Yuxia Liu, Ling Zheng, Xinran Liu, Kun Huang, Hong Chen
Theranostics. 2024; 14(11): 4536–4553. Published online 2024 Jul 22. doi: 10.7150/thno.95796
PMCID:
PMC11303071
AbstractArticlePDF–15M
8.
Impaired Reciprocal Regulation between SIRT6 and TGF-β Signaling in Fatty Liver
Xiyan Xiang, Kazufumi Ohshiro, Sobia Zaidi, Xiaochun Yang, Krishanu Bhowmick, Anil K. Vegesna, David Bernstein, James M Crawford, Bibhuti Mishra, Patricia S. Latham, Nancy R. Gough, Shuyun Rao, Lopa Mishra
FASEB J. Author manuscript; available in PMC 2024 Jul 30.
Published in final edited form as: FASEB J. 2022 Jun; 36(6): e22335. doi: 10.1096/fj.202101518R
PMCID:
PMC11288617
AbstractArticlePDF–1.6M
9.
ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death
Jing Yang, Ya-Nan Zhang, Ren-Xue Wang, Chen-Zhi Hao, Yiling Qiu, Hao Chi, Wei-Sha Luan, HongYi Tang, Xiu-Juan Zhang, XuXu Sun, Jonathan A Sheps, Victor Ling, Muqing Cao, Jian-she Wang
J Med Genet. 2024 Aug; 61(8): 750–758. Published online 2024 May 30. doi: 10.1136/jmg-2023-109779
PMCID:
PMC11287636
AbstractArticlePDF–6.1M
10.
Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice
Alicia Bedolla, Elliot Wegman, Max Weed, Messiyah K. Stevens, Kierra Ware, Aditi Paranjpe, Anastasia Alkhimovitch, Igal Ifergan, Aleksandr Taranov, Joshua D. Peter, Rosa Maria Salazar Gonzalez, J. Elliott Robinson, Lucas McClain, Krishna M. Roskin, Nigel H. Greig, Yu Luo
Nat Commun. 2024; 15: 5306. Published online 2024 Jun 21. doi: 10.1038/s41467-024-49596-0
PMCID:
PMC11192737
AbstractArticlePDF–19M
11.
Monocyte chemoattractant protein‐1 is generated via TGF‐β by myofibroblasts in gastric intestinal metaplasia and carcinoma without H. pylori infection
Hiroyuki Mutoh, Miho Sashikawa, Hiroko Hayakawa, Kentaro Sugano
Cancer Sci. 2010 Aug; 101(8): 1783–1789. Published online 2010 Apr 29. doi: 10.1111/j.1349-7006.2010.01609.x
PMCID:
PMC11158495
AbstractArticlePDF–783K
12.
Gene silencing of TGF-β1 enhances antitumor immunity induced with a dendritic cell vaccine by reducing tumor-associated regulatory T cells
Helen Conroy, Karen C. Galvin, Sarah C. Higgins, Kingston H. G. Mills
Cancer Immunol Immunother. 2012 Mar; 61(3): 425–431. Published online 2011 Dec 23. doi: 10.1007/s00262-011-1188-y
PMCID:
PMC11029020
AbstractArticlePDF–391K
13.
The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance
Justin P. Edwards, Timothy W. Hand, Denise Morais da Fonseca, Deborah D. Glass, Yasmine Belkaid, Ethan M. Shevach
Eur J Immunol. Author manuscript; available in PMC 2024 Apr 17.
Published in final edited form as: Eur J Immunol. 2016 Jun; 46(6): 1480–1489. Published online 2016 Apr 23. doi: 10.1002/eji.201546204
PMCID:
PMC11022272
AbstractArticlePDF–1.9M
14.
Chk2 Modulates Bmi1-Deficiency-Induced Renal Aging and Fibrosis via Oxidative Stress, DNA Damage, and p53/TGFβ1-Induced Epithelial-Mesenchymal Transition
Jinhong Lu, Weiwei Sun, Boyang Liu, Jinge Zhang, Rong Wang, David Goltzman, Dengshun Miao
Int J Biol Sci. 2024; 20(6): 2008–2026. Published online 2024 Mar 11. doi: 10.7150/ijbs.93598
PMCID:
PMC11008269
AbstractArticlePDF–17M
15.
TGF-β controls alveolar type 1 epithelial cell plasticity and alveolar matrisome gene transcription in mice
Danielle A. Callaway, Ian J. Penkala, Su Zhou, Jonathan J. Knowlton, Fabian Cardenas-Diaz, Apoorva Babu, Michael P. Morley, Mariana Lopes, Benjamin A. Garcia, Edward E. Morrisey
J Clin Invest. 2024 Mar 15; 134(6): e172095. Published online 2024 Mar 15. doi: 10.1172/JCI172095
PMCID:
PMC10947970
AbstractArticlePDF–24M
16.
Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity
Jong-Uk Lee, Ki Sung Song, Jisu Hong, Hyesun Shin, Eunji Park, Junyeong Baek, Shinhee Park, Ae-Rin Baek, Junehyuk Lee, An Soo Jang, Do Jin Kim, Su Sie Chin, U-Jin Kim, Sung Hwan Jeong, Sung-Woo Park
Exp Mol Med. 2024 Feb; 56(2): 478–490. Published online 2024 Feb 28. doi: 10.1038/s12276-024-01170-w
PMCID:
PMC10907606
AbstractArticlePDF–3.2M
17.
HER2 phosphorylation induced by TGF-β promotes mammary morphogenesis and breast cancer progression
Qiaoni Shi, Fei Huang, Yalong Wang, Huidong Liu, Haiteng Deng, Ye-Guang Chen
J Cell Biol. 2024 Apr 1; 223(4): e202307138. Published online 2024 Feb 26. doi: 10.1083/jcb.202307138
PMCID:
PMC10896696
AbstractArticlePDF–7.8M
18.
FOXS1 is increased in liver fibrosis and regulates TGFβ responsiveness and proliferation pathways in human hepatic stellate cells
Evelyn A. Bates, Zachary A. Kipp, Wang-Hsin Lee, Genesee J. Martinez, Lauren Weaver, Kathryn N. Becker, Sally N. Pauss, Justin F. Creeden, Garrett B. Anspach, Robert N. Helsley, Mei Xu, Maria E.C. Bruno, Marlene E. Starr, Terry D. Hinds, Jr.
J Biol Chem. 2024 Mar; 300(3): 105691. Published online 2024 Jan 26. doi: 10.1016/j.jbc.2024.105691
PMCID:
PMC10878791
AbstractArticlePDF–6.4M
19.
A comparative evaluation of the strengths and potential caveats of the microglial inducible CreER mouse models
Alicia M. Bedolla, Gabriel L. McKinsey, Kierra Ware, Nicolas Santander, Thomas D. Arnold, Yu Luo
Cell Rep. Author manuscript; available in PMC 2024 Feb 18.
Published in final edited form as: Cell Rep. 2024 Jan 23; 43(1): 113660. Published online 2024 Jan 12. doi: 10.1016/j.celrep.2023.113660
PMCID:
PMC10874587
AbstractArticlePDF–3.5M
20.
Periostin–TGF-β feedforward loop contributes to tumour-stroma crosstalk in liver metastatic outgrowth of colorectal cancer
Bin Liu, Tiantian Wu, Biyu Lin, Xingxing Liu, Yingfu Liu, Gang Song, Chuannan Fan, Gaoliang Ouyang
Br J Cancer. 2024 Feb 24; 130(3): 358–368. Published online 2023 Dec 14. doi: 10.1038/s41416-023-02516-3
PMCID:
PMC10844286
AbstractArticlePDF–13M

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