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Select item 108029521.

Characterization of the intracellular neurexin interactome by in vivo proximity ligation suggests its involvement in presynaptic actin assembly

Marcos Schaan Profes, Araven Tiroumalechetty, Neel Patel, Stephanie S. Lauar, Simone Sidoli, Peri T. Kurshan

PLoS Biol. 2024 Jan; 22(1): e3002466. Published online 2024 Jan 22. doi: 10.1371/journal.pbio.3002466

PMCID:: PMC10802952

Abstract Article PDF–2.7M

Select item 107609722.

PP2A inhibition causes synthetic lethality in BRCA2-mutated prostate cancer models via spindle assembly checkpoint reactivation

Jian Wang, Yuke Chen, Shiwei Li, Wanchang Liu, Xiao Albert Zhou, Yefei Luo, Zhanzhan Xu, Yundong Xiong, Kaiqi Cheng, Mingjian Ruan, Wei Yu, Xiaoman Li, Weibin Wang, Jiadong Wang

J Clin Invest. 2024 Jan 2; 134(1): e172137. Published online 2024 Jan 2. doi: 10.1172/JCI172137

PMCID:: PMC10760972

Abstract Article PDF–15M

Select item 106589133.

THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans

Angelina Zheleva, Lola P. Camino, Nuria Fernández-Fernández, María García-Rubio, Peter Askjaer, Tatiana García-Muse, Andrés Aguilera

J Cell Sci. 2021 Oct 15; 134(20): jcs258435. Published online 2021 Oct 22. doi: 10.1242/jcs.258435

PMCID:: PMC10658913

Abstract Article

Select item 106176264.

SIN-3 acts in distinct complexes to regulate the germline transcriptional program in Caenorhabditis elegans

Valerie J. Robert, Matthieu Caron, Loic Gely, Annie Adrait, Victoria Pakulska, Yohann Couté, Manon Chevalier, Christian G. Riedel, Cecile Bedet, Francesca Palladino

Development. 2023 Nov 1; 150(21): dev201755. Published online 2023 Oct 17. doi: 10.1242/dev.201755

PMCID:: PMC10617626

Abstract Article

Select item 105166705.

Disparate roles for C. elegans DNA translocase paralogs RAD-54.L and RAD-54.B in meiotic prophase germ cells

Kei Yamaya, Bin Wang, Nadin Memar, Arome Solomon Odiba, Alexander Woglar, Anton Gartner, Anne M Villeneuve

Nucleic Acids Res. 2023 Sep 22; 51(17): 9183–9202. Published online 2023 Aug 7. doi: 10.1093/nar/gkad638

PMCID:: PMC10516670

Abstract Article PDF–3.7M

Select item 101131586.

ATM signaling modulates cohesin behavior in meiotic prophase and proliferating cells

Zhouliang Yu, Hyung Jun Kim, Abby F. Dernburg

Nat Struct Mol Biol. 2023; 30(4): 436–450. Published online 2023 Mar 6. doi: 10.1038/s41594-023-00929-5

PMCID:: PMC10113158

Abstract Article PDF–19M

Select item 101131567.

The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities

Arturo Bujarrabal-Dueso, Georg Sendtner, David H. Meyer, Georgia Chatzinikolaou, Kalliopi Stratigi, George A. Garinis, Björn Schumacher

Nat Struct Mol Biol. 2023; 30(4): 475–488. Published online 2023 Mar 23. doi: 10.1038/s41594-023-00942-8

PMCID:: PMC10113156

Abstract Article PDF–13M

Select item 100186478.

C. elegans Gonad Dissection and Freeze Crack for Immunofluorescence and DAPI Staining

Deepshikha Ananthaswamy, Jaime C. Croft, Natilia Woozencroft, Teresa W. Lee

J Vis Exp. Author manuscript; available in PMC 2023 Mar 16.

Published in final edited form as: J Vis Exp. 2022 Sep 16; (187): 10.3791/64204. Published online 2022 Sep 16. doi: 10.3791/64204

PMCID:: PMC10018647

Abstract Article PDF–749K

Select item 99107979.

Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line

Qianyan Li, Arshdeep Kaur, Kyoko Okada, Richard J. McKenney, JoAnne Engebrecht

PLoS Genet. 2023 Jan; 19(1): e1010457. Published online 2023 Jan 30. doi: 10.1371/journal.pgen.1010457

PMCID:: PMC9910797

Abstract Article PDF–3.6M

Select item 990781810.

Chromatin landscape, DSB levels, and cKU-70/80 contribute to patterning of meiotic DSB processing along chromosomes in C. elegans

Laura I. Lascarez-Lagunas, Marina Martinez-Garcia, Saravanapriah Nadarajan, Brianna N. Diaz-Pacheco, Elizaveta Berson, Mónica P. Colaiácovo

PLoS Genet. 2023 Jan; 19(1): e1010627. Published online 2023 Jan 27. doi: 10.1371/journal.pgen.1010627

PMCID:: PMC9907818

Abstract Article PDF–3.6M

Select item 984141511.

Unscheduled epigenetic modifications cause genome instability and sterility through aberrant R-loops following starvation

Bing Sun, McLean Sherrin, Richard Roy

Nucleic Acids Res. 2023 Jan 11; 51(1): 84–98. Published online 2022 Dec 12. doi: 10.1093/nar/gkac1155

PMCID:: PMC9841415

Abstract Article PDF–5.4M

Select item 983405612.

Inheritance of paternal DNA damage by histone-mediated repair restriction

Siyao Wang, David H. Meyer, Björn Schumacher

Nature. 2023; 613(7943): 365–374. Published online 2022 Dec 21. doi: 10.1038/s41586-022-05544-w

PMCID:: PMC9834056

Abstract Article PDF–23M

Select item 975704213.

PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis

Shalini Trivedi, Jitka Blazícková, Nicola Silva

Nucleic Acids Res. 2022 Nov 28; 50(21): 12291–12308. Published online 2022 Dec 8. doi: 10.1093/nar/gkac1153

PMCID:: PMC9757042

Abstract Article PDF–25M

Select item 964361314.

ATM/ATR kinases link the synaptonemal complex and DNA double-strand break repair pathway choice

Laura I. Láscarez-Lagunas, Saravanapriah Nadarajan, Marina Martinez-Garcia, Julianna Nicole Quinn, Elena Todisco, Tanuj Thakkar, Elizaveta Berson, Don Eaford, Oliver Crawley, Alex Montoya, Peter Faull, Nuria Ferrandiz, Consuelo Barroso, Sara Labella, Emily Koury, Sarit Smolikove, Monique Zetka, Enrique Martinez-Perez, Monica P. Colaiácovo

Curr Biol. Author manuscript; available in PMC 2023 Nov 7.

Published in final edited form as: Curr Biol. 2022 Nov 7; 32(21): 4719–4726.e4. Published online 2022 Sep 21. doi: 10.1016/j.cub.2022.08.081