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Select item 110656891.

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis

Marisol Alvarez-Martinez, Luke S. Cox, Claire F. Pearson, William J. Branchett, Probir Chakravarty, Xuemei Wu, Hubert Slawinski, Alaa Al-Dibouni, Vasileios A. Samelis, Leona Gabryšová, Simon L. Priestnall, Alejandro Suárez-Bonnet, Anna Mikolajczak, James Briscoe, Fiona Powrie, Anne O’Garra

Nat Immunol. 2024; 25(5): 886–901. Published online 2024 Apr 12. doi: 10.1038/s41590-024-01814-z

PMCID:: PMC11065689

Abstract Article PDF–34M

Select item 109649502.

Intestinal microbiota-specific T_h17 cells possess regulatory properties and suppress effector T cells via c-MAF and IL-10

Leonie Brockmann, Alexander Tran, Yiming Huang, Madeline Edwards, Carlotta Ronda, Harris H. Wang, Ivaylo I. Ivanov

Immunity. Author manuscript; available in PMC 2024 Dec 12.

Published in final edited form as: Immunity. 2023 Dec 12; 56(12): 2719–2735.e7. Published online 2023 Nov 30. doi: 10.1016/j.immuni.2023.11.003

PMCID:: PMC10964950

Abstract Article PDF–3.5M

Select item 109426173.

Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2

Simon Desiderio, Frederick Schwaller, Kevin Tartour, Kiran Padmanabhan, Gary R Lewin, Patrick Carroll, Frederic Marmigere

eLife. 2024; 12: RP89287. Published online 2024 Feb 22. doi: 10.7554/eLife.89287

PMCID:: PMC10942617

Abstract Article PDF–11M

Select item 109176604.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105454375.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 103567716.

Opposing gene regulatory programs governing myofiber development and maturation revealed at single nucleus resolution

Matthieu Dos Santos, Akansha M. Shah, Yichi Zhang, Svetlana Bezprozvannaya, Kenian Chen, Lin Xu, Weichun Lin, John R. McAnally, Rhonda Bassel-Duby, Ning Liu, Eric N. Olson

Nat Commun. 2023; 14: 4333. Published online 2023 Jul 19. doi: 10.1038/s41467-023-40073-8

PMCID:: PMC10356771

Abstract Article PDF–4.9M

Select item 102905107.

A bifurcated role for c-Maf in Th2 and Tfh2 cells during helminth infection

Katherine Bao, Uryan Isik Can, Mindy M. Miller, Ivy K. Brown, Mark Dell’Aringa, Hans Dooms, Max A. Seibold, James Scott-Browne, Richard Lee Reinhardt

Mucosal Immunol. Author manuscript; available in PMC 2023 Jun 24.

Published in final edited form as: Mucosal Immunol. 2023 Jun; 16(3): 357–372. Published online 2023 Apr 22. doi: 10.1016/j.mucimm.2023.04.002

PMCID:: PMC10290510

Abstract Article PDF–2.6M

Select item 101823008.

Natural γδT17 cell development and functional acquisition is governed by the mTORC2-c-Maf-controlled mitochondrial fission pathway

Yunke Wang, Hui Qin, Yihua Cai, Xu Chen, Hong Li, Diego Elias Montoya-Durango, Chuanlin Ding, Xiaoling Hu, Julia H. Chariker, Harshini Sarojini, Sufan Chien, Eric C. Rouchka, Huang-Ge Zhang, Jie Zheng, Fuming Qiu, Jun Yan

iScience. 2023 May 19; 26(5): 106630. Published online 2023 Apr 10. doi: 10.1016/j.isci.2023.106630

PMCID:: PMC10182300

Abstract Article PDF–8.7M

Select item 101571399.

c-Maf-positive spinal cord neurons are critical elements of a dorsal horn circuit for mechanical hypersensitivity in neuropathy

Noémie Frezel, Matteo Ranucci, Edmund Foster, Hagen Wende, Pawel Pelczar, Raquel Mendes, Robert P. Ganley, Karolina Werynska, Simon d’Aquin, Camilla Beccarini, Carmen Birchmeier, Hanns Ulrich Zeilhofer, Hendrik Wildner

Cell Rep. 2023 Apr 25; 42(4): 112295. Published online 2023 Mar 21. doi: 10.1016/j.celrep.2023.112295

PMCID:: PMC10157139

Abstract Article PDF–8.1M

Select item 1015421110.

MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation

Domien Vanneste, Qiang Bai, Shakir Hasan, Wen Peng, Dimitri Pirottin, Joey Schyns, Pauline Maréchal, Cecilia Ruscitti, Margot Meunier, Zhaoyuan Liu, Céline Legrand, Laurence Fievez, Florent Ginhoux, Coraline Radermecker, Fabrice Bureau, Thomas Marichal

Nat Immunol. 2023; 24(5): 827–840. Published online 2023 Mar 16. doi: 10.1038/s41590-023-01468-3

PMCID:: PMC10154211

Abstract Article PDF–12M

Select item 1011292911.

Maf family transcription factors are required for nutrient uptake in the mouse neonatal gut

Anne M. Bara, Lei Chen, Celina Ma, Julie Underwood, Rebecca S. Moreci, Kaelyn Sumigray, Tongyu Sun, Yarui Diao, Michael Verzi, Terry Lechler

Development. 2022 Dec 1; 149(23): dev201251. Published online 2022 Dec 12. doi: 10.1242/dev.201251

PMCID:: PMC10112929

Abstract Article

Select item 1007011512.

Transcription factor c-Maf deletion improves streptozotocin-induced diabetic nephropathy by directly regulating Sglt2 and Glut2

Mitsunori Fujino, Naoki Morito, Takuto Hayashi, Masami Ojima, Shun Ishibashi, Akihiro Kuno, Seizo Koshiba, Kunihiro Yamagata, Satoru Takahashi

JCI Insight. 2023 Mar 22; 8(6): e163306. Published online 2023 Mar 22. doi: 10.1172/jci.insight.163306

PMCID:: PMC10070115

Abstract Article PDF–14M

Select item 948608513.

c-MAF coordinates enterocyte zonation and nutrient uptake transcriptional programs

Alejandra González-Loyola, Jeremiah Bernier-Latmani, Irena Roci, Tania Wyss, Jakob Langer, Stephan Durot, Olivia Munoz, Borja Prat-Luri, Mauro Delorenzi, Matthias P. Lutolf, Nicola Zamboni, Grégory Verdeil, Tatiana V. Petrova

J Exp Med. 2022 Dec 5; 219(12): e20212418. Published online 2022 Sep 19. doi: 10.1084/jem.20212418

PMCID:: PMC9486085

Abstract Article PDF–6.0M

Select item 948608414.

Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice

Catalina Cosovanu, Philipp Resch, Stefan Jordan, Andrea Lehmann, Markus Ralser, Vadim Farztdinov, Joachim Spranger, Michael Mülleder, Sebastian Brachs, Christian Neumann

J Exp Med. 2022 Dec 5; 219(12): e20220233. Published online 2022 Sep 19. doi: 10.1084/jem.20220233

PMCID:: PMC9486084

Abstract Article PDF–4.9M

Select item 929039315.

Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction

Jesus Maria Gómez-Salinero, Franco Izzo, Yang Lin, Sean Houghton, Tomer Itkin, Fuqiang Geng, Yaron Bram, Robert P. Adelson, Tyler M. Lu, Giorgio Ga. Inghirami, Jenny Zhaoying Xiang, Raphael Lis, David Redmond, Ryan Schreiner, Sina Y. Rabbany, Dan A. Landau, Robert E. Schwartz, Shahin Rafii

Cell Stem Cell. Author manuscript; available in PMC 2023 Apr 7.

Published in final edited form as: Cell Stem Cell. 2022 Apr 7; 29(4): 593–609.e7. Published online 2022 Mar 31. doi: 10.1016/j.stem.2022.03.002

PMCID:: PMC9290393

Abstract Article PDF–3.5M

Select item 919474416.

c‐Maf enforces cytokine production and promotes memory‐like responses in mouse and human type 2 innate lymphoid cells

Sara Trabanelli, Giuseppe Ercolano, Tania Wyss, Alejandra Gomez‐Cadena, Maryline Falquet, Daniela Cropp, Claire Imbratta, Marine M Leblond, Valentina Salvestrini, Antonio Curti, Olivier Adotevi, Camilla Jandus, Grégory Verdeil

EMBO J. 2022 Jun; 41(12): e109300. Published online 2022 Apr 25. doi: 10.15252/embj.2021109300

PMCID:: PMC9194744

Abstract Article PDF–1.5M

Select item 916965117.

Single cell enhancer activity distinguishes GABAergic and cholinergic lineages in embryonic mouse basal ganglia

Linda Su-Feher, Anna N. Rubin, Shanni N. Silberberg, Rinaldo Catta-Preta, Kenneth J. Lim, Athena R. Ypsilanti, Iva Zdilar, Christopher S. McGinnis, Gabriel L. McKinsey, Thomas E. Rubino, Jr., Michael J. Hawrylycz, Carol Thompson, Zev J. Gartner, Luis Puelles, Hongkui Zeng, John L. R. Rubenstein, Alex S. Nord

Proc Natl Acad Sci U S A. 2022 Apr 12; 119(15): e2108760119. Published online 2022 Apr 4. doi: 10.1073/pnas.2108760119

PMCID:: PMC9169651

Abstract Article PDF–3.9M

Select item 913244218.

Differential metabolic requirement governed by transcription factor c-Maf dictates innate γδT17 effector functionality in mice and humans

Xu Chen, Yihua Cai, Xiaoling Hu, Chuanlin Ding, Liqing He, Xiang Zhang, Fuxiang Chen, Jun Yan

Sci Adv. 2022 May; 8(21): eabm9120. Published online 2022 May 25. doi: 10.1126/sciadv.abm9120

PMCID:: PMC9132442

Abstract Article PDF–6.5M

Select item 888790319.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 872027320.

The aging mouse lens transcriptome

Adam P. Faranda, Mahbubul H. Shihan, Yan Wang, Melinda K. Duncan

Exp Eye Res. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Exp Eye Res. 2021 Aug; 209: 108663. Published online 2021 Jun 11. doi: 10.1016/j.exer.2021.108663

PMCID:: PMC8720273

Abstract Article PDF–1.8M

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