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Select item 109320351.

Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway

Taha Rehmani, Ana Paula Dias, Marsel Kamal, Maysoon Salih, Balwant S. Tuana

Int J Mol Sci. 2024 Mar; 25(5): 2888. Published online 2024 Mar 1. doi: 10.3390/ijms25052888

PMCID:: PMC10932035

Abstract Article PDF–4.4M

Select item 96038602.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 94819333.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 92262644.

Chk1 Inhibition Ameliorates Alzheimer’s Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling

Wenting Hu, Zhuoqun Wang, Huiliang Zhang, Yacoubou Abdoul Razak Mahaman, Fang Huang, Dongli Meng, Ying Zhou, Shiyi Wang, Nan Jiang, Jing Xiong, Jukka Westermarck, Youming Lu, Jianzhi Wang, Xiaochuan Wang, Yangping Shentu, Rong Liu

Neurotherapeutics. 2022 Mar; 19(2): 570–591. Published online 2022 Mar 14. doi: 10.1007/s13311-022-01204-z

PMCID:: PMC9226264

Abstract Article PDF–13M

Select item 91189235.

Protein phosphatase 2A regulates cytotoxicity and drug resistance by dephosphorylating AHR and MDR1

Liping Chen, Ping Guo, Wenxue Li, Xinhang Jiang, Qun Zhao, Daochuan Li, Qing Wang, Yongmei Xiao, Xiumei Xing, Yaqin Pang, Michael Aschner, Lihua Zhang, Wen Chen

J Biol Chem. 2022 May; 298(5): 101918. Published online 2022 Apr 8. doi: 10.1016/j.jbc.2022.101918

PMCID:: PMC9118923

Abstract Article PDF–5.5M

Select item 86743396.

Protein phosphatase 2A inactivation induces microsatellite instability, neoantigen production and immune response

Yu-Ting Yen, May Chien, Pei-Yi Wu, Chi-Chang Ho, Chun-Te Ho, Kevin Chih-Yang Huang, Shu-Fen Chiang, K. S. Clifford Chao, William Tzu-Liang Chen, Shih-Chieh Hung

Nat Commun. 2021; 12: 7297. Published online 2021 Dec 15. doi: 10.1038/s41467-021-27620-x

PMCID:: PMC8674339

Abstract Article PDF–2.9M

Select item 81725347.

PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation

Yu-Ting Yen, May Chien, Pei-Yi Wu, Shih-Chieh Hung

Commun Biol. 2021; 4: 658. Published online 2021 Jun 2. doi: 10.1038/s42003-021-02175-1

PMCID:: PMC8172534

Abstract Article PDF–5.1M

Select item 79387708.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72900529.

Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development

Nikita Panicker, Melody Coutman, Charley Lawlor-O’Neill, Richard G. S. Kahl, Séverine Roselli, Nicole M. Verrills

Front Cell Dev Biol. 2020; 8: 358. Published online 2020 Jun 5. doi: 10.3389/fcell.2020.00358

PMCID:: PMC7290052

Abstract Article PDF–2.8M

Select item 714138510.

Serine/threonine phosphatase PP2A is essential for optimal B cell function

Esra Meidan, Hao Li, Wenliang Pan, Michihito Kono, Shuilian Yu, Vasileios C. Kyttaris, Christina Ioannidis, Noe Rodriguez Rodriguez, Jose C. Crispin, Sokratis A. Apostolidis, Pui Lee, John Manis, Amir Sharabi, Maria G. Tsokos, George C. Tsokos

JCI Insight. 2020 Mar 12; 5(5): e130655. Published online 2020 Mar 12. doi: 10.1172/jci.insight.130655

PMCID:: PMC7141385

Abstract Article PDF–2.7M

Select item 701712911.

PP2A Deficiency Enhances Carcinogenesis of Lgr5⁺ Intestinal Stem Cells Both in Organoids and In Vivo

Yu-Ting Yen, May Chien, Yung-Chih Lai, Dao-Peng Chen, Cheng-Ming Chuong, Mien-Chie Hung, Shih-Chieh Hung

Cells. 2020 Jan; 9(1): 90. Published online 2019 Dec 30. doi: 10.3390/cells9010090

PMCID:: PMC7017129

Abstract Article PDF–4.1M

Select item 677811112.

Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes

Yifei Zhong, Kyung Lee, Yueyi Deng, Yueming Ma, Yiping Chen, Xueling Li, Chengguo Wei, Shumin Yang, Tianming Wang, Nicholas J. Wong, Alecia N. Muwonge, Evren U. Azeloglu, Weijia Zhang, Bhaskar Das, John Cijiang He, Ruijie Liu

Nat Commun. 2019; 10: 4523. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12433-w

PMCID:: PMC6778111

Abstract Article PDF–3.1M

Select item 669277013.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 660230014.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 658162415.

CD25 and protein phosphatase 2A cooperate to enhance IL-2R signaling in human regulatory T cells

Ying Ding, Aixin Yu, George C. Tsokos, Thomas R. Malek

J Immunol. Author manuscript; available in PMC 2020 Jul 1.

Published in final edited form as: J Immunol. 2019 Jul 1; 203(1): 93–104. Published online 2019 May 13. doi: 10.4049/jimmunol.1801570

PMCID:: PMC6581624

Abstract Article PDF–2.0M

Select item 655472316.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 653831417.

PP2A enables IL-2 signaling by preserving IL-2Rβ chain expression during Treg development

Amir Sharabi, Hao Li, Isaac R. Kasper, Wenliang Pan, Esra Meidan, Maria G. Tsokos, Vaishali R. Moulton, George C. Tsokos

JCI Insight. 2019 May 2; 4(9): e126294. Published online 2019 May 2. doi: 10.1172/jci.insight.126294

PMCID:: PMC6538314

Abstract Article PDF–1.1M

Select item 637897318.

Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1

Liping Chen, Ping Guo, Haiyan Zhang, Wenxue Li, Chen Gao, Zhenlie Huang, Junling Fan, Yuling Zhang, Xue Li, Xiaoling Liu, Fangping Wang, Shan Wang, Qingye Li, Zhini He, Huiyao Li, Shen Chen, Xiaonen Wu, Lizhu Ye, Qiong Li, Huanwen Tang, Qing Wang, Guanghui Dong, Yongmei Xiao, Wen Chen, Daochuan Li

J Biol Chem. 2019 Feb 15; 294(7): 2486–2499. Published online 2018 Dec 19. doi: 10.1074/jbc.RA118.006319

PMCID:: PMC6378973

Abstract Article PDF–3.4M

Select item 633346019.

ATG5 is required for B cell polarization and presentation of particulate antigens

Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros

Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327

PMCID:: PMC6333460

Abstract Article PDF–2.7M

Select item 631390020.

Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization

Darryl S. Watkins, Jason D. True, Amber L. Mosley, Anthony J. Baucum, II

Proteomes. 2018 Dec; 6(4): 53. Published online 2018 Dec 17. doi: 10.3390/proteomes6040053

Correction in:: Proteomes. 2019 Mar; 7(1): 7.

PMCID:: PMC6313900

Abstract Article PDF–2.5M

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