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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Article PDF–4.8M

Select item 103078522.

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility

Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao

Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5

PMCID:: PMC10307852

Article PDF–8.8M

Select item 96750513.

CTRP4 ablation impairs associative learning and memory

Dylan C. Sarver, Cheng Xu, Yi Cheng, Chantelle E. Terrillion, G. William Wong

FASEB J. Author manuscript; available in PMC 2022 Nov 19.

Published in final edited form as: FASEB J. 2021 Nov; 35(11): e21910. doi: 10.1096/fj.202100733RR

PMCID:: PMC9675051

Article PDF–2.4M

Select item 82866094.

Liu Ye, Gongwei Jia, Yuejie Li, Ying Wang, Hong Chen, Lehua Yu, Dandong Wu

J Neuroinflammation. 2021; 18: 159. Published online 2021 Jul 18. doi: 10.1186/s12974-021-02167-2

PMCID:: PMC8286609

Article PDF–2.1M

Select item 77926655.

Loss of CTRP4 alters adiposity and food intake behaviors in obese mice

Dylan C. Sarver, Ashley N. Stewart, Susana Rodriguez, Hannah C. Little, Susan Aja, G. William Wong

Am J Physiol Endocrinol Metab. 2020 Dec 1; 319(6): E1084–E1100. Published online 2020 Oct 5. doi: 10.1152/ajpendo.00448.2020

PMCID:: PMC7792665

Article

Select item 62980406.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Article PDF–1.2M

Select item 62774127.

MTCH2-mediated mitochondrial fusion drives exit from naïve pluripotency in embryonic stem cells

Amir Bahat, Andres Goldman, Yehudit Zaltsman, Dilshad H. Khan, Coral Halperin, Emmanuel Amzallag, Vladislav Krupalnik, Michael Mullokandov, Alon Silberman, Ayelet Erez, Aaron D. Schimmer, Jacob H. Hanna, Atan Gross

Nat Commun. 2018; 9: 5132. Published online 2018 Dec 3. doi: 10.1038/s41467-018-07519-w

PMCID:: PMC6277412

Article PDF–1.7M

Select item 62441838.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Article PDF–753K

Select item 57953889.

The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes

Fan Liu, Philip Lössl, Beverley M. Rabbitts, Robert S. Balaban, Albert J. R. Heck

Mol Cell Proteomics. 2018 Feb; 17(2): 216–232. Published online 2017 Dec 8. doi: 10.1074/mcp.RA117.000470

PMCID:: PMC5795388

Article PDF–4.4M

Select item 534359010.

Loss of forebrain MTCH2 decreases mitochondria motility and calcium handling and impairs hippocampal-dependent cognitive functions

Antonella Ruggiero, Etay Aloni, Eduard Korkotian, Yehudit Zaltsman, Efrat Oni-Biton, Yael Kuperman, Michael Tsoory, Liat Shachnai, Smadar Levin-Zaidman, Ori Brenner, Menahem Segal, Atan Gross

Sci Rep. 2017; 7: 44401. Published online 2017 Mar 9. doi: 10.1038/srep44401

PMCID:: PMC5343590

Article PDF–1.6M

Select item 529582111.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Article PDF–3.0M

Select item 503728412.

Expression of the novel adipokine C1qTNF-related protein 4 (CTRP4) suppresses colitis and colitis-associated colorectal cancer in mice

Yang Luo, Xiaotong Wu, Zhuang Ma, Weifeng Tan, Lanlan Wang, Daxiang Na, Guoying Zhang, Ang Yin, He Huang, Dan Xia, Yingmei Zhang, Xueying Shi, Lu Wang

Cell Mol Immunol. 2016 Sep; 13(5): 688–699. Published online 2016 Apr 18. doi: 10.1038/cmi.2016.16

PMCID:: PMC5037284

Article PDF–11M

Select item 494832413.

Genome engineering uncovers 54 evolutionarily conserved and testis-enriched genes that are not required for male fertility in mice

Haruhiko Miyata, Julio M. Castaneda, Yoshitaka Fujihara, Zhifeng Yu, Denise R. Archambeault, Ayako Isotani, Daiji Kiyozumi, Maya L. Kriseman, Daisuke Mashiko, Takafumi Matsumura, Ryan M. Matzuk, Masashi Mori, Taichi Noda, Asami Oji, Masaru Okabe, Renata Prunskaite-Hyyrylainen, Ramiro Ramirez-Solis, Yuhkoh Satouh, Qian Zhang, Masahito Ikawa, Martin M. Matzuk

Proc Natl Acad Sci U S A. 2016 Jul 12; 113(28): 7704–7710. Published online 2016 Jun 29. doi: 10.1073/pnas.1608458113

PMCID:: PMC4948324

Article PDF–902K

Select item 492886914.

Mimp/Mtch2, an Obesity Susceptibility Gene, Induces Alteration of Fatty Acid Metabolism in Transgenic Mice

Yamit Bar-Lev, Sharon Moshitch-Moshkovitz, Galia Tsarfaty, Dafna Kaufman, Judith Horev, James H. Resau, Ilan Tsarfaty

PLoS One. 2016; 11(6): e0157850. Published online 2016 Jun 30. doi: 10.1371/journal.pone.0157850

PMCID:: PMC4928869

Article PDF–4.4M

Select item 460561015.

Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome

Julianne H. Grose, Kelsey Langston, Xiaohui Wang, Shayne Squires, Soumyajit Banerjee Mustafi, Whitney Hayes, Jonathan Neubert, Susan K. Fischer, Matthew Fasano, Gina Moore Saunders, Qiang Dai, Elisabeth Christians, E. Douglas Lewandowski, Peipei Ping, Ivor J. Benjamin

PLoS One. 2015; 10(10): e0133994. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0133994

PMCID:: PMC4605610

Article PDF–6.8M

Select item 411301516.

Programmed Translational Readthrough Generates Anti-Angiogenic VEGF-Ax

Sandeepa M. Eswarappa, Alka A. Potdar, William J. Koch, Yi Fan, Kommireddy Vasu, Daniel Lindner, Belinda Willard, Linda M. Graham, Paul E. DiCorleto, Paul L. Fox

Cell. Author manuscript; available in PMC 2015 Jun 19.

Published in final edited form as: Cell. 2014 Jun 19; 157(7): 1605–1618. doi: 10.1016/j.cell.2014.04.033

PMCID:: PMC4113015

Article PDF–1.6M

Select item 407349417.

The Central Role of EED in the Orchestration of Polycomb Group Complexes

Qi Cao, Xiaoju Wang, Meng Zhao, Rendong Yang, Rohit Malik, Yuanyuan Qiao, Anton Poliakov, Anastasia K. Yocum, Yong Li, Wei Chen, Xuhong Cao, Xia Jiang, Arun Dahiya, Clair Harris, Felix Y. Feng, Sundeep Kalantry, Zhaohui S. Qin, Saravana M. Dhanasekaran, Arul M. Chinnaiyan

Nat Commun. Author manuscript; available in PMC 2014 Jul 24.

Published in final edited form as: Nat Commun. 2014; 5: 3127. doi: 10.1038/ncomms4127

PMCID:: PMC4073494

Article PDF–2.1M

Select item 407087918.

MTCH2/MIMP is a major facilitator of tBID recruitment to mitochondria

Yehudit Zaltsman, Liat Shachnai, Natalie Yivgi-Ohana, Michal Schwarz, Maria Maryanovich, Riekelt H. Houtkooper, Frédéric Maxime Vaz, Francesco De Leonardis, Giuseppe Fiermonte, Ferdinando Palmieri, Bernhard Gillissen, Peter T. Daniel, Erin Jimenez, Susan Walsh, Carla M. Koehler, Soumya Sinha Roy, Ludivine Walter, György Hajnóczky, Atan Gross

Nat Cell Biol. Author manuscript; available in PMC 2014 Jun 25.

Published in final edited form as: Nat Cell Biol. 2010 Jun; 12(6): 553–562. Published online 2010 May 2. doi: 10.1038/ncb2057

PMCID:: PMC4070879

Article PDF–2.9M

Select item 396495519.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Article PDF–5.7M

Select item 392427220.

Mardi S. Byerly, Pia S. Petersen, Santosh Ramamurthy, Marcus M. Seldin, Xia Lei, Elayne Provost, Zhikui Wei, Gabriele V. Ronnett, G. William Wong

J Biol Chem. 2014 Feb 14; 289(7): 4055–4069. Published online 2013 Dec 23. doi: 10.1074/jbc.M113.506956

PMCID:: PMC3924272

Article PDF–3.2M

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