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Items: 1 to 20 of 226

1.
RORα–GABP–TFAM axis alleviates myosteatosis with fatty atrophy through reinforcement of mitochondrial capacity
Hyeon‐Ji Kim, Sang‐Heon Lee, Cheolhee Jeong, Yong‐Hyun Han, Mi‐Ock Lee
J Cachexia Sarcopenia Muscle. 2024 Apr; 15(2): 615–630. Published online 2024 Jan 25. doi: 10.1002/jcsm.13432
PMCID:
PMC10995264
AbstractArticlePDF–5.2M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model
Winston T. Stauffer, Asha Z. Goodman, Michael Bobardt, Daren R. Ure, Robert T. Foster, Philippe Gallay
PLoS One. 2024; 19(3): e0298211. Published online 2024 Mar 1. doi: 10.1371/journal.pone.0298211
PMCID:
PMC10906846
AbstractArticlePDF–3.5M
4.
Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development
Masatoshi Hirayama, Ludovic S. Mure, Hiep D. Le, Satchidananda Panda
iScience. 2024 Mar 15; 27(3): 109051. Published online 2024 Jan 30. doi: 10.1016/j.isci.2024.109051
PMCID:
PMC10879699
AbstractArticlePDF–5.2M
5.
RORα overexpression reduced interleukin‐33 expression and prevented mast cell degranulation and inflammation by inducing autophagy in allergic rhinitis
Wangbo Yu, Jingwei Du, Lijuan Peng, Tao Zhang
Immun Inflamm Dis. 2023 Oct; 11(10): e1017. Published online 2023 Oct 17. doi: 10.1002/iid3.1017
PMCID:
PMC10580702
AbstractArticlePDF–5.6M
6.
Retinoic Acid–Related Orphan Receptor α Is Required for Generation of Th2 Cells in Type 2 Pulmonary Inflammation
Joseph Roberts, Anne Chevalier, Heike C. Hawerkamp, Aoife Yeow, Laura Matarazzo, Christian Schwartz, Emily Hams, Padraic G. Fallon
J Immunol. 2023 Aug 15; 211(4): 626–632. Published online 2023 Jun 30. doi: 10.4049/jimmunol.2200896
PMCID:
PMC10404816
AbstractArticlePDF–1.3M
7.
Phospholipid scramblase-1 regulates innate type 2 inflammation in mouse lungs via CRTH2-dependent mechanisms
Ashley Hernandez-Gutierrez, Sonoor Majid, Adam Eberle, Ashley Choi, Parand Sorkhdini, Dongqin Yang, Alina Xiaoyu Yang, Carmelissa Norbrun, Chuan Hua He, Chang-min Lee, Chun Geun Lee, Jack A. Elias, Yang Zhou
J Clin Invest. 2023 Aug 1; 133(15): e169583. Published online 2023 Aug 1. doi: 10.1172/JCI169583
PMCID:
PMC10378191
AbstractArticlePDF–7.3M
8.
Epidermal Loss of RORα Enhances Skin Inflammation in a MC903-Induced Mouse Model of Atopic Dermatitis
Xiangmei Hua, Conrad Dean Blosch, Hannah Dorsey, Maria K. Ficaro, Nicole L. Wallace, Richard P. Hsung, Jun Dai
Int J Mol Sci. 2023 Jun; 24(12): 10241. Published online 2023 Jun 16. doi: 10.3390/ijms241210241
PMCID:
PMC10298918
AbstractArticlePDF–6.0M
9.
The circadian demethylation of a unique intronic deoxymethylCpG-rich island boosts the transcription of its cognate circadian clock output gene
Nisha Misra, Manohar Damara, Tao Ye, Pierre Chambon
Proc Natl Acad Sci U S A. 2023 Feb 21; 120(8): e2214062120. Published online 2023 Feb 15. doi: 10.1073/pnas.2214062120
PMCID:
PMC9974474
AbstractArticlePDF–1.1M
10.
Transcriptional control of cone photoreceptor diversity by a thyroid hormone receptor
Michihiko Aramaki, Xuefeng Wu, Hong Liu, Ye Liu, Young-Wook Cho, Mina Song, Yulong Fu, Lily Ng, Douglas Forrest
Proc Natl Acad Sci U S A. 2022 Dec 6; 119(49): e2209884119. Published online 2022 Dec 1. doi: 10.1073/pnas.2209884119
PMCID:
PMC9894165
AbstractArticlePDF–2.6M
11.
Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation
Kiya W. Govek, Sixing Chen, Paraskevi Sgourdou, Yao Yao, Steven Woodhouse, Tingfang Chen, Marc V. Fuccillo, Douglas J. Epstein, Pablo G. Camara
Cell Rep. Author manuscript; available in PMC 2023 Jan 27.
Published in final edited form as: Cell Rep. 2022 Dec 6; 41(10): 111768. doi: 10.1016/j.celrep.2022.111768
PMCID:
PMC9880597
AbstractArticlePDF–2.4M
12.
Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization
Chi-Hsiu Liu, Felix Yemanyi, Kiran Bora, Neetu Kushwah, Alexandra K. Blomfield, Theodore M. Kamenecka, John Paul SanGiovanni, Ye Sun, Laura A. Solt, Jing Chen
Aging (Albany NY) 2023 Jan 15; 15(1): 37–52. Published online 2023 Jan 10. doi: 10.18632/aging.204480
PMCID:
PMC9876633
AbstractArticlePDF–1.4M
13.
Transcription factor RORα enforces stability of the Th17 cell effector program by binding to a Rorc cis-regulatory element
Jason A. Hall, Maria Pokrovskii, Lina Kroehling, Bo-Ram Kim, Seung Yong Kim, Lin Wu, June-Yong Lee, Dan R. Littman
Immunity. Author manuscript; available in PMC 2022 Dec 16.
Published in final edited form as: Immunity. 2022 Nov 8; 55(11): 2027–2043.e9. Published online 2022 Oct 14. doi: 10.1016/j.immuni.2022.09.013
PMCID:
PMC9757081
AbstractArticlePDF–3.2M
14.
O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development
Sanjiv Neupane, Steven J. Berardinelli, Daniel C. Cameron, Richard C. Grady, David E. Komatsu, Christopher J. Percival, Megumi Takeuchi, Atsuko Ito, Ta-Wei Liu, Alison V. Nairn, Kelley W. Moremen, Robert S. Haltiwanger, Bernadette C. Holdener
Matrix Biol. Author manuscript; available in PMC 2022 Oct 27.
Published in final edited form as: Matrix Biol. 2022 Mar; 107: 77–96. Published online 2022 Feb 12. doi: 10.1016/j.matbio.2022.02.002
PMCID:
PMC9606722
AbstractArticlePDF–6.7M
15.
Novel antigen-presenting cell imparts Treg-dependent tolerance to gut microbiota
Blossom Akagbosu, Zakieh Tayyebi, Gayathri Shibu, Yoselin A. Paucar Iza, Deeksha Deep, Yollanda Franco Parisotto, Logan Fisher, H. Amalia Pasolli, Valentin Thevin, Rasa Elmentaite, Maximilian Knott, Saskia Hemmers, Lorenz Jahn, Christin Friedrich, Jacob Verter, Zhong-Min Wang, Marcel van den Brink, Georg Gasteiger, Thomas G. P. Grünewald, Julien C. Marie, Christina Leslie, Alexander Y. Rudensky, Chrysothemis C. Brown
Nature. 2022; 610(7933): 752–760. Published online 2022 Sep 7. doi: 10.1038/s41586-022-05309-5
PMCID:
PMC9605865
AbstractArticlePDF–14M
16.
Temporally divergent regulatory mechanisms govern neuronal diversification and maturation in the mouse and marmoset neocortex
Wen Yuan, Sai Ma, Juliana R. Brown, Kwanho Kim, Vanessa Murek, Lucia Trastulla, Alexander Meissner, Simona Lodato, Ashwin S. Shetty, Joshua Z. Levin, Jason D. Buenrostro, Michael J. Ziller, Paola Arlotta
Nat Neurosci. 2022; 25(8): 1049–1058. Published online 2022 Aug 1. doi: 10.1038/s41593-022-01123-4
PMCID:
PMC9343253
AbstractArticlePDF–17M
17.
Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex
Timothy Monko, Jaclyn Rebertus, Jeff Stolley, Stephen R. Salton, Yasushi Nakagawa
Proc Natl Acad Sci U S A. 2022 May 31; 119(22): e2201355119. Published online 2022 May 25. doi: 10.1073/pnas.2201355119
PMCID:
PMC9295754
AbstractArticlePDF–3.8M
18.
Vertebrate lonesome kinase modulates the hepatocyte secretome to prevent perivascular liver fibrosis and inflammation
Sophia Pantasis, Juliane Friemel, Salome Mirjam Brütsch, Zehan Hu, Sabrina Krautbauer, Gerhard Liebisch, Joern Dengjel, Achim Weber, Sabine Werner, Mattia Renato Bordoli
J Cell Sci. 2022 Apr 1; 135(7): jcs259243. Published online 2022 Apr 12. doi: 10.1242/jcs.259243
PMCID:
PMC9016620
AbstractArticle
19.
The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis
Ning Li, Nan Wang, Wei He, Yunyu Feng, Qiang Qiu, Huandi Qiu, Li Zheng, Yuexia Yin, Bochuan Wang, Yuanyuan Sun, Cong Pan, Klarke M. Sample, Juan Huang, Zhiguang Su, Zhihui Li, Haojian Zhang, Yiguo Hu
Int J Biol Sci. 2022; 18(6): 2277–2291. Published online 2022 Mar 6. doi: 10.7150/ijbs.68939
PMCID:
PMC8990459
AbstractArticlePDF–3.4M
20.
Thalamocortical axons control the cytoarchitecture of neocortical layers by area-specific supply of VGF
Haruka Sato, Jun Hatakeyama, Takuji Iwasato, Kimi Araki, Nobuhiko Yamamoto, Kenji Shimamura
eLife. 2022; 11: e67549. Published online 2022 Mar 15. doi: 10.7554/eLife.67549
PMCID:
PMC8959604
AbstractArticlePDF–6.6M

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