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Select item 109876621.

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin

Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan

EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y

PMCID:: PMC10987662

Abstract Article PDF–12M

Select item 108350412.

Single-cell RNA sequencing unveils unique transcriptomic signatures of endothelial cells and role of ENO1 in response to disturbed flow

Li-Jing Chen, Julie Yi-Shuan Li, Phu Nguyen, Ming He, Zhen Bouman Chen, Shankar Subramaniam, John Y.-J. Shyy, Shu Chien

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2318904121. Published online 2024 Jan 23. doi: 10.1073/pnas.2318904121

PMCID:: PMC10835041

Abstract Article PDF–3.5M

Select item 105682543.

Unrevealed roles of extracellular enolase‑1 (ENO1) in promoting glycolysis and pro‑cancer activities in multiple myeloma via hypoxia‑inducible factor 1α

I-Che Chung, Wei-Ching Huang, Yung-Tsang Huang, Mao-Lin Chen, An-Wei Tsai, Pei-Yu Wu, Ta-Tung Yuan

Oncol Rep. 2023 Nov; 50(5): 205. Published online 2023 Oct 3. doi: 10.3892/or.2023.8642

PMCID:: PMC10568254

Abstract Article PDF–3.8M

Select item 104077454.

Deficiency of the metabolic enzyme SCHAD in pancreatic β-cells promotes amino acid–sensitive hypoglycemia

Johanna L. St-Louis, Khadija El Jellas, Kelly Velasco, Brittany A. Slipp, Jiang Hu, Geir Helgeland, Solrun J. Steine, Dario F. De Jesus, Rohit N. Kulkarni, Anders Molven

J Biol Chem. 2023 Aug; 299(8): 104986. Published online 2023 Jun 29. doi: 10.1016/j.jbc.2023.104986

PMCID:: PMC10407745

Abstract Article PDF–1.8M

Select item 96038605.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 95539516.

Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming

Danyang Chong, Yayun Gu, Tongyu Zhang, Yu Xu, Dandan Bu, Zhong Chen, Na Xu, Liangkui Li, Xiyu Zhu, Haiquan Wang, Yangqing Li, Feng Zheng, Dongjin Wang, Peng Li, Li Xu, Zhibin Hu, Chaojun Li

Cell Discov. 2022; 8: 106. Published online 2022 Oct 11. doi: 10.1038/s41421-022-00447-6

PMCID:: PMC9553951

Abstract Article PDF–3.8M

Select item 89880087.

Deletion of hypoxia-inducible factor prolyl 4-hydroxylase 2 in FoxD1-lineage mesenchymal cells leads to congenital truncal alopecia

Ann-Helen Rosendahl, Mia Monnius, Anu Laitala, Antti Railo, Ilkka Miinalainen, Ritva Heljasvaara, Joni M. Mäki, Johanna Myllyharju

J Biol Chem. 2022 Apr; 298(4): 101787. Published online 2022 Mar 2. doi: 10.1016/j.jbc.2022.101787

PMCID:: PMC8988008

Abstract Article PDF–6.1M

Select item 87906008.

Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

Jun Seok Son, Song Ah Chae, Liang Zhao, Hongyang Wang, Jeanene M. de Avila, Mei-Jun Zhu, Zhihua Jiang, Min Du

EBioMedicine. 2022 Feb; 76: 103842. Published online 2022 Jan 23. doi: 10.1016/j.ebiom.2022.103842

PMCID:: PMC8790600

Abstract Article PDF–4.3M

Select item 83132399.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 798315610.

IL-7-induced phosphorylation of the adaptor Crk-like and other targets

Francesca B. Aiello, Tad Guszczynski, Wenqing Li, Julie A. Hixon, Qiong Jiang, Deborah L. Hodge, Tania Massignan, Chiara Di Lisio, Anand Merchant, Antonio D. Procopio, Valentina Bonetto, Scott K. Durum

Cell Signal. Author manuscript; available in PMC 2021 Mar 22.

Published in final edited form as: Cell Signal. 2018 Jul; 47: 131–141. Published online 2018 Mar 24. doi: 10.1016/j.cellsig.2018.03.008

PMCID:: PMC7983156

Abstract Article PDF–1.7M

Select item 793877011.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 741599112.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 736849413.

The sperm associated antigen 6 interactome and its role in spermatogenesis

Yunhao Liu, Ling Zhang, Wei Li, Yuhong Li, Junpin Liu, Shiyang Zhang, Guanglun Pin, Shizhen Song, Pierre F Ray, Christophe Arnoult, Chunghee Cho, Balbina Garcia-Reyes, Uwe Knippschild, Jerome F. Strauss, III, Zhibing Zhang

Reproduction. Author manuscript; available in PMC 2020 Jul 18.

Published in final edited form as: Reproduction. 2019 Aug; 158(2): 181–197. doi: 10.1530/REP-18-0522

PMCID:: PMC7368494

Abstract Article PDF–1.8M

Select item 699392514.

Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers

Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang

FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R

PMCID:: PMC6993925

Abstract Article

Select item 669277015.

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics

Joel D. Federspiel, Todd M. Greco, Krystal K. Lum, Ileana M. Cristea

Mol Cell Proteomics. 2019 Aug 9; 18(8 Suppl 1): S92–S113. Published online 2019 Apr 30. doi: 10.1074/mcp.RA118.001253

PMCID:: PMC6692770

Abstract Article PDF–7.7M

Select item 662917616.

Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice

Senlin Huang, Xinzhong Li, Hao Zheng, Xiaoyun Si, Bing Li, Guoquan Wei, Chuling Li, Yijin Chen, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin

Circulation. 2019 Jun 18; 139(25): 2857–2876. Published online 2019 Apr 5. doi: 10.1161/CIRCULATIONAHA.118.038361

PMCID:: PMC6629176

Abstract Article PDF–5.1M

Select item 662242617.

Von Hippel-Lindau Acts as a Metabolic Switch Controlling Nephron Progenitor Differentiation

Kasey Cargill, Shelby L. Hemker, Andrew Clugston, Anjana Murali, Elina Mukherjee, Jiao Liu, Daniel Bushnell, Andrew J. Bodnar, Zubaida Saifudeen, Jacqueline Ho, Carlton M. Bates, Dennis Kostka, Eric S. Goetzman, Sunder Sims-Lucas

J Am Soc Nephrol. 2019 Jul; 30(7): 1192–1205. Published online 2019 May 29. doi: 10.1681/ASN.2018111170

PMCID:: PMC6622426

Abstract Article

Select item 652253518.

Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner

Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer

Nat Commun. 2019; 10: 2192. Published online 2019 May 16. doi: 10.1038/s41467-019-09823-5

PMCID:: PMC6522535

Abstract Article PDF–7.1M

Select item 634668519.

Plasticity in the Glucagon Interactome Reveals Novel Proteins That Regulate Glucagon Secretion in α-TC1-6 Cells

Farzad Asadi, Savita Dhanvantari

Front Endocrinol (Lausanne) 2018; 9: 792. Published online 2019 Jan 18. doi: 10.3389/fendo.2018.00792

PMCID:: PMC6346685

Abstract Article PDF–3.6M

Select item 634600120.

ENOblock inhibits the pathology of diet-induced obesity

Haaglim Cho, Ji-Hyung Lee, JungIn Um, Sunwook Kim, Yukyung Kim, Woong-Hee Kim, Yong Sook Kim, Haushabhau S. Pagire, Jin Hee Ahn, Youngkeun Ahn, Young-Tae Chang, Da-Woon Jung, Darren R. Williams

Sci Rep. 2019; 9: 493. Published online 2019 Jan 24. doi: 10.1038/s41598-018-36715-3

PMCID:: PMC6346001

Abstract Article PDF–3.9M

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