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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 109006992.

Crucial role of TFAP2B in the nervous system for regulating NREM sleep

Ayaka Nakai, Mitsuaki Kashiwagi, Tomoyuki Fujiyama, Kanako Iwasaki, Arisa Hirano, Hiromasa Funato, Masashi Yanagisawa, Takeshi Sakurai, Yu Hayashi

Mol Brain. 2024; 17: 13. Published online 2024 Feb 27. doi: 10.1186/s13041-024-01084-8

PMCID:: PMC10900699

Abstract Article PDF–1.7M

Select item 108666623.

KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions, and their impairment causes aplasia cutis

Jackelyn R. Raymundo, Hui Zhang, Giovanni Smaldone, Wenjuan Zhu, Kathleen E. Daly, Benjamin J. Glennon, Giovanni Pecoraro, Marco Salvatore, William A. Devine, Cecilia W. Lo, Luigi Vitagliano, Alexander G. Marneros

J Clin Invest. 2024 Feb 15; 134(4): e174138. Published online 2023 Dec 19. doi: 10.1172/JCI174138

PMCID:: PMC10866662

Abstract Article PDF–143M

Select item 108208864.

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway

Timothy T. Nguyen, Jennyfer M. Mitchell, Michaela D. Kiel, Colin P. Kenny, Hong Li, Kenneth L. Jones, Robert A. Cornell, Trevor J. Williams, James T. Nichols, Eric Van Otterloo

Development. 2024 Jan 1; 151(1): dev202095. Published online 2024 Jan 2. doi: 10.1242/dev.202095

PMCID:: PMC10820886

Abstract Article

Select item 101923515.

Tfap2b acts in GABAergic neurons to control sleep in mice

Yang Hu, Henrik Bringmann

Sci Rep. 2023; 13: 8026. Published online 2023 May 17. doi: 10.1038/s41598-023-34772-x

PMCID:: PMC10192351

Abstract Article PDF–2.7M

Select item 100774766.

Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility

Meng Zou, Kevin D. Mangum, Justin C. Magin, Heidi H. Cao, Michael T. Yarboro, Elaine L. Shelton, Joan M. Taylor, Jeff Reese, Terrence S. Furey, Christopher P. Mack

JCI Insight. 2023 Mar 8; 8(5): e163454. Published online 2023 Mar 8. doi: 10.1172/jci.insight.163454

PMCID:: PMC10077476

Abstract Article PDF–22M

Select item 99887037.

Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV)

Yuanyuan Chen, Cheng Wu, Shanzhen Peng, Dianlei Guo, Hong Ouyang, Yanhong Wei, Rong Ju, Xiaoyan Ding, Zhi Xie, Chunqiao Liu

Invest Ophthalmol Vis Sci. 2023 Mar; 64(3): 8. Published online 2023 Mar 3. doi: 10.1167/iovs.64.3.8

PMCID:: PMC9988703

Abstract Article PDF–13M

Select item 97399678.

TGF-β2 Regulates Transcription of the K⁺/Cl⁻ Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

Anastasia Rigkou, Attila Magyar, Jan Manuel Speer, Eleni Roussa

Cells. 2022 Dec; 11(23): 3861. Published online 2022 Nov 30. doi: 10.3390/cells11233861

PMCID:: PMC9739967

Abstract Article PDF–3.4M

Select item 94819759.

Understanding the development of oral epithelial organs through single cell transcriptomic analysis

Qianlin Ye, Arshia Bhojwani, Jimmy K. Hu

Development. 2022 Aug 15; 149(16): dev200539. Published online 2022 Aug 17. doi: 10.1242/dev.200539

PMCID:: PMC9481975

Abstract Article

Select item 938289810.

Single-cell transcriptomic signatures and gene regulatory networks modulated by Wls in mammalian midline facial formation and clefts

Ran Gu, Shuwen Zhang, Subbroto Kumar Saha, Yu Ji, Kurt Reynolds, Moira McMahon, Bo Sun, Mohammad Islam, Paul A. Trainor, YiPing Chen, Ying Xu, Yang Chai, Diana Burkart-Waco, Chengji J. Zhou

Development. 2022 Jul 15; 149(14): dev200533. Published online 2022 Jul 22. doi: 10.1242/dev.200533

PMCID:: PMC9382898

Abstract Article

Select item 938150411.

Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis

Junjun Jing, Jifan Feng, Yuan Yuan, Tingwei Guo, Jie Lei, Fei Pei, Thach-Vu Ho, Yang Chai

Nat Commun. 2022; 13: 4803. Published online 2022 Aug 16. doi: 10.1038/s41467-022-32490-y

PMCID:: PMC9381504

Abstract Article PDF–6.6M

Select item 918875812.

Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis

Kathryn Duvall, Lauren Crist, Alison J. Perl, Naomi Pode Shakked, Praneet Chaturvedi, Raphael Kopan

Development. 2022 May 15; 149(10): dev200446. Published online 2022 May 16. doi: 10.1242/dev.200446

PMCID:: PMC9188758

Abstract Article

Select item 903890613.

Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney

Joseph O. Lamontagne, Hui Zhang, Alia M. Zeid, Karin Strittmatter, Alicia D. Rocha, Trevor Williams, Sheryl Zhang, Alexander G. Marneros

Nat Commun. 2022; 13: 2226. Published online 2022 Apr 25. doi: 10.1038/s41467-022-29644-3

PMCID:: PMC9038906

Abstract Article PDF–15M

Select item 903819714.

AP-2α and AP-2β cooperatively function in the craniofacial surface ectoderm to regulate chromatin and gene expression dynamics during facial development

Eric Van Otterloo, Isaac Milanda, Hamish Pike, Jamie A Thompson, Hong Li, Kenneth L Jones, Trevor Williams

eLife. 2022; 11: e70511. Published online 2022 Mar 25. doi: 10.7554/eLife.70511

PMCID:: PMC9038197

Abstract Article PDF–16M

Select item 896127315.

Deletion of transcription factor AP-2β from the developing murine trabecular meshwork region leads to progressive glaucomatous changes

Aftab Taiyab, Monica Akula, Japnit Dham, Paula Deschamps, Heather Sheardown, Trevor Williams, Teresa Borrás, Judith A. West-Mays

J Neurosci Res. Author manuscript; available in PMC 2022 Mar 29.

Published in final edited form as: J Neurosci Res. 2022 Feb; 100(2): 638–652. Published online 2021 Nov 25. doi: 10.1002/jnr.24982

PMCID:: PMC8961273

Abstract Article PDF–2.5M

Select item 895913916.

Selective requirement for polycomb repressor complex 2 in the generation of specific hypothalamic neuronal subtypes

Behzad Yaghmaeian Salmani, Brad Balderson, Susanne Bauer, Helen Ekman, Annika Starkenberg, Thomas Perlmann, Michael Piper, Mikael Bodén, Stefan Thor

Development. 2022 Mar 1; 149(5): dev200076. Published online 2022 Mar 7. doi: 10.1242/dev.200076

PMCID:: PMC8959139

Abstract Article

Select item 887649617.

Prdm6 controls heart development by regulating neural crest cell differentiation and migration

Lingjuan Hong, Na Li, Victor Gasque, Sameet Mehta, Lupeng Ye, Yinyu Wu, Jinyu Li, Andreas Gewies, Jürgen Ruland, Karen K. Hirschi, Anne Eichmann, Caroline Hendry, David van Dijk, Arya Mani

JCI Insight. 2022 Feb 22; 7(4): e156046. Published online 2022 Feb 22. doi: 10.1172/jci.insight.156046

PMCID:: PMC8876496

Abstract Article PDF–30M

Select item 839577818.

Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification

Haydn Walker, Aftab Taiyab, Paula Deschamps, Trevor Williams, Judith A. West-Mays

Int J Mol Sci. 2021 Aug; 22(16): 8730. Published online 2021 Aug 13. doi: 10.3390/ijms22168730

PMCID:: PMC8395778

Abstract Article PDF–5.1M

Select item 801819319.

Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development

Emily D. Woodruff, Galaxy C. Gutierrez, Eric Van Otterloo, Trevor Williams, Martin J. Cohn

Dev Biol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: Dev Biol. 2021 Apr; 472: 67–74. Published online 2021 Jan 15. doi: 10.1016/j.ydbio.2020.12.017

PMCID:: PMC8018193

Abstract Article PDF–2.6M

Select item 800525720.

AP-2β is Required for Formation of the Murine Trabecular Meshwork and Schlemm’s Canal

Monica Akula, Aftab Taiyab, Paula Deschamps, Shannin Yee, Alexander K. Ball, Trevor Williams, Judith A. West-Mays

Exp Eye Res. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: Exp Eye Res. 2020 Jun; 195: 108042. Published online 2020 Apr 27. doi: 10.1016/j.exer.2020.108042

PMCID:: PMC8005257

Abstract Article PDF–2.2M

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