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Items: 1 to 20 of 50

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
2.
The interaction of Synapsin 2a and Synaptogyrin-3 regulates fear extinction in mice
Xi-Ya Shen, Juan Zhang, He-Zhou Huang, Shao-Dan Li, Ling Zhou, Shi-Ping Wu, Cheng Tang, Xian Huang, Zhi-Qiang Liu, Zi-Yuan Guo, Xiang Li, Heng-Ye Man, You-Ming Lu, Ling-Qiang Zhu, Dan Liu
J Clin Invest. 2024 Feb 15; 134(4): e172802. Published online 2024 Jan 4. doi: 10.1172/JCI172802
PMCID:
PMC10866652
ArticlePDF–4.1M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
ArticlePDF–8.8M
4.
Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes
Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x
PMCID:
PMC9938216
ArticlePDF–5.3M
5.
In vivo overexpression of synaptogyrin‐3 promotes striatal synaptic dopamine uptake in LRRK2R1441G mutant mouse model of Parkinson's disease
Philip Wing‐Lok Ho, Lingfei Li, Hui‐Fang Liu, Zoe Yuen‐Kiu Choi, Eunice Eun Seo Chang, Shirley Yin‐Yu Pang, Yasine Malki, Chi‐Ting Leung, Michelle Hiu‐Wai Kung, David Boyer Ramsden, Shu‐Leong Ho
Brain Behav. 2023 Feb; 13(2): e2886. Published online 2023 Jan 9. doi: 10.1002/brb3.2886
PMCID:
PMC9927849
ArticlePDF–4.4M
6.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
ArticlePDF–1.6M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
8.
Lowering Synaptogyrin-3 expression rescues Tau-induced memory defects and synaptic loss in the presence of microglial activation
Pablo Largo-Barrientos, Nuno Apóstolo, Eline Creemers, Zsuzsanna Callaerts-Vegh, Jef Swerts, Caitlin Davies, Joseph McInnes, Keimpe Wierda, Bart De Strooper, Tara Spires-Jones, Joris de Wit, Valerie Uytterhoeven, Patrik Verstreken
Neuron. 2021 Mar 3; 109(5): 767–777.e5. doi: 10.1016/j.neuron.2020.12.016
PMCID:
PMC7927913
Article
9.
Tuning of Glutamate, But Not GABA, Release by an Intrasynaptic Vesicle APP Domain Whose Function Can Be Modulated by β- or α-Secretase Cleavage
Wen Yao, Marc D. Tambini, Xinran Liu, Luciano D'Adamio
J Neurosci. 2019 Aug 28; 39(35): 6992–7005. doi: 10.1523/JNEUROSCI.0207-19.2019
PMCID:
PMC6733572
ArticlePDF–2.9M
10.
Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts
Mathan K Raja, Julia Preobraschenski, Sergio Del Olmo-Cabrera, Rebeca Martinez-Turrillas, Reinhard Jahn, Isabel Perez-Otano, John F Wesseling
eLife. 2019; 8: e40744. Published online 2019 May 15. doi: 10.7554/eLife.40744
PMCID:
PMC6519982
ArticlePDF–1.5M
11.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
ArticlePDF–5.1M
12.
RNA binding proteins co-localize with small tau inclusions in tauopathy
Brandon F. Maziuk, Daniel J. Apicco, Anna Lourdes Cruz, Lulu Jiang, Peter E. A. Ash, Edroaldo Lummertz da Rocha, Cheng Zhang, Wai Haung Yu, John Leszyk, Jose F. Abisambra, Hu Li, Benjamin Wolozin
Acta Neuropathol Commun. 2018; 6: 71. Published online 2018 Aug 1. doi: 10.1186/s40478-018-0574-5
PMCID:
PMC6069705
ArticlePDF–5.5M
13.
Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid
Leela Rani Avula, Tiane Chen, Olga Kovbasnjuk, Mark Donowitz
Am J Physiol Gastrointest Liver Physiol. 2018 Jan 1; 314(1): G81–G90. Published online 2017 Sep 7. doi: 10.1152/ajpgi.00140.2017
PMCID:
PMC5866371
Article
14.
The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing
Christian Vogl, Tanvi Butola, Natja Haag, Torben J Hausrat, Michael G Leitner, Michel Moutschen, Philippe P Lefèbvre, Carsten Speckmann, Lillian Garrett, Lore Becker, Helmut Fuchs, Martin Hrabe de Angelis, Sandor Nietzsche, Michael M Kessels, Dominik Oliver, Matthias Kneussel, Manfred W Kilimann, Nicola Strenzke
EMBO Rep. 2017 Nov; 18(11): 2015–2029. Published online 2017 Sep 11. doi: 10.15252/embr.201643689
PMCID:
PMC5666617
ArticlePDF–7.3M
15.
Group II Metabotropic Glutamate Receptor Interactions with NHERF Scaffold Proteins: Implications for Receptor Localization in Brain
Stefanie L. Ritter-Makinson, Maryse Paquet, James W. Bogenpohl, Rachel E. Rodin, C. Chris Yun, Edward J. Weinman, Yoland Smith, Randy A. Hall
Neuroscience. Author manuscript; available in PMC 2018 Jun 14.
Published in final edited form as: Neuroscience. 2017 Jun 14; 353: 58–75. Published online 2017 Apr 7. doi: 10.1016/j.neuroscience.2017.03.060
PMCID:
PMC5503475
ArticlePDF–1.0M
16.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
ArticlePDF–1.4M
17.
Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24
Michihiro Yoshida, Luqing Zhao, Gevorg Grigoryan, Hyunsuk Shim, Peijian He, C. Chris Yun
Am J Physiol Gastrointest Liver Physiol. 2016 Apr 15; 310(8): G586–G598. Published online 2016 Feb 11. doi: 10.1152/ajpgi.00419.2015
PMCID:
PMC4836134
Article
18.
The PDZ Scaffold NHERF-2 Interacts with mGluR5 and Regulates Receptor Activity
Maryse Paquet, Matthew J. Asay, Sami R. Fam, Hiroyuki Inuzuka, Amanda M. Castleberry, Heide Oller, Yoland Smith, C. Chris Yun, Stephen F. Traynelis, Randy A. Hall
J Biol Chem. Author manuscript; available in PMC 2015 Dec 6.
Published in final edited form as: J Biol Chem. 2006 Oct 6; 281(40): 29949–29961. Published online 2006 Aug 4. doi: 10.1074/jbc.M602262200
PMCID:
PMC4670778
ArticlePDF–1.1M
19.
Altered cGMP Dynamics at the Plasma Membrane Contribute to Diarrhea in Ulcerative Colitis
Kavisha Arora, Chandrima Sinha, Weiqiang Zhang, Chang Suk Moon, Aixia Ren, Sunitha Yarlagadda, Wolfgang R. Dostmann, Adebowale Adebiyi, Yael Haberman, Lee A. Denson, Xusheng Wang, Anjaparavanda P. Naren
Am J Pathol. 2015 Oct; 185(10): 2790–2804. doi: 10.1016/j.ajpath.2015.06.007
PMCID:
PMC4607763
ArticlePDF–2.2M
20.
Mapping the H+ (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation
Maria Merkulova, Teodor G. Păunescu, Anie Azroyan, Vladimir Marshansky, Sylvie Breton, Dennis Brown
Sci Rep. 2015; 5: 14827. Published online 2015 Oct 7. doi: 10.1038/srep14827
PMCID:
PMC4595830
ArticlePDF–1.5M

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