PMC Links for GEO Profiles (Select 4455211) - PMC

Chun-Guang Guo, Rui Sun, Xiao Wang, Ye Yuan, Yan Xu, Shihan Li, Xueting Sun, Jue Wang, Xinli Hu, Tiannan Guo, Xiao-Wei Chen, Rui-Ping Xiao, Xiuqin Zhang

Mol Metab. 2024 Jan; 79: 101847. Published online 2023 Nov 30. doi: 10.1016/j.molmet.2023.101847

PMCID:: PMC10755498

Abstract Article PDF–3.6M

Select item 102861054.

Acetyl-CoA carboxylase 1 is a suppressor of the adipocyte thermogenic program

Adilson Guilherme, Leslie A. Rowland, Nicole Wetoska, Emmanouela Tsagkaraki, Kaltinaitis B. Santos, Alexander H. Bedard, Felipe Henriques, Mark Kelly, Sean Munroe, David J. Pedersen, Olga R. Ilkayeva, Timothy R. Koves, Lauren Tauer, Meixia Pan, Xianlin Han, Jason K. Kim, Christopher B. Newgard, Deborah M. Muoio, Michael P. Czech

Cell Rep. Author manuscript; available in PMC 2023 Jun 22.

Published in final edited form as: Cell Rep. 2023 May 30; 42(5): 112488. Published online 2023 May 8. doi: 10.1016/j.celrep.2023.112488

PMCID:: PMC10286105

Abstract Article PDF–3.3M

Select item 102058625.

Involvement of ACACA (acetyl-CoA carboxylase α) in the lung pre-metastatic niche formation in breast cancer by senescence phenotypic conversion in fibroblasts

Yung-Chi Huang, Ming-Feng Hou, Ying-Ming Tsai, Yi-Chung Pan, Pei-Hsun Tsai, Yi-Shiuan Lin, Chao-Yuan Chang, Eing-Mei Tsai, Ya-Ling Hsu

Cell Oncol (Dordr) 2023; 46(3): 643–660. Published online 2023 Jan 6. doi: 10.1007/s13402-022-00767-5

PMCID:: PMC10205862

Abstract Article PDF–11M

Select item 96837126.

Macrophage acetyl-CoA carboxylase regulates acute inflammation through control of glucose and lipid metabolism

Scott Yeudall, Clint M. Upchurch, Philip V. Seegren, Caitlin M. Pavelec, Jan Greulich, Michael C. Lemke, Thurl E. Harris, Bimal N. Desai, Kyle L. Hoehn, Norbert Leitinger

Sci Adv. 2022 Nov; 8(47): eabq1984. Published online 2022 Nov 23. doi: 10.1126/sciadv.abq1984

PMCID:: PMC9683712

Abstract Article PDF–2.7M

Select item 94819337.

ALS-linked loss of Cyclin-F function affects HSP90

Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends

Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359

PMCID:: PMC9481933

Abstract Article PDF–3.5M

Select item 93864648.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 89334129.

Acetyl-CoA-carboxylase 1 (ACC1) plays a critical role in glucagon secretion

Anna Veprik, Geoffrey Denwood, Dong Liu, Rula Bany Bakar, Valentin Morfin, Kara McHugh, Nchimunya N. Tebeka, Laurène Vetterli, Ekaterina Yonova-Doing, Fiona Gribble, Frank Reimann, Kyle L. Hoehn, Piers A. Hemsley, Jonas Ahnfelt-Rønne, Patrik Rorsman, Quan Zhang, Heidi de Wet, James Cantley

Commun Biol. 2022; 5: 238. Published online 2022 Mar 18. doi: 10.1038/s42003-022-03170-w

PMCID:: PMC8933412

Abstract Article PDF–2.2M

Select item 861415710.

ACC1-expressing pathogenic T helper 2 cell populations facilitate lung and skin inflammation in mice

Takahiro Nakajima, Toshio Kanno, Satoru Yokoyama, Shigemi Sasamoto, Hikari K. Asou, Damon J. Tumes, Osamu Ohara, Toshinori Nakayama, Yusuke Endo

J Exp Med. 2021 Dec 6; 218(12): e20210639. Published online 2021 Nov 23. doi: 10.1084/jem.20210639

PMCID:: PMC8614157

Abstract Article PDF–8.6M

Select item 824202311.

SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4⁺ T cells

Toshio Kanno, Takahiro Nakajima, Satoru Yokoyama, Hikari K. Asou, Shigemi Sasamoto, Yasuhiro Kamii, Koji Hayashizaki, Yasuo Ouchi, Taishi Onodera, Yoshimasa Takahashi, Kazutaka Ikeda, Yoshinori Hasegawa, Yuki Kinjo, Osamu Ohara, Toshinori Nakayama, Yusuke Endo

Commun Biol. 2021; 4: 820. Published online 2021 Jun 29. doi: 10.1038/s42003-021-02310-y

PMCID:: PMC8242023

Abstract Article PDF–3.7M

Select item 820345312.

Stabilization of fatty acid synthesis enzyme acetyl-CoA carboxylase 1 suppresses acute myeloid leukemia development

Hidenori Ito, Ikuko Nakamae, Jun-ya Kato, Noriko Yoneda-Kato

J Clin Invest. 2021 Jun 15; 131(12): e141529. Published online 2021 Jun 15. doi: 10.1172/JCI141529

PMCID:: PMC8203453

Abstract Article PDF–8.8M

Select item 778845413.

AMPK regulates cell shape of cardiomyocytes by modulating turnover of microtubules through CLIP‐170

Shohei Yashirogi, Takemasa Nagao, Yuya Nishida, Yusuke Takahashi, Tasneem Qaqorh, Issei Yazawa, Toru Katayama, Hidetaka Kioka, Tsubasa S Matsui, Shigeyoshi Saito, Yuki Masumura, Osamu Tsukamoto, Hisakazu Kato, Hiromichi Ueda, Osamu Yamaguchi, Kenta Yashiro, Satoru Yamazaki, Seiji Takashima, Yasunori Shintani

EMBO Rep. 2021 Jan 7; 22(1): e50949. Published online 2020 Nov 29. doi: 10.15252/embr.202050949

PMCID:: PMC7788454

Abstract Article PDF–2.4M

Select item 698673014.

Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitis

Mitsuharu Matsumoto, Hiroaki Yashiro, Hitomi Ogino, Kazunobu Aoyama, Tadahiro Nambu, Sayuri Nakamura, Mayumi Nishida, Xiaolun Wang, Derek M. Erion, Manami Kaneko

PLoS One. 2020; 15(1): e0228212. Published online 2020 Jan 28. doi: 10.1371/journal.pone.0228212

PMCID:: PMC6986730

Abstract Article PDF–2.7M

Select item 664329715.

Inhibition of acetyl-CoA carboxylase (ACC) by phosphorylation or by the liver-specific inhibitor, ND-654, suppresses lipogenesis and hepatocellular carcinoma

James S.V. Lally, Sarani Ghoshal, Danielle K. DePeralta, Omeed Moaven, Lan Wei, Ricard Masia, Derek J. Erstad, Naoto Fujiwara, Vivian Leong, Vanessa P. Houde, Alexander E. Anagnostopoulos, Alice Wang, Lindsay A. Broadfield, Rebecca J. Ford, Robert A. Foster, Jamie Bates, Hailing Sun, Ting Wang, Henry Liu, Adrian S. Ray, Asish K. Saha, Jeremy Greenwood, Sathesh Bhat, Geraldine Harriman, Wenyan Miao, Jennifer L. Rocnik, William F. Westlin, Paola Muti, Theodoros Tsakiridis, H. James Harwood, Jr, Rosana Kapeller, Yujin Hoshida, Kenneth K. Tanabe, Gregory R. Steinberg, Bryan C. Fuchs

Cell Metab. Author manuscript; available in PMC 2020 Jan 8.

Published in final edited form as: Cell Metab. 2019 Jan 8; 29(1): 174–182.e5. Published online 2018 Sep 20. doi: 10.1016/j.cmet.2018.08.020

PMCID:: PMC6643297

Abstract Article PDF–1.1M

Select item 662067116.

Acetyl-CoA carboxylase inhibition regulates microtubule dynamics and intracellular transport in cystic fibrosis epithelial cells

Sharon M. Rymut, Binyu Lu, Aura Perez, Deborah A. Corey, Kata Lamb, Calvin U. Cotton, Thomas J. Kelley

Am J Physiol Lung Cell Mol Physiol. 2019 Jun 1; 316(6): L1081–L1093. Published online 2019 Mar 20. doi: 10.1152/ajplung.00369.2018

PMCID:: PMC6620671

Abstract Article

Select item 651836817.

Adipocyte STAT5 deficiency promotes adiposity and impairs lipid mobilisation in mice

Doris Kaltenecker, Kristina M. Mueller, Pia Benedikt, Ursula Feiler, Madeleine Themanns, Michaela Schlederer, Lukas Kenner, Martina Schweiger, Guenter Haemmerle, Richard Moriggl

Diabetologia. 2017; 60(2): 296–305. Published online 2016 Nov 17. doi: 10.1007/s00125-016-4152-8

PMCID:: PMC6518368

Abstract Article PDF–1.3M

Select item 635149918.

A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis

Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang, Saverio Bellusci

Front Genet. 2018; 9: 746. Published online 2019 Jan 23. doi: 10.3389/fgene.2018.00746

PMCID:: PMC6351499

Abstract Article PDF–5.6M

Select item 629804019.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

Select item 629073120.

Disruption of beta cell acetyl-CoA carboxylase-1 in mice impairs insulin secretion and beta cell mass

James Cantley, Aimee Davenport, Laurène Vetterli, Nandor J. Nemes, P. Tess Whitworth, Ebru Boslem, Le May Thai, Natalie Mellett, Peter J. Meikle, Kyle L. Hoehn, David E. James, Trevor J. Biden

Diabetologia. 2019; 62(1): 99–111. Published online 2018 Oct 17. doi: 10.1007/s00125-018-4743-7

PMCID:: PMC6290731

Abstract Article PDF–1.2M

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