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Select item 113659541.

Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation

Vaishali N. Patel, Marit H. Aure, Sophie H. Choi, James R. Ball, Ethan D. Lane, Zhangjie Wang, Yongmei Xu, Changyu Zheng, Xibao Liu, Daniel Martin, Jillian Y. Pailin, Michaela Prochazkova, Ashok B. Kulkarni, Toin H. van Kuppevelt, Indu S. Ambudkar, Jian Liu, Matthew P. Hoffman

Nat Commun. 2024; 15: 7584. Published online 2024 Aug 31. doi: 10.1038/s41467-024-51862-0

Correction in:: Nat Commun. 2024; 15: 8784.

PMCID:: PMC11365954

Abstract Article PDF–5.0M

Select item 109076432.

Activation of goblet-cell stress sensor IRE1β is controlled by the mucin chaperone AGR2

Eva Cloots, Phaedra Guilbert, Mathias Provost, Lisa Neidhardt, Evelien Van de Velde, Farzaneh Fayazpour, Delphine De Sutter, Savvas N Savvides, Sven Eyckerman, Sophie Janssens

EMBO J. 2024 Mar; 43(5): 695–718. Published online 2023 Dec 20. doi: 10.1038/s44318-023-00015-y

PMCID:: PMC10907643

Abstract Article PDF–4.4M

Select item 98057533.

Agr2-associated ER stress promotes adherent-invasive E. coli dysbiosis and triggers CD103⁺ dendritic cell IL-23-dependent ileocolitis

Monica Viladomiu, Manirath Khounlotham, Belgin Dogan, Svetlana F. Lima, Ahmed Elsaadi, Emre Cardakli, Jim G. Castellanos, Charles Ng, Jeremy Herzog, Alexi A. Schoenborn, Melissa Ellermann, Bo Liu, Shiying Zhang, Ajay S. Gulati, R. Balfour Sartor, Kenneth W. Simpson, Steven M. Lipkin, Randy S. Longman

Cell Rep. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Cell Rep. 2022 Nov 15; 41(7): 111637. doi: 10.1016/j.celrep.2022.111637

PMCID:: PMC9805753

Abstract Article PDF–2.4M

Select item 85512174.

Human AGR2 Deficiency Causes Mucus Barrier Dysfunction and Infantile Inflammatory Bowel Disease

Ahmad A. Al-Shaibi, Ussama M. Abdel-Motal, Satanay Z. Hubrack, Alex N. Bullock, Amna A. Al-Marri, Nourhen Agrebi, Abdulrahman A. Al-Subaiey, Nazira A. Ibrahim, Adrian K. Charles, COLORS in IBD-Qatar Study Group, Mamoun Elawad, Holm H. Uhlig, Bernice Lo

Cell Mol Gastroenterol Hepatol. 2021; 12(5): 1809–1830. Published online 2021 Jul 6. doi: 10.1016/j.jcmgh.2021.07.001

Correction in:: Cell Mol Gastroenterol Hepatol. 2024; 17(4): 670.

PMCID:: PMC8551217

Abstract Article PDF–17M

Select item 79757085.

Anterior gradient 2 increases long-chain fatty acid uptake via stabilizing FABP1 and facilitates lipid accumulation

Yunqiu Wang, Mengqi Jia, Chuanjie Liang, Nan Sheng, Xiaodan Wang, Fang Wang, Yanhai Luo, Jin Jiang, Liangyu Cai, Huanmin Niu, Deyu Zhu, Effat Un Nesa, Charles YF Young, Huiqing Yuan

Int J Biol Sci. 2021; 17(3): 834–847. Published online 2021 Feb 8. doi: 10.7150/ijbs.57099

PMCID:: PMC7975708

Abstract Article PDF–4.0M

Select item 69260516.

WNT/RYK signaling restricts goblet cell differentiation during lung development and repair

Hyun-Taek Kim, Wenguang Yin, Yuko Nakamichi, Paolo Panza, Beate Grohmann, Carmen Buettner, Stefan Guenther, Clemens Ruppert, Yasuhiro Kobayashi, Andreas Guenther, Didier Y. R. Stainier

Proc Natl Acad Sci U S A. 2019 Dec 17; 116(51): 25697–25706. Published online 2019 Nov 27. doi: 10.1073/pnas.1911071116

PMCID:: PMC6926051

Abstract Article PDF–2.9M

Select item 68445637.

Paracrine signalling of AGR2 stimulates RhoA function in fibroblasts and modulates cell elongation and migration

Hitesh Bhagavanbhai Mangukiya, Hema Negi, Siva Bharath Merugu, Qudsia Sehar, Dhahiri Saidi Mashausi, Fakhar-Un-Nisa Yunus, Zhenghua Wu, Dawei Li

Cell Adh Migr. 2019; 13(1): 332–344. Published online 2019 Nov 11. doi: 10.1080/19336918.2019.1685928

PMCID:: PMC6844563

Abstract Article PDF–2.2M

Select item 65546698.

Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation

Marion Maurel, Joanna Obacz, Tony Avril, Yong‐Ping Ding, Olga Papadodima, Xavier Treton, Fanny Daniel, Eleftherios Pilalis, Johanna Hörberg, Wenyang Hou, Marie‐Claude Beauchamp, Julien Tourneur‐Marsille, Dominique Cazals‐Hatem, Lucia Sommerova, Afshin Samali, Jan Tavernier, Roman Hrstka, Aurélien Dupont, Delphine Fessart, Frédéric Delom, Martin E Fernandez‐Zapico, Gregor Jansen, Leif A Eriksson, David Y Thomas, Loydie Jerome‐Majewska, Ted Hupp, Aristotelis Chatziioannou, Eric Chevet, Eric Ogier‐Denis

EMBO Mol Med. 2019 Jun; 11(6): e10120. Published online 2019 Apr 30. doi: 10.15252/emmm.201810120

PMCID:: PMC6554669

Abstract Article PDF–3.4M

Select item 54670159.

ER stress protein AGR2 precedes and is involved in the regulation of pancreatic cancer initiation

L Dumartin, W Alrawashdeh, S M Trabulo, T P Radon, K Steiger, R M Feakins, M P di Magliano, C Heeschen, I Esposito, N R Lemoine, T Crnogorac-Jurcevic

Oncogene. 2017 Jun 1; 36(22): 3094–3103. Published online 2016 Dec 12. doi: 10.1038/onc.2016.459

PMCID:: PMC5467015

Abstract Article PDF–3.5M

Select item 507274210.

Anterior Gradient 2 (AGR2) Induced Epidermal Growth Factor Receptor (EGFR) Signaling Is Essential for Murine Pancreatitis-Associated Tissue Regeneration

Dariusz Wodziak, Aiwen Dong, Michael F. Basin, Anson W. Lowe

PLoS One. 2016; 11(10): e0164968. Published online 2016 Oct 20. doi: 10.1371/journal.pone.0164968

PMCID:: PMC5072742

Abstract Article PDF–2.9M

Select item 474289511.

The Endoplasmic Reticulum Resident Protein AGR3. Required for Regulation of Ciliary Beat Frequency in the Airway

Luke R. Bonser, Bradley W. Schroeder, Lisa A. Ostrin, Nathalie Baumlin, Jean L. Olson, Matthias Salathe, David J. Erle

Am J Respir Cell Mol Biol. 2015 Oct; 53(4): 536–543. doi: 10.1165/rcmb.2014-0318OC

PMCID:: PMC4742895

Abstract Article PDF–1.2M

Select item 437545912.

Epidermal Growth Factor Receptor (EGFR) Signaling Requires a Specific Endoplasmic Reticulum Thioredoxin for the Post-translational Control of Receptor Presentation to the Cell Surface

Aiwen Dong, Dariusz Wodziak, Anson W. Lowe

J Biol Chem. 2015 Mar 27; 290(13): 8016–8027. Published online 2015 Feb 9. doi: 10.1074/jbc.M114.623207

PMCID:: PMC4375459

Abstract Article PDF–3.2M

Select item 422227913.

Lung mesenchymal expression of Sox9 plays a critical role in tracheal development

Gianluca Turcatel, Nicole Rubin, Douglas B Menke, Gary Martin, Wei Shi, David Warburton

BMC Biol. 2013; 11: 117. Published online 2013 Nov 25. doi: 10.1186/1741-7007-11-117

PMCID:: PMC4222279

Abstract Article PDF–4.9M

Select item 412865914.

AGR2, an Endoplasmic Reticulum Protein, Is Secreted into the Gastrointestinal Mucus

Joakim H. Bergström, Katarina A. Berg, Ana M. Rodríguez-Piñeiro, Bärbel Stecher, Malin E. V. Johansson, Gunnar C. Hansson

PLoS One. 2014; 9(8): e104186. Published online 2014 Aug 11. doi: 10.1371/journal.pone.0104186

PMCID:: PMC4128659

Abstract Article PDF–5.4M

Select item 362564415.

Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm

Jianwen Que, Tadashi Okubo, James R. Goldenring, Ki-Taek Nam, Reiko Kurotani, Edward E. Morrisey, Olena Taranova, Larysa H. Pevny, Brigid L. M. Hogan

Development. Author manuscript; available in PMC 2013 Apr 14.

Published in final edited form as: Development. 2007 Jul; 134(13): 2521–2531. Published online 2007 May 23. doi: 10.1242/dev.003855

PMCID:: PMC3625644

Abstract Article PDF–3.0M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163