PMC Links for GEO Profiles (Select 44236304) - PMC

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Items: 14

Select item 109409291.

Dysregulated lysosomal exocytosis drives protease-mediated cartilage pathogenesis in multiple lysosomal disorders

Jen-Jie Lee, Tong Wang, Kali Wiggins, Po Nien Lu, Christina Underwood, Katarzyna Ochenkowska, Eric Samarut, Laura M. Pollard, Heather Flanagan-Steet, Richard Steet

iScience. 2024 Apr 19; 27(4): 109293. Published online 2024 Feb 21. doi: 10.1016/j.isci.2024.109293

PMCID:: PMC10940929

Article PDF–5.5M

Select item 102682542.

ROS signaling–induced mitochondrial Sgk1 expression regulates epithelial cell renewal

Yingxiang Li, Chengdong Liu, Luke Rolling, Veronica Sikora, Zhimin Chen, Jack Gurwin, Caroline Barabell, Jiandie Lin, Cunming Duan

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2216310120. Published online 2023 Jun 5. doi: 10.1073/pnas.2216310120

PMCID:: PMC10268254

Article PDF–3.6M

Select item 94683373.

GCAF(TMEM251) regulates lysosome biogenesis by activating the mannose-6-phosphate pathway

Weichao Zhang, Xi Yang, Yingxiang Li, Linchen Yu, Bokai Zhang, Jianchao Zhang, Woo Jung Cho, Varsha Venkatarangan, Liang Chen, Bala Bharathi Burugula, Sarah Bui, Yanzhuang Wang, Cunming Duan, Jacob O. Kitzman, Ming Li

Nat Commun. 2022; 13: 5351. Published online 2022 Sep 12. doi: 10.1038/s41467-022-33025-1

PMCID:: PMC9468337

Article PDF–5.1M

Select item 76055274.

Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation

Po-Nien Lu, Trevor Moreland, Courtney J. Christian, Troy C. Lund, Richard A. Steet, Heather Flanagan-Steet

JCI Insight. 2020 Oct 15; 5(20): e133019. Published online 2020 Oct 15. doi: 10.1172/jci.insight.133019

PMCID:: PMC7605527

Article PDF–25M

Select item 49491395.

Enzyme-Specific Differences in Mannose Phosphorylation Between GlcNAc-1-Phosphotransferase αβ and γ subunit Deficient Zebrafish Support Cathepsin Proteases As Early Mediators of Mucolipidosis Pathology

Heather Flanagan-Steet, Courtney Matheny, Aaron Petrey, Joshua Parker, Richard Steet

Biochim Biophys Acta. Author manuscript; available in PMC 2017 Sep 1.

Published in final edited form as: Biochim Biophys Acta. 2016 Sep; 1860(9): 1845–1853. Published online 2016 May 27. doi: 10.1016/j.bbagen.2016.05.029

PMCID:: PMC4949139

Article PDF–2.5M

Select item 48707326.

Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database

Jeremy Pasquier, Cédric Cabau, Thaovi Nguyen, Elodie Jouanno, Dany Severac, Ingo Braasch, Laurent Journot, Pierre Pontarotti, Christophe Klopp, John H. Postlethwait, Yann Guiguen, Julien Bobe

BMC Genomics. 2016; 17: 368. Published online 2016 May 18. doi: 10.1186/s12864-016-2709-z

PMCID:: PMC4870732

Article PDF–1.8M

Select item 48084927.

Cathepsin-Mediated Alterations in TGFß-Related Signaling Underlie Disrupted Cartilage and Bone Maturation Associated With Impaired Lysosomal Targeting

Heather Flanagan-Steet, Megan Aarnio, Brian Kwan, Pierre Guihard, Aaron Petrey, Mark Haskins, Frederic Blanchard, Richard Steet

J Bone Miner Res. Author manuscript; available in PMC 2016 Sep 1.

Published in final edited form as: J Bone Miner Res. 2016 Mar; 31(3): 535–548. Published online 2015 Oct 13. doi: 10.1002/jbmr.2722

PMCID:: PMC4808492

Article PDF–1.3M

Select item 46341378.

RFX transcription factors are essential for hearing in mice

Ran Elkon, Beatrice Milon, Laura Morrison, Manan Shah, Sarath Vijayakumar, Manoj Racherla, Carmen C. Leitch, Lorna Silipino, Shadan Hadi, Michèle Weiss-Gayet, Emmanuèle Barras, Christoph D. Schmid, Aouatef Ait-Lounis, Ashley Barnes, Yang Song, David J. Eisenman, Efrat Eliyahu, Gregory I. Frolenkov, Scott E. Strome, Bénédicte Durand, Norann A. Zaghloul, Sherri M. Jones, Walter Reith, Ronna Hertzano

Nat Commun. 2015; 6: 8549. Published online 2015 Oct 15. doi: 10.1038/ncomms9549