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Select item 110272201.

UBE2C promotes the proliferation of acute myeloid leukemia cells through PI3K/AKT activation

Li Wang, Shuqin Zhao, Yongling Wang, Jianying Liu, Xiaoli Wang

BMC Cancer. 2024; 24: 497. Published online 2024 Apr 18. doi: 10.1186/s12885-024-12212-x

PMCID:: PMC11027220

Abstract Article PDF–4.2M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108394483.

The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development

Tomoyuki Yamanaka, Masaru Kurosawa, Aya Yoshida, Tomomi Shimogori, Akiko Hiyama, Sankar N. Maity, Nobutaka Hattori, Hideaki Matsui, Nobuyuki Nukina

J Biol Chem. 2024 Feb; 300(2): 105629. Published online 2024 Jan 8. doi: 10.1016/j.jbc.2024.105629

PMCID:: PMC10839448

Abstract Article PDF–5.2M

Select item 99279334.

The UBE2C/CDH1/DEPTOR axis is an oncogene and tumor suppressor cascade in lung cancer cells

Shizhen Zhang, Xiahong You, Yawen Zheng, Yanwen Shen, Xiufang Xiong, Yi Sun

J Clin Invest. 2023 Feb 15; 133(4): e162434. Published online 2023 Feb 15. doi: 10.1172/JCI162434

PMCID:: PMC9927933

Abstract Article PDF–11M

Select item 95591745.

Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states

Huikai Liu, Liwen He, Qianyu Cheng, Wenping Luo, Tianyu Zhao, Deqin Yang

Int J Mol Med. 2022 Nov; 50(5): 132. Published online 2022 Sep 5. doi: 10.3892/ijmm.2022.5188

PMCID:: PMC9559174

Abstract Article PDF–2.9M

Select item 90185846.

Gag‐like proteins: Novel mediators of prenatal alcohol exposure in neural development

Marisa R. Pinson, Dae D. Chung, Amanda H. Mahnke, Nihal A. Salem, Daniel Osorio, Vijay Nair, Elizabeth A. Payne, Jonathan J. del Real, James J. Cai, Rajesh C. Miranda

Alcohol Clin Exp Res. 2022 Apr; 46(4): 556–569. Published online 2022 Mar 2. doi: 10.1111/acer.14796

PMCID:: PMC9018584

Abstract Article PDF–1.8M

Select item 90063337.

Molecular Logic of Cellular Diversification in the Mouse Cerebral Cortex

Daniela J. Di Bella, Ehsan Habibi, Robert R. Stickels, Gabriele Scalia, Juliana Brown, Payman Yadollahpour, Sung Min Yang, Catherine Abbate, Tommasso Biancalani, Evan Z. Macosko, Fei Chen, Aviv Regev, Paola Arlotta

Nature. Author manuscript; available in PMC 2022 Apr 13.

Published in final edited form as: Nature. 2021 Jul; 595(7868): 554–559. Published online 2021 Jun 23. doi: 10.1038/s41586-021-03670-5

Correction in:: Nature. 2021 Aug 2

PMCID:: PMC9006333

Abstract Article PDF–7.2M

Select item 88879038.

Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain

Dongjin R Lee, Christopher Rhodes, Apratim Mitra, Yajun Zhang, Dragan Maric, Ryan K Dale, Timothy J Petros

eLife. 2022; 11: e71864. Published online 2022 Feb 17. doi: 10.7554/eLife.71864

PMCID:: PMC8887903

Abstract Article PDF–15M

Select item 82822419.

Single‐cell RNA‐Seq reveals a highly coordinated transcriptional program in mouse germ cells during primordial follicle formation

Yuanlin He, Qiuzhen Chen, Juncheng Dai, Yiqiang Cui, Chi Zhang, Xidong Wen, Jiazhao Li, Yue Xiao, Xiaoxu Peng, Mingxi Liu, Bin Shen, Jiahao Sha, Zhibin Hu, Jing Li, Wenjie Shu

Aging Cell. 2021 Jul; 20(7): e13424. Published online 2021 Jun 26. doi: 10.1111/acel.13424

PMCID:: PMC8282241

Abstract Article PDF–3.6M

Select item 741599110.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 550326111.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 529582112.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 461808613.

The Interleukin-2-mTORc1 Axis Defines the Reciprocal Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells

John P. Ray, Matthew M. Staron, Justin A. Shyer, Ping-Chih Ho, Heather D. Marshall, Simon M. Gray, Brian J. Laidlaw, Koichi Araki, Rafi Ahmed, Susan M. Kaech, Joe Craft

Immunity. Author manuscript; available in PMC 2016 Oct 20.

Published in final edited form as: Immunity. 2015 Oct 20; 43(4): 690–702. Published online 2015 Sep 22. doi: 10.1016/j.immuni.2015.08.017

PMCID:: PMC4618086

Abstract Article PDF–2.2M

Select item 422368314.

UbcH10 overexpression increases carcinogenesis and blocks ALLN susceptibility in colorectal cancer

Shang-Ze Li, Yang Song, Hui-Hui Zhang, Bing-Xue Jin, Yi Liu, Wen-Bin Liu, Xiao-Dong Zhang, Run-Lei Du

Sci Rep. 2014; 4: 6910. Published online 2014 Nov 7. doi: 10.1038/srep06910

PMCID:: PMC4223683

Abstract Article PDF–1.5M

Select item 396495515.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298946118.

Systematic Characterization of Human Protein Complexes Identifies Chromosome Segregation Proteins

James R.A. Hutchins, Yusuke Toyoda, Björn Hegemann, Ina Poser, Jean-Karim Hériché, Martina M. Sykora, Martina Augsburg, Otto Hudecz, Bettina A. Buschhorn, Jutta Bulkescher, Christian Conrad, David Comartin, Alexander Schleiffer, Mihail Sarov, Andrei Pozniakovsky, Mikolaj Michal Slabicki, Siegfried Schloissnig, Ines Steinmacher, Marit Leuschner, Andrea Ssykor, Steffen Lawo, Laurence Pelletier, Holger Stark, Kim Nasmyth, Jan Ellenberg, Richard Durbin, Frank Buchholz, Karl Mechtler, Anthony A. Hyman, Jan-Michael Peters

Science. Author manuscript; available in PMC 2010 Nov 22.

Published in final edited form as: Science. 2010 Apr 30; 328(5978): 593–599. Published online 2010 Apr 1. doi: 10.1126/science.1181348

PMCID:: PMC2989461

Abstract Article PDF–2.2M

Select item 281285719.

Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation

Janine H. van Ree, Karthik B. Jeganathan, Liviu Malureanu, Jan M. van Deursen

J Cell Biol. 2010 Jan 11; 188(1): 83–100. doi: 10.1083/jcb.200906147

PMCID:: PMC2812857

Abstract Article PDF–9.3M

Select item 255627020.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Abstract Article PDF–493K

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