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Items: 1 to 20 of 68

1.
Microglial CD2AP deficiency exerts protection in an Alzheimer’s disease model of amyloidosis
Lingliang Zhang, Lingling Huang, Yuhang Zhou, Jian Meng, Liang Zhang, Yunqiang Zhou, Naizhen Zheng, Tiantian Guo, Shanshan Zhao, Zijie Wang, Yuanhui Huo, Yingjun Zhao, Xiao-fen Chen, Honghua Zheng, David M. Holtzman, Yun-wu Zhang
Mol Neurodegener. 2024; 19: 95. Published online 2024 Dec 18. doi: 10.1186/s13024-024-00789-7
PMCID:
PMC11658232
ArticlePDF–8.5M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
ArticlePDF–4.8M
3.
Identification and analysis of key circRNAs in the mouse embryonic ovary provides insight into primordial follicle development
Xiangyan Wang, Yan Zhang, Jianjie Yu, Yabo Ma, Yaxiu Xu, Jiaqi Shi, Zhipeng Qi, Xinfeng Liu
BMC Genomics. 2024; 25: 139. Published online 2024 Feb 3. doi: 10.1186/s12864-024-10058-y
PMCID:
PMC10837906
ArticlePDF–7.1M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
ArticlePDF–2.0M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
ArticlePDF–2.0M
6.
Upregulation of RIN3 induces endosomal dysfunction in Alzheimer’s disease
Ruinan Shen, Xiaobei Zhao, Lu He, Yongbo Ding, Wei Xu, Suzhen Lin, Savannah Fang, Wanlin Yang, Kijung Sung, Brian Spencer, Robert A. Rissman, Ming Lei, Jianqing Ding, Chengbiao Wu
Transl Neurodegener. 2020; 9: 26. Published online 2020 Jun 18. doi: 10.1186/s40035-020-00206-1
PMCID:
PMC7301499
ArticlePDF–14M
7.
Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease
Ravi S. Pandey, Leah Graham, Asli Uyar, Christoph Preuss, Gareth R. Howell, Gregory W. Carter
Mol Neurodegener. 2019; 14: 50. Published online 2019 Dec 26. doi: 10.1186/s13024-019-0351-3
PMCID:
PMC6933917
ArticlePDF–2.2M
8.
A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells
Andrew S. Potter, Keri Drake, Eric W. Brunskill, S. Steven Potter
PLoS One. 2019; 14(8): e0216261. Published online 2019 Aug 28. doi: 10.1371/journal.pone.0216261
PMCID:
PMC6713350
ArticlePDF–2.5M
9.
cindr, the Drosophila Homolog of the CD2AP Alzheimer’s Disease Risk Gene, Is Required for Synaptic Transmission and Proteostasis
Shamsideen A. Ojelade, Tom V. Lee, Nikolaos Giagtzoglou, Lei Yu, Berrak Ugur, Yarong Li, Lita Duraine, Zhongyuan Zuo, Vlad Petyuk, Philip L. De Jager, David A. Bennett, Benjamin R. Arenkiel, Hugo J. Bellen, Joshua M. Shulman
Cell Rep. Author manuscript; available in PMC 2019 Aug 21.
Published in final edited form as: Cell Rep. 2019 Aug 13; 28(7): 1799–1813.e5. doi: 10.1016/j.celrep.2019.07.041
PMCID:
PMC6703184
ArticlePDF–2.4M
10.
Foxc2 is essential for podocyte function
Daniel Nilsson, Mikael Heglind, Zahra Arani, Sven Enerbäck
Physiol Rep. 2019 May; 7(9): e14083. Published online 2019 May 6. doi: 10.14814/phy2.14083
PMCID:
PMC6503019
ArticlePDF–15M
11.
CD2‐Associated Protein Contributes to Hepatitis C, Virus Propagation and Steatosis by Disrupting Insulin Signaling
Huixia Zhang, Chao Zhang, Hong Tang, Shanshan Gao, Fang Sun, Yuan Yang, Weiping Zhou, Yu Hu, Changshu Ke, Yu Wu, Zeyang Ding, Lin Guo, Rongjuan Pei, Xinwen Chen, Man‐Sun Sy, Bixiang Zhang, Chaoyang Li
Hepatology. 2018 Nov; 68(5): 1710–1725. Published online 2018 Oct 27. doi: 10.1002/hep.30073
PMCID:
PMC6220802
ArticlePDF–1.3M
12.
Ultrastructural Characterization of the Glomerulopathy in Alport Mice by Helium Ion Scanning Microscopy (HIM)
Kenji Tsuji, Hani Suleiman, Jeffrey H. Miner, James M. Daley, Diane E. Capen, Teodor G. Păunescu, Hua A. Jenny Lu
Sci Rep. 2017; 7: 11696. Published online 2017 Sep 15. doi: 10.1038/s41598-017-12064-5
PMCID:
PMC5601433
ArticlePDF–3.4M
13.
Inhibition of SHIP2 in CD2AP-deficient podocytes ameliorates reactive oxygen species generation but aggravates apoptosis
Pauliina Saurus, Tuomas A. Tolvanen, Sonja Lindfors, Sara Kuusela, Harry Holthöfer, Eero Lehtonen, Sanna Lehtonen
Sci Rep. 2017; 7: 10731. Published online 2017 Sep 6. doi: 10.1038/s41598-017-10512-w
PMCID:
PMC5587593
ArticlePDF–3.4M
14.
Re-characterization of the Glomerulopathy in CD2AP Deficient Mice by High-Resolution Helium Ion Scanning Microscopy
Kenji Tsuji, Teodor G. Păunescu, Hani Suleiman, Dongping Xie, Fahmy A. Mamuya, Jeffrey H. Miner, Hua A. Jenny Lu
Sci Rep. 2017; 7: 8321. Published online 2017 Aug 16. doi: 10.1038/s41598-017-08304-3
PMCID:
PMC5559584
ArticlePDF–3.7M
15.
CIN85 Deficiency Prevents Nephrin Endocytosis and Proteinuria in Diabetes
Beina Teng, Patricia Schroder, Janina Müller-Deile, Heiko Schenk, Lynne Staggs, Irini Tossidou, Ivan Dikic, Hermann Haller, Mario Schiffer
Diabetes. 2016 Dec; 65(12): 3667–3679. Published online 2016 Aug 16. doi: 10.2337/db16-0081
PMCID:
PMC5314701
ArticlePDF–2.5M
16.
Podocyte injury: the role of proteinuria, urinary plasminogen, and oxidative stress
Leopoldo Raij, Runxia Tian, Jenny S. Wong, John C. He, Kirk N. Campbell
Am J Physiol Renal Physiol. 2016 Dec 1; 311(6): F1308–F1317. Published online 2016 Jun 22. doi: 10.1152/ajprenal.00162.2016
PMCID:
PMC5210206
Article
17.
Bin1 and CD2AP polarise the endocytic generation of beta‐amyloid
Florent Ubelmann, Tatiana Burrinha, Laura Salavessa, Ricardo Gomes, Cláudio Ferreira, Nuno Moreno, Cláudia Guimas Almeida
EMBO Rep. 2017 Jan; 18(1): 102–122. Published online 2016 Nov 28. doi: 10.15252/embr.201642738
PMCID:
PMC5210085
ArticlePDF–4.1M
18.
Loss of endogenous thymosin β4 accelerates glomerular disease
Elisavet Vasilopoulou, Maria Kolatsi-Joannou, Maja T. Lindenmeyer, Kathryn E. White, Michael G. Robson, Clemens D. Cohen, Neil J. Sebire, Paul R. Riley, Paul J. Winyard, David A. Long
Kidney Int. 2016 Nov; 90(5): 1056–1070. doi: 10.1016/j.kint.2016.06.032
PMCID:
PMC5073078
Article
19.
Tankyrase inhibition aggravates kidney injury in the absence of CD2AP
S Kuusela, H Wang, A A Wasik, H Suleiman, S Lehtonen
Cell Death Dis. 2016 Jul; 7(7): e2302. Published online 2016 Jul 21. doi: 10.1038/cddis.2016.217
PMCID:
PMC4973355
ArticlePDF–4.8M
20.
Co‐recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR‐induced ubiquitylation
Guillaume Voisinne, Antonio García‐Blesa, Karima Chaoui, Frédéric Fiore, Elise Bergot, Laura Girard, Marie Malissen, Odile Burlet‐Schiltz, Anne Gonzalez de Peredo, Bernard Malissen, Romain Roncagalli
Mol Syst Biol. 2016 Jul; 12(7): 876. Published online 2016 Jul 29. doi: 10.15252/msb.20166837
PMCID:
PMC4965873
ArticlePDF–1.3M

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