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Items: 1 to 20 of 238

1.
lncRNA Oip5-as1 inhibits excessive mitochondrial fission in myocardial ischemia/reperfusion injury by modulating DRP1 phosphorylation
Xiaowei Niu, Jingjing Zhang, Shuwen Hu, Wenhui Dang, Kaiwen Wang, Ming Bai
Cell Mol Biol Lett. 2024; 29: 72. Published online 2024 May 14. doi: 10.1186/s11658-024-00588-4
PMCID:
PMC11092055
AbstractArticlePDF–15M
2.
MAP4K4 exacerbates cardiac microvascular injury in diabetes by facilitating S-nitrosylation modification of Drp1
Yuqiong Chen, Su Li, Bo Guan, Xiaopei Yan, Chao Huang, Yingqiang Du, Fan Yang, Nannan Zhang, Yafei Li, Jian Lu, Jiankang Wang, Jun Zhang, Zhangwei Chen, Chao Chen, Xiangqing Kong
Cardiovasc Diabetol. 2024; 23: 164. Published online 2024 May 9. doi: 10.1186/s12933-024-02254-7
PMCID:
PMC11084109
AbstractArticlePDF–8.9M
3.
Metabolic and cell cycle shift induced by the deletion of Dnm1l attenuates the dissolution of pluripotency in mouse embryonic stem cells
Bong Jong Seo, Seung Bin Na, Joonhyuk Choi, Byeongyong Ahn, Omer Habib, Chankyu Park, Kwonho Hong, Jeong Tae Do
Cell Mol Life Sci. 2023 Oct; 80(10): 302. Published online 2023 Sep 25. doi: 10.1007/s00018-023-04962-x
PMCID:
PMC11073397
AbstractArticlePDF–4.9M
4.
GSDMD/Drp1 signaling pathway mediates hippocampal synaptic damage and neural oscillation abnormalities in a mouse model of sepsis-associated encephalopathy
Qun Fu, Yi-Bao Zhang, Chang-Xi Shi, Ming Jiang, Kai Lu, Zi-Hui Fu, Jia-Ping Ruan, Jing Wu, Xiao-Ping Gu
J Neuroinflammation. 2024; 21: 96. Published online 2024 Apr 16. doi: 10.1186/s12974-024-03084-w
PMCID:
PMC11020266
AbstractArticlePDF–6.7M
5.
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria
Zhenqi Zhou, Alice Ma, Timothy M. Moore, Dane M. Wolf, Nicole Yang, Peter Tran, Mayuko Segawa, Alexander R. Strumwasser, Wenjuan Ren, Kai Fu, Jonathan Wanagat, Alexander M. van der Bliek, Rachelle Crosbie-Watson, Marc Liesa, Linsey Stiles, Rebecca Acin-Perez, Sushil Mahata, Orian Shirihai, Mark O. Goodarzi, Michal Handzlik, Christian M. Metallo, David W. Walker, Andrea L. Hevener
Sci Adv. 2024 Apr 5; 10(14): eadl0389. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl0389
PMCID:
PMC10990287
AbstractArticlePDF–6.9M
6.
A partial Drp1 knockout improves autophagy flux independent of mitochondrial function
Rebecca Z. Fan, Carolina Sportelli, Yanhao Lai, Said S. Salehe, Jennifer R. Pinnell, Harry J. Brown, Jason R. Richardson, Shouqing Luo, Kim Tieu
Mol Neurodegener. 2024; 19: 26. Published online 2024 Mar 19. doi: 10.1186/s13024-024-00708-w
PMCID:
PMC10953112
AbstractArticlePDF–12M
7.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
8.
Mitochondria-lysosome-related organelles mediate mitochondrial clearance during cellular dedifferentiation
Xiaowen Ma, Sharon Manley, Hui Qian, Yuan Li, Chen Zhang, Kevin Li, Benjamin Ding, Fengli Guo, Allen Chen, Xing Zhang, Meilian Liu, Meihua Hao, Benjamin Kugler, E. Matthew Morris, John Thyfault, Ling Yang, Hiromi Sesaki, Hong-Min Ni, Heidi McBride, Wen-Xing Ding
Cell Rep. Author manuscript; available in PMC 2024 Feb 5.
Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113291. Published online 2023 Oct 19. doi: 10.1016/j.celrep.2023.113291
PMCID:
PMC10842364
AbstractArticlePDF–4.5M
9.
Prostaglandin E2 controls the metabolic adaptation of T cells to the intestinal microenvironment
Matteo Villa, David E. Sanin, Petya Apostolova, Mauro Corrado, Agnieszka M. Kabat, Carmine Cristinzio, Annamaria Regina, Gustavo E. Carrizo, Nisha Rana, Michal A. Stanczak, Francesc Baixauli, Katarzyna M. Grzes, Jovana Cupovic, Francesca Solagna, Alexandra Hackl, Anna-Maria Globig, Fabian Hässler, Daniel J. Puleston, Beth Kelly, Nina Cabezas-Wallscheid, Peter Hasselblatt, Bertram Bengsch, Robert Zeiser, Sagar, Joerg M. Buescher, Edward J. Pearce, Erika L. Pearce
Nat Commun. 2024; 15: 451. Published online 2024 Jan 11. doi: 10.1038/s41467-024-44689-2
PMCID:
PMC10781727
AbstractArticlePDF–3.0M
10.
The fate of mitochondria during platelet activation
Alexei Grichine, Shancy Jacob, Anita Eckly, Joran Villaret, Clotilde Joubert, Florence Appaix, Mylène Pezet, Anne-Sophie Ribba, Eric Denarier, Jacques Mazzega, Jean-Yves Rinckel, Laurence Lafanechère, Bénédicte Elena-Herrmann, Jesse W. Rowley, Karin Sadoul
Blood Adv. 2023 Oct 24; 7(20): 6290–6302. Published online 2023 Aug 30. doi: 10.1182/bloodadvances.2023010423
PMCID:
PMC10589785
AbstractArticlePDF–3.7M
11.
NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition
Tie‐Gang Meng, Jia‐Ni Guo, Liu Zhu, Yike Yin, Feng Wang, Zhi‐Ming Han, Lei Lei, Xue‐Shan Ma, Yue Xue, Wei Yue, Xiao‐Qing Nie, Zheng‐Hui Zhao, Hong‐Yong Zhang, Si‐Min Sun, Ying‐Chun Ouyang, Yi Hou, Heide Schatten, Zhenyu Ju, Xiang‐Hong Ou, Zhen‐Bo Wang, Catherine C. L. Wong, Zhonghan Li, Qing‐Yuan Sun
Adv Sci (Weinh) 2023 Sep; 10(27): 2301940. Published online 2023 Jul 26. doi: 10.1002/advs.202301940
PMCID:
PMC10520637
AbstractArticlePDF–6.6M
12.
Partial skeletal muscle-specific Drp1 knockout enhances insulin sensitivity in diet-induced obese mice, but not in lean mice
Benjamin A. Kugler, Jared Lourie, Nicolas Berger, Nana Lin, Paul Nguyen, Edzana DosSantos, Abir Ali, Amira Sesay, H. Grace Rosen, Baby Kalemba, Gregory M. Hendricks, Joseph A. Houmard, Hiromi Sesaki, Philimon Gona, Tongjian You, Zhen Yan, Kai Zou
Mol Metab. 2023 Nov; 77: 101802. Published online 2023 Sep 9. doi: 10.1016/j.molmet.2023.101802
PMCID:
PMC10511484
AbstractArticlePDF–4.5M
13.
Epigenetic modulation of Drp1-mediated mitochondrial fission by inhibition of S-adenosylhomocysteine hydrolase promotes vascular senescence and atherosclerosis
Yiran You, Xu Chen, Yu Chen, Juan Pang, Qian Chen, Qiannan Liu, Hongliang Xue, Yupeng Zeng, Jinghe Xiao, Jiaxin Mi, Yi Tang, Wenhua Ling
Redox Biol. 2023 Sep; 65: 102828. Published online 2023 Jul 25. doi: 10.1016/j.redox.2023.102828
PMCID:
PMC10400927
AbstractArticlePDF–16M
14.
Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy
Riddhita Mukherjee, Laura H. Tetri, Sin-Jin Li, Giovanni Fajardo, Nicolai P. Ostberg, Kaleb B. Tsegay, Kanika Gera, Timothy T. Cornell, Daniel Bernstein, Daria Mochly-Rosen, Bereketeab Haileselassie
J Mol Cell Cardiol. Author manuscript; available in PMC 2024 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2023 Apr; 177: 28–37. Published online 2023 Feb 24. doi: 10.1016/j.yjmcc.2023.01.008
PMCID:
PMC10358757
AbstractArticlePDF–1.8M
15.
Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction
Luis Rios, Suman Pokhrel, Sin-Jin Li, Gwangbeom Heo, Bereketeab Haileselassie, Daria Mochly-Rosen
Nat Commun. 2023; 14: 4356. Published online 2023 Jul 19. doi: 10.1038/s41467-023-40043-0
PMCID:
PMC10356917
AbstractArticlePDF–2.7M
16.
Distinct Roles of DRP1 in Conventional and Alternative Mitophagy in Obesity Cardiomyopathy
Mingming Tong, Risa Mukai, Satvik Mareedu, Peiyong Zhai, Shin-ichi Oka, Chun-Yang Huang, Chiao-Po Hsu, Fawad A. K. Yousufzai, Luke Fritzky, Wataru Mizushima, Gopal J. Babu, Junichi Sadoshima
Circ Res. Author manuscript; available in PMC 2024 Jun 23.
Published in final edited form as: Circ Res. 2023 Jun 23; 133(1): 6–21. Published online 2023 May 26. doi: 10.1161/CIRCRESAHA.123.322512
PMCID:
PMC10330464
AbstractArticlePDF–3.5M
17.
Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
Dane T. Sessions, Kee-Beom Kim, Jennifer A. Kashatus, Nikolas Churchill, Kwon-Sik Park, Marty W. Mayo, Hiromi Sesaki, David F. Kashatus
Cell Rep. Author manuscript; available in PMC 2023 Jun 14.
Published in final edited form as: Cell Rep. 2022 Dec 13; 41(11): 111818. doi: 10.1016/j.celrep.2022.111818
PMCID:
PMC10265649
AbstractArticlePDF–2.8M
18.
β-arrestin1 regulates astrocytic reactivity via Drp1-dependent mitochondrial fission: implications in postoperative delirium
Fuzhou Hua, Hong Zhu, Wen Yu, Qingcui Zheng, Lieliang Zhang, Weidong Liang, Yue Lin, Fan Xiao, Pengcheng Yi, Yanhong Xiong, Yao Dong, Hua Li, Lanran Fang, Hailin Liu, Jun Ying, Xifeng Wang
J Neuroinflammation. 2023; 20: 113. Published online 2023 May 11. doi: 10.1186/s12974-023-02794-x
PMCID:
PMC10173541
AbstractArticlePDF–17M
19.
CENP-F-dependent DRP1 function regulates APC/C activity during oocyte meiosis I
Cheng-Jie Zhou, Xing-Yue Wang, Yan-Hua Dong, Dong-Hui Wang, Zhe Han, Xiao-Jie Zhang, Qing-Yuan Sun, John Carroll, Cheng-Guang Liang
Nat Commun. 2022; 13: 7732. Published online 2022 Dec 13. doi: 10.1038/s41467-022-35461-5
PMCID:
PMC9747930
AbstractArticlePDF–7.6M
20.
Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation
Xiaowen Ma, Allen Chen, Luma Melo, Ana Clemente-Sanchez, Xiaojuan Chao, Ali Reza Ahmadi, Brandon Peiffer, Zhaoli Sun, Hiromi Sesaki, Tiangang Li, Xiaokun Wang, Wanqing Liu, Ramon Bataller, Hong-Min Ni, Wen-Xing Ding
Hepatology. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Hepatology. 2023 Jan 1; 77(1): 159–175. Published online 2022 Jul 5. doi: 10.1002/hep.32604
PMCID:
PMC9744966
AbstractArticlePDF–4.9M

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