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Combined effects of prostaglandin E receptor subtype EP₁ and subtype EP₄ antagonists on intestinal tumorigenesis in adenomatous polyposis coli gene knockout mice

Tomohiro Kitamura, Masaki Itoh, Tetsuo Noda, Kousuke Tani, Michiyoshi Kobayashi, Takayuki Maruyama, Kaoru Kobayashi, Shuichi Ohuchida, Takashi Sugimura, Keiji Wakabayashi

Cancer Sci. 2003 Jul; 94(7): 618–621. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01492.x

PMCID:: PMC11160211

Abstract Article PDF–112K

Select item 104004692.

EP1 activation inhibits doxorubicin-cardiomyocyte ferroptosis via Nrf2

Bei Wang, Yuxuan Jin, Jiao Liu, Qian Liu, Yujun Shen, Shengkai Zuo, Ying Yu

Redox Biol. 2023 Sep; 65: 102825. Published online 2023 Jul 24. doi: 10.1016/j.redox.2023.102825

PMCID:: PMC10400469

Abstract Article PDF–12M

Select item 82115403.

Fever During Localized Inflammation in Mice Is Elicited by a Humoral Pathway and Depends on Brain Endothelial Interleukin-1 and Interleukin-6 Signaling and Central EP₃ Receptors

Anna Eskilsson, Kiseko Shionoya, David Engblom, Anders Blomqvist

J Neurosci. 2021 Jun 16; 41(24): 5206–5218. doi: 10.1523/JNEUROSCI.0313-21.2021

PMCID:: PMC8211540

Abstract Article PDF–5.4M

Select item 75198874.

Mechanistic definition of the cardiovascular mPGES-1/COX-2/ADMA axis

Nicholas S Kirkby, Joan Raouf, Blerina Ahmetaj-Shala, Bin Liu, Sarah I Mazi, Matthew L Edin, Mark Geoffrey Chambers, Marina Korotkova, Xiaomeng Wang, Walter Wahli, Darryl C Zeldin, Rolf Nüsing, Yingbi Zhou, Per-Johan Jakobsson, Jane A Mitchell

Cardiovasc Res. 2020 Oct 1; 116(12): 1972–1980. Published online 2019 Nov 5. doi: 10.1093/cvr/cvz290

PMCID:: PMC7519887

Abstract Article PDF–928K

Select item 67901625.

Inhibition of the Prostaglandin EP-1 Receptor in Periosteum Progenitor Cells Enhances Osteoblast Differentiation and Fracture Repair

Marina Feigenson, Jennifer H. Jonason, Jie Shen, Alayna E. Loiselle, Hani A. Awad, Regis J. O’Keefe

Ann Biomed Eng. Author manuscript; available in PMC 2020 Oct 12.

Published before final editing as: Ann Biomed Eng. 2019 Apr 12 : 10.1007/s10439-019-02264-7. doi: 10.1007/s10439-019-02264-7 [Epub ahead of print]

PMCID:: PMC6790162

Abstract Article PDF–1.7M

Select item 60564816.

Contribution of prostanoid FP receptor and prostaglandins in transient inflammatory ocular hypertension

Reiko Yamagishi-Kimura, Megumi Honjo, Makoto Aihara

Sci Rep. 2018; 8: 11098. Published online 2018 Jul 23. doi: 10.1038/s41598-018-29273-1

PMCID:: PMC6056481

Abstract Article PDF–1.3M

Select item 57748567.

PGE2 Receptor Subtype 1 (EP1) Regulates Mesenchymal Stromal Cell Osteogenic Differentiation by Modulating Cellular Energy Metabolism

M Feigenson, RA Eliseev, JH Jonason, BN Mills, RJ O’Keefe

J Cell Biochem. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: J Cell Biochem. 2017 Dec; 118(12): 4383–4393. Published online 2017 May 31. doi: 10.1002/jcb.26092

PMCID:: PMC5774856

Abstract Article PDF–2.4M

Select item 57535988.

Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

Lawrence R Shiow, Geraldine Favrais, Lucas Schirmer, Anne-Laure Schang, Sara Cipriani, Christian Andres, Jaclyn N Wright, Hiroko Nobuta, Bobbi Fleiss, Pierre Gressens, David H Rowitch

Glia. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Glia. 2017 Dec; 65(12): 2024–2037. Published online 2017 Aug 30. doi: 10.1002/glia.23212

PMCID:: PMC5753598

Abstract Article PDF–904K

Select item 56685869.

PGE₂ upregulates renin through E-prostanoid receptor 1 via PKC/cAMP/CREB pathway in M-1 cells

Alexis A. Gonzalez, Nicolas Salinas-Parra, Dan Leach, L. Gabriel Navar, Minolfa C. Prieto

Am J Physiol Renal Physiol. 2017 Oct 1; 313(4): F1038–F1049. Published online 2017 Jul 12. doi: 10.1152/ajprenal.00194.2017

PMCID:: PMC5668586

Abstract Article

Select item 503346510.

Obligatory Role of EP1 Receptors in the Increase in Cerebral Blood Flow Produced by Hypercapnia in the Mice

Ken Uekawa, Kenzo Koizumi, Jason Hwang, Nathalie Brunier, Yorito Hattori, Ping Zhou, Laibaik Park

PLoS One. 2016; 11(9): e0163329. Published online 2016 Sep 22. doi: 10.1371/journal.pone.0163329

PMCID:: PMC5033465

Abstract Article PDF–2.2M

Select item 473117011.

Prostaglandin-dependent modulation of dopaminergic neurotransmission elicits inflammation-induced aversion in mice

Michael Fritz, Anna M. Klawonn, Anna Nilsson, Anand Kumar Singh, Joanna Zajdel, Daniel Björk Wilhelms, Michael Lazarus, Andreas Löfberg, Maarit Jaarola, Unn Örtegren Kugelberg, Timothy R. Billiar, David J. Hackam, Chhinder P. Sodhi, Matthew D. Breyer, Johan Jakobsson, Markus Schwaninger, Günther Schütz, Jan Rodriguez Parkitna, Clifford B. Saper, Anders Blomqvist, David Engblom

J Clin Invest. 2016 Feb 1; 126(2): 695–705. Published online 2015 Dec 21. doi: 10.1172/JCI83844

PMCID:: PMC4731170

Abstract Article PDF–1.3M

Select item 469917512.

PGE₂ EP1 Receptor Deletion Attenuates 6-OHDA-Induced Parkinsonism in Mice: Old Switch, New Target

Abdullah Shafique Ahmad, Takayuki Maruyama, Shuh Narumiya, Sylvain Doré

Neurotox Res. Author manuscript; available in PMC 2016 Jan 4.

Published in final edited form as: Neurotox Res. 2013 Apr; 23(3): 260–266. Published online 2013 Feb 6. doi: 10.1007/s12640-013-9381-8

PMCID:: PMC4699175

Abstract Article PDF–646K

Select item 467369313.

Detrimental role of the EP1 prostanoid receptor in blood-brain barrier damage following experimental ischemic stroke

Jan C. Frankowski, Kelly M. DeMars, Abdullah S. Ahmad, Kimberly E. Hawkins, Changjun Yang, Jenna L. Leclerc, Sylvain Doré, Eduardo Candelario-Jalil

Sci Rep. 2015; 5: 17956. Published online 2015 Dec 9. doi: 10.1038/srep17956

PMCID:: PMC4673693

Abstract Article PDF–2.2M

Select item 443753214.

Loss of the PGE2 Receptor EP1 enhances bone acquisition, which protects against age and ovariectomy-induced impairments in bone strength

Minjie Zhang, Marina Feigenson, Tzong-jen Sheu, Hani A. Awad, Edward M. Schwarz, Jennifer H. Jonason, Alayna E. Loiselle, Regis J. O’Keefe

Bone. Author manuscript; available in PMC 2016 Mar 1.

Published in final edited form as: Bone. 2015 Mar; 72: 92–100. Published online 2014 Nov 29. doi: 10.1016/j.bone.2014.11.018

PMCID:: PMC4437532

Abstract Article PDF–1.3M

Select item 441071015.

HIF-1α regulates hypoxia-induced EP1 expression in osteoblastic cells

Damian C. Genetos, Christina M. Lee, Alice Wong, Clare E. Yellowley

J Cell Biochem. Author manuscript; available in PMC 2015 Apr 27.

Published in final edited form as: J Cell Biochem. 2009 May 15; 107(2): 233–239. doi: 10.1002/jcb.22119

PMCID:: PMC4410710

Abstract Article PDF–591K

Select item 424521716.

Role of the Prostaglandin E₂ EP1 Receptor in Traumatic Brain Injury

Alexander V. Glushakov, Jawad A. Fazal, Shuh Narumiya, Sylvain Doré

PLoS One. 2014; 9(11): e113689. Published online 2014 Nov 26. doi: 10.1371/journal.pone.0113689

PMCID:: PMC4245217

Abstract Article PDF–8.9M

Select item 413078717.

The prostaglandin EP1 receptor potentiates kainate receptor activation via a protein kinase C pathway and exacerbates status epilepticus

Asheebo Rojas, Paoula Gueorguieva, Nadia Lelutiu, Yi Quan, Renee Shaw, Raymond Dingledine

Neurobiol Dis. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Neurobiol Dis. 2014 Oct; 70: 74–89. Published online 2014 Jun 19. doi: 10.1016/j.nbd.2014.06.004

PMCID:: PMC4130787

Abstract Article PDF–3.0M

Select item 410843918.

PGE₂ Promotes Apoptosis Induced by Cytokine Deprivation through EP3 Receptor and Induces Bim in Mouse Mast Cells

Martina Kovarova, Beverly H. Koller

PLoS One. 2014; 9(7): e102948. Published online 2014 Jul 23. doi: 10.1371/journal.pone.0102948

PMCID:: PMC4108439

Abstract Article PDF–1.5M

Select item 406530719.

Mast cell maturation is driven via a group III phospholipase A₂-prostaglandin D₂–DP1 receptor paracrine axis

Yoshitaka Taketomi, Noriko Ueno, Takumi Kojima, Hiroyasu Sato, Remi Murase, Kei Yamamoto, Satoshi Tanaka, Mariko Sakanaka, Masanori Nakamura, Yasumasa Nishito, Momoko Kawana, Naotomo Kambe, Kazutaka Ikeda, Ryo Taguchi, Satoshi Nakamizo, Kenji Kabashima, Michael H. Gelb, Makoto Arita, Takehiko Yokomizo, Motonao Nakamura, Kikuko Watanabe, Hiroyuki Hirai, Masataka Nakamura, Yoshimichi Okayama, Chisei Ra, Kosuke Aritake, Yoshihiro Urade, Kazushi Morimoto, Yukihiko Sugimoto, Takao Shimizu, Shuh Narumiya, Shuntaro Hara, Makoto Murakami

Nat Immunol. Author manuscript; available in PMC 2014 Jun 21.

Published in final edited form as: Nat Immunol. 2013 Jun; 14(6): 554–563. Published online 2013 Apr 28. doi: 10.1038/ni.2586

PMCID:: PMC4065307

Abstract Article PDF–1.0M

Select item 384025920.

COX-1-derived PGE₂ and PGE₂ type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca²⁺ influx in the subfornical organ

Gang Wang, Pallabi Sarkar, Jeffrey R. Peterson, Josef Anrather, Joseph P. Pierce, Jamie M. Moore, Ji Feng, Ping Zhou, Teresa A. Milner, Virginia M. Pickel, Costantino Iadecola, Robin L. Davisson

Am J Physiol Heart Circ Physiol. 2013 Nov 15; 305(10): H1451–H1461. Published online 2013 Sep 6. doi: 10.1152/ajpheart.00238.2013

PMCID:: PMC3840259

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