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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 104642432.

Knockdown of TMEM30A in renal tubular epithelial cells leads to reduced glucose absorption

Sipei Chen, Xinrou Song, Qiong Xiao, Li Wang, Xianjun Zhu, Yang Zou, Guisen Li

BMC Nephrol. 2023; 24: 250. Published online 2023 Aug 23. doi: 10.1186/s12882-023-03299-8

PMCID:: PMC10464243

Abstract Article PDF–7.1M

Select item 100351923.

TMEM30A is essential for hair cell polarity maintenance in postnatal mouse cochlea

Yazhi Xing, Kun Peng, Qian Yi, Dongzhen Yu, Haibo Shi, Guang Yang, Shankai Yin

Cell Mol Biol Lett. 2023; 28: 23. Published online 2023 Mar 23. doi: 10.1186/s11658-023-00437-w

PMCID:: PMC10035192

Abstract Article PDF–7.8M

Select item 85616304.

Phospholipid‐flippase chaperone CDC50A is required for synapse maintenance by regulating phosphatidylserine exposure

Tao Li, Diankun Yu, Hayeon C Oak, Beika Zhu, Li Wang, Xueqiao Jiang, Robert S Molday, Arnold Kriegstein, Xianhua Piao

EMBO J. 2021 Nov 2; 40(21): e107915. Published online 2021 Sep 29. doi: 10.15252/embj.2021107915

PMCID:: PMC8561630

Abstract Article PDF–7.5M

Select item 84174325.

The phosphatidylserine flippase β-subunit Tmem30a is essential for normal insulin maturation and secretion

Yeming Yang, Kuanxiang Sun, Wenjing Liu, Xiao Li, Wanli Tian, Ping Shuai, Xianjun Zhu

Mol Ther. 2021 Sep 1; 29(9): 2854–2872. Published online 2021 Apr 23. doi: 10.1016/j.ymthe.2021.04.026

PMCID:: PMC8417432

Abstract Article PDF–4.7M

Select item 83279586.

Microglial MERTK eliminates phosphatidylserine‐displaying inhibitory post‐synapses

Jungjoo Park, Yeeun Choi, Eunji Jung, Seung‐Hee Lee, Jong‐Woo Sohn, Won‐Suk Chung

EMBO J. 2021 Aug 2; 40(15): e107121. Published online 2021 May 19. doi: 10.15252/embj.2020107121

PMCID:: PMC8327958

Abstract Article PDF–6.5M

Select item 82462687.

Loss of phosphatidylserine flippase β-subunit Tmem30a in podocytes leads to albuminuria and glomerulosclerosis

Wenjing Liu, Lei Peng, Wanli Tian, Yi Li, Ping Zhang, Kuanxiang Sun, Yeming Yang, Xiao Li, Guisen Li, Xianjun Zhu

Dis Model Mech. 2021 Jun 1; 14(6): dmm048777. Published online 2021 Jun 25. doi: 10.1242/dmm.048777

PMCID:: PMC8246268

Abstract Article

Select item 72270288.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 68864249.

Deletion of a flippase subunit Tmem30a in hematopoietic cells impairs mouse fetal liver erythropoiesis

Fan Yang, Yumin Huang, Xianda Chen, Lu Liu, Dandan Liao, Huan Zhang, Gang Huang, Wenjing Liu, Xianjun Zhu, Wengong Wang, Cheryl A. Lobo, Karina Yazdanbakhsh, Xiuli An, Zhenyu Ju

Haematologica. 2019 Oct; 104(10): 1984–1994. Prepublished online 2019 Feb 28. doi: 10.3324/haematol.2018.203992

PMCID:: PMC6886424

Abstract Article PDF–5.8M

Select item 645951010.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Abstract Article PDF–5.1M

Select item 612528911.

Disruption of Tmem30a results in cerebellar ataxia and degeneration of Purkinje cells

Yeming Yang, Kuanxiang Sun, Wenjing Liu, Lin Zhang, Kun Peng, Shanshan Zhang, Shujin Li, Mu Yang, Zhilin Jiang, Fang Lu, Xianjun Zhu

Cell Death Dis. 2018 Sep; 9(9): 899. Published online 2018 Sep 5. doi: 10.1038/s41419-018-0938-6

PMCID:: PMC6125289

Abstract Article PDF–6.0M

Select item 608075512.

TMEM30A is a candidate interacting partner for the β-carboxyl-terminal fragment of amyloid-β precursor protein in endosomes

Nobumasa Takasugi, Runa Araya, Yuji Kamikubo, Nanaka Kaneshiro, Ryosuke Imaoka, Hao Jin, Taku Kashiyama, Yoshie Hashimoto, Masaru Kurosawa, Takashi Uehara, Nobuyuki Nukina, Takashi Sakurai

PLoS One. 2018; 13(8): e0200988. Published online 2018 Aug 7. doi: 10.1371/journal.pone.0200988

PMCID:: PMC6080755

Abstract Article PDF–1.9M

Select item 557122313.

Loss of Tmem30a leads to photoreceptor degeneration

Lin Zhang, Yeming Yang, Shujin Li, Shanshan Zhang, Xiong Zhu, Zhengfu Tai, Mu Yang, Yuqing Liu, Xinzheng Guo, Bo Chen, Zhilin Jiang, Fang Lu, Xianjun Zhu

Sci Rep. 2017; 7: 9296. Published online 2017 Aug 24. doi: 10.1038/s41598-017-09506-5

PMCID:: PMC5571223

Abstract Article PDF–7.1M

Select item 435840314.

Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt

Jernej Murn, Kathi Zarnack, Yawei J. Yang, Omer Durak, Elisabeth A. Murphy, Sihem Cheloufi, Dilenny M. Gonzalez, Marianna Teplova, Tomaž Curk, Johannes Zuber, Dinshaw J. Patel, Jernej Ule, Nicholas M. Luscombe, Li-Huei Tsai, Christopher A. Walsh, Yang Shi

Genes Dev. 2015 Mar 1; 29(5): 501–512. doi: 10.1101/gad.258483.115

PMCID:: PMC4358403

Abstract Article PDF–1.4M

Select item 357609615.

Role for Phospholipid Flippase Complex of ATP8A1 and CDC50A Proteins in Cell Migration

Utako Kato, Hironori Inadome, Masatoshi Yamamoto, Kazuo Emoto, Toshihide Kobayashi, Masato Umeda

J Biol Chem. 2013 Feb 15; 288(7): 4922–4934. Published online 2012 Dec 26. doi: 10.1074/jbc.M112.402701

PMCID:: PMC3576096

Abstract Article PDF–4.2M

Select item 357241016.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Abstract Article PDF–1.1M

Select item 335112517.

Cellular Localization and Biochemical Analysis of Mammalian CDC50A, a Glycosylated β-subunit for P4 ATPases

Dineke E. Folmer, Kam S. Mok, Sebastiaan W. de Wee, Suzanne Duijst, Johan K. Hiralall, Jurgen Seppen, Ronald P. J. Oude Elferink, Coen C. Paulusma

J Histochem Cytochem. 2012 Mar; 60(3): 205–218. doi: 10.1369/0022155411435705

PMCID:: PMC3351125

Abstract Article PDF–5.4M

Select item 317805918.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 302253419.

A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo

Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio

PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582

PMCID:: PMC3022534

Abstract Article PDF–3.8M

Select item 52892820.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

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