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Items: 1 to 20 of 108

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Fibroblast growth factor receptor-4 mediates activation of Nuclear Factor Erythroid 2-Related Factor-2 in gastric tumorigenesis
Mohammed Soutto, Xing Zhang, Nadeem Bhat, Zheng Chen, Shoumin Zhu, Selma Maacha, Melanie Genoula, Omar El-Gazzaz, Dunfa Peng, Heng Lu, Oliver G. McDonald, Xi Steven Chen, Longlong Cao, Zekuan Xu, Wael El-Rifai
Redox Biol. 2024 Feb; 69: 102998. Published online 2023 Dec 19. doi: 10.1016/j.redox.2023.102998
PMCID:
PMC10787301
AbstractArticlePDF–17M
3.
Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth
Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima
Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916
PMCID:
PMC10403640
AbstractArticlePDF–2.1M
4.
Up-Regulation of Astrocytic Fgfr4 Expression in Adult Mice after Spinal Cord Injury
Claire Mathilde Bringuier, Harun Najib Noristani, Jean-Christophe Perez, Maida Cardoso, Christophe Goze-Bac, Yannick Nicolas Gerber, Florence Evelyne Perrin
Cells. 2023 Feb; 12(4): 528. Published online 2023 Feb 6. doi: 10.3390/cells12040528
PMCID:
PMC9954417
AbstractArticlePDF–20M
5.
Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis
Francois Moreau, Bruna Brasil Brunao, Xiang-Yu Liu, Frederic Tremblay, Kevin Fitzgerald, Julian Avila-Pacheco, Clary Clish, Ronald C. Kahn, Samir Softic
J Lipid Res. 2023 Feb; 64(2): 100324. Published online 2022 Dec 29. doi: 10.1016/j.jlr.2022.100324
PMCID:
PMC9871743
AbstractArticlePDF–2.9M
6.
TGF-β signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development
Jifan Feng, Xia Han, Yuan Yuan, Courtney Kyeong Cho, Eva Janečková, Tingwei Guo, Siddhika Pareek, Md Shaifur Rahman, Banghong Zheng, Jing Bi, Junjun Jing, Mingyi Zhang, Jian Xu, Thach-Vu Ho, Yang Chai
eLife. 2022; 11: e80405. Published online 2022 Dec 21. doi: 10.7554/eLife.80405
PMCID:
PMC9771365
AbstractArticlePDF–17M
7.
FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes
Christopher Yanucil, Dominik Kentrup, Xueyi Li, Alexander Grabner, Karla Schramm, Eliana C. Martinez, Jinliang Li, Isaac Campos, Brian Czaya, Kylie Heitman, David Westbrook, Adam R. Wende, Alexis Sloan, Johanna M. Roche, Alessia Fornoni, Michael S. Kapiloff, Christian Faul
Sci Rep. 2022; 12: 7326. Published online 2022 May 5. doi: 10.1038/s41598-022-11033-x
PMCID:
PMC9072546
AbstractArticlePDF–6.4M
8.
Hyperphosphatemia increases inflammation to exacerbate anemia and skeletal muscle wasting independently of FGF23-FGFR4 signaling
Brian Czaya, Kylie Heitman, Isaac Campos, Christopher Yanucil, Dominik Kentrup, David Westbrook, Orlando Gutierrez, Jodie L Babitt, Grace Jung, Isidro B Salusky, Mark Hanudel, Christian Faul
eLife. 2022; 11: e74782. Published online 2022 Mar 18. doi: 10.7554/eLife.74782
PMCID:
PMC8963881
AbstractArticlePDF–15M
9.
Fibroblast growth factor 23 (FGF23) induces ventricular arrhythmias and prolongs QTc interval in mice in an FGF receptor 4-dependent manner
Jonah M. Graves, Julian A. Vallejo, Chelsea S. Hamill, Derek Wang, Rohan Ahuja, Shaan Patel, Christian Faul, Michael J. Wacker
Am J Physiol Heart Circ Physiol. 2021 Jun 1; 320(6): H2283–H2294. Published online 2021 Apr 30. doi: 10.1152/ajpheart.00798.2020
PMCID:
PMC8424547
AbstractArticle
10.
Aberrant FGFR4 signaling worsens nonalcoholic steatohepatitis in FGF21KO mice
Youxi Yu, Xiaoju Shi, Qianqian Zheng, Xingtong Wang, Xingkai Liu, Min Tan, Guoyue Lv, Ping Zhang, Robert C. Martin, Yan Li
Int J Biol Sci. 2021; 17(10): 2576–2589. Published online 2021 Jun 22. doi: 10.7150/ijbs.58776
PMCID:
PMC8315028
AbstractArticlePDF–3.3M
11.
Homeobox B5 promotes metastasis and poor prognosis in Hepatocellular Carcinoma, via FGFR4 and CXCL1 upregulation
Qin He, Wenjie Huang, Danfei Liu, Tongyue Zhang, Yijun Wang, Xiaoyu Ji, Meng Xie, Mengyu Sun, Dean Tian, Mei Liu, Limin Xia
Theranostics. 2021; 11(12): 5759–5777. Published online 2021 Mar 31. doi: 10.7150/thno.57659
PMCID:
PMC8058721
AbstractArticlePDF–4.9M
12.
FGF23 induced left ventricular hypertrophy mediated by FGFR4 signaling in the myocardium is attenuated by soluble Klotho in mice
Xiaobin Han, Chun Cai, Zhousheng Xiao, L. Darryl Quarles
J Mol Cell Cardiol. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: J Mol Cell Cardiol. 2020 Jan; 138: 66–74. Published online 2019 Nov 21. doi: 10.1016/j.yjmcc.2019.11.149
PMCID:
PMC7195870
AbstractArticlePDF–1.4M
13.
Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development
Megha Agarwal, Akashi Sharma, Pankaj Kumar, Amit Kumar, Anushree Bharadwaj, Masum Saini, Gabrielle Kardon, Sam J. Mathew
Development. 2020 Apr 1; 147(7): dev184507. Published online 2020 Apr 6. doi: 10.1242/dev.184507
PMCID:
PMC7157585
AbstractArticle
14.
Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development
Eva Janečková, Jifan Feng, Jingyuan Li, Gabriela Rodriguez, Yang Chai
PLoS One. 2019; 14(10): e0223879. Published online 2019 Oct 15. doi: 10.1371/journal.pone.0223879
PMCID:
PMC6793855
AbstractArticlePDF–5.2M
15.
FGFR4 does not contribute to progression of chronic kidney disease
Ashlee Taylor, Christopher Yanucil, John Musgrove, Melody Shi, Shintaro Ide, Tomokazu Souma, Christian Faul, Myles Wolf, Alexander Grabner
Sci Rep. 2019; 9: 14023. Published online 2019 Oct 1. doi: 10.1038/s41598-019-50669-0
PMCID:
PMC6773883
AbstractArticlePDF–5.9M
16.
Laminar Patterning in the Developing Neocortex by Temporally Coordinated Fibroblast Growth Factor Signaling
Hiroshi Hasegawa, Shizuko Ashigaki, Masako Takamatsu, Rika Suzuki-Migishima, Norihiko Ohbayashi, Nobuyuki Itoh, Shinji Takada, Yasuto Tanabe
J Neurosci. 2004 Oct 6; 24(40): 8711–8719. doi: 10.1523/JNEUROSCI.3070-04.2004
PMCID:
PMC6729962
AbstractArticlePDF–535K
17.
A Local Source of FGF Initiates Development of the Unmyelinated Lineage of Sensory Neurons
Saïda Hadjab, Marina C. M. Franck, Yiqiao Wang, Ulrich Sterzenbach, Anil Sharma, Patrik Ernfors, Francois Lallemend
J Neurosci. 2013 Nov 6; 33(45): 17656–17666. doi: 10.1523/JNEUROSCI.1090-13.2013
PMCID:
PMC6618424
AbstractArticlePDF–4.3M
18.
Peptides containing the RERMS sequence of amyloid beta/A4 protein precursor bind cell surface and promote neurite extension
LW Jin, H Ninomiya, JM Roch, D Schubert, E Masliah, DA Otero, T Saitoh
J Neurosci. 1994 Sep 1; 14(9): 5461–5470. doi: 10.1523/JNEUROSCI.14-09-05461.1994
PMCID:
PMC6577069
AbstractPDF–2.2M
19.
Synergistic effects of TGFβ2, WNT9a, and FGFR4 signals attenuate satellite cell differentiation during skeletal muscle development
Weiya Zhang, Yueyuan Xu, Lu Zhang, Sheng Wang, Binxu Yin, Shuhong Zhao, Xinyun Li
Aging Cell. 2018 Aug; 17(4): e12788. Published online 2018 Jun 4. doi: 10.1111/acel.12788
PMCID:
PMC6052404
AbstractArticlePDF–6.6M
20.
Established gastric cancer cell lines transplantable into C57BL/6 mice show fibroblast growth factor receptor 4 promotion of tumor growth
Masami Yamamoto, Sachiyo Nomura, Akihiro Hosoi, Koji Nagaoka, Tamaki Iino, Tomohiko Yasuda, Tomoko Saito, Hirokazu Matsushita, Eiji Uchida, Yasuyuki Seto, James R. Goldenring, Kazuhiko Kakimi, Masae Tatematsu, Tetsuya Tsukamoto
Cancer Sci. 2018 May; 109(5): 1480–1492. Published online 2018 Apr 15. doi: 10.1111/cas.13569
PMCID:
PMC5980194
AbstractArticlePDF–12M

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