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Items: 1 to 20 of 92

1.
The Role of Ubiquitination and the E3 Ligase Nedd4 in Regulating Corneal Epithelial Wound Healing
Xuemei Ling, Weiwei Xu, Jingjing Tang, Qiongjie Cao, Guangying Luo, Xiaoyan Chen, Shuai Yang, Peter Sol Reinach, Dongsheng Yan
Invest Ophthalmol Vis Sci. 2024 Jun; 65(6): 29. Published online 2024 Jun 18. doi: 10.1167/iovs.65.6.29
PMCID:
PMC11186577
AbstractArticlePDF–9.4M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The E3 ubiquitin ligase NEDD4-1 protects against acetaminophen-induced liver injury by targeting VDAC1 for degradation
Yiwei Zhu, Lin Lei, Xinghui Wang, Linfang Chen, Wei Li, Jinxia Li, Chenchen Zhao, Xiliang Du, Yuxiang Song, Wenwen Gao, Guowen Liu, Xinwei Li
Acta Pharm Sin B. 2023 Apr; 13(4): 1616–1630. Published online 2023 Jan 29. doi: 10.1016/j.apsb.2023.01.019
PMCID:
PMC10150139
AbstractArticlePDF–5.5M
4.
MicroRNA‐155‐5p in serum derived‐exosomes promotes ischaemia–reperfusion injury by reducing CypD ubiquitination by NEDD4
Chenkai Hu, Junyu Liao, Ruiyan Huang, Qiang Su, Lei He
ESC Heart Fail. 2023 Apr; 10(2): 1144–1157. Published online 2023 Jan 11. doi: 10.1002/ehf2.14279
PMCID:
PMC10053265
AbstractArticlePDF–2.3M
5.
Phosphorylation by IKKβ Promotes the Degradation of HMGCL via NEDD4 in Lung Cancer
Chenxi Zhong, Guosheng Xiong, Haitang Yang, Xiaohua Du, Jiankui Du, Feng Yao, Wentao Fang, Yuezhen Deng
Int J Biol Sci. 2023; 19(4): 1110–1122. Published online 2023 Feb 5. doi: 10.7150/ijbs.82015
PMCID:
PMC10008690
AbstractArticlePDF–6.9M
6.
Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke
Zexuan Hong, Jun Cao, Dandan Liu, Maozhu Liu, Mengyuan Chen, Fanning Zeng, Zaisheng Qin, Jigang Wang, Tao Tao
J Pharm Anal. 2023 Feb; 13(2): 156–169. Published online 2023 Jan 7. doi: 10.1016/j.jpha.2022.12.002
PMCID:
PMC9999302
AbstractArticlePDF–5.5M
7.
NEDD4 ameliorates myocardial reperfusion injury by preventing macrophages pyroptosis
Wenjing Sun, Hongquan Lu, Shihua Cui, Shenghui Zhao, Haijia Yu, Huihui song, Qiuyue Ruan, Yabin Zhang, Yingjie Chu, Shujuan Dong
Cell Commun Signal. 2023; 21: 29. Published online 2023 Feb 2. doi: 10.1186/s12964-022-01022-y
PMCID:
PMC9896697
AbstractArticlePDF–11M
8.
The AAA‐ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle
Dina Aweida, Shenhav Cohen
EMBO Rep. 2022 Dec; 23(12): e55175. Published online 2022 Oct 24. doi: 10.15252/embr.202255175
PMCID:
PMC9724657
AbstractArticlePDF–3.0M
9.
A Nedd4 E3 Ubiquitin Ligase Pathway Inhibits Robo1 Repulsion and Promotes Commissural Axon Guidance across the Midline
Madhavi Gorla, Karina Chaudhari, Maya Hale, Chloe Potter, Greg J. Bashaw
J Neurosci. 2022 Oct 5; 42(40): 7547–7561. doi: 10.1523/JNEUROSCI.2491-21.2022
PMCID:
PMC9546450
AbstractArticlePDF–4.5M
10.
TRIM27 cooperates with STK38L to inhibit ULK1‐mediated autophagy and promote tumorigenesis
Yi Yang, Yifu Zhu, Shuai Zhou, Peipei Tang, Ran Xu, Yuwei Zhang, Dongping Wei, Jian Wen, Rick F Thorne, Xu Dong Zhang, Jun‐Lin Guan, Lianxin Liu, Mian Wu, Song Chen
EMBO J. 2022 Jul; 41(14): e109777. Published online 2022 Jun 7. doi: 10.15252/embj.2021109777
PMCID:
PMC9289709
AbstractArticlePDF–2.3M
11.
p21-activated kinase 4 controls the aggregation of α-synuclein by reducing the monomeric and aggregated forms of α-synuclein: involvement of the E3 ubiquitin ligase NEDD4-1
So-Yoon Won, Jung-Jin Park, Soon-Tae You, Jong-A Hyeun, Hyong-Kyu Kim, Byung Kwan Jin, Catriona McLean, Eun-Young Shin, Eung-Gook Kim
Cell Death Dis. 2022 Jun; 13(6): 575. Published online 2022 Jun 30. doi: 10.1038/s41419-022-05030-1
PMCID:
PMC9247077
AbstractArticlePDF–4.6M
12.
Loss of NEDD4 causes complete XY gonadal sex reversal in mice
Simon P. Windley, Chloé Mayère, Alice E. McGovern, Natasha L. Harvey, Serge Nef, Quenten Schwarz, Sharad Kumar, Dagmar Wilhelm
Cell Death Dis. 2022 Jan; 13(1): 75. Published online 2022 Jan 24. doi: 10.1038/s41419-022-04519-z
PMCID:
PMC8786929
AbstractArticlePDF–16M
13.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
14.
Beraprost ameliorates postmenopausal osteoporosis by regulating Nedd4-induced Runx2 ubiquitination
Huo-Liang Zheng, Wen-Ning Xu, Wen-Sheng Zhou, Run-Ze Yang, Peng-Bo Chen, Tao Liu, Lei-Sheng Jiang, Sheng-Dan Jiang
Cell Death Dis. 2021 May; 12(5): 497. Published online 2021 May 15. doi: 10.1038/s41419-021-03784-8
PMCID:
PMC8124066
AbstractArticlePDF–4.3M
15.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
16.
The Daam2–VHL–Nedd4 axis governs developmental and regenerative oligodendrocyte differentiation
Xiaoyun Ding, Juyeon Jo, Chih-Yen Wang, Carlo D. Cristobal, Zhongyuan Zuo, Qi Ye, Marvin Wirianto, Aaron Lindeke-Myers, Jong Min Choi, Carrie A. Mohila, Hiroshi Kawabe, Sung Yun Jung, Hugo J. Bellen, Seung-Hee Yoo, Hyun Kyoung Lee
Genes Dev. 2020 Sep 1; 34(17-18): 1177–1189. doi: 10.1101/gad.338046.120
PMCID:
PMC7462057
AbstractArticlePDF–49M
17.
Dietary sodium modulates nephropathy in Nedd4-2-deficient mice
Jantina A. Manning, Sonia S. Shah, Tanya L. Henshall, Andrej Nikolic, John Finnie, Sharad Kumar
Cell Death Differ. 2020 Jun; 27(6): 1832–1843. Published online 2019 Dec 4. doi: 10.1038/s41418-019-0468-5
PMCID:
PMC7244563
AbstractArticlePDF–3.9M
18.
E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation
Qingjun Liu, Shihui Zhang, Zhongjie Sun, Xiao Guo, Hong Zhou
Cell Death Differ. 2019 Nov; 26(11): 2386–2399. Published online 2019 Feb 28. doi: 10.1038/s41418-019-0308-7
PMCID:
PMC6888843
AbstractArticlePDF–2.8M
19.
Reevaluation of the Role of Extracellular Signal-Regulated Kinase 3 in Perinatal Survival and Postnatal Growth Using New Genetically Engineered Mouse Models
Mathilde Soulez, Marc K. Saba-El-Leil, Benjamin Turgeon, Simon Mathien, Philippe Coulombe, Sonia Klinger, Justine Rousseau, Kim Lévesque, Sylvain Meloche
Mol Cell Biol. 2019 Mar 15; 39(6): e00527-18. Prepublished online 2019 Jan 14. Published online 2019 Mar 1. doi: 10.1128/MCB.00527-18
PMCID:
PMC6399666
AbstractArticlePDF–1.1M
20.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M

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