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Items: 1 to 20 of 33

1.
Nuclear receptor 4A1 (NR4A1) silencing protects hepatocyte against hypoxia-reperfusion injury in vitro by activating liver kinase B1 (LKB1)/AMP-activated protein kinase (AMPK) signaling
Yu Zheng, Yingying Tao, Xiaobo Zhan, Qi Wu
Bioengineered. 2022; 13(4): 8349–8359. Published online 2022 Mar 21. doi: 10.1080/21655979.2022.2053804
PMCID:
PMC9161842
AbstractArticlePDF–1.9M
2.
Interaction of Nuclear Receptor Subfamily 4 Group A Member 1 (Nr4a1) and Liver Linase B1 (LKB1) Mitigates Type 2 Diabetes Mellitus by Activating Monophosphate-Activated Protein Kinase (AMPK)/Sirtuin 1 (SIRT1) Axis and Inhibiting Nuclear Factor-kappa B (NF-κB) Activation
Yi Ming, Youmin Yin, Zhaoli Sun
Med Sci Monit. 2020; 26: e920278-1–e920278-9. Published online 2020 Jan 15. doi: 10.12659/MSM.920278
PMCID:
PMC6982402
AbstractArticlePDF–901K
3.
Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway
Juan Ji, Teng‐Fei Xue, Xu‐Dong Guo, Jin Yang, Ruo‐Bing Guo, Juan Wang, Ji‐Ye Huang, Xiao‐Jie Zhao, Xiu‐Lan Sun
Aging Cell. 2018 Aug; 17(4): e12774. Published online 2018 May 8. doi: 10.1111/acel.12774
PMCID:
PMC6052482
AbstractArticlePDF–6.3M
4.
Mutational Analysis of STK11 h Gene in Ovarian Carcinomas
Yoshihiro Nishioka, Kanji Kobayashi, Satoru Sagae, Masaki Sugimura, Shinichi Ishioka, Masami Nagata, Katuhiko Terasawa, Takashi Tokino, Ryuichi Kudo
Jpn J Cancer Res. 1999 Jun; 90(6): 629–632. doi: 10.1111/j.1349-7006.1999.tb00793.x
PMCID:
PMC5926111
SummaryPDF–224K
5.
Lkb1 controls brown adipose tissue growth and thermogenesis by regulating the intracellular localization of CRTC3
Tizhong Shan, Yan Xiong, Pengpeng Zhang, Zhiguo Li, Qingyang Jiang, Pengpeng Bi, Feng Yue, Gongshe Yang, Yizhen Wang, Xiaoqi Liu, Shihuan Kuang
Nat Commun. 2016; 7: 12205. Published online 2016 Jul 27. doi: 10.1038/ncomms12205
PMCID:
PMC4974456
AbstractArticlePDF–1.8M
6.
Liver Kinase B 1 Complex Acts as a Novel Modifier of Myofilament Function and Localizes to the Z-Disk in Cardiac Myocytes
Samantha M. Behunin, Marissa A. Lopez-Pier, Rachel M. Mayfield, Christiane A. Danilo, Yulia Lipovka, Camille Birch, Sarah Lehman, Jil C. Tardiff, Carol C. Gregorio, John P. Konhilas
Arch Biochem Biophys. Author manuscript; available in PMC 2017 Jul 1.
Published in final edited form as: Arch Biochem Biophys. 2016 Jul 1; 601: 32–41. Published online 2016 Mar 10. doi: 10.1016/j.abb.2016.03.012
PMCID:
PMC4899161
AbstractArticlePDF–1.2M
7.
Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats
Shu-Jun Jiang, Hui Dong, Jing-Bin Li, Li-Jun Xu, Xin Zou, Kai-Fu Wang, Fu-Er Lu, Ping Yi
World J Gastroenterol. 2015 Jul 7; 21(25): 7777–7785. Published online 2015 Jul 7. doi: 10.3748/wjg.v21.i25.7777
PMCID:
PMC4491964
AbstractArticlePDF–1.8M
8.
Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4
Bing Luan, Mark O. Goodarzi, Naomi G. Phillips, Xiuqing Guo, Yii-Der I. Chen, Jie Yao, Matthew Allison, Jerome I. Rotter, Reuben Shaw, Marc Montminy
Cell Metab. Author manuscript; available in PMC 2015 Jun 3.
Published in final edited form as: Cell Metab. 2014 Jun 3; 19(6): 1058–1065. Published online 2014 Apr 24. doi: 10.1016/j.cmet.2014.03.024
PMCID:
PMC4207085
AbstractArticlePDF–1.4M
9.
A Mouse Model Uncovers LKB1 as an UVB-Induced DNA Damage Sensor Mediating CDKN1A (p21WAF1/CIP1) Degradation
Rosaura Esteve-Puig, Rosa Gil, Elena González-Sánchez, Joan Josep Bech-Serra, Judit Grueso, Javier Hernández-Losa, Teresa Moliné, Francesc Canals, Berta Ferrer, Javier Cortés, Boris Bastian, Santiago Ramón y Cajal, Juan Martín-Caballero, Juana Maria Flores, Ana Vivancos, Vicenç García-Patos, Juan Ángel Recio
PLoS Genet. 2014 Oct; 10(10): e1004721. Published online 2014 Oct 16. doi: 10.1371/journal.pgen.1004721
PMCID:
PMC4199501
AbstractArticlePDF–2.5M
10.
LKB1/AMPK and PKA Control ABCB11 Trafficking and Polarization in Hepatocytes
László Homolya, Dong Fu, Prabuddha Sengupta, Michal Jarnik, Jean-Pierre Gillet, Lynn Vitale-Cross, J. Silvio Gutkind, Jennifer Lippincott-Schwartz, Irwin M. Arias
PLoS One. 2014; 9(3): e91921. Published online 2014 Mar 18. doi: 10.1371/journal.pone.0091921
PMCID:
PMC3958433
AbstractArticlePDF–2.4M
11.
Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity
Vanessa P. Houde, Maria Stella Ritorto, Robert Gourlay, Joby Varghese, Paul Davies, Natalia Shpiro, Kei Sakamoto, Dario R. Alessi
Biochem J. 2014 Feb 15; 458(Pt 1): 41–56. Prepublished online 2013 Dec 3. Published online 2014 Jan 20. doi: 10.1042/BJ20131324
PMCID:
PMC3898322
AbstractArticlePDF–2.3M
12.
Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons
Wei Huang, Liang She, Xing-ya Chang, Rong-rong Yang, Liang Wang, Hong-bin Ji, Jian-wei Jiao, Mu-ming Poo
Proc Natl Acad Sci U S A. 2014 Jan 7; 111(1): 469–474. Published online 2013 Dec 23. doi: 10.1073/pnas.1321454111
PMCID:
PMC3890881
AbstractArticlePDF–1.5M
13.
Reactive nitrogen species regulate autophagy through ATM-AMPK-TSC2–mediated suppression of mTORC1
Durga N. Tripathi, Rajdeep Chowdhury, Laura J. Trudel, Andrew R. Tee, Rebecca S. Slack, Cheryl Lyn Walker, Gerald N. Wogan
Proc Natl Acad Sci U S A. 2013 Aug 6; 110(32): E2950–E2957. Published online 2013 Jul 22. doi: 10.1073/pnas.1307736110
PMCID:
PMC3740898
AbstractArticlePDF–1.1M
14.
Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation
Elton Zeqiraj, Beatrice Maria Filippi, Maria Deak, Dario R. Alessi, Daan M. F. van Aalten
Science. Author manuscript; available in PMC 2012 Dec 10.
Published in final edited form as: Science. 2009 Dec 18; 326(5960): 1707–1711. Published online 2009 Nov 5. doi: 10.1126/science.1178377
PMCID:
PMC3518268
AbstractArticlePDF–2.3M
15.
Resveratrol Inhibits Cardiac Hypertrophy via AMP-activated Protein Kinase and Akt
Anita Y. M. Chan, Vernon W. Dolinsky, Carrie-Lynn M. Soltys, Benoit Viollet, Shairaz Baksh, Peter E. Light, Jason R. B. Dyck
J Biol Chem. 2008 Aug 29; 283(35): 24194–24201. doi: 10.1074/jbc.M802869200
PMCID:
PMC3259789
AbstractArticlePDF–578K
16.
Sirtuin 1–Mediated Cellular Metabolic Memory of High Glucose Via the LKB1/AMPK/ROS Pathway and Therapeutic Effects of Metformin
Zhi Zheng, Haibing Chen, Jun Li, Tao Li, Bingqing Zheng, Ying Zheng, Huiyi Jin, Ying He, Qing Gu, Xun Xu
Diabetes. 2012 Jan; 61(1): 217–228. Published online 2011 Dec 12. doi: 10.2337/db11-0416
PMCID:
PMC3237662
AbstractArticlePDF–2.1M
17.
Curcumin Differentially Regulates Endoplasmic Reticulum Stress through Transcriptional Corepressor SMILE (Small Heterodimer Partner-interacting Leucine Zipper Protein)-mediated Inhibition of CREBH (cAMP Responsive Element-binding Protein H)
Jagannath Misra, Dipanjan Chanda, Don-kyu Kim, Tiangang Li, Seung-Hoi Koo, Sung-Hoon Back, John Y. L. Chiang, Hueng-Sik Choi
J Biol Chem. 2011 Dec 9; 286(49): 41972–41984. Published online 2011 Oct 12. doi: 10.1074/jbc.M111.274514
PMCID:
PMC3234973
AbstractArticlePDF–2.3M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
Yonghao Cao, Hai Li, Haifeng Liu, Min Zhang, Zichun Hua, Hongbin Ji, Xiaolong Liu
EMBO J. 2011 May 18; 30(10): 2083–2093. Published online 2011 Apr 12. doi: 10.1038/emboj.2011.116
PMCID:
PMC3098487
AbstractArticlePDF–1.8M
20.
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
Reuben J. Shaw, Katja A. Lamia, Debbie Vasquez, Seung-Hoi Koo, Nabeel Bardeesy, Ronald A. DePinho, Marc Montminy, Lewis C. Cantley
Science. Author manuscript; available in PMC 2011 Apr 12.
Published in final edited form as: Science. 2005 Dec 9; 310(5754): 1642–1646. Published online 2005 Nov 24. doi: 10.1126/science.1120781
PMCID:
PMC3074427
AbstractArticlePDF–734K

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