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Select item 113919671.

Anti-aging and immunomodulatory role of caffeine in Drosophila larvae

Firzan Nainu, Sartini Sartini, Muhammad A. Bahar, Asbah Asbah, Reski A. Rosa, Mukarram Mudjahid, Muhammad F. As’ad, Nadila P. Latada

Narra J. 2024 Aug; 4(2): e818. Published online 2024 Jun 28. doi: 10.52225/narra.v4i2.818

PMCID:: PMC11391967

Abstract Article PDF–368K

Select item 113910102.

Vitamin B12 ameliorates gut epithelial injury via modulating the HIF-1 pathway and gut microbiota

Chenxi Feng, Jinhua Yan, Ting Luo, Hong Zhang, Hu Zhang, Yu Yuan, Yi Chen, Haiyang Chen

Cell Mol Life Sci. 2024 Dec; 81(1): 397. Published online 2024 Sep 11. doi: 10.1007/s00018-024-05435-5

PMCID:: PMC11391010

Abstract Article PDF–12M

Select item 113893693.

Protein-coding circular RNA enhances antiviral immunity via JAK/STAT pathway in Drosophila

Dongyang Guo, Wen Xu, Ting Cui, Qiqi Rong, Qingfa Wu

mBio. 2024 Sep; 15(9): e01469-24. Published online 2024 Aug 19. doi: 10.1128/mbio.01469-24

PMCID:: PMC11389369

Abstract Article PDF–6.9M

Select item 113863074.

Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster

Pakeeza Azizpor, Ogadinma K. Okakpu, Sophia C. Parks, Diego Chavez, Fayez Eyabi, Stephanie Martinez-Beltran, Susan Nguyen, Adler R. Dillman

J Lipid Res. 2024 Sep; 65(9): 100608. Published online 2024 Jul 26. doi: 10.1016/j.jlr.2024.100608

PMCID:: PMC11386307

Abstract Article PDF–1.7M

Select item 113827105.

An unusual Toll/MyD88-mediated Drosophila host defence against Talaromyces marneffei

Xiaoyue Wang, Qinglin Qu, Zi Li, Sha Lu, Dominique Ferrandon, Liyan Xi

Fly (Austin) 2024; 18(1): 2398300. Published online 2024 Sep 6. doi: 10.1080/19336934.2024.2398300

PMCID:: PMC11382710

Abstract Article PDF–2.2M

Select item 113751576.

Ingestion of Bacillus cereus spores dampens the immune response to favor bacterial persistence

Salma Hachfi, Alexandra Brun-Barale, Arnaud Fichant, Patrick Munro, Marie-Paule Nawrot-Esposito, Gregory Michel, Raymond Ruimy, Raphaël Rousset, Mathilde Bonis, Laurent Boyer, Armel Gallet

Nat Commun. 2024; 15: 7733. Published online 2024 Sep 4. doi: 10.1038/s41467-024-51689-9

PMCID:: PMC11375157

Abstract Article PDF–4.3M

Select item 113617457.

MprF-mediated immune evasion is necessary for Lactiplantibacillus plantarum resilience in the Drosophila gut during inflammation

Aranzazu Arias-Rojas, Adini Q. Arifah, Georgia Angelidou, Belal Alshaar, Ursula Schombel, Emma Forest, Dagmar Frahm, Volker Brinkmann, Nicole Paczia, Chase L. Beisel, Nicolas Gisch, Igor Iatsenko

PLoS Pathog. 2024 Aug; 20(8): e1012462. Published online 2024 Aug 19. doi: 10.1371/journal.ppat.1012462

PMCID:: PMC11361745

Abstract Article PDF–2.8M

Select item 113492988.

Hosts manipulate lifestyle switch and pathogenicity heterogeneity of opportunistic pathogens in the single-cell resolution

Ziguang Wang, Shuai Li, Sheng Zhang, Tianyu Zhang, Yujie Wu, Anqi Liu, Kui Wang, Xiaowen Ji, Haiqun Cao, Yinglao Zhang, Eng King Tan, Yongcheng Wang, Yirong Wang, Wei Liu

eLife. 2024; 13: RP96789. Published online 2024 Aug 27. doi: 10.7554/eLife.96789

PMCID:: PMC11349298

Abstract Article PDF–20M

Select item 113411009.

High sugar diets can increase susceptibility to bacterial infection in Drosophila melanogaster

Andrea M. Darby, Destiny O. Okoro, Sophia Aredas, Ashley M. Frank, William H. Pearson, Marc S. Dionne, Brian P. Lazzaro

PLoS Pathog. 2024 Aug; 20(8): e1012447. Published online 2024 Aug 12. doi: 10.1371/journal.ppat.1012447

PMCID:: PMC11341100

Abstract Article PDF–2.6M

Select item 1130656010.

Engineered fungus containing a caterpillar gene kills insects rapidly by disrupting their ecto- and endo-microbiomes

Song Hong, Hanchun Gao, Haimin Chen, Chengshu Wang

Commun Biol. 2024; 7: 955. Published online 2024 Aug 7. doi: 10.1038/s42003-024-06670-z

PMCID:: PMC11306560

Abstract Article PDF–2.9M

Select item 1127487311.

Evaluation of Neuroinflammatory Contribution to Neurodegeneration in LRRK2 Drosophila Models

Hoai Nam Nguyen, Grazia Galleri, Antonio Rassu, Cristina Ciampelli, Roberto Bernardoni, Manuela Galioto, Diego Albani, Claudia Crosio, Ciro Iaccarino

Biomedicines. 2024 Jul; 12(7): 1555. Published online 2024 Jul 12. doi: 10.3390/biomedicines12071555

PMCID:: PMC11274873

Abstract Article PDF–2.0M

Select item 1124585212.

The overexpression of DSP1 in neurons induces neuronal dysfunction and neurodegeneration phenotypes in Drosophila

Si-Eun Baek, Younghwi Kwon, Jong-Won Yoon, Hyo-Sung Kim, Jae-Yoon Yang, Dong-Seok Lee, Eunbyul Yeom

Mol Brain. 2024; 17: 43. Published online 2024 Jul 13. doi: 10.1186/s13041-024-01117-2

PMCID:: PMC11245852

Abstract Article PDF–2.7M

Select item 1122935513.

NF-κB factors cooperate with Su(Hw)/E4F1 to balance Drosophila/human immune responses via modulating dynamic expression of miR-210

Hongjian Zhou, Yu Huang, Chaolong Jia, Yujia Pang, Li Liu, Yina Xu, Ping Jin, Jinjun Qian, Fei Ma

Nucleic Acids Res. 2024 Jul 8; 52(12): 6906–6927. Published online 2024 May 14. doi: 10.1093/nar/gkae394

PMCID:: PMC11229355

Abstract Article PDF–2.8M

Select item 1118842914.

Wolbachia endosymbionts in Drosophila regulate the resistance to Zika virus infection in a sex dependent manner

Ghada Tafesh-Edwards, Margarita Kyza Karavioti, Klea Markollari, Dean Bunnell, Stanislava Chtarbanova, Ioannis Eleftherianos

Front Microbiol. 2024; 15: 1380647. Published online 2024 Jun 5. doi: 10.3389/fmicb.2024.1380647

PMCID:: PMC11188429

Abstract Article PDF–1.0M

Select item 1114473015.

Xbp1 targets canonical UPR^ER and non-canonical pathways in separate tissues to promote longevity

Mengjia Li, Haocheng Shou, Guillermo Martínez Corrales, Tatiana Svermova, Alessandra Vieira Franco, Nazif Alic

iScience. 2024 Jun 21; 27(6): 109962. Published online 2024 May 11. doi: 10.1016/j.isci.2024.109962

PMCID:: PMC11144730

Abstract Article PDF–3.9M

Select item 1109728116.

Impairment of the Glial Phagolysosomal System Drives Prion-Like Propagation in a Drosophila Model of Huntington's Disease

Graham H. Davis, Aprem Zaya, Margaret M. Panning Pearce

J Neurosci. 2024 May 15; 44(20): e1256232024. Prepublished online 2024 Apr 8. doi: 10.1523/JNEUROSCI.1256-23.2024

PMCID:: PMC11097281

Abstract Article PDF–34M

Select item 1107442317.

High-fat diets induce inflammatory IMD/NFκB signaling via gut microbiota remodeling in Drosophila

Jun Wang, Jiaojiao Gu, Jianhan Yi, Jie Li, Wen Li, Zongzhao Zhai

Front Cell Infect Microbiol. 2024; 14: 1347716. Published online 2024 Apr 23. doi: 10.3389/fcimb.2024.1347716

PMCID:: PMC11074423

Abstract Article PDF–2.0M

Select item 1104586318.

Reference genes to study the sex-biased expression of genes regulating Drosophila metabolism

Sofie De Groef, Melanie Ribeiro Lopes, Mattias Winant, Emily Rosschaert, Tom Wilms, Lenz Bolckmans, Federica Calevro, Patrick Callaerts

Sci Rep. 2024; 14: 9518. Published online 2024 Apr 25. doi: 10.1038/s41598-024-58863-5

PMCID:: PMC11045863

Abstract Article PDF–5.4M

Select item 1094550819.

DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress

Fabian Hersperger, Tim Meyring, Pia Weber, Chintan Chhatbar, Gianni Monaco, Marc S Dionne, Katrin Paeschke, Marco Prinz, Olaf Groß, Anne-Kathrin Classen, Katrin Kierdorf

eLife. 2024; 12: RP86700. Published online 2024 Jan 8. doi: 10.7554/eLife.86700