PMC Links for GEO Profiles (Select 41752186) - PMC

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108604864.

Constitutive KCC2 Cell- and Synapse-Specifically Regulates NMDA Receptor Activity in the Spinal Cord

Yuying Huang (黄玉莹), Hong Chen (陈红), Jian-Ying Shao (邵建英), Jing-Jing Zhou (周京京), Shao-Rui Chen (陈少瑞), Hui-Lin Pan (潘惠麟)

J Neurosci. 2024 Jan 24; 44(4): e1943232023. doi: 10.1523/JNEUROSCI.1943-23.2023

PMCID:: PMC10860486

Abstract Article PDF–3.3M

Select item 107693505.

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders

Abdelhalim Loukil, Emma Ebright, Akiyoshi Uezu, Yudong Gao, Scott H Soderling, Sarah C. Goetz

Version 1. bioRxiv. Preprint. 2023 Dec 21. doi: 10.1101/2023.12.20.572700

PMCID:: PMC10769350

Abstract Article PDF–11M

Select item 107178396.

Overexpression of neuronal K⁺–Cl⁻ co-transporter enhances dendritic spine plasticity and motor learning

Kayo Nakamura, Andrew John Moorhouse, Dennis Lawrence Cheung, Kei Eto, Ikuko Takeda, Paul Wiers Rozenbroek, Junichi Nabekura

J Physiol Sci. 2019 May; 69(3): 453–463. Published online 2019 Feb 13. doi: 10.1007/s12576-018-00654-5

PMCID:: PMC10717839

Abstract Article PDF–2.4M

Select item 104022867.

BDNF-TrkB signaling pathway-mediated microglial activation induces neuronal KCC2 downregulation contributing to dynamic allodynia following spared nerve injury

Zihan Hu, Xinren Yu, Pei Chen, Keyu Jin, Jing Zhou, Guoxiang Wang, Jiangning Yu, Tong Wu, Yulong Wang, Fuqing Lin, Tingting Zhang, Yun Wang, Xuan Zhao

Mol Pain. 2023; 19: 17448069231185439. Published online 2023 Aug 3. doi: 10.1177/17448069231185439

Correction in:: Mol Pain. 2024; 20: 17448069231222686.

PMCID:: PMC10402286

Abstract Article PDF–2.4M

Select item 102091158.

Silencing KCC2 in mouse dorsal hippocampus compromises spatial and contextual memory

Clémence Simonnet, Manisha Sinha, Marie Goutierre, Imane Moutkine, Stéphanie Daumas, Jean Christophe Poncer

Neuropsychopharmacology. 2023 Jun; 48(7): 1067–1077. Published online 2022 Oct 27. doi: 10.1038/s41386-022-01480-5

PMCID:: PMC10209115

Abstract Article PDF–3.0M

Select item 101855079.

KCC2 downregulation after sciatic nerve injury enhances motor function recovery

Dennis Lawrence Cheung, Takuya Toda, Madoka Narushima, Kei Eto, Chitoshi Takayama, Tatsuko Ooba, Hiroaki Wake, Andrew John Moorhouse, Junichi Nabekura

Sci Rep. 2023; 13: 7871. Published online 2023 May 15. doi: 10.1038/s41598-023-34701-y

PMCID:: PMC10185507

Abstract Article PDF–3.4M

Select item 1018375410.

Expression patterns of NKCC1 in neurons and non-neuronal cells during cortico-hippocampal development

Samu N Kurki, Pavel Uvarov, Alexey S Pospelov, Kalevi Trontti, Antje K Hübner, Rakenduvadhana Srinivasan, Masahiko Watanabe, Iiris Hovatta, Christian A Hübner, Kai Kaila, Mari A Virtanen

Cereb Cortex. 2023 May 15; 33(10): 5906–5923. Published online 2022 Dec 27. doi: 10.1093/cercor/bhac470

PMCID:: PMC10183754

Abstract Article PDF–3.1M

Select item 1016499911.

Conditional deletion of KCC2 impairs synaptic plasticity and both spatial and nonspatial memory

Anna Kreis, Farah Issa, Xavier Yerna, Caren Jabbour, Olivier Schakman, Marie de Clippele, Nicolas Tajeddine, Nathalie Pierrot, Jean-Noël Octave, Roberta Gualdani, Philippe Gailly

Front Mol Neurosci. 2023; 16: 1081657. Published online 2023 Apr 24. doi: 10.3389/fnmol.2023.1081657

PMCID:: PMC10164999

Abstract Article PDF–4.7M

Select item 994532312.

Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex

Yusuke Takezawa, Rachel Langton, Samuel M. Baule, Miriam Bridget Zimmerman, Stephen Baek, Joseph Glykys

Neurobiol Dis. Author manuscript; available in PMC 2023 Mar 1.

Published in final edited form as: Neurobiol Dis. 2023 Mar; 178: 106013. Published online 2023 Jan 25. doi: 10.1016/j.nbd.2023.106013

PMCID:: PMC9945323

Abstract Article PDF–2.3M

Select item 993821613.

Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub

Marc P. Forrest, Marc Dos Santos, Nicolas H. Piguel, Yi-Zhi Wang, Nicole A. Hawkins, Vikram A. Bagchi, Leonardo E. Dionisio, Sehyoun Yoon, Dina Simkin, Maria Dolores Martin-de-Saavedra, Ruoqi Gao, Katherine E. Horan, Alfred L. George, Jr., Mark S. LeDoux, Jennifer A. Kearney, Jeffrey N. Savas, Peter Penzes

Nat Commun. 2023; 14: 825. Published online 2023 Feb 17. doi: 10.1038/s41467-023-36087-x

PMCID:: PMC9938216

Abstract Article PDF–5.3M

Select item 987232114.

Neonatal inflammation increases hippocampal KCC2 expression through methylation-mediated TGF-β1 downregulation leading to impaired hippocampal cognitive function and synaptic plasticity in adult mice

Jing Rong, Yang Yang, Min Liang, Haiquan Zhong, Yingchun Li, Yichao Zhu, Sha Sha, Lei Chen, Rong Zhou

J Neuroinflammation. 2023; 20: 15. Published online 2023 Jan 23. doi: 10.1186/s12974-023-02697-x

PMCID:: PMC9872321

Abstract Article PDF–5.6M

Select item 973996715.

TGF-β2 Regulates Transcription of the K⁺/Cl⁻ Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons

Anastasia Rigkou, Attila Magyar, Jan Manuel Speer, Eleni Roussa

Cells. 2022 Dec; 11(23): 3861. Published online 2022 Nov 30. doi: 10.3390/cells11233861

PMCID:: PMC9739967

Abstract Article PDF–3.4M

Select item 960386016.

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3

Laura Sánchez-Bellver, Andrea Férriz-Gordillo, Marc Carrillo-Pz, Laura Rabanal, Francesc R. Garcia-Gonzalo, Gemma Marfany

Int J Mol Sci. 2022 Oct; 23(20): 12527. Published online 2022 Oct 19. doi: 10.3390/ijms232012527

PMCID:: PMC9603860

Abstract Article PDF–3.4M

Select item 896688717.

Loss of KCC2 in GABAergic Neurons Causes Seizures and an Imbalance of Cortical Interneurons

Kirill Zavalin, Anjana Hassan, Cary Fu, Eric Delpire, Andre H. Lagrange

Front Mol Neurosci. 2022; 15: 826427. Published online 2022 Mar 16. doi: 10.3389/fnmol.2022.826427

PMCID:: PMC8966887

Abstract Article PDF–8.9M

Select item 885092218.

Disruption of KCC2 in Parvalbumin-Positive Interneurons Is Associated With a Decreased Seizure Threshold and a Progressive Loss of Parvalbumin-Positive Interneurons

Tanja Herrmann, Melanie Gerth, Ralf Dittmann, Daniel Pensold, Martin Ungelenk, Lutz Liebmann, Christian A. Hübner

Front Mol Neurosci. 2021; 14: 807090. Published online 2022 Feb 3. doi: 10.3389/fnmol.2021.807090

PMCID:: PMC8850922

Abstract Article PDF–3.1M

Select item 840467219.

Restoration of KCC2 Membrane Localization in Striatal Dopamine D2 Receptor-Expressing Medium Spiny Neurons Rescues Locomotor Deficits in HIV Tat-Transgenic Mice

Aaron J. Barbour, Sara R. Nass, Yun K. Hahn, Kurt F. Hauser, Pamela E. Knapp

ASN Neuro. 2021 Jan-Dec; 13: 17590914211022089. Published online 2021 Aug 26. doi: 10.1177/17590914211022089

PMCID:: PMC8404672

Abstract Article PDF–1.2M

Select item 819131320.

Structural changes in the extracellular loop 2 of the murine KCC2 potassium chloride cotransporter modulate ion transport

Anna-Maria Hartmann, Lifei Fu, Christine Ziegler, Michael Winklhofer, Hans Gerd Nothwang

J Biol Chem. 2021 Jan-Jun; 296: 100793. Published online 2021 May 18. doi: 10.1016/j.jbc.2021.100793

PMCID:: PMC8191313

Abstract Article PDF–3.4M

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