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Items: 20

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
PHLPP isoforms differentially regulate Akt isoforms and AS160 affecting neuronal insulin signaling and insulin resistance via Scribble
Medha Sharma, Chinmoy Sankar Dey
Cell Commun Signal. 2022; 20: 179. Published online 2022 Nov 14. doi: 10.1186/s12964-022-00987-0
PMCID:
PMC9664818
AbstractArticlePDF–3.9M
3.
Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes
Blaz Lupse, Karthika Annamalai, Hazem Ibrahim, Supreet Kaur, Shirin Geravandi, Bhavishya Sarma, Anasua Pal, Sushil Awal, Arundhati Joshi, Sahar Rafizadeh, Murali Krishna Madduri, Mona Khazaei, Huan Liu, Ting Yuan, Wei He, Kanaka Durga Devi Gorrepati, Zahra Azizi, Qi Qi, Keqiang Ye, Jose Oberholzer, Kathrin Maedler, Amin Ardestani
Cell Rep. Author manuscript; available in PMC 2021 Sep 6.
Published in final edited form as: Cell Rep. 2021 Aug 3; 36(5): 109490. doi: 10.1016/j.celrep.2021.109490
PMCID:
PMC8421018
AbstractArticlePDF–3.1M
4.
Colonic Epithelial PHLPP2 Deficiency Promotes Colonic Epithelial Pyroptosis by Activating the NF-κB Signaling Pathway
De-feng Li, Xin Chang, Jiu-long Zhao, Xuan-min Chen, Zheng-lei Xu, Ding-guo Zhang, Ben-hua Wu, Li-sheng Wang, Yu Bai, Jun Yao
Oxid Med Cell Longev. 2021; 2021: 5570731. Published online 2021 Aug 6. doi: 10.1155/2021/5570731
PMCID:
PMC8363454
AbstractArticlePDF–4.6M
5.
Adipocyte PHLPP2 inhibition prevents obesity-induced fatty liver
KyeongJin Kim, Jin Ku Kang, Young Hoon Jung, Sang Bae Lee, Raffaela Rametta, Paola Dongiovanni, Luca Valenti, Utpal B. Pajvani
Nat Commun. 2021; 12: 1822. Published online 2021 Mar 23. doi: 10.1038/s41467-021-22106-2
PMCID:
PMC7988046
AbstractArticlePDF–2.1M
6.
GORAB promotes embryonic lung maturation through antagonizing AKT phosphorylation, versican expression and mesenchymal cell migration
Ying Liu, Xi Chen, Yeon Ja Choi, Ning Yang, Zhongya Song, Elizabeth R. Snedecor, Wei Liang, Elaine Lai-Han Leung, Lianfeng Zhang, Chuan Qin, Jiang Chen
FASEB J. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: FASEB J. 2020 Apr; 34(4): 4918–4933. Published online 2020 Feb 18. doi: 10.1096/fj.201902075R
PMCID:
PMC7319104
AbstractArticlePDF–1.7M
7.
The PHLPP2 phosphatase is a druggable driver of prostate cancer progression
Dawid G. Nowak, Ksenya Cohen Katsenelson, Kaitlin E. Watrud, Muhan Chen, Grinu Mathew, Vincent D. D’Andrea, Matthew F. Lee, Manojit Mosur Swamynathan, Irene Casanova-Salas, Megan C. Jibilian, Caroline L. Buckholtz, Alexandra J. Ambrico, Chun-Hao Pan, John E. Wilkinson, Alexandra C. Newton, Lloyd C. Trotman
J Cell Biol. 2019 Jun 28; 218(6): 1943–1957. Published online 2019 May 15. doi: 10.1083/jcb.201902048
PMCID:
PMC6548123
AbstractArticlePDF–3.7M
8.
Degradation of PHLPP2 by KCTD17, via a Glucagon-dependent Pathway, Promotes Hepatic Steatosis
KyeongJin Kim, Dongryeol Ryu, Paola Dongiovanni, Lale Ozcan, Shruti Nayak, Beatrix Ueberheide, Luca Valenti, Johan Auwerx, Utpal B. Pajvani
Gastroenterology. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: Gastroenterology. 2017 Dec; 153(6): 1568–1580.e10. Published online 2017 Aug 30. doi: 10.1053/j.gastro.2017.08.039
PMCID:
PMC5705280
AbstractArticlePDF–1.7M
9.
Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C
Xiaopeng Xiong, Xin Li, Yang-An Wen, Tianyan Gao
J Biol Chem. 2016 Nov 25; 291(48): 25167–25178. Published online 2016 Oct 19. doi: 10.1074/jbc.M116.740639
PMCID:
PMC5122783
AbstractArticlePDF–3.4M
10.
Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs
Maoyi Lai, Alicia Gonzalez-Martin, Anthony B. Cooper, Hiroyo Oda, Hyun Yong Jin, Jovan Shepherd, Linling He, Jiang Zhu, David Nemazee, Changchun Xiao
Nat Commun. 2016; 7: 12207. Published online 2016 Aug 2. doi: 10.1038/ncomms12207
PMCID:
PMC4974641
AbstractArticlePDF–2.4M
11.
Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis
Yang-An Wen, Xin Li, Tatiana Goretsky, Heidi L. Weiss, Terrence A. Barrett, Tianyan Gao
Biochim Biophys Acta. Author manuscript; available in PMC 2016 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Oct; 1852(10 0 0): 2013–2023. Published online 2015 Jul 15. doi: 10.1016/j.bbadis.2015.07.012
PMCID:
PMC4554835
AbstractArticlePDF–1.9M
12.
Myc drives Pten/p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2
Dawid G. Nowak, Hyejin Cho, Tali Herzka, Kaitlin Watrud, Daniel V. DeMarco, Victoria M. Y. Wang, Serif Senturk, Christof Fellmann, David Ding, Tumas Beinortas, David Kleinman, Muhan Chen, Raffaella Sordella, John E. Wilkinson, Mireia Castillo-Martin, Carlos Cordon-Cardo, Brian D. Robinson, Lloyd C. Trotman
Cancer Discov. Author manuscript; available in PMC 2015 Dec 1.
Published in final edited form as: Cancer Discov. 2015 Jun; 5(6): 636–651. Published online 2015 Mar 31. doi: 10.1158/2159-8290.CD-14-1113
PMCID:
PMC4456272
AbstractArticlePDF–2.9M
13.
PHLPP is a Negative Regulator of RAF1 that Reduces Colorectal Cancer Cell Motility and Prevents Tumor Progression in Mice
Xin Li, Payton D. Stevens, Jianyu Liu, Haihua Yang, Wei Wang, Chi Wang, Zheng Zeng, Micheal D. Schmidt, Mike Yang, Eun Y. Lee, Tianyan Gao
Gastroenterology. Author manuscript; available in PMC 2015 May 1.
Published in final edited form as: Gastroenterology. 2014 May; 146(5): 1301–1312.e10. Published online 2014 Feb 11. doi: 10.1053/j.gastro.2014.02.003
PMCID:
PMC3992173
AbstractArticlePDF–3.2M
14.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
15.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
16.
Genomic Analysis of Mouse Retinal Development
Seth Blackshaw, Sanjiv Harpavat, Jeff Trimarchi, Li Cai, Haiyan Huang, Winston P Kuo, Griffin Weber, Kyungjoon Lee, Rebecca E Fraioli, Seo-Hee Cho, Rachel Yung, Elizabeth Asch, Lucila Ohno-Machado, Wing H Wong, Constance L Cepko
PLoS Biol. 2004 Sep; 2(9): e247. Published online 2004 Jun 29. doi: 10.1371/journal.pbio.0020247
PMCID:
PMC439783
AbstractArticlePDF–975K
17.
RIKEN Integrated Sequence Analysis (RISA) System—384-Format Sequencing Pipeline with 384 Multicapillary Sequencer
Kazuhiro Shibata, Masayoshi Itoh, Katsunori Aizawa, Sumiharu Nagaoka, Nobuya Sasaki, Piero Carninci, Hideaki Konno, Junichi Akiyama, Katsuo Nishi, Tokuji Kitsunai, Hideo Tashiro, Mari Itoh, Noriko Sumi, Yoshiyuki Ishii, Shin Nakamura, Makoto Hazama, Tsutomu Nishine, Akira Harada, Rintaro Yamamoto, Hiroyuki Matsumoto, Sumito Sakaguchi, Takashi Ikegami, Katsuya Kashiwagi, Syuji Fujiwake, Kouji Inoue, Yoshiyuki Togawa, Masaki Izawa, Eiji Ohara, Masanori Watahiki, Yuko Yoneda, Tomokazu Ishikawa, Kaori Ozawa, Takumi Tanaka, Shuji Matsuura, Jun Kawai, Yasushi Okazaki, Masami Muramatsu, Yorinao Inoue, Akira Kira, Yoshihide Hayashizaki
Genome Res. 2000 Nov; 10(11): 1757–1771. doi: 10.1101/gr.152600
PMCID:
PMC310992
AbstractArticlePDF–3.4M
18.
Normalization and Subtraction of Cap-Trapper-Selected cDNAs to Prepare Full-Length cDNA Libraries for Rapid Discovery of New Genes
Piero Carninci, Yuko Shibata, Norihito Hayatsu, Yuichi Sugahara, Kazuhiro Shibata, Masayoshi Itoh, Hideaki Konno, Yasushi Okazaki, Masami Muramatsu, Yoshihide Hayashizaki
Genome Res. 2000 Oct; 10(10): 1617–1630. doi: 10.1101/gr.145100
PMCID:
PMC310980
AbstractArticlePDF–1.4M
19.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K
20.
Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray
Tetsuya S. Tanaka, Saied A. Jaradat, Meng K. Lim, George J. Kargul, Xiaohong Wang, Marija J. Grahovac, Serafino Pantano, Yuri Sano, Yulan Piao, Ramaiah Nagaraja, Hirofumi Doi, William H. Wood, III, Kevin G. Becker, Minoru S. H. Ko
Proc Natl Acad Sci U S A. 2000 Aug 1; 97(16): 9127–9132. doi: 10.1073/pnas.97.16.9127
PMCID:
PMC16833
AbstractArticlePDF–847K

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