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Select item 101640981.

Transcriptional control of nucleus accumbens neuronal excitability by Retinoid X Receptor Alpha tunes sensitivity to drug rewards

Arthur Godino, Marine Salery, Romain Durand-de Cuttoli, Molly S. Estill, Leanne M. Holt, Rita Futamura, Caleb J. Browne, Philipp Mews, Peter J. Hamilton, Rachael L. Neve, Li Shen, Scott J. Russo, Eric J. Nestler

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1453–1467.e7. Published online 2023 Mar 7. doi: 10.1016/j.neuron.2023.02.013

PMCID:: PMC10164098

Abstract Article PDF–2.3M

Select item 96369062.

Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome

Santiago Vernia, Alexandra Lee, Norman J. Kennedy, Myoung Sook Han, Marta Isasa, Julie Cavanagh-Kyros, Armanda Roy, Aafreen Syed, Shanzah Chaudhry, Yvonne J. K. Edwards, Steven P. Gygi, Guangping Gao, Roger J. Davis

Proc Natl Acad Sci U S A. 2022 Nov 1; 119(44): e2210434119. Published online 2022 Oct 25. doi: 10.1073/pnas.2210434119

PMCID:: PMC9636906

Abstract Article PDF–1.7M

Select item 90181193.

Regulation of Prefrontal Patterning and Connectivity by Retinoic Acid

Mikihito Shibata, Kartik Pattabiraman, Belen Lorente-Galdos, David Andrijevic, Suel-Kee Kim, Navjot Kaur, Sydney K. Muchnik, Xiaojun Xing, Gabriel Santpere, Andre M. M. Sousa, Nenad Sestan

Nature. Author manuscript; available in PMC 2022 Apr 19.

Published in final edited form as: Nature. 2021 Oct; 598(7881): 483–488. Published online 2021 Oct 1. doi: 10.1038/s41586-021-03953-x

PMCID:: PMC9018119

Abstract Article PDF–12M

Select item 88045614.

RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells

Orsola di Martino, Margaret A. Ferris, Gayla Hadwiger, Soyi Sarkar, Anh Vu, María P. Menéndez-Gutiérrez, Mercedes Ricote, John S. Welch

Haematologica. 2022 Feb 1; 107(2): 417–426. Published online 2021 Jun 17. doi: 10.3324/haematol.2021.278603

PMCID:: PMC8804561

Abstract Article PDF–1.6M

Select item 84923265.

Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization

Yan Yin, Meade E. Haller, Sangappa B. Chadchan, Ramakrishna Kommagani, Liang Ma

JCI Insight. 2021 Sep 8; 6(17): e150254. Published online 2021 Sep 8. doi: 10.1172/jci.insight.150254

PMCID:: PMC8492326

Abstract Article PDF–3.4M

Select item 79387706.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78541827.

T-Cell Death-Associated Gene 51 Is a Novel Negative Regulator of PPARγ That Inhibits PPARγ-RXRα Heterodimer Formation in Adipogenesis

Sumi Kim, Nari Lee, Eui-Soon Park, Hyeongseok Yun, Tae-Uk Ha, Hyoeun Jeon, Jiyeon Yu, Seunga Choi, Bongjin Shin, Jungeun Yu, Sang Dal Rhee, Yongwon Choi, Jaerang Rho

Mol Cells. 2021 Jan 31; 44(1): 1–12. Published online 2020 Dec 18. doi: 10.14348/molcells.2020.0143

PMCID:: PMC7854182

Abstract Article PDF–996K

Select item 78171208.

Mechanistic insights into the synergistic activation of the RXR–PXR heterodimer by endocrine disruptor mixtures

Vanessa Delfosse, Tiphaine Huet, Deborah Harrus, Meritxell Granell, Maxime Bourguet, Caroline Gardia-Parège, Barbara Chiavarina, Marina Grimaldi, Sébastien Le Mével, Pauline Blanc, David Huang, Jakub Gruszczyk, Barbara Demeneix, Sarah Cianférani, Jean-Baptiste Fini, Patrick Balaguer, William Bourguet

Proc Natl Acad Sci U S A. 2021 Jan 5; 118(1): e2020551118. Published online 2020 Dec 28. doi: 10.1073/pnas.2020551118

PMCID:: PMC7817120

Abstract Article PDF–2.0M

Select item 73031999.

Dissecting myogenin-mediated retinoid X receptor signaling in myogenic differentiation

Saadia Khilji, Munerah Hamed, Jihong Chen, Qiao Li

Commun Biol. 2020; 3: 315. Published online 2020 Jun 18. doi: 10.1038/s42003-020-1043-9

PMCID:: PMC7303199

Abstract Article PDF–2.3M

Select item 719100010.

Mature myelin maintenance requires Qki to coactivate PPARβ-RXRα–mediated lipid metabolism

Xin Zhou, Chenxi He, Jiangong Ren, Congxin Dai, Sharon R. Stevens, Qianghu Wang, Daniel Zamler, Takashi Shingu, Liang Yuan, Chythra R. Chandregowda, Yunfei Wang, Visweswaran Ravikumar, Arvind U.K. Rao, Feng Zhou, Hongwu Zheng, Matthew N. Rasband, Yiwen Chen, Fei Lan, Amy B. Heimberger, Benjamin M. Segal, Jian Hu

J Clin Invest. 2020 May 1; 130(5): 2220–2236. Published online 2020 Mar 23. doi: 10.1172/JCI131800

PMCID:: PMC7191000

Abstract Article PDF–16M

Select item 712516111.

RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression

María Casanova-Acebes, María Piedad Menéndez-Gutiérrez, Jesús Porcuna, Damiana Álvarez-Errico, Yonit Lavin, Ana García, Soma Kobayashi, Jessica Le Berichel, Vanessa Núñez, Felipe Were, Daniel Jiménez-Carretero, Fátima Sánchez-Cabo, Miriam Merad, Mercedes Ricote

Nat Commun. 2020; 11: 1655. Published online 2020 Apr 3. doi: 10.1038/s41467-020-15371-0

PMCID:: PMC7125161

Abstract Article PDF–3.3M

Select item 704205112.

Brain cleanup as a potential target for post-stroke recovery: the role of RXR in phagocytes

Shun-Ming Ting, Xiurong Zhao, Guanghua Sun, Lidiya Obertas, Mercedes Ricote, Jaroslaw Aronowski

Stroke. Author manuscript; available in PMC 2021 Mar 1.

Published in final edited form as: Stroke. 2020 Mar; 51(3): 958–966. Published online 2020 Jan 9. doi: 10.1161/STROKEAHA.119.027315

PMCID:: PMC7042051

Abstract Article PDF–1.5M

Select item 675938313.

A phosphorylation-deficient mutant of retinoid X receptor α at Thr167 alters fasting response and energy metabolism in mice

Tatsuya Sueyoshi, Tsutomu Sakuma, Sawako Shindo, Muluneh Fashe, Tomohiko Kanayama, Manas Ray, Rick Moore, Masahiko Negishi

Lab Invest. Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Lab Invest. 2019 Oct; 99(10): 1470–1483. Published online 2019 May 31. doi: 10.1038/s41374-019-0266-1

PMCID:: PMC6759383

Abstract Article PDF–1.6M

Select item 667091814.

Identification of a Novel Nurr1-Interacting Protein

Yu Luo, Feng Xing, Rita Guiliano, Howard J. Federoff

J Neurosci. 2008 Sep 10; 28(37): 9277–9286. doi: 10.1523/JNEUROSCI.3021-08.2008

PMCID:: PMC6670918

Abstract Article PDF–861K

Select item 650686215.

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development

Elisa De Franco, Rachel A. Watson, Wolfgang J. Weninger, Chi C. Wong, Sarah E. Flanagan, Richard Caswell, Angela Green, Catherine Tudor, Christopher J. Lelliott, Stefan H. Geyer, Barbara Maurer-Gesek, Lukas F. Reissig, Hana Lango Allen, Almuth Caliebe, Reiner Siebert, Paul Martin Holterhus, Asma Deeb, Fabrice Prin, Robert Hilbrands, Harry Heimberg, Sian Ellard, Andrew T. Hattersley, Inês Barroso

Am J Hum Genet. 2019 May 2; 104(5): 985–989. Published online 2019 Apr 18. doi: 10.1016/j.ajhg.2019.03.018

PMCID:: PMC6506862

Abstract Article PDF–1.2M

Select item 644377516.

Oncogenic potential of truncated RXRα during colitis-associated colorectal tumorigenesis by promoting IL-6-STAT3 signaling

Xiaohong Ye, Hua Wu, Luoyan Sheng, Yi-xin Liu, Fang Ye, Mo Wang, Hu Zhou, Ying Su, Xiao-kun Zhang

Nat Commun. 2019; 10: 1463. Published online 2019 Apr 1. doi: 10.1038/s41467-019-09375-8

PMCID:: PMC6443775

Abstract Article PDF–3.0M

Select item 642805017.

The Evf2 ultraconserved enhancer lncRNA functionally and spatially organizes multi-megabase distant genes in developing forebrain

Ivelisse Cajigas, Abhijit Chakraborty, Kelsey R. Swyter, Hao Luo, Monique Bastidas, Maximilliano Nigro, Elizabeth R. Morris, Sean Chen, Michael J. W. VanGompel, David Leib, Sara J. Kohtz, Marco Martina, Sooky Koh, Ferhat Ay, Jhumku D. Kohtz

Mol Cell. Author manuscript; available in PMC 2019 Sep 20.

Published in final edited form as: Mol Cell. 2018 Sep 20; 71(6): 956–972.e9. Published online 2018 Aug 23. doi: 10.1016/j.molcel.2018.07.024

PMCID:: PMC6428050

Abstract Article PDF–2.0M

Select item 638138818.

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System

Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund

Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005

PMCID:: PMC6381388

Abstract Article

Select item 628410819.

Retinoic Acid Receptor RARα-Dependent Synaptic Signaling Mediates Homeostatic Synaptic Plasticity at the Inhibitory Synapses of Mouse Visual Cortex

Lei R. Zhong, Xin Chen, Esther Park, Thomas C. Südhof, Lu Chen

J Neurosci. 2018 Dec 5; 38(49): 10454–10466. doi: 10.1523/JNEUROSCI.1133-18.2018

PMCID:: PMC6284108

Abstract Article PDF–1.3M

Select item 600911420.

Transcriptional Modulations by RXR Agonists Are Only Partially Subordinated to PPARα Signaling and Attest Additional, Organ-Specific, Molecular Cross-Talks

Pascal G. P. Martin, Frédéric Lasserre, Cécile Calleja, Armelle Van Es, Alain Roulet, Didier Concordet, Michela Cantiello, Romain Barnouin, Béatrice Gauthier, Thierry Pineau

Gene Expr. 2005; 12(3): 177–192. Published online 2018 Jun 20. doi: 10.3727/000000005783992098

PMCID:: PMC6009114

Abstract Article PDF–447K

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