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Items: 1 to 20 of 27

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Regulation of microtubule nucleation in mouse bone marrow-derived mast cells by ARF GTPase-activating protein GIT2
Vadym Sulimenko, Vladimíra Sládková, Tetyana Sulimenko, Eduarda Dráberová, Věra Vosecká, Lubica Dráberová, Omar Skalli, Pavel Dráber
Front Immunol. 2024; 15: 1321321. Published online 2024 Feb 2. doi: 10.3389/fimmu.2024.1321321
PMCID:
PMC10870779
AbstractArticlePDF–4.7M
3.
The RXFP3 receptor is functionally associated with cellular responses to oxidative stress and DNA damage
Jaana van Gastel, Hanne Leysen, Paula Santos-Otte, Jhana O. Hendrickx, Abdelkrim Azmi, Bronwen Martin, Stuart Maudsley
Aging (Albany NY) 2019 Dec 15; 11(23): 11268–11313. Published online 2019 Dec 3. doi: 10.18632/aging.102528
PMCID:
PMC6932917
AbstractArticlePDF–4.3M
4.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
5.
ATG5 is required for B cell polarization and presentation of particulate antigens
Florent Arbogast, Johan Arnold, Philippe Hammann, Lauriane Kuhn, Johana Chicher, Diane Murera, Justine Weishaar, Sylviane Muller, Jean-Daniel Fauny, Frédéric Gros
Autophagy. 2019; 15(2): 280–294. Published online 2018 Sep 22. doi: 10.1080/15548627.2018.1516327
PMCID:
PMC6333460
AbstractArticlePDF–2.7M
6.
Spatio-temporal profile of postynaptic interactomes integrates components of complex brain disorders
Jing Li, Wangshu Zhang, Hui Yang, Daniel P. Howrigan, Brent Wilkinson, Tade Souaiaia, Oleg V. Evgrafov, Giulio Genovese, Veronica A. Clementel, Jennifer C. Tudor, Ted Abel, James A. Knowles, Benjamin M. Neale, Kai Wang, Fengzhu Sun, Marcelo P. Coba
Nat Neurosci. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Nat Neurosci. 2017 Aug; 20(8): 1150–1161. Published online 2017 Jun 26. doi: 10.1038/nn.4594
PMCID:
PMC5645082
AbstractArticlePDF–2.3M
7.
Genomic deletion of GIT2 induces a premature age-related thymic dysfunction and systemic immune system disruption
Sana Siddiqui, Ana Lustig, Arnell Carter, Mathavi Sankar, Caitlin M. Daimon, Richard T. Premont, Harmonie Etienne, Jaana van Gastel, Abdelkrim Azmi, Jonathan Janssens, Kevin G. Becker, Yongqing Zhang, William Wood, III, Elin Lehrmann, James G. Martin, Bronwen Martin, Dennis D. Taub, Stuart Maudsley
Aging (Albany NY) 2017 Mar; 9(3): 706–730. Published online 2017 Mar 4. doi: 10.18632/aging.101185
PMCID:
PMC5391227
AbstractArticlePDF–3.1M
8.
Targeting CAG repeat RNAs reduces Huntington’s disease phenotype independently of huntingtin levels
Laura Rué, Mónica Bañez-Coronel, Jordi Creus-Muncunill, Albert Giralt, Rafael Alcalá-Vida, Gartze Mentxaka, Birgit Kagerbauer, M. Teresa Zomeño-Abellán, Zeus Aranda, Veronica Venturi, Esther Pérez-Navarro, Xavier Estivill, Eulàlia Martí
J Clin Invest. 2016 Nov 1; 126(11): 4319–4330. Published online 2016 Oct 10. doi: 10.1172/JCI83185
PMCID:
PMC5096913
AbstractArticlePDF–1.2M
9.
GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging
Bronwen Martin, Wayne Chadwick, Jonathan Janssens, Richard T. Premont, Robert Schmalzigaug, Kevin G. Becker, Elin Lehrmann, William H. Wood, Yongqing Zhang, Sana Siddiqui, Sung-Soo Park, Wei-na Cong, Caitlin M. Daimon, Stuart Maudsley
Front Endocrinol (Lausanne) 2015; 6: 191. Published online 2016 Jan 18. doi: 10.3389/fendo.2015.00191
PMCID:
PMC4716144
AbstractArticlePDF–13M
10.
Presynaptic deletion of GIT proteins results in increased synaptic strength at a mammalian central synapse
Mónica S. Montesinos, Wei Dong, Kevin Goff, Brati Das, Debbie Guerrero-Given, Robert Schmalzigaug, Richard T. Premont, Rachel Satterfield, Naomi Kamasawa, Samuel M. Young, Jr
Neuron. Author manuscript; available in PMC 2016 Dec 2.
Published in final edited form as: Neuron. 2015 Dec 2; 88(5): 918–925. doi: 10.1016/j.neuron.2015.10.042
PMCID:
PMC4672385
AbstractArticlePDF–1.1M
11.
GIT2 deficiency attenuates concanavalin A-induced hepatitis in mice
Yu-E Hao, Dong-Fang He, Rong-Hua Yin, Hui Chen, Jian Wang, Shao-Xia Wang, Yi-Qun Zhan, Chang-Hui Ge, Chang-Yan Li, Miao Yu, Xiao-Ming Yang
FEBS Open Bio. 2015; 5: 688–704. Published online 2015 Aug 11. doi: 10.1016/j.fob.2015.08.005
PMCID:
PMC4556731
AbstractArticlePDF–4.4M
12.
Nuclear GIT2 Is an ATM Substrate and Promotes DNA Repair
Daoyuan Lu, Huan Cai, Sung-Soo Park, Sana Siddiqui, Richard T. Premont, Robert Schmalzigaug, Manikandan Paramasivam, Michael Seidman, Ionoa Bodogai, Arya Biragyn, Caitlin M. Daimon, Bronwen Martin, Stuart Maudsley
Mol Cell Biol. 2015 Apr; 35(7): 1081–1096. Prepublished online 2015 Jan 20. Published online 2015 Mar 10. doi: 10.1128/MCB.01432-14
Correction in:
Mol Cell Biol. 2017 Sep 1; 37(17): e00310-17.
PMCID:
PMC4355538
AbstractArticlePDF–5.1M
13.
The GTPase-activating protein GIT2 protects against colitis by negatively regulating Toll-like receptor signaling
Juncheng Wei, Chao Wei, Min Wang, Xiao Qiu, Yang Li, Yanzhi Yuan, Chaozhi Jin, Ling Leng, Jian Wang, Xiaoming Yang, Fuchu He
Proc Natl Acad Sci U S A. 2014 Jun 17; 111(24): 8883–8888. Published online 2014 May 30. doi: 10.1073/pnas.1309218111
PMCID:
PMC4066529
AbstractArticlePDF–1.6M
14.
Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes
Jacqueline K. White, Anna-Karin Gerdin, Natasha A. Karp, Ed Ryder, Marija Buljan, James N. Bussell, Jennifer Salisbury, Simon Clare, Neil J. Ingham, Christine Podrini, Richard Houghton, Jeanne Estabel, Joanna R. Bottomley, David G. Melvin, David Sunter, Niels C. Adams, The Sanger Institute Mouse Genetics Project, David Tannahill, Darren W. Logan, Daniel G. MacArthur, Jonathan Flint, Vinit B. Mahajan, Stephen H. Tsang, Ian Smyth, Fiona M. Watt, William C. Skarnes, Gordon Dougan, David J. Adams, Ramiro Ramirez-Solis, Allan Bradley, Karen P. Steel
Cell. 2013 Jul 18; 154(2): 452–464. doi: 10.1016/j.cell.2013.06.022
PMCID:
PMC3717207
AbstractArticlePDF–3.4M
15.
Regulation of thymocyte positive selection and motility by GIT2
Hyewon Phee, Ivan Dzhagalov, Marianne Mollenauer, Yana Wang, Darrell J. Irvine, Ellen Robey, Arthur Weiss
Nat Immunol. Author manuscript; available in PMC 2013 Apr 9.
Published in final edited form as: Nat Immunol. 2010 Jun; 11(6): 503–511. Published online 2010 May 2. doi: 10.1038/ni.1868
PMCID:
PMC3620668
AbstractArticlePDF–2.9M
16.
Transcription factor Foxp3 and its protein partners form a complex regulatory network
Dipayan Rudra, Paul deRoos, Ashutosh Chaudhry, Rachel Niec, Aaron Arvey, Robert M. Samstein, Christina Leslie, Scott A. Shaffer, David R. Goodlett, Alexander Y. Rudensky
Nat Immunol. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: Nat Immunol. 2012 Oct; 13(10): 1010–1019. Published online 2012 Aug 26. doi: 10.1038/ni.2402
PMCID:
PMC3448012
AbstractArticlePDF–2.6M
17.
The Cytoskeletal Regulatory Scaffold Protein GIT2 Modulates Mesenchymal Stem Cell Differentiation and Osteoblastogenesis
Xiaojuan Wang, Shaoxi Liao, Erik R. Nelson, Robert Schmalzigaug, Robert F. Spurney, Farshid Guilak, Richard T. Premont, Diane Gesty-Palmer
Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Aug 24.
Published in final edited form as: Biochem Biophys Res Commun. 2012 Aug 24; 425(2): 407–412. Published online 2012 Jul 27. doi: 10.1016/j.bbrc.2012.07.111
PMCID:
PMC3432571
AbstractArticlePDF–1.0M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Paxillin-Kinase-Linker Tyrosine Phosphorylation Regulates Directional Cell Migration
Jianxin A. Yu, Nicholas O. Deakin, Christopher E. Turner
Mol Biol Cell. 2009 Nov 15; 20(22): 4706–4719. doi: 10.1091/mbc.E09-07-0548
PMCID:
PMC2777101
AbstractArticlePDF–3.7M
20.
Anxiety-like behaviors in mice lacking GIT2
Robert Schmalzigaug, Ramona M. Rodriguiz, Lindsey E. Phillips, Collin E. Davidson, William C. Wetsel, Richard T. Premont
Neurosci Lett. Author manuscript; available in PMC 2010 Feb 20.
Published in final edited form as: Neurosci Lett. 2009 Feb 20; 451(2): 156–161. Published online 2008 Dec 24. doi: 10.1016/j.neulet.2008.12.034
PMCID:
PMC2648396
AbstractArticlePDF–1.3M

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