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Select item 98992441.

Parkinsonism mutations in DNAJC6 cause lipid defects and neurodegeneration that are rescued by Synj1

Julie Jacquemyn, Sabine Kuenen, Jef Swerts, Benjamin Pavie, Vinoy Vijayan, Ayse Kilic, Dries Chabot, Yu-Chun Wang, Nils Schoovaerts, Nikky Corthout, Patrik Verstreken

NPJ Parkinsons Dis. 2023; 9: 19. Published online 2023 Feb 4. doi: 10.1038/s41531-023-00459-3

PMCID:: PMC9899244

Abstract Article PDF–2.4M

Select item 96729662.

Parkinson disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila

Tsuyoshi Inoshita, Jun-Yi Liu, Daisuke Taniguchi, Ryota Ishii, Kahori Shiba-Fukushima, Nobutaka Hattori, Yuzuru Imai

iScience. 2022 Dec 22; 25(12): 105476. Published online 2022 Nov 2. doi: 10.1016/j.isci.2022.105476

PMCID:: PMC9672966

Abstract Article PDF–5.0M

Select item 92426473.

Hypoxia controls plasma membrane targeting of polarity proteins by dynamic turnover of PI4P and PI(4,5)P2

Juan Lu, Wei Dong, Gerald R Hammond, Yang Hong

eLife. 2022; 11: e79582. Published online 2022 Jun 9. doi: 10.7554/eLife.79582

PMCID:: PMC9242647

Abstract Article PDF–8.2M

Select item 86698344.

Tumor–host interactions through the lens of Drosophila

David Bilder, Katy Ong, Tsai-Ching Hsi, Kavya Adiga, Jung Kim

Nat Rev Cancer. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Rev Cancer. 2021 Nov; 21(11): 687–700. Published online 2021 Aug 13. doi: 10.1038/s41568-021-00387-5

PMCID:: PMC8669834

Abstract Article PDF–385K

Select item 86644555.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 84918766.

Minibrain kinase and calcineurin coordinate activity-dependent bulk endocytosis through synaptojanin

Yi-Jheng Peng, Junhua Geng, Ying Wu, Cristian Pinales, Jennifer Langen, Yen-Ching Chang, Christopher Buser, Karen T. Chang

J Cell Biol. 2021 Dec 6; 220(12): e202011028. Published online 2021 Oct 1. doi: 10.1083/jcb.202011028

PMCID:: PMC8491876

Abstract Article PDF–7.6M

Select item 80422707.

Comprehensive Identification and Alternative Splicing of Microexons in Drosophila

Ting-Lin Pang, Zhan Ding, Shao-Bo Liang, Liang Li, Bei Zhang, Yu Zhang, Yu-Jie Fan, Yong-Zhen Xu

Front Genet. 2021; 12: 642602. Published online 2021 Mar 30. doi: 10.3389/fgene.2021.642602

PMCID:: PMC8042270

Abstract Article PDF–3.6M

Select item 78942608.

Investigating rare and ultrarare epilepsy syndromes with Drosophila models

Paul Lasko, Kevin Lüthy

Fac Rev. 2021; 10: 10. Published online 2021 Jan 29. doi: 10.12703/r/10-10

PMCID:: PMC7894260

Abstract Article PDF–2.9M

Select item 77719639.

A genome engineering resource to uncover principles of cellular organization and tissue architecture by lipid signaling

Deepti Trivedi, Vinitha CM, Karishma Bisht, Vishnu Janardan, Awadhesh Pandit, Bishal Basak, Shwetha H, Navyashree Ramesh, Padinjat Raghu

eLife. 2020; 9: e55793. Published online 2020 Dec 15. doi: 10.7554/eLife.55793

PMCID:: PMC7771963

Abstract Article PDF–1.6M

Select item 774842410.

A positive feedback loop between Flower and PI(4,5)P₂ at periactive zones controls bulk endocytosis in Drosophila

Tsai-Ning Li, Yu-Jung Chen, Ting-Yi Lu, You-Tung Wang, Hsin-Chieh Lin, Chi-Kuang Yao

eLife. 2020; 9: e60125. Published online 2020 Dec 10. doi: 10.7554/eLife.60125

PMCID:: PMC7748424

Abstract Article PDF–5.1M

Select item 759449911.

A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux

Elizabeth A. Allen, Clelia Amato, Tina M. Fortier, Panagiotis Velentzas, Will Wood, Eric H. Baehrecke

J Cell Biol. 2020 Nov 2; 219(11): e201909073. Published online 2020 Sep 11. doi: 10.1083/jcb.201909073

PMCID:: PMC7594499

Abstract Article PDF–8.3M

Select item 750397312.

Investigating Developmental and Epileptic Encephalopathy Using Drosophila melanogaster

Akari Takai, Masamitsu Yamaguchi, Hideki Yoshida, Tomohiro Chiyonobu

Int J Mol Sci. 2020 Sep; 21(17): 6442. Published online 2020 Sep 3. doi: 10.3390/ijms21176442

PMCID:: PMC7503973

Abstract Article PDF–1.6M

Select item 696157813.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 692043414.

The CHD Protein, Kismet, is Important for the Recycling of Synaptic Vesicles during Endocytosis

Nina K. Latcheva, Taylor L. Delaney, Jennifer M. Viveiros, Rachel A. Smith, Kelsey M. Bernard, Benjamin Harsin, Daniel R. Marenda, Faith L. W. Liebl

Sci Rep. 2019; 9: 19368. Published online 2019 Dec 18. doi: 10.1038/s41598-019-55900-6

PMCID:: PMC6920434

Abstract Article PDF–8.0M

Select item 650784415.

Disease model organism for Parkinson disease: Drosophila melanogaster

Binod Aryal, Youngseok Lee

BMB Rep. 2019 Apr; 52(4): 250–258. Published online 2019 Apr 30. doi: 10.5483/BMBRep.2019.52.4.204

PMCID:: PMC6507844

Abstract Article PDF–838K

Select item 607860416.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352