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Select item 109457071.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 95260662.

The RNA-binding protein Swm is critical for Drosophila melanogaster intestinal progenitor cell maintenance

Ishara S Ariyapala, Kasun Buddika, Heather A Hundley, Brian R Calvi, Nicholas S Sokol

Genetics. 2022 Oct; 222(2): iyac099. Published online 2022 Jun 28. doi: 10.1093/genetics/iyac099

PMCID:: PMC9526066

Abstract Article PDF–1.4M

Select item 94367523.

Leishmania amazonensis sabotages host cell SUMOylation for intracellular survival

Kendi Okuda, Miriam Maria Silva Costa Franco, Ari Yasunaga, Ricardo Gazzinelli, Michel Rabinovitch, Sara Cherry, Neal Silverman

iScience. 2022 Sep 16; 25(9): 104909. Published online 2022 Aug 13. doi: 10.1016/j.isci.2022.104909

PMCID:: PMC9436752

Abstract Article PDF–3.3M

Select item 86644864.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86644555.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 76065236.

Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells

Beverly V. Robinson, Victor Faundez, Dorothy A. Lerit

Biochem Soc Trans. Author manuscript; available in PMC 2020 Nov 3.

Published in final edited form as: Biochem Soc Trans. 2020 Oct 30; 48(5): 2101–2115. doi: 10.1042/BST20200261

PMCID:: PMC7606523

Abstract Article PDF–1.7M

Select item 69615787.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 66068488.

Rare variants in MYH15 modify amyotrophic lateral sclerosis risk

Hyerim Kim, Junghwa Lim, Han Bao, Bin Jiao, Se Min Canon, Michael P Epstein, Keqin Xu, Jie Jiang, Janani Parameswaran, Yingjie Li, Kenneth H Moberg, John E Landers, Christina Fournier, Emily G Allen, Jonathan D Glass, Thomas S Wingo, Peng Jin

Hum Mol Genet. 2019 Jul 15; 28(14): 2309–2318. Published online 2019 Apr 1. doi: 10.1093/hmg/ddz063

PMCID:: PMC6606848

Abstract Article PDF–27M

Select item 65482279.

Cross-species genetic screens to identify kinase targets for APP reduction in Alzheimer's disease

Claudia H Huichalaf, Ismael Al-Ramahi, Kyung-Won Park, Stacy D Grunke, Nan Lu, Maria de Haro, Karla El-Zein, Tatiana Gallego-Flores, Alma M Perez, Sung Yun Jung, Juan Botas, Huda Y Zoghbi, Joanna L Jankowsky

Hum Mol Genet. 2019 Jun 15; 28(12): 2014–2029. Published online 2019 Feb 12. doi: 10.1093/hmg/ddz034

PMCID:: PMC6548227

Abstract Article PDF–24M

Select item 642956410.

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

Kent Nybakken, Steven A Vokes, Ting-Yi Lin, Andrew P McMahon, Norbert Perrimon

Nat Genet. Author manuscript; available in PMC 2019 Mar 22.

Published in final edited form as: Nat Genet. 2005 Dec; 37(12): 1323–1332. Published online 2005 Nov 20. doi: 10.1038/ng1682

PMCID:: PMC6429564

Abstract Article PDF–1.8M

Select item 593136911.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 582743412.

The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis

Emily A. McMillan, Sheila M. Longo, Michael D. Smith, Sarah Broskin, Baicheng Lin, Nisha K. Singh, Todd I. Strochlic

J Biol Chem. 2018 Feb 23; 293(8): 2990–3002. Published online 2018 Jan 11. doi: 10.1074/jbc.M117.814657

PMCID:: PMC5827434

Abstract Article PDF–2.6M

Select item 570780513.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900214.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 482931715.

Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing

Alborz Mazloomian, Irmtraud M Meyer

RNA Biol. 2015 Dec; 12(12): 1391–1401. Published online 2015 Oct 29. doi: 10.1080/15476286.2015.1107703

PMCID:: PMC4829317

Abstract Article PDF–609K

Select item 478811616.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Abstract Article PDF–4.7M

Select item 473800517.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 470597918.

The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub

Pak N. Kwong, Michael Chambers, Ajay A. Vashisht, Wiam Turki-Judeh, Tak Yu Yau, James A. Wohlschlegel, Albert J. Courey

J Biol Chem. 2015 Dec 11; 290(50): 30119–30130. Published online 2015 Oct 19. doi: 10.1074/jbc.M115.681171

Correction in:: J Biol Chem. 2016 Mar 25; 291(13): 6784.

PMCID:: PMC4705979

Abstract Article PDF–1.3M

Select item 464270919.

Identification of potential drug targets for tuberous sclerosis complex by synthetic screens combining CRISPR-based knockouts with RNAi

Benjamin E. Housden, Alexander J. Valvezan, Colleen Kelley, Richelle Sopko, Yanhui Hu, Charles Roesel, Shuailiang Lin, Michael Buckner, Rong Tao, Bahar Yilmazel, Stephanie E. Mohr, Brendan D. Manning, Norbert Perrimon

Sci Signal. Author manuscript; available in PMC 2016 Mar 8.

Published in final edited form as: Sci Signal. 2015; 8(393): rs9. Published online 2015 Sep 8. doi: 10.1126/scisignal.aab3729

PMCID:: PMC4642709

Abstract Article PDF–959K

Select item 457069720.

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach

Flavio Pazos Obregón, Cecilia Papalardo, Sebastián Castro, Gustavo Guerberoff, Rafael Cantera

BMC Genomics. 2015; 16(1): 694. Published online 2015 Sep 15. doi: 10.1186/s12864-015-1888-3

PMCID:: PMC4570697

Abstract Article PDF–2.0M

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