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Select item 109821171.

LET-767 determines lipid droplet protein targeting and lipid homeostasis

Lin Fu, Jingjing Zhang, Yanli Wang, Huiyin Wu, Xiumei Xu, Chunxia Li, Jirong Li, Jing Liu, Haizhen Wang, Xue Jiang, Zhihao Li, Yaomei He, Pingsheng Liu, Yingjie Wu, Xiaoju Zou, Bin Liang

J Cell Biol. 2024 Jun 3; 223(6): e202311024. Published online 2024 Mar 29. doi: 10.1083/jcb.202311024

PMCID:: PMC10982117

Abstract Article PDF–9.5M

Select item 108351292.

Amino acid and protein specificity of protein fatty acylation in C. elegans

Bingsen Zhang, Yan Yu, Bennett W. Fox, Yinong Liu, Venkatesh P. Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C. Schroeder

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2307515121. Published online 2024 Jan 22. doi: 10.1073/pnas.2307515121

PMCID:: PMC10835129

Abstract Article PDF–1.4M

Select item 107611213.

CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing

Doreen I. Lugano, Lindsey N. Barrett, Dale Chaput, Margaret A. Park, Sandy D. Westerheide

RNA Biol. 2024; 21(1): 1–11. Published online 2023 Dec 21. doi: 10.1080/15476286.2023.2289707

PMCID:: PMC10761121

Abstract Article PDF–2.5M

Select item 103684204.

Lipid homeostasis is essential for a maximal ER stress response

Gilberto Garcia, Hanlin Zhang, Sophia Moreno, C Kimberly Tsui, Brant Michael Webster, Ryo Higuchi-Sanabria, Andrew Dillin

eLife. 2023; 12: e83884. Published online 2023 Jul 25. doi: 10.7554/eLife.83884

PMCID:: PMC10368420

Abstract Article PDF–3.3M

Select item 102799135.

AdipoR2 recruits protein interactors to promote fatty acid elongation and membrane fluidity

Mario Ruiz, Ranjan Devkota, Delaney Kaper, Hanna Ruhanen, Kiran Busayavalasa, Uroš Radović, Marcus Henricsson, Reijo Käkelä, Jan Borén, Marc Pilon

J Biol Chem. 2023 Jun; 299(6): 104799. Published online 2023 May 8. doi: 10.1016/j.jbc.2023.104799

PMCID:: PMC10279913

Abstract Article PDF–4.1M

Select item 101514136.

Isolation and molecular identification of nematode surface mutants with resistance to bacterial pathogens

Delia O’Rourke, Maria J Gravato-Nobre, Dave Stroud, Emily Pritchett, Emily Barker, Rebecca L Price, Sarah A Robinson, Simon Spiro, Patricia Kuwabara, Jonathan Hodgkin

G3 (Bethesda) 2023 May; 13(5): jkad056. Published online 2023 Mar 13. doi: 10.1093/g3journal/jkad056

PMCID:: PMC10151413

Abstract Article PDF–17M

Select item 94378487.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 87531228.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 84626979.

Genes in human obesity loci are causal obesity genes in C. elegans

Wenfan Ke, Jordan N. Reed, Chenyu Yang, Noel Higgason, Leila Rayyan, Carolina Wählby, Anne E. Carpenter, Mete Civelek, Eyleen J. O’Rourke

PLoS Genet. 2021 Sep; 17(9): e1009736. Published online 2021 Sep 7. doi: 10.1371/journal.pgen.1009736

PMCID:: PMC8462697

Abstract Article PDF–4.2M

Select item 844679310.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 833118311.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 826306612.

Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences

Xing Zhang, Benjamin W. Harding, Dina Aggad, Damien Courtine, Jia-Xuan Chen, Nathalie Pujol, Jonathan J. Ewbank

PLoS Genet. 2021 Jun; 17(6): e1009600. Published online 2021 Jun 24. doi: 10.1371/journal.pgen.1009600

PMCID:: PMC8263066

Abstract Article PDF–5.0M

Select item 818482613.

Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

Tomomi Komura, Mikihiro Yamanaka, Kohji Nishimura, Keita Hara, Yoshikazu Nishikawa

NPJ Aging Mech Dis. 2021; 7: 12. Published online 2021 Jun 7. doi: 10.1038/s41514-021-00061-y

PMCID:: PMC8184826

Abstract Article PDF–2.0M

Select item 737784814.

Healthspan pathway maps in C. elegans and humans highlight transcription, proliferation/biosynthesis and lipids

Steffen Möller, Nadine Saul, Alan A. Cohen, Rüdiger Köhling, Sina Sender, Hugo Murua Escobar, Christian Junghanss, Francesca Cirulli, Alessandra Berry, Peter Antal, Priit Adler, Jaak Vilo, Michele Boiani, Ludger Jansen, Dirk Repsilber, Hans Jörgen Grabe, Stephan Struckmann, Israel Barrantes, Mohamed Hamed, Brecht Wouters, Liliane Schoofs, Walter Luyten, Georg Fuellen

Aging (Albany NY) 2020 Jul 15; 12(13): 12534–12581. Published online 2020 Jul 7. doi: 10.18632/aging.103514