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Items: 1 to 20 of 28

1.
Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells
Sara S. Oltra, Sara Colomo, Laura Sin, María Pérez-López, Sara Lázaro, Angela Molina-Crespo, Kyoung-Han Choi, David Ros-Pardo, Lidia Martínez, Saleta Morales, Cristina González-Paramos, Alba Orantes, Mario Soriano, Alberto Hernández, Ana Lluch, Federico Rojo, Joan Albanell, Paulino Gómez-Puertas, Jae-Kyun Ko, David Sarrió, Gema Moreno-Bueno
Cell Death Differ. 2023 May; 30(5): 1366–1381. Published online 2023 Mar 11. doi: 10.1038/s41418-023-01143-y
PMCID:
PMC10154425
AbstractArticlePDF–6.6M
2.
Heterogeneity induced GZMA-F2R communication inefficient impairs antitumor immunotherapy of PD-1 mAb through JAK2/STAT1 signal suppression in hepatocellular carcinoma
Yuxue Gao, Qingguo Xu, Xinqiang Li, Yuan Guo, Bowen Zhang, Yan Jin, Cunle zhu, Yuntai Shen, Pengxiang Yang, Ying Shi, Rifeng Jin, Daojie Liu, Yabo Ouyang, Xiaoni Liu, Wenjing Wang, Dexi Chen, Tongwang Yang
Cell Death Dis. 2022 Mar; 13(3): 213. Published online 2022 Mar 7. doi: 10.1038/s41419-022-04654-7
PMCID:
PMC8901912
AbstractArticlePDF–7.9M
3.
Elevated Extracellular Levels of Granzymes in Patients with Scrub Typhus
Joo-Hee Hwang, Jeong-Hwan Hwang, Chang-Seop Lee
Am J Trop Med Hyg. 2021 Dec; 105(6): 1680–1683. Published online 2021 Oct 11. doi: 10.4269/ajtmh.20-1369
PMCID:
PMC8641366
AbstractArticlePDF–666K
4.
Granzyme A Produced by γ9δ2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity
Valerio Rasi, David C. Wood, Christopher S. Eickhoff, Mei Xia, Nicola Pozzi, Rachel L. Edwards, Michael Walch, Niels Bovenschen, Daniel F. Hoft
Front Immunol. 2021; 12: 712678. Published online 2021 Aug 3. doi: 10.3389/fimmu.2021.712678
PMCID:
PMC8368726
AbstractArticlePDF–1.9M
5.
Pathogenic Ubiquitination of GSDMB Inhibits NK-cell Bactericidal Functions.
Justin M. Hansen, Maarten F. de Jong, Qi Wu, Li-Shu Zhang, David B. Heisler, Laura T. Alto, Neal M. Alto
Cell. Author manuscript; available in PMC 2022 Jun 10.
Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3178–3191.e18. Published online 2021 May 21. doi: 10.1016/j.cell.2021.04.036
PMCID:
PMC8221529
AbstractArticlePDF–2.0M
6.
Lighting a Fire: Can we harness pyroptosis to ignite anti-tumor immunity?
Zhibin Zhang, Ying Zhang, Judy Lieberman
Cancer Immunol Res. Author manuscript; available in PMC 2021 Jul 1.
Published in final edited form as: Cancer Immunol Res. 2021 Jan; 9(1): 2–7. doi: 10.1158/2326-6066.CIR-20-0525
PMCID:
PMC7789047
AbstractArticlePDF–637K
7.
Novel tumour suppressor roles for GZMA and RASGRP1 in Theileria annulata‐transformed macrophages and human B lymphoma cells
Zineb Rchiad, Malak Haidar, Hifzur Rahman Ansari, Shahin Tajeri, Sara Mfarrej, Fathia Ben Rached, Abhinav Kaushik, Gordon Langsley, Arnab Pain
Cell Microbiol. 2020 Dec; 22(12): e13255. Published online 2020 Sep 29. doi: 10.1111/cmi.13255
PMCID:
PMC7685166
AbstractArticlePDF–2.4M
8.
Killer lymphocytes use granulysin, perforin and granzymes to kill intracellular parasites
Farokh Dotiwala, Sachin Mulik, Rafael B Polidoro, James A Ansara, Barbara A Burleigh, Michael Walch, Ricardo T Gazzinelli, Judy Lieberman
Nat Med. Author manuscript; available in PMC 2020 Jun 30.
Published in final edited form as: Nat Med. 2016 Feb; 22(2): 210–216. Published online 2016 Jan 11. doi: 10.1038/nm.4023
PMCID:
PMC7325279
AbstractArticlePDF–1.6M
9.
COVID-19 pneumonia: CD8+ T and NK cells are decreased in number but compensatory increased in cytotoxic potential
Yujie Jiang, Xin Wei, Jingjing Guan, Shuang Qin, Zhongyong Wang, Hong Lu, Jingjing Qian, Lianfeng Wu, Yingxiao Chen, Yanfan Chen, Xiangyang Lin
Clin Immunol. 2020 Sep; 218: 108516. Published online 2020 Jun 20. doi: 10.1016/j.clim.2020.108516
PMCID:
PMC7305921
AbstractArticlePDF–2.1M
10.
Activation of the Granzyme Pathway in Children With Severe Respiratory Syncytial Virus Infection
Reinout A Bem, Albert P Bos, Michael Bots, Angela M Wolbink, S Marieke van Ham, Jan Paul Medema, Rene Lutter, Job B M van Woensel
Pediatr Res. 2008; 63(6): 650–655. doi: 10.1203/PDR.0b013e31816fdc32
PMCID:
PMC7100119
AbstractArticlePDF–563K
11.
Granzyme A in Chikungunya and Other Arboviral Infections
Alessandra S. Schanoski, Thuy T. Le, Dion Kaiserman, Caitlin Rowe, Natalie A. Prow, Diego D. Barboza, Cliomar A. Santos, Paolo M. A. Zanotto, Kelly G. Magalhães, Luigi Aurelio, David Muller, Paul Young, Peishen Zhao, Phillip I. Bird, Andreas Suhrbier
Front Immunol. 2019; 10: 3083. Published online 2020 Jan 14. doi: 10.3389/fimmu.2019.03083
PMCID:
PMC6971054
AbstractArticlePDF–4.1M
12.
Granzyme A in Human Platelets Regulates the Synthesis of Pro-Inflammatory Cytokines by Monocytes in Aging
Robert A. Campbell, Zechariah Franks, Anish Bhatnagar, Jesse W. Rowley, Bhanu K. Manne, Mark A. Supiano, Hansjorg Schwertz, Andrew S. Weyrich, Matthew T. Rondina
J Immunol. Author manuscript; available in PMC 2019 Jan 1.
Published in final edited form as: J Immunol. 2018 Jan 1; 200(1): 295–304. Published online 2017 Nov 22. doi: 10.4049/jimmunol.1700885
PMCID:
PMC5736423
AbstractArticlePDF–1.4M
13.
A real-time PCR signature to discriminate between tuberculosis and other pulmonary diseases
Lucas Laux da Costa, Melaine Delcroix, Elis R. Dalla Costa, Isaías V. Prestes, Mariana Milano, Steve S. Francis, Gisela Unis, Denise R. Silva, Lee W. Riley, Maria L. R. Rossetti
Tuberculosis (Edinb) Author manuscript; available in PMC 2016 Jul 1.
Published in final edited form as: Tuberculosis (Edinb). 2015 Jul; 95(4): 421–425. Published online 2015 May 14. doi: 10.1016/j.tube.2015.04.008
PMCID:
PMC4475479
AbstractArticlePDF–438K
14.
Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease
Sarvari Velaga, Sya N. Ukena, Ulrike Dringenberg, Christina Alter, Julian Pardo, Olivia Kershaw, Anke Franzke
PLoS One. 2015; 10(4): e0124927. Published online 2015 Apr 30. doi: 10.1371/journal.pone.0124927
PMCID:
PMC4415808
AbstractArticlePDF–451K
15.
Identification of Serpinb6b as a Species-specific Mouse Granzyme A Inhibitor Suggests Functional Divergence between Human and Mouse Granzyme A
Dion Kaiserman, Sarah E. Stewart, Kim Plasman, Kris Gevaert, Petra Van Damme, Phillip I. Bird
J Biol Chem. 2014 Mar 28; 289(13): 9408–9417. Published online 2014 Feb 6. doi: 10.1074/jbc.M113.525808
PMCID:
PMC3979379
AbstractArticlePDF–1.8M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
Granzyme A Cleaves a Mitochondrial Complex I Protein to Initiate Caspase-Independent Cell Death
Denis Martinvalet, Derek M. Dykxhoorn, Roger Ferrini, Judy Lieberman
Cell. Author manuscript; available in PMC 2010 Mar 17.
Published in final edited form as: Cell. 2008 May 16; 133(4): 681–692. doi: 10.1016/j.cell.2008.03.032
PMCID:
PMC2840390
AbstractArticlePDF–3.3M
18.
Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis
Jerome Thiery, Dennis Keefe, Saviz Saffarian, Denis Martinvalet, Michael Walch, Emmanuel Boucrot, Tomas Kirchhausen, Judy Lieberman
Blood. 2010 Feb 25; 115(8): 1582–1593. Prepublished online 2009 Dec 28. doi: 10.1182/blood-2009-10-246116
PMCID:
PMC2830763
AbstractArticle
19.
The cytotoxic T lymphocyte protease granzyme A cleaves and inactivates poly(adenosine 5′-diphosphate-ribose) polymerase-1
Pengcheng Zhu, Denis Martinvalet, Dipanjan Chowdhury, Dong Zhang, Ann Schlesinger, Judy Lieberman
Blood. 2009 Aug 6; 114(6): 1205–1216. Prepublished online 2009 Jun 8. doi: 10.1182/blood-2008-12-195768
PMCID:
PMC2723016
AbstractArticle
20.
The major human and mouse granzymes are structurally and functionally divergent
Dion Kaiserman, Catherina H. Bird, Jiuru Sun, Antony Matthews, Kheng Ung, James C. Whisstock, Philip E. Thompson, Joseph A. Trapani, Phillip I. Bird
J Cell Biol. 2006 Nov 20; 175(4): 619–630. doi: 10.1083/jcb.200606073
PMCID:
PMC2064598
AbstractArticlePDF–1.6M

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