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Select item 111531311.

Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Vanessa M. Monteil, Shane C. Wright, Matheus Dyczynski, Max J. Kellner, Sofia Appelberg, Sebastian W. Platzer, Ahmed Ibrahim, Hyesoo Kwon, Ioannis Pittarokoilis, Mattia Mirandola, Georg Michlits, Stephanie Devignot, Elizabeth Elder, Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker M. Lauschke, Cristiano Salata, Nazif Elaldi, Friedemann Weber, Nuria Monserrat, David W. Hawman, Heinz Feldmann, Moritz Horn, Josef M. Penninger, Ali Mirazimi

Nat Microbiol. 2024; 9(6): 1499–1512. Published online 2024 Mar 28. doi: 10.1038/s41564-024-01672-3

PMCID:: PMC11153131

Abstract Article PDF–4.9M

Select item 111480372.

Apolipoprotein O modulates cholesterol metabolism via NRF2/CYB5R3 independent of LDL receptor

Jin Chen, Jiarui Hu, Xin Guo, Yang Yang, Donglu Qin, Xiaoyu Tang, Zhijie Huang, Fengjiao Wang, Die Hu, Daoquan Peng, Bilian Yu

Cell Death Dis. 2024 Jun; 15(6): 389. Published online 2024 Jun 3. doi: 10.1038/s41419-024-06778-4

PMCID:: PMC11148037

Abstract Article PDF–5.5M

Select item 110889853.

Multifaceted roles of Meg3 in cellular senescence and atherosclerosis

Xiao Cheng, Mohamed Sham Shihabudeen Haider Ali, Vijaya Bhaskar Baki, Matthew Moran, Huabo Su, Xinghui Sun

Atherosclerosis. Author manuscript; available in PMC 2024 May 13.

Published in final edited form as: Atherosclerosis. 2024 May; 392: 117506. Published online 2024 Mar 8. doi: 10.1016/j.atherosclerosis.2024.117506

PMCID:: PMC11088985

Abstract Article PDF–3.0M

Select item 110311984.

Trem2 promotes foamy macrophage lipid uptake and survival in atherosclerosis

Michael T. Patterson, Maria M. Firulyova, Yingzheng Xu, Hannah Hillman, Courtney Bishop, Alisha Zhu, Grant H. Hickok, Patricia R. Schrank, Christine E. Ronayne, Zakariya Caillot, Gavin Fredrickson, Ainsley E. Kennedy, Nisha Acharya, Jaap G. Neels, Giulia Chinetti, Xavier Revelo, Ingunn M. Stromnes, Stoyan Ivanov, Tyler D. Bold, Konstantin Zaitsev, Jesse W. Williams

Nat Cardiovasc Res. 2023; 2(11): 1015–1031. Published online 2023 Oct 30. doi: 10.1038/s44161-023-00354-3

PMCID:: PMC11031198

Abstract Article PDF–16M

Select item 110065325.

Deficiency of lncRNA MERRICAL abrogates macrophage chemotaxis and diabetes-associated atherosclerosis

Jingshu Chen, Anurag Jamaiyar, Winona Wu, Yi Hu, Rulin Zhuang, Grasiele Sausen, Henry S. Cheng, Camila de Oliveira Vaz, Daniel Pérez-Cremades, Aspasia Tzani, Michael G. McCoy, Carmel Assa, Samuel Eley, Vinay Randhawa, Kwangwoon Lee, Jorge Plutzky, Naomi M. Hamburg, Marc S. Sabatine, Mark W. Feinberg

Cell Rep. Author manuscript; available in PMC 2024 Apr 10.

Published in final edited form as: Cell Rep. 2024 Mar 26; 43(3): 113815. Published online 2024 Feb 29. doi: 10.1016/j.celrep.2024.113815

PMCID:: PMC11006532

Abstract Article PDF–3.3M

Select item 110047296.

FXR1 is an IL-19 responsive RNA binding protein that destabilizes Pro-inflammatory transcripts in vascular smooth muscle cells

Allison B. Herman, Christine N. Vrakas, Mitali Ray, Sheri E. Kelemen, Michael J. Sweredoski, Annie Moradian, Dale S. Haines, Michael V. Autieri

Cell Rep. Author manuscript; available in PMC 2024 Apr 10.

Published in final edited form as: Cell Rep. 2018 Jul 31; 24(5): 1176–1189. doi: 10.1016/j.celrep.2018.07.002

PMCID:: PMC11004729

Abstract Article PDF–1.9M

Select item 109654797.

Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis

James A. Votava, Steven V. John, Zhonggang Li, Shuyang Chen, Jing Fan, Brian W. Parks

J Lipid Res. 2024 Mar; 65(3): 100525. Published online 2024 Feb 28. doi: 10.1016/j.jlr.2024.100525

PMCID:: PMC10965479

Abstract Article PDF–2.3M

Select item 109530488.

Proteolysis of the low‐density lipoprotein receptor in hepatocytes is mediated by BMP1 but not by other astacin proteases

Katherine A. B. Kellett, Kate Fisher, Harry Aldworth, Nigel M. Hooper

FEBS Lett. 2023 Jun; 597(11): 1489–1502. Published online 2023 Jun 5. doi: 10.1002/1873-3468.14667

PMCID:: PMC10953048

Abstract Article PDF–2.4M

Select item 109176609.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 1086656510.

Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolites

Susana Cavallero, Mehrdad Roustaei, Sandro Satta, Jae Min Cho, Henry Phan, Kyung In Baek, Ana M. Blázquez-Medela, Sheila Gonzalez-Ramos, Khoa Vu, Seul-Ki Park, Tomohiro Yokota, Jennifer Sumner, Julia J. Mack, Curt D. Sigmund, Srinivasa T. Reddy, Rongsong Li, Tzung K. Hsiai

Sci Adv. 2024 Feb 16; 10(7): eadj7481. Published online 2024 Feb 14. doi: 10.1126/sciadv.adj7481

PMCID:: PMC10866565

Abstract Article PDF–3.3M

Select item 1084520711.

Gut ribotoxic stress responses facilitate dyslipidemia via metabolic reprogramming: an environmental health prediction

Juil Kim, Hoyoung Jeong, Navin Ray, Ki-Hyung Kim, Yuseok Moon

Theranostics. 2024; 14(3): 1289–1311. Published online 2024 Jan 20. doi: 10.7150/thno.88586

PMCID:: PMC10845207

Abstract Article PDF–13M

Select item 1065410112.

Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure

Ouzna Dali, Shereen D’Cruz, Louis Legoff, Mariam Diba Lahmidi, Celine Heitz, Pierre-Etienne Merret, Pierre-Yves Kernanec, Farzad Pakdel, Fatima Smagulova

Life Sci Alliance. 2024 Feb; 7(2): e202302237. Published online 2023 Nov 16. doi: 10.26508/lsa.202302237

PMCID:: PMC10654101

Abstract Article PDF–3.1M

Select item 1060936113.

LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8

Ryan M. Allen, Danielle L. Michell, Ashley B. Cavnar, Wanying Zhu, Neil Makhijani, Danielle M. Contreras, Chase A. Raby, Elizabeth M. Semler, Carlisle DeJulius, Mark Castleberry, Youmin Zhang, Marisol Ramirez-Solano, Shilin Zhao, Craig Duvall, Amanda C. Doran, Quanhu Sheng, MacRae F. Linton, Kasey C. Vickers

Nat Cell Biol. Author manuscript; available in PMC 2023 Oct 27.

Published in final edited form as: Nat Cell Biol. 2022 Dec; 24(12): 1701–1713. Published online 2022 Dec 6. doi: 10.1038/s41556-022-01030-7

PMCID:: PMC10609361

Abstract Article PDF–7.4M

Select item 1060524614.

CETP Expression in Bone-Marrow-Derived Cells Reduces the Inflammatory Features of Atherosclerosis in Hypercholesterolemic Mice

Thiago Rentz, Gabriel G. Dorighello, Renata R. dos Santos, Lohanna M. Barreto, Israelle N. Freitas, Carolina M. Lazaro, Daniela S. Razolli, Patricia M. Cazita, Helena C. F. Oliveira

Biomolecules. 2023 Oct; 13(10): 1556. Published online 2023 Oct 22. doi: 10.3390/biom13101556

PMCID:: PMC10605246

Abstract Article PDF–2.0M

Select item 1059864115.

Tanshinone IIA alleviates atherosclerosis in LDLR^−/− mice by regulating efferocytosis of macrophages

Jiarou Wang, Yifan Zhang, Xiaoteng Feng, Min Du, Sijin Li, Xindi Chang, Ping Liu

Front Pharmacol. 2023; 14: 1233709. Published online 2023 Oct 11. doi: 10.3389/fphar.2023.1233709

PMCID:: PMC10598641

Abstract Article PDF–2.9M

Select item 1053203016.

Alkylresorcinols as New Modulators of the Metabolic Activity of the Gut Microbiota

Anastasia A. Zabolotneva, Andrei M. Gaponov, Sergey A. Roumiantsev, Ilya Yu. Vasiliev, Tatiana V. Grigoryeva, Oleg I. Kit, Elena Yu. Zlatnik, Aleksey Yu. Maksimov, Anna S. Goncharova, Inna A. Novikova, Svetlana A. Appolonova, Pavel A. Markin, Aleksandr V. Shestopalov

Int J Mol Sci. 2023 Sep; 24(18): 14206. Published online 2023 Sep 18. doi: 10.3390/ijms241814206

PMCID:: PMC10532030

Abstract Article PDF–2.9M

Select item 1052978617.

Cell-autonomous regulation of complement C3 by factor H limits macrophage efferocytosis and exacerbates atherosclerosis

Máté G. Kiss, Nikolina Papac-Miličević, Florentina Porsch, Dimitrios Tsiantoulas, Tim Hendrikx, Minoru Takaoka, Huy Q. Dinh, Marie-Sophie Narzt, Laura Göderle, Mária Ozsvár-Kozma, Michael Schuster, Nikolaus Fortelny, Anastasiya Hladik, Sylvia Knapp, Florian Gruber, Matthew C. Pickering, Christoph Bock, Filip K. Swirski, Klaus Ley, Alma Zernecke, Clément Cochain, Claudia Kemper, Ziad Mallat, Christoph J. Binder

Immunity. Author manuscript; available in PMC 2024 Aug 8.

Published in final edited form as: Immunity. 2023 Aug 8; 56(8): 1809–1824.e10. Published online 2023 Jul 26. doi: 10.1016/j.immuni.2023.06.026

PMCID:: PMC10529786

Abstract Article PDF–3.4M

Select item 1047447018.

Effect of diet and genotype on the miRNome of mice with altered lipoprotein metabolism

Marco Busnelli, Stefano Manzini, Alice Colombo, Elsa Franchi, Matteo Chiara, Gaia Zaffaroni, David Horner, Giulia Chiesa

iScience. 2023 Sep 15; 26(9): 107615. Published online 2023 Aug 11. doi: 10.1016/j.isci.2023.107615

PMCID:: PMC10474470

Abstract Article PDF–3.3M

Select item 1045341519.

Capillary Dynamics Regulate Post-Ischemic Muscle Damage and Regeneration in Experimental Hindlimb Ischemia

Galina Wirth, Greta Juusola, Santeri Tarvainen, Johanna P. Laakkonen, Petra Korpisalo, Seppo Ylä-Herttuala

Cells. 2023 Aug; 12(16): 2060. Published online 2023 Aug 14. doi: 10.3390/cells12162060

PMCID:: PMC10453415

Abstract Article PDF–2.7M

Select item 1040756420.

Chronic-binge ethanol feeding aggravates systemic dyslipidemia in Ldlr^-/- mice, thereby accelerating hepatic fibrosis

Constanze Hoebinger, Dragana Rajcic, Beatriz Silva, Tim Hendrikx

Front Endocrinol (Lausanne) 2023; 14: 1148827. Published online 2023 Jul 25. doi: 10.3389/fendo.2023.1148827

PMCID:: PMC10407564

Abstract Article PDF–3.8M

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