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Items: 1 to 20 of 350

1.
FLI1 is associated with regulation of DNA methylation and megakaryocytic differentiation in FPDMM caused by a RUNX1 transactivation domain mutation
Yuki Tanaka, Yuri Nakanishi, Erina Furuhata, Ken-ichi Nakada, Rino Maruyama, Harukazu Suzuki, Takahiro Suzuki
Sci Rep. 2024; 14: 14080. Published online 2024 Jun 18. doi: 10.1038/s41598-024-64829-4
PMCID:
PMC11189521
AbstractArticlePDF–3.1M
2.
Central nervous system embryonal tumors with EWSR1-PLAGL1 rearrangements reclassified as INI-1 deficient tumors at relapse
Kevin J. Bielamowicz, Mary Beth Littrell, Gregory W. Albert, Lora S. Parker, Sateesh Jayappa, Kenneth Aldape, Murat Gokden
J Neurooncol. 2024; 168(2): 367–373. Published online 2024 Apr 19. doi: 10.1007/s11060-024-04667-6
PMCID:
PMC11147842
AbstractArticlePDF–1.2M
3.
An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation
Chunlin Wang, Maoting Hu, Kunlin Yu, Wuling Liu, Anling Hu, Yi Kuang, Lei Huang, Babu Gajendran, Eldad Zacksenhaus, Xiao Xiao, Yaacov Ben-David
Mol Med Rep. 2024 Jun; 29(6): 107. Published online 2024 Apr 26. doi: 10.3892/mmr.2024.13231
PMCID:
PMC11082641
AbstractArticlePDF–4.3M
4.
Comprehensive Transcriptomic Analysis of EWSR1::WT1 Targets Identifies CDK4/6 Inhibitors as an Effective Therapy for Desmoplastic Small Round Cell Tumors
Justin W. Magrath, Shruthi Sanjitha Sampath, Dane A. Flinchum, Alifiani B. Hartono, Ilon N. Goldberg, Julia R. Boehling, Suzana D. Savkovic, Sean B. Lee
Cancer Res. 2024 May 2; 84(9): 1426–1442. Published online 2024 Apr 8. doi: 10.1158/0008-5472.CAN-23-3334
PMCID:
PMC11063761
AbstractArticlePDF–24M
5.
Interaction network of human early embryonic transcription factors
Lisa Gawriyski, Zenglai Tan, Xiaonan Liu, Iftekhar Chowdhury, Dicle Malaymar Pinar, Qin Zhang, Jere Weltner, Eeva-Mari Jouhilahti, Gong-Hong Wei, Juha Kere, Markku Varjosalo
EMBO Rep. 2024 Mar; 25(3): 1589–1622. Published online 2024 Jan 31. doi: 10.1038/s44319-024-00074-0
PMCID:
PMC10933267
AbstractArticlePDF–2.9M
6.
FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression
Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu, Yaacov Ben-David
BMC Cancer. 2024; 24: 326. Published online 2024 Mar 9. doi: 10.1186/s12885-024-12075-2
PMCID:
PMC10925000
AbstractArticlePDF–4.6M
7.
Integrated analysis reveals FLI1 regulates the tumor immune microenvironment via its cell-type-specific expression and transcriptional regulation of distinct target genes of immune cells in breast cancer
Jianying Pei, Ying Peng, Kexin Ma, Chunyan Lan, Tingting Zhang, Yan Li, Xiaofang Chen, Huafang Gao
BMC Genomics. 2024; 25: 250. Published online 2024 Mar 6. doi: 10.1186/s12864-024-10174-9
PMCID:
PMC10916124
AbstractArticlePDF–9.8M
8.
The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation
Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett
Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4
PMCID:
PMC10869800
AbstractArticlePDF–9.3M
9.
Identification of Novel/Rare EWSR1 Fusion Partners in Undifferentiated Mesenchymal Neoplasms
Carmen Salguero-Aranda, Elena Di Blasi, Lourdes Galán, Laura Zaldumbide, Gema Civantos, David Marcilla, Enrique de Álava, Juan Díaz-Martín
Int J Mol Sci. 2024 Feb; 25(3): 1735. Published online 2024 Feb 1. doi: 10.3390/ijms25031735
PMCID:
PMC10855420
AbstractArticlePDF–3.8M
10.
FLI-1 is expressed in a wide variety of hematolymphoid neoplasms: a special concern in the differential diagnosis
Uiju Cho, Hee Jeong Cha, Hyun Jung Kim, Soo Kee Min, Hee Kyung Kim, Hye Ra Jung, Gyeongsin Park, Ji Eun Kim
Clin Exp Med. 2024; 24(1): 18. Published online 2024 Jan 27. doi: 10.1007/s10238-023-01284-x
PMCID:
PMC10821826
AbstractArticlePDF–2.3M
11.
Report and literature review of four cases of EWSR1::NFATC2 round cell sarcoma
Lili Liu, Lan Li, Yi Ding, Fangzhou Kong, Wenfa Mo, Hongtao Ye, Danhua Shen
Diagn Pathol. 2024; 19: 19. Published online 2024 Jan 22. doi: 10.1186/s13000-024-01443-y
PMCID:
PMC10801936
AbstractArticlePDF–2.3M
12.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
13.
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions
Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav D. Diwan, Zunamys I. Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Dominic Helm, Martin Schneider, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert B. Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl
Nat Commun. 2024; 15: 51. Published online 2024 Jan 2. doi: 10.1038/s41467-023-44360-2
PMCID:
PMC10761971
AbstractArticlePDF–3.4M
14.
EWSR1 (Ewing Sarcoma Breakpoint Region 1) maintains centromere identity
Risa Kitagawa, Yohei Niikura, Argentina Becker, Peter J Houghton, Katsumi Kitagawa
Cell Rep. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112568. Published online 2023 May 25. doi: 10.1016/j.celrep.2023.112568
PMCID:
PMC10758295
AbstractArticlePDF–2.8M
15.
A complex with poly(A)-binding protein and EWS facilitates the transcriptional function of oncogenic ETS transcription factors in prostate cells
Benjamin M. Greulich, Saranya Rajendran, Nicholas F. Downing, Taylor R. Nicholas, Peter C. Hollenhorst
J Biol Chem. 2023 Dec; 299(12): 105453. Published online 2023 Nov 11. doi: 10.1016/j.jbc.2023.105453
PMCID:
PMC10704431
AbstractArticlePDF–1.3M
16.
EWS/FLI1 Characterization, Activation, Repression, Target Genes and Therapeutic Opportunities in Ewing Sarcoma
Muhammad Yasir, Jinyoung Park, Wanjoo Chun
Int J Mol Sci. 2023 Oct; 24(20): 15173. Published online 2023 Oct 14. doi: 10.3390/ijms242015173
PMCID:
PMC10607184
AbstractArticlePDF–1.7M
17.
Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates
Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert
Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644
PMCID:
PMC10565876
AbstractArticlePDF–3.7M
18.
Role of the transcription factor Fli-1 on the CXCL10/CXCR3 Axis*
Xuan Wang, Mara Lennard Richard, Tomika S. Caldwell, Kamala Sundararaj, Shuzo Sato, Tamara K. Nowling, Xian K. Zhang
Front Immunol. 2023; 14: 1219279. Published online 2023 Sep 15. doi: 10.3389/fimmu.2023.1219279
PMCID:
PMC10543418
AbstractArticlePDF–1.4M
19.
Friend leukemia integration 1 overexpression decreases endometrial receptivity and induces embryo implantation failure by promoting PART1 transcription in the endometrial epithelial cells
Yile Zhang, Beining Yin, Sichen Li, Yueyue Cui, Jianrong Liu
PeerJ. 2023; 11: e16105. Published online 2023 Sep 26. doi: 10.7717/peerj.16105
PMCID:
PMC10540769
AbstractArticlePDF–10M
20.
PTP4A2 promotes lysophagy by dephosphorylation of VCP/p97 at Tyr805
Yunpeng Bai, Guimei Yu, Hong-Ming Zhou, Ovini Amarasinghe, Yuan Zhou, Peipei Zhu, Qinglin Li, Lujuan Zhang, Frederick Nguele Meke, Yiming Miao, Eli Chapman, W. Andy Tao, Zhong-Yin Zhang
Autophagy. 2023; 19(5): 1562–1581. Published online 2022 Nov 7. doi: 10.1080/15548627.2022.2140558
PMCID:
PMC10240998
AbstractArticlePDF–4.4M

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