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Items: 1 to 20 of 30

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
Maya Junghans, Felix John, Hilal Cihankaya, Daniel Schliebs, Konstanze F. Winklhofer, Verian Bader, Johann Matschke, Carsten Theiss, Veronika Matschke
Front Cell Neurosci. 2022; 16: 963169. Published online 2022 Aug 31. doi: 10.3389/fncel.2022.963169
PMCID:
PMC9470831
AbstractArticlePDF–4.6M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant wobbler mice, a model of motor neuron degeneration
Constance S. Petit, Jane J. Lee, Sebastian Boland, Sharan Swarup, Romain Christiano, Zon Weng Lai, Niklas Mejhert, Shane D. Elliott, David McFall, Sara Haque, Eric J. Huang, Roderick T. Bronson, J. Wade Harper, Robert V. Farese, Jr, Tobias C. Walther
Proc Natl Acad Sci U S A. 2020 May 12; 117(19): 10565–10574. Published online 2020 Apr 28. doi: 10.1073/pnas.1913956117
PMCID:
PMC7229683
AbstractArticlePDF–1.7M
7.
Tumor Necrosis Factor α Induces a Metalloprotease-Disintegrin, ADAM8 (CD 156): Implications for Neuron–Glia Interactions during Neurodegeneration
Uwe Schlomann, Silvia Rathke-Hartlieb, Shunsuke Yamamoto, Harald Jockusch, Jörg W. Bartsch
J Neurosci. 2000 Nov 1; 20(21): 7964–7971. doi: 10.1523/JNEUROSCI.20-21-07964.2000
PMCID:
PMC6772711
AbstractArticlePDF–7.3M
8.
Tumor Necrosis Factor-α (TNF-α) Regulates Shedding of TNF-α Receptor 1 by the Metalloprotease-Disintegrin ADAM8: Evidence for a Protease-Regulated Feedback Loop in Neuroprotection
Jörg W. Bartsch, Dirk Wildeboer, Garrit Koller, Silvia Naus, Andrea Rittger, Marcia L. Moss, Yuji Minai, Harald Jockusch
J Neurosci. 2010 Sep 8; 30(36): 12210–12218. doi: 10.1523/JNEUROSCI.1520-10.2010
PMCID:
PMC6633558
AbstractArticlePDF–2.0M
9.
Bcl-2 Sensitivity Differentiates Two Pathways for Motoneuronal Death in the wobbler Mutant Mouse
Muriel Coulpier, Marie-Pierre Junier, Marc Peschanski, Patrick A. Dreyfus
J Neurosci. 1996 Oct 1; 16(19): 5897–5904. doi: 10.1523/JNEUROSCI.16-19-05897.1996
PMCID:
PMC6579179
AbstractArticlePDF–1.5M
10.
Transforming growth factor alpha (TGF alpha) expression in degenerating motoneurons of the murine mutant wobbler: a neuronal signal for astrogliosis?
MP Junier, M Coulpier, N Le Forestier, J Cadusseau, F Suzuki, M Peschanski, PA Dreyfus
J Neurosci. 1994 Jul 1; 14(7): 4206–4216. doi: 10.1523/JNEUROSCI.14-07-04206.1994
PMCID:
PMC6577032
AbstractPDF–2.4M
11.
EARP, a multisubunit tethering complex involved in endocytic recycling
Christina Schindler, Yu Chen, Jing Pu, Xiaoli Guo, Juan S. Bonifacino
Nat Cell Biol. Author manuscript; available in PMC 2015 Nov 1.
Published in final edited form as: Nat Cell Biol. 2015 May; 17(5): 639–650. Published online 2015 Mar 23. doi: 10.1038/ncb3129
PMCID:
PMC4417048
AbstractArticlePDF–2.9M
12.
The Wobbler Mouse Model of Amyotrophic Lateral Sclerosis (ALS) Displays Hippocampal Hyperexcitability, and Reduced Number of Interneurons, but No Presynaptic Vesicle Release Impairments
Karina D. Thielsen, Jakob M. Moser, Thomas Schmitt-John, Morten S. Jensen, Kimmo Jensen, Mai Marie Holm
PLoS One. 2013; 8(12): e82767. Published online 2013 Dec 11. doi: 10.1371/journal.pone.0082767
Correction in:
PLoS One. 2015; 10(3): e0121772.
PMCID:
PMC3859636
AbstractArticlePDF–1.6M
13.
Loss of Vps54 Function Leads to Vesicle Traffic Impairment, Protein Mis-Sorting and Embryonic Lethality
Páll Karlsson, Aida Droce, Jakob M. Moser, Simon Cuhlmann, Carolina Ortiz Padilla, Peter Heimann, Jörg W. Bartsch, Annette Füchtbauer, Ernst-Martin Füchtbauer, Thomas Schmitt-John
Int J Mol Sci. 2013 Jun; 14(6): 10908–10925. Published online 2013 May 24. doi: 10.3390/ijms140610908
PMCID:
PMC3709709
AbstractArticlePDF–1.6M
14.
The wobbler mouse, an ALS animal model
Jakob Maximilian Moser, Paolo Bigini, Thomas Schmitt-John
Mol Genet Genomics. 2013; 288(5): 207–229. Published online 2013 Mar 29. doi: 10.1007/s00438-013-0741-0
PMCID:
PMC3664746
AbstractArticlePDF–656K
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex
F. Javier Pérez-Victoria, Guillermo Abascal-Palacios, Igor Tascón, Andrey Kajava, Javier G. Magadán, Erik P. Pioro, Juan S. Bonifacino, Aitor Hierro
Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29): 12860–12865. Published online 2010 Jul 6. doi: 10.1073/pnas.1004756107
PMCID:
PMC2919957
AbstractArticlePDF–1.8M
17.
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells
Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin
Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108
PMCID:
PMC2556270
AbstractArticlePDF–493K
18.
Motor neuron cell death in wobbler mutant mice follows overexpression of the G-protein-coupled, protease-activated receptor for thrombin.
B. W. Festoff, M. R. D'Andrea, B. A. Citron, R. M. Salcedo, I. V. Smirnova, P. Andrade-Gordon
Mol Med. 2000 May; 6(5): 410–429.
PMCID:
PMC1949954
SummaryPDF–285K
19.
Animal model of human disease: Werdnig-Hoffmann disease (infantile spinal muscular atrophy).
J. E. Leestma
Am J Pathol. 1980 Sep; 100(3): 821–824.
PMCID:
PMC1903565
SummaryPage BrowsePDF–1022K
20.
Neuron volume in the ventral horn in Wobbler mouse motoneuron disease: a light microscope stereological study
P. DOCKERY, Y. TANG, M. MORAIS, L. L. VACCA-GALLOWAY
J Anat. 1997 Jul; 191(Pt 1): 89–98. doi: 10.1046/j.1469-7580.1997.19110089.x
Correction in:
J Anat, volume 106 on page 255
PMCID:
PMC1467662
SummaryPDF–372K

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