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Select item 82980991.

Specific KIF1A–adaptor interactions control selective cargo recognition

Jessica J.A. Hummel, Casper C. Hoogenraad

J Cell Biol. 2021 Oct 4; 220(10): e202105011. Published online 2021 Jul 21. doi: 10.1083/jcb.202105011

PMCID:: PMC8298099

Abstract Article PDF–7.1M

Select item 79393862.

A kinetic dissection of the fast and superprocessive kinesin-3 KIF1A reveals a predominant one-head-bound state during its chemomechanical cycle

Taylor M. Zaniewski, Allison M. Gicking, John Fricks, William O. Hancock

J Biol Chem. 2020 Dec 25; 295(52): 17889–17903. Published online 2021 Jan 13. doi: 10.1074/jbc.RA120.014961

PMCID:: PMC7939386

Abstract Article PDF–9.1M

Select item 78444213.

Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms

Breane G. Budaitis, Shashank Jariwala, Lu Rao, Yang Yue, David Sept, Kristen J. Verhey, Arne Gennerich

J Cell Biol. 2021 Apr 5; 220(4): e202004227. Published online 2021 Jan 26. doi: 10.1083/jcb.202004227

PMCID:: PMC7844421

Abstract Article PDF–9.1M

Select item 63426474.

Kinesin-3 responds to local microtubule dynamics to target synaptic cargo delivery to the presynapse

Pedro Guedes-Dias, Jeffrey J. Nirschl, Nohely C. Abreu, Mariko K. Tokito, Carsten Janke, Maria M. Magiera, Erika L.F. Holzbaur

Curr Biol. Author manuscript; available in PMC 2020 Jan 21.

Published in final edited form as: Curr Biol. 2019 Jan 21; 29(2): 268–282.e8. Published online 2019 Jan 3. doi: 10.1016/j.cub.2018.11.065

PMCID:: PMC6342647

Abstract Article PDF–1.7M

Select item 60772475.

Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca²⁺/CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites

Riccardo Stucchi, Gabriela Plucińska, Jessica J.A. Hummel, Eitan E. Zahavi, Irune Guerra San Juan, Oleg Klykov, Richard A. Scheltema, A.F. Maarten Altelaar, Casper C. Hoogenraad

Cell Rep. 2018 Jul 17; 24(3): 685–700. Published online 2018 Jul 17. doi: 10.1016/j.celrep.2018.06.071

PMCID:: PMC6077247

Abstract Article

Select item 57146126.

Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4

Vinita Bharat, Michael Siebrecht, Katja Burk, Saheeb Ahmed, Carsten Reissner, Mahdokht Kohansal-Nodehi, Vicky Steubler, Markus Zweckstetter, Jonathan T. Ting, Camin Dean

Cell Rep. 2017 Nov 21; 21(8): 2118–2133. Published online 2017 Nov 21. doi: 10.1016/j.celrep.2017.10.084

PMCID:: PMC5714612

Abstract Article

Select item 53751317.

Targeted high throughput sequencing in hereditary ataxia and spastic paraplegia

Zafar Iqbal, Siri L. Rydning, Iselin M. Wedding, Jeanette Koht, Lasse Pihlstrøm, Aina H. Rengmark, Sandra P. Henriksen, Chantal M. E. Tallaksen, Mathias Toft

PLoS One. 2017; 12(3): e0174667. Published online 2017 Mar 31. doi: 10.1371/journal.pone.0174667

Correction in:: PLoS One. 2017; 12(10): e0186571.

PMCID:: PMC5375131

Abstract Article PDF–1.9M

Select item 47413058.

Microtubule‐binding protein doublecortin‐like kinase 1 (DCLK1) guides kinesin‐3‐mediated cargo transport to dendrites

Joanna Lipka, Lukas C Kapitein, Jacek Jaworski, Casper C Hoogenraad

EMBO J. 2016 Feb 1; 35(3): 302–318. Published online 2016 Jan 12. doi: 10.15252/embj.201592929

PMCID:: PMC4741305

Abstract Article PDF–5.0M

Select item 37541399.

Glycoproteins gE and gI Are Required for Efficient KIF1A-Dependent Anterograde Axonal Transport of Alphaherpesvirus Particles in Neurons

Radomir Kratchmarov, Tal Kramer, Todd M. Greco, Matthew P. Taylor, Toh Hean Ch'ng, Ileana M. Cristea, Lynn W. Enquist

J Virol. 2013 Sep; 87(17): 9431–9440. doi: 10.1128/JVI.01317-13

PMCID:: PMC3754139

Abstract Article PDF–1.4M

Select item 368043510.

Diabetes Alters KIF1A and KIF5B Motor Proteins in the Hippocampus

Filipa I. Baptista, Maria J. Pinto, Filipe Elvas, Ramiro D. Almeida, António F. Ambrósio

PLoS One. 2013; 8(6): e65515. Published online 2013 Jun 12. doi: 10.1371/journal.pone.0065515

PMCID:: PMC3680435

Abstract Article PDF–4.7M

Select item 360254111.

Role of Us9 Phosphorylation in Axonal Sorting and Anterograde Transport of Pseudorabies Virus

Radomir Kratchmarov, Matthew P. Taylor, Lynn W. Enquist

PLoS One. 2013; 8(3): e58776. Published online 2013 Mar 19. doi: 10.1371/journal.pone.0058776

PMCID:: PMC3602541

Abstract Article PDF–1.1M

Select item 352783812.

Kinesin-3 mediates axonal sorting and directional transport of alphaherpesvirus particles in neurons

Tal Kramer, Todd M. Greco, Matthew P. Taylor, Anthony E. Ambrosini, Ileana M. Cristea, Lynn W. Enquist

Cell Host Microbe. Author manuscript; available in PMC 2013 Dec 13.

Published in final edited form as: Cell Host Microbe. 2012 Dec 13; 12(6): 806–814. doi: 10.1016/j.chom.2012.10.013

PMCID:: PMC3527838

Abstract Article PDF–2.4M

Select item 335525813.

KIF1A missense mutations in SPG30, an autosomal recessive spastic paraplegia: distinct phenotypes according to the nature of the mutations

Stephan Klebe, Alexander Lossos, Hamid Azzedine, Emeline Mundwiller, Ruth Sheffer, Marion Gaussen, Cecilia Marelli, Magdalena Nawara, Wassila Carpentier, Vincent Meyer, Agnès Rastetter, Elodie Martin, Delphine Bouteiller, Laurent Orlando, Gabor Gyapay, Khalid H El-Hachimi, Batel Zimmerman, Moriya Gamliel, Adel Misk, Israela Lerer, Alexis Brice, Alexandra Durr, Giovanni Stevanin

Eur J Hum Genet. 2012 Jun; 20(6): 645–649. Published online 2012 Jan 18. doi: 10.1038/ejhg.2011.261

PMCID:: PMC3355258

Abstract Article PDF–341K

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315515915.

KIF1A, an Axonal Transporter of Synaptic Vesicles, Is Mutated in Hereditary Sensory and Autonomic Neuropathy Type 2

Jean-Baptiste Rivière, Siriram Ramalingam, Valérie Lavastre, Masoud Shekarabi, Sébastien Holbert, Julie Lafontaine, Myriam Srour, Nancy Merner, Daniel Rochefort, Pascale Hince, Rébecca Gaudet, Anne-Marie Mes-Masson, Jonathan Baets, Henry Houlden, Bernard Brais, Garth A. Nicholson, Hilde Van Esch, Shahriar Nafissi, Peter De Jonghe, Mary M. Reilly, Vincent Timmerman, Patrick A. Dion, Guy A. Rouleau

Am J Hum Genet. 2011 Aug 12; 89(2): 219–230. doi: 10.1016/j.ajhg.2011.06.013

PMCID:: PMC3155159

Abstract Article PDF–943K

Select item 308308216.

Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis

Yaniv Erlich, Simon Edvardson, Emily Hodges, Shamir Zenvirt, Pramod Thekkat, Avraham Shaag, Talya Dor, Gregory J. Hannon, Orly Elpeleg

Genome Res. 2011 May; 21(5): 658–664. doi: 10.1101/gr.117143.110

PMCID:: PMC3083082

Abstract Article PDF–308K

Select item 305920717.

An Unconventional Kinesin and Cytoplasmic Dynein Are Responsible for Interkinetic Nuclear Migration in Neural Stem Cells

Jin-Wu Tsai, Wei-Nan Lian, Shahrnaz Kemal, Arnold Kriegstein, Richard B. Vallee

Nat Neurosci. Author manuscript; available in PMC 2011 Jun 1.

Published in final edited form as: Nat Neurosci. 2010 Dec; 13(12): 1463–1471. Published online 2010 Oct 31. doi: 10.1038/nn.2665

PMCID:: PMC3059207

Abstract Article PDF–1.2M

Select item 269391718.

Dynamic Changes in Presynaptic and Axonal Transport Proteins Combined with Striatal Neuroinflammation Precede Dopaminergic Neuronal Loss in a Rat Model of AAV α-Synucleinopathy

Chee Yeun Chung, James B. Koprich, Hasan Siddiqi, Ole Isacson

J Neurosci. 2009 Mar 18; 29(11): 3365–3373. doi: 10.1523/JNEUROSCI.5427-08.2009

PMCID:: PMC2693917

Abstract Article PDF–681K

Select item 266196419.

Mammalian Kinesin-3 Motors Are Dimeric In Vivo and Move by Processive Motility upon Release of Autoinhibition

Jennetta W Hammond, Dawen Cai, T. Lynne Blasius, Zhe Li, Yuyang Jiang, Gloria T Jih, Edgar Meyhofer, Kristen J Verhey

PLoS Biol. 2009 Mar; 7(3): e1000072. Published online 2009 Mar 31. doi: 10.1371/journal.pbio.1000072

PMCID:: PMC2661964

Abstract Article PDF–1.3M

Select item 180201020.

Loss of α-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function

Koji Ikegami, Robb L. Heier, Midori Taruishi, Hiroshi Takagi, Masahiro Mukai, Shuichi Shimma, Shu Taira, Ken Hatanaka, Nobuhiro Morone, Ikuko Yao, Patrick K. Campbell, Shigeki Yuasa, Carsten Janke, Grant R. MacGregor, Mitsutoshi Setou

Proc Natl Acad Sci U S A. 2007 Feb 27; 104(9): 3213–3218. Published online 2007 Feb 20. doi: 10.1073/pnas.0611547104

PMCID:: PMC1802010

Abstract Article PDF–1.9M

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