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Select item 109078251.

CYP1B1 affects the integrity of the blood–brain barrier and oxidative stress in the striatum: An investigation of manganese‐induced neurotoxicity

Juan Wu, Yueran Li, Shuwei Tian, Shufang Na, Hongyan Wei, Yafei Wu, Yafei Yang, Zixia Shen, Jiayue Ding, Shenglan Bao, Siqi Liu, Lingyun Li, Rongling Feng, Yong Zhu, Chunyan He, Jiang Yue

CNS Neurosci Ther. 2024 Mar; 30(3): e14633. Published online 2024 Mar 1. doi: 10.1111/cns.14633

PMCID:: PMC10907825

Abstract Article PDF–12M

Select item 107066152.

AhR and CYP1B1 Control Oxygen Effects on Bone Marrow Progenitor Cells: The Enrichment of Multiple Olfactory Receptors as Potential Microbiome Sensors

Michele C. Larsen, Catherine M. Rondelli, Ahmed Almeldin, Yong-Seok Song, Alhaji N’Jai, David L. Alexander, E. Camilla Forsberg, Nader Sheibani, Colin R. Jefcoate

Int J Mol Sci. 2023 Dec; 24(23): 16884. Published online 2023 Nov 28. doi: 10.3390/ijms242316884

PMCID:: PMC10706615

Abstract Article PDF–6.9M

Select item 104742883.

ALKBH5 facilitates CYP1B1 mRNA degradation via m6A demethylation to alleviate MSC senescence and osteoarthritis progression

Guiwen Ye, Jinteng Li, Wenhui Yu, Zhongyu Xie, Guan Zheng, Wenjie Liu, Shan Wang, Qian Cao, Jiajie Lin, Zepeng Su, Dateng Li, Yunshu Che, Shuai Fan, Peng Wang, Yanfeng Wu, Huiyong Shen

Exp Mol Med. 2023 Aug; 55(8): 1743–1756. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01059-0

PMCID:: PMC10474288

Abstract Article PDF–6.7M

Select item 102719364.

Loss of cytochrome P450 (CYP)1B1 mitigates hyperoxia response in adult mouse lung by reprogramming metabolism and translation

Sandra L. Grimm, Rachel E. Stading, Matthew J. Robertson, Tanmay Gandhi, Chenlian Fu, Weiwu Jiang, Guobin Xia, Krithika Lingappan, Cristian Coarfa, Bhagavatula Moorthy

Redox Biol. 2023 Aug; 64: 102790. Published online 2023 Jun 16. doi: 10.1016/j.redox.2023.102790

PMCID:: PMC10271936

Abstract Article PDF–9.1M

Select item 99168355.

Cytochrome P450 1B1 Expression Regulates Intracellular Iron Levels and Oxidative Stress in the Retinal Endothelium

Yong-Seok Song, Ismail S. Zaitoun, Shoujian Wang, Soesiawati R. Darjatmoko, Christine M. Sorenson, Nader Sheibani

Int J Mol Sci. 2023 Feb; 24(3): 2420. Published online 2023 Jan 26. doi: 10.3390/ijms24032420

PMCID:: PMC9916835

Abstract Article PDF–5.4M

Select item 92072686.

Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation

Francesca Alessandrini, Renske de Jong, Maria Wimmer, Ann-Marie Maier, Isis Fernandez, Miriam Hils, Jeroen T. Buters, Tilo Biedermann, Ulrich M. Zissler, Christian Hoffmann, Julia Esser-von-Bieren, Carsten B. Schmidt-Weber, Caspar Ohnmacht

Front Immunol. 2022; 13: 901194. Published online 2022 Jun 6. doi: 10.3389/fimmu.2022.901194

PMCID:: PMC9207268

Abstract Article PDF–6.0M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 79732148.

Absence of Cytochrome P450-1b1 Increases Susceptibility of Pressure-Induced Axonopathy in the Murine Retinal Projection

Naseem Amirmokhtari, Brian D. Foresi, Shiv S. Dewan, Rachida A. Bouhenni, Matthew A. Smith

Front Cell Dev Biol. 2021; 9: 636321. Published online 2021 Mar 5. doi: 10.3389/fcell.2021.636321

PMCID:: PMC7973214

Abstract Article PDF–2.7M

Select item 71822359.

Retinal astrocytes transcriptome reveals Cyp1b1 regulates the expression of genes involved in cell adhesion and migration

Juliana Falero-Perez, Christine M. Sorenson, Nader Sheibani

PLoS One. 2020; 15(4): e0231752. Published online 2020 Apr 24. doi: 10.1371/journal.pone.0231752

PMCID:: PMC7182235

Abstract Article PDF–1.7M

Select item 712080710.

Targeted deletion of Cyp1b1 in pericytes results in attenuation of retinal neovascularization and trabecular meshwork dysgenesis

Juliana Falero-Perez, Michele C. Larsen, Leandro B. C. Teixeira, Hao F. Zhang, Volkhard Lindner, Christine M. Sorenson, Colin R. Jefcoate, Nader Sheibani

Trends Dev Biol. Author manuscript; available in PMC 2020 Apr 3.

Published in final edited form as: Trends Dev Biol. 2019; 12: 1–12.

PMCID:: PMC7120807

Abstract Article PDF–1.1M

Select item 700435311.

Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development

Meghan Maguire, Michele Campaigne Larsen, Chad M. Vezina, Loredana Quadro, Youn-Kyung Kim, Sherry A. Tanumihardjo, Colin R. Jefcoate

PLoS One. 2020; 15(2): e0228436. Published online 2020 Feb 6. doi: 10.1371/journal.pone.0228436

PMCID:: PMC7004353

Abstract Article PDF–3.2M

Select item 696685612.

6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice

Ajeeth K. Pingili, Brett L. Jennings, Kamalika Mukherjee, Wadah Akroush, Frank J. Gonzalez, Kafait U. Malik

Biol Sex Differ. 2020; 11: 4. Published online 2020 Jan 16. doi: 10.1186/s13293-019-0280-4

PMCID:: PMC6966856

Abstract Article PDF–3.8M

Select item 695535013.

Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected

Cailing Liu, Taiga Miyajima, Geetha Melangath, Takashi Miyai, Shivakumar Vasanth, Neha Deshpande, Varun Kumar, Stephan Ong Tone, Reena Gupta, Shan Zhu, Dijana Vojnovic, Yuming Chen, Eleanor G. Rogan, Bodhiswatta Mondal, Muhammad Zahid, Ula V. Jurkunas

Proc Natl Acad Sci U S A. 2020 Jan 7; 117(1): 573–583. Published online 2019 Dec 18. doi: 10.1073/pnas.1912546116

PMCID:: PMC6955350

Abstract Article PDF–2.5M

Select item 662924014.

Tie2 regulates endocardial sprouting and myocardial trabeculation

Xianghu Qu, Cristina Harmelink, H. Scott Baldwin

JCI Insight. 2019 Jul 11; 4(13): e96002. Published online 2019 Jul 11. doi: 10.1172/jci.insight.96002

PMCID:: PMC6629240

Abstract Article PDF–60M

Select item 662057915.

Cyp1b1-deficient retinal astrocytes are more proliferative and migratory and are protected from oxidative stress and inflammation

Juliana Falero-Perez, Christine M. Sorenson, Nader Sheibani

Am J Physiol Cell Physiol. 2019 Jun 1; 316(6): C767–C781. Published online 2019 Mar 20. doi: 10.1152/ajpcell.00021.2019

PMCID:: PMC6620579

Abstract Article

Select item 660240716.

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma

Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe

Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050

PMCID:: PMC6602407

Abstract Article PDF–3.5M

Select item 658120417.

Obesity alters oestrogen metabolism and contributes to pulmonary arterial hypertension

Kirsty M. Mair, Katie Y. Harvey, Alasdair D. Henry, Dianne Z. Hillyard, Margaret Nilsen, Margaret R. MacLean

Eur Respir J. 2019 Jun; 53(6): 1801524. Published online 2019 Jun 13. doi: 10.1183/13993003.01524-2018

PMCID:: PMC6581204

Abstract Article PDF–1.3M

Select item 635149918.

A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis

Matthew R. Jones, Salma Dilai, Arun Lingampally, Cho-Ming Chao, Soula Danopoulos, Gianni Carraro, Regina Mukhametshina, Jochen Wilhelm, Eveline Baumgart-Vogt, Denise Al Alam, Chengshui Chen, Parviz Minoo, Jin San Zhang, Saverio Bellusci

Front Genet. 2018; 9: 746. Published online 2019 Jan 23. doi: 10.3389/fgene.2018.00746

PMCID:: PMC6351499

Abstract Article PDF–5.6M

Select item 630306819.

Polycyclic aromatic hydrocarbons (PAHs) present in ambient urban dust drive proinflammatory T cell and dendritic cell responses via the aryl hydrocarbon receptor (AHR) in vitro

Chelsea A. O’Driscoll, Madeline E. Gallo, Erica J. Hoffmann, John H. Fechner, James J. Schauer, Christopher A. Bradfield, Joshua D. Mezrich

PLoS One. 2018; 13(12): e0209690. Published online 2018 Dec 21. doi: 10.1371/journal.pone.0209690

PMCID:: PMC6303068

Abstract Article PDF–1.7M

Select item 629804020.

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman

Cell. Author manuscript; available in PMC 2019 Dec 13.

Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025

Correction in:: Cell. 2019 Jul 11; 178(2): 507–508.

PMCID:: PMC6298040

Abstract Article PDF–1.2M

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