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Select item 114370851.

piRNAs are regulators of metabolic reprogramming in stem cells

Patricia Rojas-Ríos, Aymeric Chartier, Camille Enjolras, Julie Cremaschi, Céline Garret, Adel Boughlita, Anne Ramat, Martine Simonelig

Nat Commun. 2024; 15: 8405. Published online 2024 Sep 27. doi: 10.1038/s41467-024-52709-4

PMCID:: PMC11437085

Abstract Article PDF–7.2M

Select item 113546132.

Activation of the 5-HT1A Receptor by Eltoprazine Restores Mitochondrial and Motor Deficits in a Drosophila Model of Fragile X Syndrome

Anna Vannelli, Vittoria Mariano, Claudia Bagni, Alexandros K. Kanellopoulos

Int J Mol Sci. 2024 Aug; 25(16): 8787. Published online 2024 Aug 13. doi: 10.3390/ijms25168787

PMCID:: PMC11354613

Abstract Article PDF–2.3M

Select item 111447303.

Xbp1 targets canonical UPR^ER and non-canonical pathways in separate tissues to promote longevity

Mengjia Li, Haocheng Shou, Guillermo Martínez Corrales, Tatiana Svermova, Alessandra Vieira Franco, Nazif Alic

iScience. 2024 Jun 21; 27(6): 109962. Published online 2024 May 11. doi: 10.1016/j.isci.2024.109962

PMCID:: PMC11144730

Abstract Article PDF–3.9M

Select item 111254074.

Curcumin-mediated alleviation of dextran-induced leaky gut in Drosophila melanogaster

Mufliha Khaerani, Rizkya Chaeratunnisa, Annisa Salsabila, Asbah Asbah, Rangga M. Asri, Akiko Shiratsuchi, Firzan Nainu

Narra J. 2024 Apr; 4(1): e743. Published online 2024 Apr 22. doi: 10.52225/narra.v4i1.743

PMCID:: PMC11125407

Abstract Article PDF–704K

Select item 111132685.

Restricting bioenergetic efficiency enhances longevity and mitochondrial redox capacity in Drosophila melanogaster

Analisa L. Taylor, Olga Dubuisson, Pritika Pandey, Elizabeth R. M. Zunica, Bolormaa Vandanmagsar, Wagner S. Dantas, Alyssa Johnson, Christopher L. Axelrod, John P. Kirwan

Aging Cell. 2024 May; 23(5): e14107. Published online 2024 Feb 11. doi: 10.1111/acel.14107

PMCID:: PMC11113268

Abstract Article PDF–655K

Select item 110983226.

Muscle Psn gene combined with exercise contribute to healthy aging of skeletal muscle and lifespan by adaptively regulating Sirt1/PGC-1α and arm pathway

Ying-hui Gao, Deng-tai Wen, Zhong-rui Du, Jing-feng Wang, Shi-jie Wang

PLoS One. 2024; 19(5): e0300787. Published online 2024 May 16. doi: 10.1371/journal.pone.0300787

PMCID:: PMC11098322

Abstract Article PDF–2.6M

Select item 110904947.

PGC-1α integrates insulin signaling with mitochondrial physiology and behavior in a Drosophila model of Fragile X Syndrome

Eliana D. Weisz, Adam R. Fenton, Thomas A. Jongens

NPJ Metab Health Dis. Author manuscript; available in PMC 2024 May 13.

Published in final edited form as: NPJ Metab Health Dis. 2024; 2: 2. Published online 2024 Feb 21. doi: 10.1038/s44324-024-00004-7

PMCID:: PMC11090494

Abstract Article PDF–1.8M

Select item 109425768.

Delta-dependent Notch activation closes the early neuroblast temporal program to promote lineage progression and neurogenesis termination in Drosophila

Chhavi Sood, Md Ausrafuggaman Nahid, Kendall R Branham, Matt Pahl, Susan E Doyle, Sarah E Siegrist

eLife. 2024; 12: RP88565. Published online 2024 Feb 23. doi: 10.7554/eLife.88565

PMCID:: PMC10942576

Abstract Article PDF–7.0M

Select item 106634709.

A distinct Acyl-CoA binding protein (ACBP6) shapes tissue plasticity during nutrient adaptation in Drosophila

Xiaotong Li, Jason Karpac

Nat Commun. 2023; 14: 7599. Published online 2023 Nov 21. doi: 10.1038/s41467-023-43362-4

PMCID:: PMC10663470

Abstract Article PDF–6.8M

Select item 1065111010.

KDM5-mediated activation of genes required for mitochondrial biology is necessary for viability in Drosophila

Michael F. Rogers, Owen J. Marshall, Julie Secombe

Development. 2023 Nov 1; 150(21): dev202024. Published online 2023 Nov 6. doi: 10.1242/dev.202024

PMCID:: PMC10651110

Abstract Article

Select item 1064892611.

Octopamine Rescues Endurance and Climbing Speed in Drosophila Clk^out Mutants with Circadian Rhythm Disruption

Maryam Safdar, Robert J. Wessells

Cells. 2023 Nov; 12(21): 2515. Published online 2023 Oct 25. doi: 10.3390/cells12212515

PMCID:: PMC10648926

Abstract Article PDF–2.7M

Select item 1052345112.

Iditarod, a Drosophila homolog of the Irisin precursor FNDC5, is critical for exercise performance and cardiac autophagy

Tyler Cobb, Irene Hwang, Michael Soukar, Sim Namkoong, Uhn-Soo Cho, Maryam Safdar, Myungjin Kim, Robert J. Wessells, Jun Hee Lee

Proc Natl Acad Sci U S A. 2023 Sep 26; 120(39): e2220556120. Published online 2023 Sep 18. doi: 10.1073/pnas.2220556120

PMCID:: PMC10523451

Abstract Article PDF–3.1M

Select item 1046831213.

New mutant alleles for Spargel/dPGC-1 highlights the function of Spargel RRM domain in oogenesis and expands the role of Spargel in embryogenesis and intracellular transport

Swagota D Roy, Sabarish Nagarajan, Md Shah Jalal, Md Abul Basar, Atanu Duttaroy

G3 (Bethesda) 2023 Sep; 13(9): jkad142. Published online 2023 Jun 27. doi: 10.1093/g3journal/jkad142

PMCID:: PMC10468312

Abstract Article PDF–1.0M

Select item 1026415714.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 1006474315.

Role of muscle FOXO gene in exercise against the skeletal muscle and cardiac age-related defects and mortality caused by high-salt intake in Drosophila

Deng-tai Wen, Ying-hui Gao, Jingfeng Wang, Shijie Wang, Qi Zhong, Wen-qi Hou

Genes Nutr. 2023; 18: 6. Published online 2023 Mar 30. doi: 10.1186/s12263-023-00725-2

PMCID:: PMC10064743

Abstract Article PDF–11M

Select item 986008316.

Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs

Tommy H. Taslim, Abdiasis M. Hussein, Riya Keshri, Julien R. Ishibashi, Tung C. Chan, Bich N. Nguyen, Shuozhi Liu, Daniel Brewer, Stuart Harper, Scott Lyons, Ben Garver, Jimmy Dang, Nanditaa Balachandar, Samriddhi Jhajharia, Debra del Castillo, Julie Mathieu, Hannele Ruohola-Baker

Stem Cell Reports. 2023 Jan 10; 18(1): 269–288. Published online 2022 Dec 8. doi: 10.1016/j.stemcr.2022.11.004