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Select item 105797981.

The AMPK-like protein kinases Sik2 and Sik3 interact with Hipk and induce synergistic tumorigenesis in a Drosophila cancer model

Kewei Yu, Niveditha Ramkumar, Kenneth Kin Lam Wong, Gritta Tettweiler, Esther M. Verheyen

Front Cell Dev Biol. 2023; 11: 1214539. Published online 2023 Oct 3. doi: 10.3389/fcell.2023.1214539

PMCID:: PMC10579798

Abstract Article PDF–4.5M

Select item 104697592.

A phosphorylation-deficient mutant of Sik3, a homolog of Sleepy, alters circadian sleep regulation by PDF neurons in Drosophila

Riho Kobayashi, Shin Nakane, Jun Tomita, Hiromasa Funato, Masashi Yanagisawa, Kazuhiko Kume

Front Neurosci. 2023; 17: 1181555. Published online 2023 Aug 17. doi: 10.3389/fnins.2023.1181555

PMCID:: PMC10469759

Abstract Article PDF–5.5M

Select item 98701063.

SIK3 and Wnk converge on Fray to regulate glial K⁺ buffering and seizure susceptibility

Lorenzo Lones, Aaron DiAntonio

PLoS Genet. 2023 Jan; 19(1): e1010581. Published online 2023 Jan 10. doi: 10.1371/journal.pgen.1010581

PMCID:: PMC9870106

Abstract Article PDF–2.5M

Select item 97134314.

Transcriptome analysis of FOXO-dependent hypoxia gene expression identifies Hipk as a regulator of low oxygen tolerance in Drosophila

Kate Ding, Elizabeth C Barretto, Michael Johnston, Byoungchun Lee, Marco Gallo, Savraj S Grewal

G3 (Bethesda) 2022 Dec; 12(12): jkac263. Published online 2022 Oct 6. doi: 10.1093/g3journal/jkac263

PMCID:: PMC9713431

Abstract Article PDF–1.0M

Select item 92522835.

LKB1 is physiologically required for sleep from Drosophila melanogaster to the Mus musculus

Ziyi Liu, Lifen Jiang, Chaoyi Li, Chengang Li, Jingqun Yang, Jianjun Yu, Renbo Mao, Yi Rao

Genetics. 2022 Jul; 221(3): iyac082. Published online 2022 May 17. doi: 10.1093/genetics/iyac082

Correction in:: Genetics. 2022 Nov; 222(3): iyac149.

PMCID:: PMC9252283

Abstract Article PDF–785K

Select item 87245776.

Origin and Development of the Adipose Tissue, a Key Organ in Physiology and Disease

Esmeralda Parra-Peralbo, Ana Talamillo, Rosa Barrio

Front Cell Dev Biol. 2021; 9: 786129. Published online 2021 Dec 21. doi: 10.3389/fcell.2021.786129

PMCID:: PMC8724577

Abstract Article PDF–1.5M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 86644558.

Functional requirements of protein kinases and phosphatases in the development of the Drosophila melanogaster wing

Cristina M Ostalé, Nuria Esteban, Ana López-Varea, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab348. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab348

PMCID:: PMC8664455

Abstract Article PDF–2.9M

Select item 84456029.

Activation of IRE1, PERK and salt-inducible kinases leads to Sec body formation in Drosophila S2 cells

Chujun Zhang, Wessel van Leeuwen, Marloes Blotenburg, Angelica Aguilera-Gomez, Sem Brussee, Rianne Grond, Harm H. Kampinga, Catherine Rabouille

J Cell Sci. 2021 Sep 1; 134(17): jcs258685. Published online 2021 Sep 6. doi: 10.1242/jcs.258685

PMCID:: PMC8445602

Abstract Article

Select item 827796910.

Metabolic reprogramming in cancer: mechanistic insights from Drosophila

Kenneth Kin Lam Wong, Esther M. Verheyen

Dis Model Mech. 2021 Jul 1; 14(7): dmm048934. Published online 2021 Jul 9. doi: 10.1242/dmm.048934

PMCID:: PMC8277969

Abstract Article

Select item 818958211.

What fuels the fly: Energy metabolism in Drosophila and its application to the study of obesity and diabetes

Nirmalya Chatterjee, Norbert Perrimon

Sci Adv. 2021 Jun; 7(24): eabg4336. Published online 2021 Jun 9. doi: 10.1126/sciadv.abg4336

PMCID:: PMC8189582

Abstract Article PDF–327K

Select item 794642112.

Bidirectional regulation of glial potassium buffering – glioprotection versus neuroprotection

Hailun Li, Lorenzo Lones, Aaron DiAntonio

eLife. 2021; 10: e62606. Published online 2021 Mar 1. doi: 10.7554/eLife.62606

PMCID:: PMC7946421

Abstract Article PDF–3.0M

Select item 775863213.

Postsynaptic cAMP signalling regulates the antagonistic balance of Drosophila glutamate receptor subtypes

Kai Zhao, Huilin Hong, Lu Zhao, Sheng Huang, Ying Gao, Elsayed Metwally, Yuqiang Jiang, Stephan J. Sigrist, Yong Q. Zhang

Development. 2020 Dec 1; 147(24): dev191874. Published online 2020 Dec 16. doi: 10.1242/dev.191874

PMCID:: PMC7758632

Abstract Article

Select item 729519714.

Salt inducible kinases as novel Notch interactors in the developing Drosophila retina

H. Bahar Şahin, Sercan Sayın, Maxine Holder, Kuyaş Buğra, Arzu Çelik

PLoS One. 2020; 15(6): e0234744. Published online 2020 Jun 15. doi: 10.1371/journal.pone.0234744

PMCID:: PMC7295197

Abstract Article PDF–3.5M

Select item 704806915.

Regulation of growth in Drosophila melanogaster: the roles of mitochondrial metabolism

Howard T Jacobs, Jack George, Esko Kemppainen

J Biochem. 2020 Mar; 167(3): 267–277. Published online 2020 Jan 11. doi: 10.1093/jb/mvaa002

PMCID:: PMC7048069

Abstract Article PDF–369K

Select item 697440416.

Forward genetic approach for behavioral neuroscience using animal models

Hiromasa FUNATO

Proc Jpn Acad Ser B Phys Biol Sci. 2020 Jan 10; 96(1): 10–31. doi: 10.2183/pjab.96.002

PMCID:: PMC6974404

Abstract Article PDF–1.4M

Select item 689109417.

SIK3 suppresses neuronal hyperexcitability by regulating the glial capacity to buffer K⁺ and water

Hailun Li, Alexandra Russo, Aaron DiAntonio

J Cell Biol. 2019 Dec 2; 218(12): 4017–4029. Published online 2019 Oct 23. doi: 10.1083/jcb.201907138

PMCID:: PMC6891094

Abstract Article PDF–2.0M

Select item 607622518.

Forward genetic analysis of sleep in randomly mutagenized mice

Hiromasa Funato, Chika Miyoshi, Tomoyuki Fujiyama, Takeshi Kanda, Makito Sato, Zhiqiang Wang, Jing Ma, Shin Nakane, Jun Tomita, Aya Ikkyu, Miyo Kakizaki, Noriko Hotta, Satomi Kanno, Haruna Komiya, Fuyuki Asano, Takato Honda, Staci J. Kim, Kanako Harano, Hiroki Muramoto, Toshiya Yonezawa, Seiya Mizuno, Shinichi Miyazaki, Linzi Connor, Vivek Kumar, Ikuo Miura, Tomohiro Suzuki, Atsushi Watanabe, Manabu Abe, Fumihiro Sugiyama, Satoru Takahashi, Kenji Sakimura, Yu Hayashi, Qinghua Liu, Kazuhiko Kume, Shigeharu Wakana, Joseph S Takahashi, Masashi Yanagisawa

Nature. Author manuscript; available in PMC 2018 Aug 4.

Published in final edited form as: Nature. 2016 Nov 17; 539(7629): 378–383. Published online 2016 Nov 2. doi: 10.1038/nature20142

PMCID:: PMC6076225

Abstract Article PDF–4.4M

Select item 593136919.

A Whole Animal Platform to Advance A Clinical Kinase Inhibitor Into New Disease Space

Masahiro Sonoshita, Alex P. Scopton, Peter M-U. Ung, Matthew A. Murray, Lisa Silber, Andres Y. Maldonado, Alexander Real, Avner Schlessinger, Ross L. Cagan, Arvin C. Dar

Nat Chem Biol. Author manuscript; available in PMC 2018 Jul 22.

Published in final edited form as: Nat Chem Biol. 2018 Mar; 14(3): 291–298. Published online 2018 Jan 22. doi: 10.1038/nchembio.2556

PMCID:: PMC5931369

Abstract Article PDF–2.9M

Select item 584585220.

The Neurobiological Basis of Sleep: Insights from Drosophila

Sarah Ly, Allan I. Pack, Nirinjini Naidoo

Neurosci Biobehav Rev. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Neurosci Biobehav Rev. 2018 Apr; 87: 67–86. Published online 2018 Jan 31. doi: 10.1016/j.neubiorev.2018.01.015

PMCID:: PMC5845852

Abstract Article PDF–534K

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