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Select item 86644861.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 69615782.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 67509263.

Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis

Jia Zhou, Lingna Xu, Xiuying Duan, Wei Liu, Xiaocui Zhao, Xi Wang, Weina Shang, Xuefei Fang, Huan Yang, Lijun Jia, Jian Bai, Jiayao Zhao, Liquan Wang, Chao Tong

Sci Adv. 2019 Sep; 5(9): eaax0365. Published online 2019 Sep 18. doi: 10.1126/sciadv.aax0365

PMCID:: PMC6750926

Abstract Article PDF–14M

Select item 66217314.

Loss of PAFAH1B2 Reduces Amyloid-β Generation by Promoting the Degradation of Amyloid Precursor Protein C-Terminal Fragments

Richard M. Page, Anna Münch, Thomas Horn, Peer-Hendrik Kuhn, Alessio Colombo, Orly Reiner, Michael Boutros, Harald Steiner, Stefan F. Lichtenthaler, Christian Haass

J Neurosci. 2012 Dec 12; 32(50): 18204–18214. doi: 10.1523/JNEUROSCI.2681-12.2012

PMCID:: PMC6621731

Abstract Article PDF–2.0M

Select item 66202785.

Precursor RNA processing 3 is required for male fertility, and germline stem cell self-renewal and differentiation via regulating spliceosome function in Drosophila testes

Xia Chen, Xiaojin Luan, Qianwen Zheng, Chen Qiao, Wanyin Chen, Min Wang, Yidan Yan, Bing Xie, Cong Shen, Zeyu He, Jun Zhang, Mingxi Liu, Xing Hu, Hong Li, Bo Zheng, Jie Fang, Jun Yu

Sci Rep. 2019; 9: 9988. Published online 2019 Jul 10. doi: 10.1038/s41598-019-46419-x

PMCID:: PMC6620278

Abstract Article PDF–2.0M

Select item 64295646.

A genome-wide RNA interference screen in Drosophila melanogaster cells for new components of the Hh signaling pathway

Kent Nybakken, Steven A Vokes, Ting-Yi Lin, Andrew P McMahon, Norbert Perrimon

Nat Genet. Author manuscript; available in PMC 2019 Mar 22.

Published in final edited form as: Nat Genet. 2005 Dec; 37(12): 1323–1332. Published online 2005 Nov 20. doi: 10.1038/ng1682

PMCID:: PMC6429564

Abstract Article PDF–1.8M

Select item 62813717.

Spliceosome factors target timeless (tim) mRNA to control clock protein accumulation and circadian behavior in Drosophila

Iryna Shakhmantsir, Soumyashant Nayak, Gregory R Grant, Amita Sehgal

eLife. 2018; 7: e39821. Published online 2018 Dec 5. doi: 10.7554/eLife.39821

PMCID:: PMC6281371

Abstract Article PDF–4.1M

Select item 57286868.

The output of protein-coding genes shifts to circular RNAs when the pre-mRNA processing machinery is limiting

Dongming Liang, Deirdre C. Tatomer, Zheng Luo, Huang Wu, Li Yang, Ling-Ling Chen, Sara Cherry, Jeremy E. Wilusz

Mol Cell. Author manuscript; available in PMC 2018 Dec 7.

Published in final edited form as: Mol Cell. 2017 Dec 7; 68(5): 940–954.e3. Published online 2017 Nov 22. doi: 10.1016/j.molcel.2017.10.034

PMCID:: PMC5728686

Abstract Article PDF–3.1M

Select item 57078059.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900210.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 503306111.

An integrative analysis of the InR/PI3K/Akt network identifies the dynamic response to Insulin signaling

Arunachalam Vinayagam, Meghana M. Kulkarni, Richelle Sopko, Xiaoyun Sun, Yanhui Hu, Ankita Nand, Christians Villalta, Ahmadali Moghimi, Xuemei Yang, Stephanie E. Mohr, Pengyu Hong, John Asara, Norbert Perrimon

Cell Rep. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 3062–3074. doi: 10.1016/j.celrep.2016.08.029

PMCID:: PMC5033061

Abstract Article PDF–3.3M

Select item 473800512.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 470597913.

The Central Region of the Drosophila Co-repressor Groucho as a Regulatory Hub

Pak N. Kwong, Michael Chambers, Ajay A. Vashisht, Wiam Turki-Judeh, Tak Yu Yau, James A. Wohlschlegel, Albert J. Courey

J Biol Chem. 2015 Dec 11; 290(50): 30119–30130. Published online 2015 Oct 19. doi: 10.1074/jbc.M115.681171

Correction in:: J Biol Chem. 2016 Mar 25; 291(13): 6784.

PMCID:: PMC4705979

Abstract Article PDF–1.3M

Select item 457717814.

spenito is required for sex determination in Drosophila melanogaster

Dong Yan, Norbert Perrimon

Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37): 11606–11611. Published online 2015 Aug 31. doi: 10.1073/pnas.1515891112

PMCID:: PMC4577178

Abstract Article PDF–1.9M

Select item 452833015.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832916.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 445871417.

The Drosophila Helicase Maleless (MLE) is Implicated in Functions Distinct From its Role in Dosage Compensation

Simona Cugusi, Satish Kallappagoudar, Huiping Ling, John C. Lucchesi

Mol Cell Proteomics. 2015 Jun; 14(6): 1478–1488. Published online 2015 Mar 16. doi: 10.1074/mcp.M114.040667

PMCID:: PMC4458714

Abstract Article PDF–625K

Select item 435288718.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 434448819.

Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED

Tarik Hadžić, Dongkook Park, Katharine C. Abruzzi, Lin Yang, Jennifer S. Trigg, Remo Rohs, Michael Rosbash, Paul H. Taghert

Nucleic Acids Res. 2015 Feb 27; 43(4): 2199–2215. Published online 2015 Jan 29. doi: 10.1093/nar/gku1377

PMCID:: PMC4344488

Abstract Article PDF–5.1M

Select item 427152720.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

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