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Select item 95651571.

CGG repeat expansion in NOTCH2NLC causes mitochondrial dysfunction and progressive neurodegeneration in Drosophila model

Jiaxi Yu, Tongling Liufu, Yilei Zheng, Jin Xu, Lingchao Meng, Wei Zhang, Yun Yuan, Daojun Hong, Nicolas Charlet-Berguerand, Zhaoxia Wang, Jianwen Deng

Proc Natl Acad Sci U S A. 2022 Oct 11; 119(41): e2208649119. Published online 2022 Oct 3. doi: 10.1073/pnas.2208649119

PMCID:: PMC9565157

Abstract Article PDF–3.1M

Select item 84688272.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 80507743.

Stable Isotope Labeling of Amino Acids in Flies (SILAF) Reveals Differential Phosphorylation of Mitochondrial Proteins Upon Loss of OXPHOS Subunits

Florian A. Schober, Ilian Atanassov, David Moore, Javier Calvo-Garrido, Marco F. Moedas, Anna Wedell, Christoph Freyer, Anna Wredenberg

Mol Cell Proteomics. 2021; 20: 100065. Published online 2021 Feb 25. doi: 10.1016/j.mcpro.2021.100065

PMCID:: PMC8050774

Abstract Article PDF–1.8M

Select item 68904654.

Drosophila PSI controls circadian period and the phase of circadian behavior under temperature cycle via tim splicing

Lauren E Foley, Jinli Ling, Radhika Joshi, Naveh Evantal, Sebastian Kadener, Patrick Emery

eLife. 2019; 8: e50063. Published online 2019 Nov 8. doi: 10.7554/eLife.50063

PMCID:: PMC6890465

Abstract Article PDF–3.0M

Select item 67794125.

Accurate genome-wide predictions of spatio-temporal gene expression during embryonic development

Jian Zhou, Ignacio E. Schor, Victoria Yao, Chandra L. Theesfeld, Raquel Marco-Ferreres, Alicja Tadych, Eileen E. M. Furlong, Olga G. Troyanskaya

PLoS Genet. 2019 Sep; 15(9): e1008382. Published online 2019 Sep 25. doi: 10.1371/journal.pgen.1008382

PMCID:: PMC6779412

Abstract Article PDF–5.9M

Select item 66687906.

Defects of mitochondrial RNA turnover lead to the accumulation of double-stranded RNA in vivo

Aleksandra Pajak, Isabelle Laine, Paula Clemente, Najla El-Fissi, Florian A. Schober, Camilla Maffezzini, Javier Calvo-Garrido, Rolf Wibom, Roberta Filograna, Ashish Dhir, Anna Wedell, Christoph Freyer, Anna Wredenberg

PLoS Genet. 2019 Jul; 15(7): e1008240. Published online 2019 Jul 31. doi: 10.1371/journal.pgen.1008240

PMCID:: PMC6668790

Abstract Article PDF–2.6M

Select item 57078057.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890028.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 55595209.

Drosophila protease ClpXP specifically degrades DmLRPPRC1 controlling mitochondrial mRNA and translation

Yuichi Matsushima, Yuta Hirofuji, Masamune Aihara, Song Yue, Takeshi Uchiumi, Laurie S. Kaguni, Dongchon Kang

Sci Rep. 2017; 7: 8315. Published online 2017 Aug 16. doi: 10.1038/s41598-017-08088-6

PMCID:: PMC5559520

Abstract Article PDF–2.6M

Select item 534099810.

A Luciferase-fragment Complementation Assay to Detect Lipid Droplet-associated Protein-Protein Interactions

Petra Kolkhof, Michael Werthebach, Anna van de Venn, Gereon Poschmann, Lili Chen, Michael Welte, Kai Stühler, Mathias Beller

Mol Cell Proteomics. 2017 Mar; 16(3): 329–345. Published online 2016 Dec 12. doi: 10.1074/mcp.M116.061499

PMCID:: PMC5340998

Abstract Article PDF–3.8M

Select item 507911111.

C9orf72 dipeptide repeats impair the assembly, dynamics and function of membrane-less organelles

Kyung-Ha Lee, Peipei Zhang, Hong Joo Kim, Diana Mitrea, Mohona Sarkar, Brian Freibaum, Jaclyn Cika, Maura Coughlin, James Messing, Amandine Molliex, Brian Maxwell, Nam Chul Kim, Jamshid Temirov, Jennifer Moore, Regina-Maria Kolaitis, Timothy Shaw, Bing Bai, Junmin Peng, Richard Kriwacki, J. Paul Taylor

Cell. Author manuscript; available in PMC 2017 Oct 20.

Published in final edited form as: Cell. 2016 Oct 20; 167(3): 774–788.e17. doi: 10.1016/j.cell.2016.10.002

PMCID:: PMC5079111

Abstract Article PDF–2.3M

Select item 503306112.

An integrative analysis of the InR/PI3K/Akt network identifies the dynamic response to Insulin signaling

Arunachalam Vinayagam, Meghana M. Kulkarni, Richelle Sopko, Xiaoyun Sun, Yanhui Hu, Ankita Nand, Christians Villalta, Ahmadali Moghimi, Xuemei Yang, Stephanie E. Mohr, Pengyu Hong, John Asara, Norbert Perrimon

Cell Rep. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 3062–3074. doi: 10.1016/j.celrep.2016.08.029

PMCID:: PMC5033061

Abstract Article PDF–3.3M

Select item 497891913.

Phenotypes Associated with Second Chromosome P Element Insertions in Drosophila melanogaster

Lily Kahsai, Gillian H. Millburn, Kevin R. Cook

G3 (Bethesda) 2016 Aug; 6(8): 2665–2670. Published online 2016 Jun 10. doi: 10.1534/g3.116.030940

PMCID:: PMC4978919

Abstract Article PDF–613K

Select item 488965814.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 480554515.

A genome-wide resource for the analysis of protein localisation in Drosophila

Mihail Sarov, Christiane Barz, Helena Jambor, Marco Y Hein, Christopher Schmied, Dana Suchold, Bettina Stender, Stephan Janosch, Vinay Vikas KJ, RT Krishnan, Aishwarya Krishnamoorthy, Irene RS Ferreira, Radoslaw K Ejsmont, Katja Finkl, Susanne Hasse, Philipp Kämpfer, Nicole Plewka, Elisabeth Vinis, Siegfried Schloissnig, Elisabeth Knust, Volker Hartenstein, Matthias Mann, Mani Ramaswami, K VijayRaghavan, Pavel Tomancak, Frank Schnorrer

eLife. 2016; 5: e12068. Published online 2016 Feb 20. doi: 10.7554/eLife.12068

PMCID:: PMC4805545

Abstract Article PDF–9.1M

Select item 478811616.

Hedgehog Signaling Strength Is Orchestrated by the mir-310 Cluster of MicroRNAs in Response to Diet

Ibrahim Ömer Çiçek, Samir Karaca, Marko Brankatschk, Suzanne Eaton, Henning Urlaub, Halyna R. Shcherbata

Genetics. 2016 Mar; 202(3): 1167–1183. Published online 2016 Jan 22. doi: 10.1534/genetics.115.185371

PMCID:: PMC4788116

Abstract Article PDF–4.7M

Select item 473831117.

A Cross-Species Study of PI3K Protein-Protein Interactions Reveals the Direct Interaction of P85 and SHP2

Susanne B. Breitkopf, Xuemei Yang, Michael J. Begley, Meghana Kulkarni, Yu-Hsin Chiu, Alexa B. Turke, Jessica Lauriol, Min Yuan, Jie Qi, Jeffrey A. Engelman, Pengyu Hong, Maria I. Kontaridis, Lewis C. Cantley, Norbert Perrimon, John M. Asara

Sci Rep. 2016; 6: 20471. Published online 2016 Feb 3. doi: 10.1038/srep20471

PMCID:: PMC4738311

Abstract Article PDF–1.8M

Select item 473800518.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 466317719.

RNA Sequences Required for the Noncoding Function of oskar RNA also Mediate Regulation of Oskar Protein Expression by Bicoid Stability Factor

Young Hee Ryu, Paul M. Macdonald

Dev Biol. Author manuscript; available in PMC 2016 Nov 15.

Published in final edited form as: Dev Biol. 2015 Nov 15; 407(2): 211–223. Published online 2015 Oct 9. doi: 10.1016/j.ydbio.2015.09.014

PMCID:: PMC4663177

Abstract Article PDF–1.0M

Select item 459299620.

SUMO-Enriched Proteome for Drosophila Innate Immune Response

Mithila Handu, Bhagyashree Kaduskar, Ramya Ravindranathan, Amarendranath Soory, Ritika Giri, Vijay Barathi Elango, Harsha Gowda, Girish S. Ratnaparkhi

G3 (Bethesda) 2015 Oct; 5(10): 2137–2154. Published online 2015 Aug 18. doi: 10.1534/g3.115.020958

PMCID:: PMC4592996

Abstract Article PDF–2.0M

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