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Select item 111999551.

Modeling neurodegenerative and neurodevelopmental disorders in the Drosophila mushroom body

Aaron Stahl, Seth M. Tomchik

Learn Mem. 2024 May; 31(5): a053816. Published online 2024 May. doi: 10.1101/lm.053816.123

PMCID:: PMC11199955

Abstract Article PDF–937K

Select item 110631602.

Large-language models facilitate discovery of the molecular signatures regulating sleep and activity

Di Peng, Liubin Zheng, Dan Liu, Cheng Han, Xin Wang, Yan Yang, Li Song, Miaoying Zhao, Yanfeng Wei, Jiayi Li, Xiaoxue Ye, Yuxiang Wei, Zihao Feng, Xinhe Huang, Miaomiao Chen, Yujie Gou, Yu Xue, Luoying Zhang

Nat Commun. 2024; 15: 3685. Published online 2024 May 1. doi: 10.1038/s41467-024-48005-w

PMCID:: PMC11063160

Abstract Article PDF–2.7M

Select item 110489323.

Drosophila Contributions towards Understanding Neurofibromatosis 1

Kalliopi Atsoniou, Eleni Giannopoulou, Eirini-Maria Georganta, Efthimios M. C. Skoulakis

Cells. 2024 Apr; 13(8): 721. Published online 2024 Apr 21. doi: 10.3390/cells13080721

PMCID:: PMC11048932

Abstract Article PDF–2.1M

Select item 110485134.

Non-Mammalian Models for Understanding Neurological Defects in RASopathies

Mario Rodríguez-Martín, Juan Báez-Flores, Vanessa Ribes, María Isidoro-García, Jesus Lacal, Pablo Prieto-Matos

Biomedicines. 2024 Apr; 12(4): 841. Published online 2024 Apr 10. doi: 10.3390/biomedicines12040841

PMCID:: PMC11048513

Abstract Article PDF–1.3M

Select item 107639695.

Neurofibromin 1 mediates sleep depth in Drosophila

Elizabeth B. Brown, Jiwei Zhang, Evan Lloyd, Elizabeth Lanzon, Valentina Botero, Seth Tomchik, Alex C. Keene

PLoS Genet. 2023 Dec; 19(12): e1011049. Published online 2023 Dec 13. doi: 10.1371/journal.pgen.1011049

PMCID:: PMC10763969

Abstract Article PDF–3.0M

Select item 104280716.

Neurofibromin 1 regulates early developmental sleep in Drosophila

Jaclyn Durkin, Amy R. Poe, Samuel J. Belfer, Anyara Rodriguez, Si Hao Tang, James A. Walker, Matthew S. Kayser

Neurobiol Sleep Circadian Rhythms. 2023 Nov; 15: 100101. Published online 2023 Aug 9. doi: 10.1016/j.nbscr.2023.100101

PMCID:: PMC10428071

Abstract Article PDF–8.8M

Select item 102729017.

Humanization for neurological disease modeling: A roadmap to increase the potential of Drosophila model systems

Vladimir L. Katanaev

Animal Model Exp Med. 2023 Jun; 6(3): 230–236. Published online 2023 May 8. doi: 10.1002/ame2.12322

PMCID:: PMC10272901

Abstract Article PDF–877K

Select item 101986058.

A Targeted, Low-Throughput Compound Screen in a Drosophila Model of Neurofibromatosis Type 1 Identifies Simvastatin and BMS-204352 as Potential Therapies for Autism Spectrum Disorder (ASD)

Alex Dyson, Megan Ryan, Shruti Garg, D. Gareth Evans, Richard A. Baines

eNeuro. 2023 May; 10(5): ENEURO.0461-22.2023. Prepublished online 2023 Apr 26. Published online 2023 May 15. doi: 10.1523/ENEURO.0461-22.2023

PMCID:: PMC10198605

Abstract Article PDF–2.0M

Select item 97943809.

Loss of NF1 in Drosophila Larvae Causes Tactile Hypersensitivity and Impaired Synaptic Transmission at the Neuromuscular Junction

Alex Dyson, Megan Ryan, Shruti Garg, D. Gareth Evans, Richard A. Baines

J Neurosci. 2022 Dec 14; 42(50): 9450–9472. doi: 10.1523/JNEUROSCI.0562-22.2022

PMCID:: PMC9794380

Abstract Article PDF–5.5M

Select item 966833410.

Genetic architecture of natural variation of cardiac performance from flies to humans

Saswati Saha, Lionel Spinelli, Jaime A Castro Mondragon, Anaïs Kervadec, Michaela Lynott, Laurent Kremmer, Laurence Roder, Sallouha Krifa, Magali Torres, Christine Brun, Georg Vogler, Rolf Bodmer, Alexandre R Colas, Karen Ocorr, Laurent Perrin

eLife. 2022; 11: e82459. Published online 2022 Nov 16. doi: 10.7554/eLife.82459

PMCID:: PMC9668334

Abstract Article PDF–4.8M

Select item 963564011.

Drosophila FMRP controls miR-276-mediated regulation of nejire mRNA for space-filling dendrite development

Hui Li, Elizabeth R Gavis

G3 (Bethesda) 2022 Nov; 12(11): jkac239. Published online 2022 Sep 14. doi: 10.1093/g3journal/jkac239

PMCID:: PMC9635640

Abstract Article PDF–1.0M

Select item 906492912.

Synaptic Dysfunction Connects Autism Spectrum Disorder and Sleep Disturbances: A Perspective from Studies in Model Organisms

Fusun Doldur-Balli, Toshihiro Imamura, Olivia J. Veatch, Naihua N. Gong, Diane C. Lim, Michael P. Hart, Ted Abel, Matthew S. Kayser, Edward S. Brodkin, Allan I. Pack

Sleep Med Rev. Author manuscript; available in PMC 2023 Apr 1.

Published in final edited form as: Sleep Med Rev. 2022 Apr; 62: 101595. Published online 2022 Jan 25. doi: 10.1016/j.smrv.2022.101595

PMCID:: PMC9064929

Abstract Article PDF–582K

Select item 877312413.

The Use of Drosophila to Understand Psychostimulant Responses

Travis James Philyaw, Adrian Rothenfluh, Iris Titos

Biomedicines. 2022 Jan; 10(1): 119. Published online 2022 Jan 6. doi: 10.3390/biomedicines10010119

PMCID:: PMC8773124

Abstract Article PDF–2.2M

Select item 866983414.

Tumor–host interactions through the lens of Drosophila

David Bilder, Katy Ong, Tsai-Ching Hsi, Kavya Adiga, Jung Kim

Nat Rev Cancer. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Rev Cancer. 2021 Nov; 21(11): 687–700. Published online 2021 Aug 13. doi: 10.1038/s41568-021-00387-5

PMCID:: PMC8669834

Abstract Article PDF–385K

Select item 848678515.

Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP–PKA signaling

Pedro Machado Almeida, Blanca Lago Solis, Luca Stickley, Alexis Feidler, Emi Nagoshi

Nat Commun. 2021; 12: 5758. Published online 2021 Oct 1. doi: 10.1038/s41467-021-26031-2

PMCID:: PMC8486785

Abstract Article PDF–3.2M

Select item 827785116.

Neurofibromin regulates metabolic rate via neuronal mechanisms in Drosophila

Valentina Botero, Bethany A. Stanhope, Elizabeth B. Brown, Eliza C. Grenci, Tamara Boto, Scarlet J. Park, Lanikea B. King, Keith R. Murphy, Kenneth J. Colodner, James A. Walker, Alex C. Keene, William W. Ja, Seth M. Tomchik

Nat Commun. 2021; 12: 4285. Published online 2021 Jul 13. doi: 10.1038/s41467-021-24505-x