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Select item 110607341.

BAP1 is required prenatally for differentiation and maintenance of postnatal murine enteric nervous system

Sabine Schneider, Jessica B. Anderson, Rebecca P. Bradley, Katherine Beigel, Christina M. Wright, Beth A. Maguire, Guang Yan, Deanne M. Taylor, J. William Harbour, Robert O. Heuckeroth

J Clin Invest. 2024 May 1; 134(9): e177771. Published online 2024 Mar 12. doi: 10.1172/JCI177771

PMCID:: PMC11060734

Abstract Article PDF–4.4M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108504913.

Crosstalk of HDAC4, PP1, and GSDMD in controlling pyroptosis

Weilv Xu, Qiao Jin, Xinyue Li, Danyue Li, Xinyu Fu, Nan Chen, Qian Lv, Yuhua Shi, Suhui He, Lu Dong, Yang Yang, Yuqi Yan, Fushan Shi

Cell Death Dis. 2024 Feb; 15(2): 115. Published online 2024 Feb 7. doi: 10.1038/s41419-024-06505-z

PMCID:: PMC10850491

Abstract Article PDF–7.0M

Select item 101847034.

WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis

Jincheng Liu, Yunhao You, Zhenqian Sun, Lu Zhang, Xiang Li, Zihan Dai, Jinlong Ma, Yunzhen Chen, Guangjun Jiao

Stem Cells Transl Med. 2023 May; 12(5): 307–321. Published online 2023 Apr 3. doi: 10.1093/stcltm/szad020

PMCID:: PMC10184703

Abstract Article PDF–61M

Select item 100997075.

Cytoplasmic HDAC4 recovers synaptic function in the 3×Tg mouse model of Alzheimer's disease

Claudia Colussi, Giuseppe Aceto, Cristian Ripoli, Alessia Bertozzi, Domenica Donatella Li Puma, Elena Paccosi, Marcello D'Ascenzo, Claudio Grassi

Neuropathol Appl Neurobiol. 2023 Feb; 49(1): e12861. Published online 2022 Nov 15. doi: 10.1111/nan.12861

PMCID:: PMC10099707

Abstract Article PDF–2.4M

Select item 100892106.

SIK3–HDAC4 in the suprachiasmatic nucleus regulates the timing of arousal at the dark onset and circadian period in mice

Fuyuki Asano, Staci J. Kim, Tomoyuki Fujiyama, Chika Miyoshi, Noriko Hotta-Hirashima, Nodoka Asama, Kanako Iwasaki, Miyo Kakizaki, Seiya Mizuno, Michihiro Mieda, Fumihiro Sugiyama, Satoru Takahashi, Shoi Shi, Arisa Hirano, Hiromasa Funato, Masashi Yanagisawa

Proc Natl Acad Sci U S A. 2023 Mar 14; 120(11): e2218209120. Published online 2023 Mar 6. doi: 10.1073/pnas.2218209120

PMCID:: PMC10089210

Abstract Article PDF–3.1M

Select item 98207227.

Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice

Alessandra Renzini, Eva Pigna, Marco Rocchi, Alessia Cedola, Giuseppe Gigli, Viviana Moresi, Dario Coletti

Int J Mol Sci. 2023 Jan; 24(1): 98. Published online 2022 Dec 21. doi: 10.3390/ijms24010098

PMCID:: PMC9820722

Abstract Article PDF–1.9M

Select item 92749498.

SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis

Zhen-Mi Liu, Xi Wang, Chen-Xi Li, Xue-Yan Liu, Xiao-Jing Guo, Yang Li, You-Lian Chen, Hong-Xing Ye, Huai-Sheng Chen

J Innate Immun. 2022 Jul; 14(4): 366–379. Published online 2022 Apr 22. doi: 10.1159/000518277

PMCID:: PMC9274949

Abstract Article PDF–2.0M

Select item 90351019.

Histone Deacetylase 5 is a Phosphorylation Substrate of Protein Kinase D in Osteoclasts

Carina Mello Guimaraes Meyers, Samuel D Burciaga, Bora Faulkner, Parandis Kazemi, Jacob M Cohn, Kim C Mansky, Eric D Jensen

Bone. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Bone. 2022 Jun; 159: 116393. Published online 2022 Mar 19. doi: 10.1016/j.bone.2022.116393

PMCID:: PMC9035101

Abstract Article PDF–2.8M

Select item 897800310.

m⁶A demethylase ALKBH5 drives denervation‐induced muscle atrophy by targeting HDAC4 to activate FoxO3 signalling

Yuantong Liu, Tianjian Zhou, Qinghe Wang, Runhan Fu, Zengfu Zhang, Nandi Chen, Zhizhong Li, Guoyong Gao, Songlin Peng, Dazhi Yang

J Cachexia Sarcopenia Muscle. 2022 Apr; 13(2): 1210–1223. Published online 2022 Feb 9. doi: 10.1002/jcsm.12929

PMCID:: PMC8978003

Abstract Article PDF–20M

Select item 897796811.

Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy

Alessandra Renzini, Nicoletta Marroncelli, Giorgia Cavioli, Silvia Di Francescantonio, Laura Forcina, Alessandro Lambridis, Eros Di Giorgio, Sergio Valente, Antonello Mai, Claudio Brancolini, Claudia Giampietri, Alessandra Magenta, Francesca De Santa, Sergio Adamo, Dario Coletti, Viviana Moresi

J Cachexia Sarcopenia Muscle. 2022 Apr; 13(2): 1339–1359. Published online 2022 Feb 15. doi: 10.1002/jcsm.12891

PMCID:: PMC8977968

Abstract Article PDF–24M

Select item 888688912.

Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development

Nayoung Ha, Jian Sun, Qian Bian, Dandan Wu, Xudong Wang

Front Physiol. 2022; 13: 819619. Published online 2022 Feb 15. doi: 10.3389/fphys.2022.819619

PMCID:: PMC8886889

Abstract Article PDF–4.7M

Select item 885366513.

A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair

Sergio Velasco-Aviles, Nikiben Patel, Angeles Casillas-Bajo, Laura Frutos-Rincón, Enrique Velasco, Juana Gallar, Peter Arthur-Farraj, Jose A Gomez-Sanchez, Hugo Cabedo

eLife. 2022; 11: e72917. Published online 2022 Jan 25. doi: 10.7554/eLife.72917

PMCID:: PMC8853665

Abstract Article PDF–42M

Select item 836925614.

Histone deacetylase 4 deletion results in abnormal chondrocyte hypertrophy and premature ossification from collagen type 2α1-expressing cells

Guoqing Du, Chuan Xiang, Xiaowen Sang, Xiang Wang, Ying Shi, Nan Wang, Shaowei Wang, Pengcui Li, Xiaochun Wei, Min Zhang, Lilan Gao, Hongsheng Zhan, Lei Wei

Mol Med Rep. 2020 Nov; 22(5): 4031–4040. Published online 2020 Aug 27. doi: 10.3892/mmr.2020.11465

PMCID:: PMC8369256

Abstract Article PDF–948K

Select item 831323915.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 819984316.

HDAC4 induces the development of asthma by increasing Slug-upregulated CXCL12 expression through KLF5 deacetylation

Wendi Wei, Weida Chen, Naifeng He

J Transl Med. 2021; 19: 258. Published online 2021 Jun 12. doi: 10.1186/s12967-021-02812-7

PMCID:: PMC8199843

Abstract Article PDF–1.1M

Select item 794807617.

Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation

Qi Yang, Jielin Tang, Chonghui Xu, He Zhao, Yuan Zhou, Yanyi Wang, Min Yang, Xinwen Chen, Jizheng Chen

J Mol Cell Biol. 2020 Dec; 12(12): 933–945. Published online 2021 Feb 4. doi: 10.1093/jmcb/mjaa043

PMCID:: PMC7948076

Abstract Article PDF–1.1M

Select item 793877018.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 788457219.

CaMKII and PKA-dependent phosphorylation co-regulate nuclear localization of HDAC4 in adult cardiomyocytes

Kathryn G. Helmstadter, Senka Ljubojevic-Holzer, Brent M. Wood, Khanha D. Taheri, Simon Sedej, Jeffrey R. Erickson, Julie Bossuyt, Donald M. Bers

Basic Res Cardiol. 2021; 116(1): 11. Published online 2021 Feb 15. doi: 10.1007/s00395-021-00850-2

PMCID:: PMC7884572

Abstract Article PDF–6.2M

Select item 732990020.

A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction

Tadatoshi Sato, Shiv Verma, Christian D. Castro Andrade, Maureen Omeara, Nia Campbell, Jialiang S. Wang, Murat Cetinbas, Audrey Lang, Brandon J. Ausk, Daniel J. Brooks, Ruslan I. Sadreyev, Henry M. Kronenberg, David Lagares, Yuhei Uda, Paola Divieti Pajevic, Mary L. Bouxsein, Ted S. Gross, Marc N. Wein

Nat Commun. 2020; 11: 3282. Published online 2020 Jul 1. doi: 10.1038/s41467-020-17099-3

PMCID:: PMC7329900

Abstract Article PDF–3.7M

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