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Select item 112751571.

Structural Analysis of the ESCRT-III Regulator Lethal(2) Giant Discs/Coiled-Coil and C2 Domain-Containing Protein 1 (Lgd/CC2D1)

Thomas Breuer, Christine Tibbe, Tobias Troost, Thomas Klein

Cells. 2024 Jul; 13(14): 1174. Published online 2024 Jul 10. doi: 10.3390/cells13141174

PMCID:: PMC11275157

Abstract Article PDF–5.6M

Select item 108477252.

Bone morphogenetic protein signaling: the pathway and its regulation

Takuya Akiyama, Laurel A Raftery, Kristi A Wharton

Genetics. 2024 Feb; 226(2): iyad200. Published online 2023 Dec 20. doi: 10.1093/genetics/iyad200

PMCID:: PMC10847725

Abstract Article PDF–6.8M

Select item 93206893.

Using Drosophila melanogaster to Analyse the Human Paralogs of the ESCRT-III Core Component Shrub/CHMP4/Snf7 and Its Interactions with Members of the LGD/CC2D1 Family

Miriam Baeumers, Katharina Schulz, Thomas Klein

Int J Mol Sci. 2022 Jul; 23(14): 7507. Published online 2022 Jul 6. doi: 10.3390/ijms23147507

PMCID:: PMC9320689

Abstract Article PDF–4.2M

Select item 89099424.

Inter-Species Rescue of Mutant Phenotype—The Standard for Genetic Analysis of Human Genetic Disorders in Drosophila melanogaster Model

Alexandru Al. Ecovoiu, Attila Cristian Ratiu, Miruna Mihaela Micheu, Mariana Carmen Chifiriuc

Int J Mol Sci. 2022 Mar; 23(5): 2613. Published online 2022 Feb 27. doi: 10.3390/ijms23052613

PMCID:: PMC8909942

Abstract Article PDF–1.3M

Select item 84660585.

The Role of Intracellular Trafficking of Notch Receptors in Ligand-Independent Notch Activation

Judith Hounjet, Marc Vooijs

Biomolecules. 2021 Sep; 11(9): 1369. Published online 2021 Sep 16. doi: 10.3390/biom11091369

PMCID:: PMC8466058

Abstract Article PDF–2.2M

Select item 77545976.

Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery

Miriam Baeumers, Kristina Ruhnau, Thomas Breuer, Hendrik Pannen, Bastian Goerlich, Anna Kniebel, Sebastian Haensch, Stefanie Weidtkamp-Peters, Lutz Schmitt, Thomas Klein

BMC Biol. 2020; 18: 200. Published online 2020 Dec 22. doi: 10.1186/s12915-020-00933-x

PMCID:: PMC7754597

Abstract Article PDF–15M

Select item 76065237.

Understanding microcephaly through the study of centrosome regulation in Drosophila neural stem cells

Beverly V. Robinson, Victor Faundez, Dorothy A. Lerit

Biochem Soc Trans. Author manuscript; available in PMC 2020 Nov 3.

Published in final edited form as: Biochem Soc Trans. 2020 Oct 30; 48(5): 2101–2115. doi: 10.1042/BST20200261

PMCID:: PMC7606523

Abstract Article PDF–1.7M

Select item 69615788.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 67773569.

The auxiliary ESCRT complexes provide robustness to cold in poikilothermic organisms

Miriam Bäumers, Sven Klose, Christian Brüser, Carl Haag, Sebastian Hänsch, Hendrik Pannen, Stefanie Weidtkamp-Peters, Michael Feldbrügge, Thomas Klein

Biol Open. 2019 Sep 15; 8(9): bio043422. Published online 2019 Aug 14. doi: 10.1242/bio.043422

PMCID:: PMC6777356

Abstract Article PDF–11M

Select item 623332310.

Integration of Drosophila and Human Genetics to understand Notch signaling related diseases

Jose L. Salazar, Shinya Yamamoto

Adv Exp Med Biol. Author manuscript; available in PMC 2018 Nov 13.

Published in final edited form as: Adv Exp Med Biol. 2018; 1066: 141–185. doi: 10.1007/978-3-319-89512-3_8

PMCID:: PMC6233323

Abstract Article PDF–2.0M

Select item 589891211.

A gene-specific T2A-GAL4 library for Drosophila

Pei-Tseng Lee, Jonathan Zirin, Oguz Kanca, Wen-Wen Lin, Karen L Schulze, David Li-Kroeger, Rong Tao, Colby Devereaux, Yanhui Hu, Verena Chung, Ying Fang, Yuchun He, Hongling Pan, Ming Ge, Zhongyuan Zuo, Benjamin E Housden, Stephanie E Mohr, Shinya Yamamoto, Robert W Levis, Allan C Spradling, Norbert Perrimon, Hugo J Bellen

eLife. 2018; 7: e35574. Published online 2018 Mar 22. doi: 10.7554/eLife.35574

PMCID:: PMC5898912

Abstract Article PDF–4.9M

Select item 570780512.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 569508513.

New genes often acquire male-specific functions but rarely become essential in Drosophila

Shu Kondo, Jeffrey Vedanayagam, Jaaved Mohammed, Sogol Eizadshenass, Lijuan Kan, Nan Pang, Rajaguru Aradhya, Adam Siepel, Josefa Steinhauer, Eric C. Lai

Genes Dev. 2017 Sep 15; 31(18): 1841–1846. doi: 10.1101/gad.303131.117

PMCID:: PMC5695085

Abstract Article PDF–3.0M

Select item 568900214.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 552816615.

Structural basis for regulation of ESCRT-III complexes by Lgd

Brian J. McMillan, Christine Tibbe, Andrew Drabek, Tom C. M. Seegar, Stephen C. Blacklow, Thomas Klein

Cell Rep. Author manuscript; available in PMC 2018 May 30.

Published in final edited form as: Cell Rep. 2017 May 30; 19(9): 1750–1757. doi: 10.1016/j.celrep.2017.05.026

PMCID:: PMC5528166

Abstract Article PDF–1.1M

Select item 492804716.

Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome

Heath A. MacMillan, Jose M. Knee, Alice B. Dennis, Hiroko Udaka, Katie E. Marshall, Thomas J. S. Merritt, Brent J. Sinclair

Sci Rep. 2016; 6: 28999. Published online 2016 Jun 30. doi: 10.1038/srep28999

PMCID:: PMC4928047

Abstract Article PDF–3.1M

Select item 480554517.

A genome-wide resource for the analysis of protein localisation in Drosophila

Mihail Sarov, Christiane Barz, Helena Jambor, Marco Y Hein, Christopher Schmied, Dana Suchold, Bettina Stender, Stephan Janosch, Vinay Vikas KJ, RT Krishnan, Aishwarya Krishnamoorthy, Irene RS Ferreira, Radoslaw K Ejsmont, Katja Finkl, Susanne Hasse, Philipp Kämpfer, Nicole Plewka, Elisabeth Vinis, Siegfried Schloissnig, Elisabeth Knust, Volker Hartenstein, Matthias Mann, Mani Ramaswami, K VijayRaghavan, Pavel Tomancak, Frank Schnorrer

eLife. 2016; 5: e12068. Published online 2016 Feb 20. doi: 10.7554/eLife.12068

PMCID:: PMC4805545

Abstract Article PDF–9.1M

Select item 479578118.

The Extracellular and Cytoplasmic Domains of Syndecan Cooperate Postsynaptically to Promote Synapse Growth at the Drosophila Neuromuscular Junction

Margaret U. Nguyen, Jereen Kwong, Julia Chang, Victoria G. Gillet, Rachel M. Lee, Karl Gregory Johnson

PLoS One. 2016; 11(3): e0151621. Published online 2016 Mar 17. doi: 10.1371/journal.pone.0151621

PMCID:: PMC4795781

Abstract Article PDF–8.6M

Select item 473800519.

Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes

Sadhna Phanse, Cuihong Wan, Blake Borgeson, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Bezginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, W. Brent Derry, Elisabeth R. Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili

Data Brief. 2016 Mar; 6: 715–721. Published online 2015 Dec 12. doi: 10.1016/j.dib.2015.11.062

PMCID:: PMC4738005

Abstract Article PDF–205K

Select item 469785220.

The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling

Nadja Drusenheimer, Bernhard Migdal, Sandra Jäckel, Lena Tveriakhina, Kristina Scheider, Katharina Schulz, Jieny Gröper, Karl Köhrer, Thomas Klein

PLoS Genet. 2015 Dec; 11(12): e1005749. Published online 2015 Dec 31. doi: 10.1371/journal.pgen.1005749

PMCID:: PMC4697852

Abstract Article PDF–21M

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