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Select item 114086101.

Prevalent Fast Evolution of Genes Involved in Heterochromatin Functions

Leila Lin, Yuheng Huang, Jennifer McIntyre, Ching-Ho Chang, Serafin Colmenares, Yuh Chwen G Lee

Mol Biol Evol. 2024 Sep; 41(9): msae181. Published online 2024 Aug 27. doi: 10.1093/molbev/msae181

PMCID:: PMC11408610

Abstract Article PDF–1.6M

Select item 109457072.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 107548193.

dTrmt10A impacts Hsp70 chaperone m⁶A levels and the stress response in the Drosophila brain

Alexandra E. Perlegos, Xiuming Quan, Kirby M. Donnelly, Hui Shen, Emily J. Shields, Heidi Elashal, Kathy Fange Liu, Nancy M. Bonini

Sci Rep. 2023; 13: 22999. Published online 2023 Dec 28. doi: 10.1038/s41598-023-50272-4

PMCID:: PMC10754819

Abstract Article PDF–2.6M

Select item 106974164.

Systematic assessment of transcriptomic and metabolic reprogramming by blue light exposure coupled with aging

Jia Huang, Fan Zhou, Huanchan Zhou, Xiaoqi Zheng, Zhengyi Huo, Meng Yang, Zihe Xu, Runzhou Liu, Luoluo Wang, Xiaoyun Wang

PNAS Nexus. 2023 Dec; 2(12): pgad390. Published online 2023 Dec 5. doi: 10.1093/pnasnexus/pgad390

PMCID:: PMC10697416

Abstract Article PDF–1.3M

Select item 105938105.

Phase separation of BuGZ regulates gut regeneration and aging through interaction with m⁶A regulators

Qiaoqiao Zhang, Kai Deng, Mengyou Liu, Shengye Yang, Wei Xu, Tong Feng, Minwen Jie, Zhiming Liu, Xiao Sheng, Haiyang Chen, Hao Jiang

Nat Commun. 2023; 14: 6700. Published online 2023 Oct 23. doi: 10.1038/s41467-023-42474-1

PMCID:: PMC10593810

Abstract Article PDF–3.5M

Select item 103519206.

The Drosophila Nab2 RNA binding protein inhibits m⁶A methylation and male-specific splicing of Sex lethal transcript in female neuronal tissue

Binta Jalloh, Carly L Lancaster, J Christopher Rounds, Brianna E Brown, Sara W Leung, Ayan Banerjee, Derrick J Morton, Rick S Bienkowski, Milo B Fasken, Isaac J Kremsky, Matthew Tegowski, Kate Meyer, Anita Corbett, Ken Moberg

eLife. 2023; 12: e64904. Published online 2023 Jul 17. doi: 10.7554/eLife.64904

PMCID:: PMC10351920

Abstract Article PDF–3.4M

Select item 101923617.

Indel driven rapid evolution of core nuclear pore protein gene promoters

David W. J. McQuarrie, Adam M. Read, Frannie H. S. Stephens, Alberto Civetta, Matthias Soller

Sci Rep. 2023; 13: 8035. Published online 2023 May 17. doi: 10.1038/s41598-023-34985-0

PMCID:: PMC10192361

Abstract Article PDF–2.2M

Select item 101057368.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 93984529.

Species-specific chromatin landscape determines how transposable elements shape genome evolution

Yuheng Huang, Harsh Shukla, Yuh Chwen G Lee

eLife. 2022; 11: e81567. Published online 2022 Aug 23. doi: 10.7554/eLife.81567

PMCID:: PMC9398452

Abstract Article PDF–5.5M

Select item 866448610.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 821372711.

Hakai is required for stabilization of core components of the m⁶A mRNA methylation machinery

Praveen Bawankar, Tina Lence, Chiara Paolantoni, Irmgard U. Haussmann, Migle Kazlauskiene, Dominik Jacob, Jan B. Heidelberger, Florian M. Richter, Mohanakarthik P. Nallasivan, Violeta Morin, Nastasja Kreim, Petra Beli, Mark Helm, Martin Jinek, Matthias Soller, Jean-Yves Roignant

Nat Commun. 2021; 12: 3778. Published online 2021 Jun 18. doi: 10.1038/s41467-021-23892-5

PMCID:: PMC8213727

Abstract Article PDF–5.4M

Select item 804185112.

Role of Hakai in m⁶A modification pathway in Drosophila

Yanhua Wang, Lifeng Zhang, Hang Ren, Lijuan Ma, Jian Guo, Decai Mao, Zhongwen Lu, Lijun Lu, Dong Yan

Nat Commun. 2021; 12: 2159. Published online 2021 Apr 12. doi: 10.1038/s41467-021-22424-5

PMCID:: PMC8041851

Abstract Article PDF–3.1M

Select item 795840013.

mTORC1-chaperonin CCT signaling regulates m⁶A RNA methylation to suppress autophagy

Hong-Wen Tang, Jui-Hsia Weng, Wen Xing Lee, Yanhui Hu, Lei Gu, Sungyun Cho, Gina Lee, Richard Binari, Cathleen Li, Min En Cheng, Ah-Ram Kim, Jun Xu, Zhangfei Shen, Chiwei Xu, John M. Asara, John Blenis, Norbert Perrimon

Proc Natl Acad Sci U S A. 2021 Mar 9; 118(10): e2021945118. Published online 2021 Mar 1. doi: 10.1073/pnas.2021945118

PMCID:: PMC7958400

Abstract Article PDF–1.8M

Select item 788305614.

Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila

Lina Worpenberg, Chiara Paolantoni, Sara Longhi, Miriam M Mulorz, Tina Lence, Hans‐Hermann Wessels, Erik Dassi, Giuseppe Aiello, F X Reymond Sutandy, Marion Scheibe, Raghu R Edupuganti, Anke Busch, Martin M Möckel, Michiel Vermeulen, Falk Butter, Julian König, Michela Notarangelo, Uwe Ohler, Christoph Dieterich, Alessandro Quattrone, Alessia Soldano, Jean‐Yves Roignant

EMBO J. 2021 Feb 15; 40(4): e104975. Published online 2021 Jan 11. doi: 10.15252/embj.2020104975

PMCID:: PMC7883056

Abstract Article PDF–2.8M

Select item 673414515.

HITS-CLIP reveals sex-differential RNA binding and alterative splicing regulation of SRm160 in Drosophila

Chen Qiu, Yu Zhang, Yu-Jie Fan, Ting-Lin Pang, Yan Su, Shuai Zhan, Yong-Zhen Xu

J Mol Cell Biol. 2019 Feb; 11(2): 170–181. Published online 2018 May 10. doi: 10.1093/jmcb/mjy029

PMCID:: PMC6734145

Abstract Article PDF–1.4M

Select item 607860416.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 602596317.

Striking circadian neuron diversity and cycling of Drosophila alternative splicing

Qingqing Wang, Katharine C Abruzzi, Michael Rosbash, Donald C Rio

eLife. 2018; 7: e35618. Published online 2018 Jun 4. doi: 10.7554/eLife.35618

PMCID:: PMC6025963

Abstract Article PDF–3.0M

Select item 590071418.

Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m⁶A machinery component Wtap/Fl(2)d

Philip Knuckles, Tina Lence, Irmgard U. Haussmann, Dominik Jacob, Nastasja Kreim, Sarah H. Carl, Irene Masiello, Tina Hares, Rodrigo Villaseñor, Daniel Hess, Miguel A. Andrade-Navarro, Marco Biggiogera, Mark Helm, Matthias Soller, Marc Bühler, Jean-Yves Roignant

Genes Dev. 2018 Mar 1; 32(5-6): 415–429. doi: 10.1101/gad.309146.117

PMCID:: PMC5900714

Abstract Article PDF–8.4M

Select item 588966119.

Xio is a component of the Drosophila sex determination pathway and RNA N⁶-methyladenosine methyltransferase complex

Jian Guo, Hong-Wen Tang, Jing Li, Norbert Perrimon, Dong Yan

Proc Natl Acad Sci U S A. 2018 Apr 3; 115(14): 3674–3679. Published online 2018 Mar 19. doi: 10.1073/pnas.1720945115

PMCID:: PMC5889661

Abstract Article PDF–1.4M

Select item 581106020.

Chinmo prevents transformer alternative splicing to maintain male sex identity

Lydia Grmai, Bruno Hudry, Irene Miguel-Aliaga, Erika A. Bach

PLoS Genet. 2018 Feb; 14(2): e1007203. Published online 2018 Feb 1. doi: 10.1371/journal.pgen.1007203

PMCID:: PMC5811060

Abstract Article PDF–29M

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