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Select item 110701371.

Pathways controlling neurotoxicity and proteostasis in mitochondrial complex I deficiency

Vanitha Nithianandam, Souvarish Sarkar, Mel B Feany

Hum Mol Genet. 2024 May 15; 33(10): 860–871. Published online 2024 Feb 7. doi: 10.1093/hmg/ddae018

PMCID:: PMC11070137

Abstract Article PDF–1.6M

Select item 107182852.

Phospholipids can regulate complex I assembly independent of their role in maintaining mitochondrial membrane integrity

Anjaneyulu Murari, Shauna-Kay Rhooms, Divya Vimal, Kaniz Fatima Binte Hossain, Sanjay Saini, Maximino Villanueva, Michael Schlame, Edward Owusu-Ansah

Cell Rep. Author manuscript; available in PMC 2023 Dec 13.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112846. Published online 2023 Jul 29. doi: 10.1016/j.celrep.2023.112846

PMCID:: PMC10718285

Abstract Article PDF–2.8M

Select item 106228403.

Cardiolipin prolongs the lifetimes of respiratory proteins in Drosophila flight muscle

Mindong Ren, Yang Xu, Colin K.L. Phoon, Hediye Erdjument-Bromage, Thomas A. Neubert, Michael Schlame

J Biol Chem. 2023 Oct; 299(10): 105241. Published online 2023 Sep 9. doi: 10.1016/j.jbc.2023.105241

PMCID:: PMC10622840

Abstract Article PDF–1.2M

Select item 105574764.

Isoforms of the transcriptional cofactor SIN3 differentially regulate genes necessary for energy metabolism and cell survival

Anindita Mitra, Linh Vo, Imad Soukar, Ashlesha Chaubal, Miriam L. Greenberg, Lori A. Pile

Biochim Biophys Acta Mol Cell Res. Author manuscript; available in PMC 2023 Oct 6.

Published in final edited form as: Biochim Biophys Acta Mol Cell Res. 2022 Oct; 1869(10): 119322. Published online 2022 Jul 9. doi: 10.1016/j.bbamcr.2022.119322

PMCID:: PMC10557476

Abstract Article PDF–1.9M

Select item 101057365.

Next-generation large-scale binary protein interaction network for Drosophila melanogaster

Hong-Wen Tang, Kerstin Spirohn, Yanhui Hu, Tong Hao, István A. Kovács, Yue Gao, Richard Binari, Donghui Yang-Zhou, Kenneth H. Wan, Joel S. Bader, Dawit Balcha, Wenting Bian, Benjamin W. Booth, Atina G. Coté, Steffi de Rouck, Alice Desbuleux, Kah Yong Goh, Dae-Kyum Kim, Jennifer J. Knapp, Wen Xing Lee, Irma Lemmens, Cathleen Li, Mian Li, Roujia Li, Hyobin Julianne Lim, Yifang Liu, Katja Luck, Dylan Markey, Carl Pollis, Sudharshan Rangarajan, Jonathan Rodiger, Sadie Schlabach, Yun Shen, Dayag Sheykhkarimli, Bridget TeeKing, Frederick P. Roth, Jan Tavernier, Michael A. Calderwood, David E. Hill, Susan E. Celniker, Marc Vidal, Norbert Perrimon, Stephanie E. Mohr

Nat Commun. 2023; 14: 2162. Published online 2023 Apr 15. doi: 10.1038/s41467-023-37876-0

PMCID:: PMC10105736

Abstract Article PDF–3.2M

Select item 100741086.

Reverse electron transfer is activated during aging and contributes to aging and age‐related disease

Suman Rimal, Ishaq Tantray, Yu Li, Tejinder Pal Khaket, Yanping Li, Sunil Bhurtel, Wen Li, Cici Zeng, Bingwei Lu

EMBO Rep. 2023 Apr; 24(4): e55548. Published online 2023 Feb 16. doi: 10.15252/embr.202255548

PMCID:: PMC10074108

Abstract Article PDF–3.9M

Select item 100361227.

Resting mitochondrial complex I from Drosophila melanogaster adopts a helix-locked state

Abhilash Padavannil, Anjaneyulu Murari, Shauna-Kay Rhooms, Edward Owusu-Ansah, James A Letts

eLife. 2023; 12: e84415. Published online 2023 Mar 23. doi: 10.7554/eLife.84415

PMCID:: PMC10036122

Abstract Article PDF–12M

Select item 99815358.

A large-scale RNAi screen reveals that mitochondrial function is important for meiotic chromosome organization in oocytes

Karen Jule Nieken, Kathryn O’Brien, Alexander McDonnell, Liudmila Zhaunova, Hiroyuki Ohkura

Chromosoma. 2023; 132(1): 1–18. Published online 2023 Jan 17. doi: 10.1007/s00412-023-00784-9

PMCID:: PMC9981535

Abstract Article PDF–3.4M

Select item 99772799.

Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster

Ahmed-Noor A Agip, Injae Chung, Alvaro Sanchez-Martinez, Alexander J Whitworth, Judy Hirst

eLife. 2023; 12: e84424. Published online 2023 Jan 9. doi: 10.7554/eLife.84424

PMCID:: PMC9977279

Abstract Article PDF–6.3M

Select item 995345110.

Mitochondrial Neurodegeneration: Lessons from Drosophila melanogaster Models

Michele Brischigliaro, Erika Fernandez-Vizarra, Carlo Viscomi

Biomolecules. 2023 Feb; 13(2): 378. Published online 2023 Feb 16. doi: 10.3390/biom13020378

PMCID:: PMC9953451

Abstract Article PDF–1.6M

Select item 979472811.

The membrane domain of respiratory complex I accumulates during muscle aging in Drosophila melanogaster

Kaniz Fatima Binte Hossain, Anjaneyulu Murari, Bibhuti Mishra, Edward Owusu-Ansah

Sci Rep. 2022; 12: 22433. Published online 2022 Dec 27. doi: 10.1038/s41598-022-26414-5

PMCID:: PMC9794728

Abstract Article PDF–3.7M

Select item 964406412.

Loss of Drosophila Clueless differentially affects the mitochondrial proteome compared to loss of Sod2 and Pink1

Aditya Sen, Rachel T. Cox

Front Physiol. 2022; 13: 1004099. Published online 2022 Oct 26. doi: 10.3389/fphys.2022.1004099

PMCID:: PMC9644064

Abstract Article PDF–4.2M

Select item 909466713.

IDH2-mediated regulation of the biogenesis of the oxidative phosphorylation system

Anjaneyulu Murari, Naga S. V. Goparaju, Shauna-Kay Rhooms, Kaniz F. B. Hossain, Felix G. Liang, Christian J. Garcia, Cindy Osei, Tong Liu, Hong Li, Richard N. Kitsis, Rajesh Patel, Edward Owusu-Ansah

Sci Adv. 2022 May; 8(19): eabl8716. Published online 2022 May 11. doi: 10.1126/sciadv.abl8716

PMCID:: PMC9094667

Abstract Article PDF–21M

Select item 908704814.

Roles for Mitochondrial Complex I Subunits in Regulating Synaptic Transmission and Growth

Bhagaban Mallik, C. Andrew Frank

Front Neurosci. 2022; 16: 846425. Published online 2022 Apr 26. doi: 10.3389/fnins.2022.846425

PMCID:: PMC9087048

Abstract Article PDF–7.4M

Select item 885234815.

Regulation of Reverse Electron Transfer at Mitochondrial Complex I by Unconventional Notch Action in Cancer Stem Cells

Rani Ojha, Ishaq Tantray, Suman Rimal, Siddhartha Mitra, Sam Cheshier, Bingwei Lu

Dev Cell. Author manuscript; available in PMC 2023 Jan 24.

Published in final edited form as: Dev Cell. 2022 Jan 24; 57(2): 260–276.e9. doi: 10.1016/j.devcel.2021.12.020

PMCID:: PMC8852348

Abstract Article PDF–2.6M

Select item 880872616.

Genetic Reduction of Mitochondria Complex I Subunits is Protective against Cisplatin-Induced Neurotoxicity in Drosophila

Christopher M. Groen, Jewel L. Podratz, Joe Pathoulas, Nathan Staff, Anthony J. Windebank

J Neurosci. 2022 Feb 2; 42(5): 922–937. doi: 10.1523/JNEUROSCI.1479-20.2021

PMCID:: PMC8808726

Abstract Article PDF–4.4M

Select item 866448617.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 864520718.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 834666619.

Dissecting the concordant and disparate roles of NDUFAF3 and NDUFAF4 in mitochondrial complex I biogenesis

Anjaneyulu Murari, Shauna-Kay Rhooms, Christian Garcia, Tong Liu, Hong Li, Bibhuti Mishra, Cassie Deshong, Edward Owusu-Ansah

iScience. 2021 Aug 20; 24(8): 102869. Published online 2021 Jul 16. doi: 10.1016/j.isci.2021.102869

PMCID:: PMC8346666

Abstract Article PDF–6.1M

Select item 765970920.

An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function

Anjaneyulu Murari, Shauna-Kay Rhooms, Naga Sri Goparaju, Maximino Villanueva, Edward Owusu-Ansah

J Cell Biol. 2020 Oct 5; 219(10): e202001071. Published online 2020 Sep 16. doi: 10.1083/jcb.202001071

PMCID:: PMC7659709

Abstract Article PDF–7.1M

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